Small Animal Toxicology Essentials

• Autore: Wismer Tina
• Pubblicazione: Newark : , : John Wiley & Sons, Incorporated, , 2025; ©2025
• Edizione: 2nd ed.
• Descrizione fisica: 1 online resource (413 pages)
• Disciplina: 636.089/59
• Soggetto topico: Poisoning - veterinary; Poisoning - therapy; Pets
• Nota di contenuto: Cover -- Title Page -- Copyright Page -- Dedication -- Contents -- Contributors -- Preface -- Acknowledgement -- Section 1 Fundamentals of Veterinary Clinical Toxicology -- Chapter 1 General Toxicologic Principles -- Introduction -- Definitions -- Toxicant -- Toxin -- Toxicity -- Acute Toxicity -- Subacute Toxicity -- Subchronic Toxicity -- Chronic Toxicity -- Dose -- Dosage -- Lethal Dosage (ld) -- Median Lethal Dosage (ld50) -- Parts per Million (ppm) -- Hazard (risk) -- Classification of toxicants -- Spectrum of undesired Effects -- Idiosyncratic Reactions -- Immediate Vs. Delayed Reactions -- Reversible Vs. Irreversible Damage -- Local Vs. Systemic Effects -- Interaction of chemicals -- Characteristics of exposure -- Route and site of exposure -- Duration and frequency of exposure -- Dose-response Relationship -- Therapeutic Index -- Variation In toxic Responses -- Developmental and reproductive Toxicity -- Toxicokinetics -- Absorption -- Distribution -- Metabolism -- Elimination -- References -- Chapter 2 Incidence of poisoning In small Animals -- Introduction -- Demographics -- Agents -- Signs and outcomes -- Conclusion -- References -- Chapter 3 Toxicology Information Resources -- Introduction -- Evaluation of resources -- Types of resources -- Peer-reviewed Journals -- Textbooks -- Computer Databases and internet Sites -- Veterinary Diagnostic Laboratories -- Poison Control Centers -- Veterinary Telemedicine -- Summary -- Acknowledgements -- References -- Chapter 4 Taking A toxicologic History -- Introduction -- Patient Presentation -- Medical Record -- Client Information -- Patient Information -- Clinical Status -- Environmental Information -- Agent Information -- Exposure Information -- Implemented Treatment -- Telephone Triage -- Conclusion -- References -- Chapter 5 Essential Calculations -- Introduction -- Terminology. ; Essential Questions: Taking A history -- Essential Conversions -- A Note On density -- Salicylates -- Vitamins -- Chocolate -- Essential Solutions -- References -- Chapter 6 Initial Management of Acute intoxications -- Telephone Triage -- Hospital Presentation -- Triage -- Initial Assessment and stabilization -- Vascular Access -- Diagnostics -- Baseline Assessment -- Initial Decontamination -- Gastrointestinal Decontamination -- Ocular Decontamination -- Dermal Decontamination -- Conclusion -- References -- Chapter 7 Decontamination Procedures -- Sources -- Clinical Effects -- Signs -- Management of exposures -- Precautions -- Oral Decontamination -- Decontamination For inhalation Exposures -- Dermal Decontamination -- Ocular Decontamination -- Prognosis -- References -- Chapter 8 Antidotes -- Introduction -- Chemical Antidotes -- Chelators -- Commercial Antibodies -- Enzyme Inhibitors -- Pharmacological Antidotes -- Atipamezole (antisedan®) -- Atropine -- Folinic Acid (leucovorin®) -- Flumazenil (romazicon®) -- Glucagon -- Hydroxocobalamin (cyanokit®) -- Hyperbaric Oxygen -- Methylene Blue -- N-acetylcysteine (mucomyst®, Acetadote®) -- Naloxone (narcan®) -- Pralidoxime (protopam®) -- Pyridostigmine (mestinon®) -- Pyridoxine -- Silymarin -- Yohimbine -- Functional Antidotes -- Acepromazine -- Bicarbonate, Sodium -- Chlorpromazine (thorazine®) -- Cyproheptadine (periactin®) -- Dantrolene -- Dextrose -- Hyperbaric Oxygen -- Methocarbamol (robaxin®) -- Nitroprusside -- Norepinephrine (levophed®) -- Octreotide -- Pamidronate (aredia®) -- Same (denosyl®, Zentonil®) -- Vitamin K1 -- Zoledronic Acid (zoledronate) -- References -- Chapter 9 Most Deadly Toxins -- investigating Fatal Suspected Poisonings -- Introduction -- Causes of