Prostate Cancer : Methods and Protocols / / edited by Zoran Culig

• Pubblicazione: New York, NY : , : Springer New York : , : Imprint : Humana, , 2018
• Edizione: 1st ed. 2018.
• Descrizione fisica: 1 online resource (XI, 264 p. 45 illus., 40 illus. in color.)
• Disciplina: 614.5999
• Soggetto topico: Cancer; Cancer Biology
• Persona (resp. second.): CuligZoran
• Nota di contenuto: Generation of Prostate Cancer Patient-derived Xenografts to Investigate Mechanisms of Novel Treatments and Treatment Resistance -- Methods to Study Angiogenesis in a Mouse Model of Prostate Cancer -- Methodologies Applied to Establish Cell Cultures in Prostate Cancer -- Protocols for Migration and Invasion Studies in Prostate Cancer -- Transplantable Animal Studies and Whole-body Optical Imaging in Prostate Carcinoma -- Protocols for Tissue Microarrays in Prostate Cancer Studies -- Functional Studies on Steroid Receptors -- Protocols for Studies on TMPRSS/ERG in Prostate Cancer -- Protocols for the Study of Taxanes Chemosensitivity in Prostate Cancer -- A Method for Prostate and Breast Cancer Cell Spheroid Cultures using Gelatin Methacryloyl-based Hydrogels -- Protocols for Studies on Genetically Engineered Mouse Models in Prostate Cancer -- Protocols for Studies on Stromal Cells in Prostate Cancer -- Techniques for Evaluation of AR Transcriptional Output and Recruitment to DNA -- NMR-based Prostate Cancer Metabolomics -- Studies on Steroid Receptor Coactivators in Prostate Cancer.
• Sommario/riassunto: This volume presents methods and protocols on modern analysis of steroid receptor and prostate cancer function. Chapters detail androgen, androgen receptor action, anti-androgen enzalutamide, in vitro and in vivo models, imaging, gene fusions, and help facilitate studies with novel drugs including anti-androgens and chemotherapeutics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Prostate Cancer: Methods and Protocols aims to provide easily reproducible techniques.
• Titolo autorizzato: Prostate Cancer
• ISBN: 9781493978458; 1493978454
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9911154885303321
• Lo trovi qui: Univ. Federico II
• Serie: Methods in Molecular Biology, . 1940-6029 ; ; 1786