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| Autore: |
Valentine Raymond C
|
| Titolo: |
Human Longevity
|
| Pubblicazione: | CRC Press, 2014 |
| Edizione: | 1st ed. |
| Descrizione fisica: | 1 online resource (248 p.) |
| Disciplina: | 612.6/7 |
| Soggetto topico: | Aging - Genetic aspects |
| Mitochondria | |
| Oxidative stress | |
| Omega-3 fatty acids - Health aspects | |
| Classificazione: | MED008000SCI049000TEC012000 |
| Altri autori: |
ValentineDavid L
|
| Note generali: | Description based upon print version of record. |
| Nota di bibliografia: | Includes bibliographical references at the end of each chapters. |
| Nota di contenuto: | Chapter 5: Remarkable Longevity of Queens of Social Insects Likely Involves Dietary Manipulation to Minimize Levels of Polyunsaturates and Decrease Membrane PeroxidationChapter 6: Membrane Peroxidation Hypothesis Helps Explain Longevity in Birds, Rodents, and Whales; Chapter 7: Did Longevity Help Humans Become Super Humans?; Chapter 8: Mitochondrial Diseases and Aging Have Much in Common; Chapter 9: Revised Mitochondrial Hypothesis of Aging Highlights Energy Deficiency Caused by Errors of Replication (Mutations) of mtDNA; Chapter 10: Benefits of Polyunsaturated Mitochondrial Membranes |
| Chapter 16: Uncoupling Proteins (UCPs) of Mitochondria Purposely Waste Energy to Prevent Membrane DamageChapter 17: Mitochondrial Fission Protects against Oxidative Stress by Minting a Continuous Supply of Cardiolipin and Other Polyunsaturated Phospholipids; Chapter 18: Mitophagy Eliminates Toxic Mitochondria; Chapter 19: Longevity Genes Likely Protect Membranes; Chapter 20: Aging as a Cardiolipin Disease That Can Be Treated; Back Cover | |
| Sommario/riassunto: | More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age as our mitochondria age. It suggests a revised version of Harman's famous hypothesis featuring mitochondrial oxidative and energy stresses as the root causes of aging. Human cells are protected from the ravages of aging by a battery of defensive systems including some novel mechanisms against membran |
| Titolo autorizzato: | Human Longevity ![]() |
| ISBN: | 1-04-021241-7 |
| 0-429-16877-2 | |
| 1-4665-9487-X | |
| Formato: | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910962495303321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |