Mitochondrial biology [[electronic resource] ] : new perspectives / / [editors: Derek J. Chadwick and Jamie Goode]

• Pubblicazione: London, : John Wiley, 2007
• Descrizione fisica: 1 online resource (255 p.)
• Disciplina: 571.657
• Soggetto topico: Mitochondria; Cell membranes
• Altri autori: ChadwickDerek GoodeJamie
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: MITOCHONDRIAL BIOLOGY: NEW PERSPECTIVES; Contents; Chair's introduction; Outer mitochondrial membrane protein degradation by the proteasome; DISCUSSION; PA-GFP: a window into the subcellular adventures of the individual mitochondrion; DISCUSSION; Multiple functions of mitochondria-shaping proteins; DISCUSSION; Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators; DISCUSSION; Novel uncoupling proteins; DISCUSSION; Mitochondria as generators and targets of nitric oxide; DISCUSSION; Calcium signalling and mitochondrial motility; DISCUSSION ; Endoplasmic reticulum/mitochondria calcium cross-talkDISCUSSION; Mitochondrial ion channels in cardiac function and dysfunction; DISCUSSION; The mitochondrial permeability transition pore; DISCUSSION; Mechanisms of mitochondrial outer membrane permeabilization; DISCUSSION; Mitochondria and neurodegeneration; DISCUSSION; Mitochondrial dysfunction in mammalian ageing; DISCUSSION; Mitochondrial mutations: genotype to phenotype; DISCUSSION; Contributor Index; Subject Index
• Sommario/riassunto: With the recent renaissance in mitochondrial biology and increasing recognition of their role in many diseases, this book provides a timely summary of the current state-of-the-art in mitochondrial research. The book opens with the regulation of mitochondrial replication and biogenesis and reviews the mechanisms and functional consequences of mitochondrial fission and fusion. Further chapters address mitochondria and oxidative stress and their roles in cell signalling and cell death. The book includes extensive, fascinating discussion of the biochemistry of mitochondrial cell signalling (especi
• Titolo autorizzato: Mitochondrial biology
• ISBN: 1-281-13540-2; 9786611135409; 0-470-72520-6; 0-470-72519-2
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910840518703321
• Lo trovi qui: Univ. Federico II
• Serie: Novartis Foundation symposium ; ; 287.