Traditional herbal medicine research methods : identification, analysis, bioassay, and pharmaceutical and clinical studies / / edited by Willow J.H. Liu

• Pubblicazione: Hoboken, N.J., : John Wiley & Sons, c2011
• Descrizione fisica: 1 online resource (490 p.)
• Disciplina: 615/.321072
• Soggetto topico: Herbs - Therapeutic use - Testing; Materia medica, Vegetable - Research
• Altri autori: LiuWillow J. H <1963-> (Willow Jiang Hua)
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Traditional Herbal Medicine Research Methods: Identification, Analysis, Bioassay, and Pharmaceutical and Clinical Studies; Contents; Preface; Contributors; Abbreviations; Chapter 1: Introduction to Traditional Herbal Medicines and Their Study; 1.1 DEFINITION AND TRENDS OF TRADITIONAL HERBAL MEDICINES; 1.2 RESEARCH AND DEVELOPMENT OF HERBAL MEDICINES; 1.3 COMMON MISTAKES SEEN IN RESEARCH ON TRADITIONAL HERBAL MEDICINES; 1.4 RESEARCH ON TRADITIONAL HERBS SHOULD REFER TO THEORIES AND CLINICAL APPLICATION OF TRADITIONAL MEDICINE; 1.5 BRIEF INTRODUCTION OF DIFFERENT SYSTEMS OF TRADITIONAL MEDICINE ; 1.6 REGULATION OF HERBAL MEDICINES AND THEIR PRODUCTS1.7 ACHIEVEMENTS AND CHALLENGES OF RESEARCH ON CHINESE HERBAL MEDICINES; REFERENCES; Chapter 2: Collection and Identifi cation of Raw Herbal Materials; 2.1 COLLECTION OF HERBAL MATERIALS; 2.2 METHODS FOR SPECIES IDENTIFICATION OF HERBAL MATERIALS; REFERENCES; Chapter 3: Extraction and Isolation of Compounds from Herbal Medicines; 3.1 COMPOUNDS IN PLANTS AND THEIR STRUCTURES AND PROPERTIES; 3.2 METHODS FOR EXTRACTION OF HERBAL MEDICINES; 3.3 METHODS FOR ISOLATION OF COMPOUNDS FROM HERBAL EXTRACTS ; 3.4 AN EXAMPLE OF EXTRACTION AND COMPOUND ISOLATION FROM HERBAL MEDICINEREFERENCES; Chapter 4: Identification and Structure Elucidation of Compounds from Herbal Medicines; 4.1 STRUCTURAL CHARACTERISTICS AND CHEMICAL IDENTIFICATION OF COMPOUNDS IN HERBAL MEDICINES; 4.2 BRIEF INTRODUCTION OF UV, IR, NMR, MS, AND OTHER SPECTRA; 4.3 IDENTIFICATION OF COMPOUNDS BY HPLC AND TLC; 4.4 IDENTIFICATION OF COMPOUNDS BY SPECTRA; 4.5 STRUCTURE ELUCIDATION OF UNKNOWN COMPOUNDS BY HYPHENATED TECHNIQUE; REFERENCES; Chapter 5: Bioassays for Screening and Functional Elucidation of Herbal Medicines ; 5.1 HISTORY OF SCREENING COMPOUNDS FROM NATURAL PRODUCTS FOR DRUG DEVELOPMENT5.2 BRIEF INTRODUCTION OF ENZYMES, RECEPTORS, CELLS, AND GENE EXPRESSION; 5.3 SELECTION OF BIOASSAY; 5.4 EVALUATION OF BIOASSAY RESULTS OF HERBAL SAMPLES; 5.5 ENZYME BINDING ASSAY; 5.6 RECEPTOR BINDING ASSAY; 5.7 GENE EXPRESSION ASSAYS; 5.8 NEW TECHNOLOGIES AND OTHER BIOASSAYS FOR SCREENING AND MECHANISM STUDY; 5.9 KEYS TO FUNCTIONAL MECHANISM STUDY OF HERBAL MEDICINES; 5.10 EXAMPLE 1. SCREENING AND EVALUATION OF ESTROGENIC ACTIVITY OF HERBAL MEDICINES ; 5.11 EXAMPLE 2. FUNCTIONAL ELUCIDATION OF BLACK COHOSH FOR MENOPAUSE SYMPTOMSREFERENCES; Chapter 6: Functional Evaluation of Herbal Medicines by Animal Experiments; 6.1 PURPOSES AND SIGNIFICANCE OF PHARMACOLOGICAL RESEARCH FOR HERBAL MEDICINES; 6.2 CHARACTERISTICS OF PHARMACOLOGICAL RESEARCH OF HERBAL MEDICINES; 6.3 DESIGN OF PHARMACOLOGICAL STUDY ON HERBAL MEDICINES; 6.4 EXAMPLES OF IN VIVO EXPERIMENTS FOR HERBAL EXTRACTS; REFERENCES; Chapter 7: Safety Pharmacology and Toxicity Study of Herbal Medicines; 7.1 SAFETY PHARMACOLOGY; 7.2 ACUTE TOXICITY STUDY; 7.3 CHRONIC TOXICITY STUDY ; 7.4 SPECIAL TOXICITY STUDY
• Sommario/riassunto: This book introduces the methodology for collection and identification of herbal materials, extraction and isolation of compounds from herbs, in vitro bioassay, in vivo animal test, toxicology, and clinical trials of herbal research. To fully understand and make the best use of herbal medicines requires the close combination of chemistry, biochemistry, biology, pharmacology, and clinical science. Although there are many books about traditional medicines research, they mostly focus on either chemical or pharmacological study results of certain plants. This book, however, covers th
• Titolo autorizzato: Traditional herbal medicine research methods
• ISBN: 9786612904851; 9780470922668; 0470922664; 9781282904859; 128290485X; 9780470920824; 0470920823; 9780470921340; 047092134X
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910811046903321
• Lo trovi qui: Univ. Federico II