sudden Death -- Baclofen -- 5-fluorouracil -- 5-hydroxytryptophan -- Calcium Channel Blockers -- Lamotrigine -- Hops. ; Blue Green Algae -- Metaldehyde -- Methomyl -- Diagnostic Approach -- History -- Sample Collection -- Sample Submission -- Common Non-toxicologic Rule-outs -- Conclusion -- References -- Chapter 10 Toxicologic Testing and Using diagnostic Laboratories -- Sources -- Diagnostics -- Environmental Samples -- Antemortem -- Postmortem -- Management of exposures -- References -- Section 2 A Systems-affected Approach to toxicology -- Chapter 11 Nervous System -- Introduction -- Anatomy and physiology -- Mechanisms of toxicologic Injury -- Patterns of toxicologic Injury -- Healing and repair -- References -- Chapter 12 Cardiovascular System -- Introduction -- Anatomy and physiology -- Mechanisms of toxic Injury to the Heart -- Patterns of toxic Injury to the Heart -- Direct Myocardial Injury -- Conduction Disturbances -- Cardiotoxic Agents -- Calcium Channel Blockers -- Beta-adrenergic Blocking Agents -- Angiotensin-converting Enzyme Inhibitors -- Angiotensin Ii Antagonists -- Cardiac Glycosides -- Pimobendan -- Sympathomimetics -- Methylxanthines -- Mechanisms of toxic Injury to the Vascular System -- Cholecalciferol -- Carbon Monoxide -- Conclusion -- References -- Chapter 13 Pulmonary System -- Introduction -- Anatomy and physiology -- Anatomy of the Respiratory Tract -- Mechanisms and patterns of respiratory Tract Injury -- Diagnostics and treatment -- References -- Chapter 14 Hepatobiliary System -- Introduction -- Anatomy and physiology -- Mechanisms of toxicologic Injury -- Free Radical-induced Injury -- Calcium Homeostasis Disruption -- Mitochondrial Injury -- Cytoskeletal Disruption -- Cholestasis -- Idiosyncratic Reactions -- Patterns of toxicologic Injury -- Hepatocellular Degeneration -- Hepatocellular Necrosis or Apoptosis -- Healing and repair -- References -- Chapter 15 Urinary System -- Introduction -- Anatomy and physiology. ; Mechanisms of toxicological Injury -- Patterns of toxicological Injury -- Healing and repair of the Urinary System -- References -- Chapter 16 Other Systems -- Introduction -- Alimentary Tract -- Oral Cavity -- Gastrointestinal Tract -- Hematopoietic -- Integumentary -- Musculoskeletal System -- Acknowledgements -- References -- Section 3 Specific Toxicants -- Chapter 17 Rodenticides -- Introduction -- Anticoagulant Rodenticides -- Sources and formulations -- Kinetics -- Mechanism of action -- Toxicity -- Clinical Effects -- Differential Diagnoses -- Diagnostics -- Management of exposures -- Prognosis -- Bromethalin -- Sources and formulations -- Kinetics -- Mechanism of action -- Toxicity -- Clinical Effects -- Differential Diagnoses -- Diagnostics -- Management of exposures -- Prognosis -- Cholecalciferol -- Sources and formulations -- Kinetics -- Mechanism of action -- Toxicity -- Clinical Effects -- Differential Diagnoses -- Diagnostics -- Management of exposures -- Prognosis -- Strychnine -- Sources and formulations -- Kinetics -- Mechanism of action -- Toxicity -- Clinical Effects -- Differential Diagnoses -- Diagnostics -- Management of exposures -- Prognosis -- Zinc Phosphide -- Sources and formulations -- Kinetics -- Mechanism of action -- Toxicity -- Clinical Effects -- Differential Diagnoses -- Diagnostics -- Management of exposures -- Prognosis -- References -- Chapter 18 Insecticides -- Introduction -- Amitraz -- Sources and formulations -- Kinetics -- Mechanism of action -- Toxicity -- Clinical Effects -- Differential Diagnosis -- Diagnostics -- Management of exposures -- Prognosis -- Isoxazolines -- Sources and formulations -- Kinetics -- Mechanism of action -- Toxicity -- Clinical Effects -- Differential Diagnosis -- Diagnostics -- Management of exposure -- Prognosis -- Organophosphorus and carbamate Insecticides. ; Sources and formulations -- Kinetics -- Mechanism of action -- Toxicity -- Clinical Effects -- Differential Diagnosis -- Diagnostics -- Postmortem -- Management of exposures -- Prognosis -- Pyrethrins and pyrethroids -- Sources and formulations -- Kinetics -- Mechanism of action -- Toxicity -- Clinical Effects -- Differential Diagnosis -- Diagnostics -- Management of exposures -- Prognosis -- Neonicotinoids -- Sources and formulations -- Kinetics -- Mechanism of action -- Toxicity -- Clinical Effects -- Diagnostics -- Management of exposure -- Prognosis -- Acknowledgments -- References -- Chapter 19 Other Pesticides -- Introduction -- Miscellaneous Insecticides and repellants -- Boric Acid and borates -- Diethyltoluamide -- Kinetics and toxicity -- Fungicides -- Toxicity -- Clinical Effects -- Diagnostics -- Management of exposures -- Herbicides -- Chlorophenoxy Herbicides -- Glyphosate -- Paraquat -- Diquat Dibromide -- Disodium Methanearsenate and monosodium Methanearsenate -- Molluscides -- Large Predator Control -- Sodium Fluoroacetate (compound 1080) -- Acknowledgments -- References -- Chapter 20 Plants -- Introduction -- Digestive System -- Aloe Spp. -- Asparagus Spp. -- Begonia Spp. -- Capsicum Spp. -- Chrysanthemum Spp. -- Clematis Spp. -- Cyclamen Spp. -- Insoluble Calcium Oxalate-containing Plants -- Ornamental Bulbs -- Cardiovascular System -- Cardiac Glycosides -- Grayanotoxins -- Liver -- Cycas Spp. and Zamia Spp. -- Urinary System -- Lilium Spp. -- Soluble Oxalate-containing Plants -- Central Nervous System -- Brunfelsia Spp. -- Multisystemic Effects -- Colchicum Autumnale -- Nontoxic Plants -- References -- Internet Resources -- Chapter 21 Dietary Supplements and herbs -- Introduction -- Sympathomimetics -- Sources and formulations -- Mechanism of action -- Kinetics -- Toxicity -- Clinical Signs -- Management of exposures. ; Methylxanthines.
• Sommario/riassunto: "The new edition of Small Animal Toxicology Essentials updates veterinary technicians with the newest toxicologic information necessary to evaluate the urgency of calls related to exposure of pets to potential poisons, to provide initial triage of cases, to provide guidelines for collection of samples for diagnostic purposes and for instituting appropriate nursing care. The new edition not only updates the most common toxins, but also expands on client communication methods (in person, on phone, email, social media, etc.) to provide valuable information that will allow veterinary technicians to discuss preventative measures that pet owners can take to minimize poisoning risks to pets. Awareness campaigns of potential seasonal toxins is invaluable. Overall, this textbook focuses on essential information required by veterinary technicians in order to be able to assist clients and veterinarians treating cases presented to the hospital. The team nature of veterinary medicine will be emphasized through discussion of clinical signs, differential diagnoses, obtaining a minimum database, laboratory sample collection and confirmatory testing, and case management recommendations. This provides the basis for a veterinary technician to anticipate what the veterinarian needs for proper patient evaluation, monitoring and treatment. While nursing care for each toxicant is highlighted, there is little emphasis on mechanisms of toxic action. Small Animal Toxicology Essentials is a valuable resource for veterinary technicians working in both small animal and emergency and critical care practices. Although there are several clinical toxicology texts available that are geared toward veterinary students and veterinarians, there are no texts that target veterinary technicians. One unique aspect of the textbook is the inclusion of example cases and self-assessment questions at the end of each chapter"--
• Titolo autorizzato: Small Animal Toxicology Essentials
• ISBN: 1-394-18014-4; 1-394-18013-6; 1-394-18012-8
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910998471203321
• Lo trovi qui: Univ. Federico II