Handbook of methods and instrumentation in separation science . Volume 1 / / editors, Ian D. Wilson, Colin F. Poole

• Pubblicazione: Boston, : Elsevier / AP Academic Press, c2009
• Descrizione fisica: 1 online resource (881 p.)
• Disciplina: 660.2842
• Soggetto topico: Separation (Technology); Chromatographic analysis
• Altri autori: PooleC. F WilsonIan D
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Front cover; Handbook of Methods and Instrumentation in Separation Science Volume 1; Copyright page; Preface; Contents; Affinity Membranes; General Characteristics of Membrane Chromatography; Membrane Geometry; Membrane Material, Activation and Ligand Coupling; Affinity Ligands; Scale-up; Applications; Conclusions; Further Reading; Affinity Partitioning in Aqueous Two-Phase Systems; Aqueous Two-phase Systems in General; Affinity Partitioning; A Simple Theory for Affinity Partitioning; Experimental Results; Types of Affinity Ligands Used; Preparative Extractions; Countercurrent Distribution ; Use of Dextran as a Ligand CarrierUse of a Third Polymer as Ligand Carrier; Chiral Affinity Partitioning; Analytical Uses; Multiphase Systems; Semi-organic Systems; Affinity Partitioning of Nucleic Acids and Bioparticles; Future Prospects; Conclusions; Further Reading; Affinity Separations; Introduction; Biological Recognition; The Affinity Process; Matrices; Covalent Bonding; Intermolecular Binding Forces; Analytical Scale-Up; Affinity versus Traditional Media; Synthetic Ligands; Rational Design of Affinity Ligands; Combinatorial Libraries; Regulations and Drug Master Files ; Alternative Affinity ApproachesAffinity Membranes; Conclusion; Further Reading; Analytical Ultracentrifugation; Theoretical Background; Instrumentation and Experimental Considerations; Data Analysis Methods; Sedimentation Velocity; Sedimentation Equilibrium; Conclusions; Further Reading; Biochemical Engineering Aspects of Affinity Separations; Introduction; Position in Process Flow Sheet - Direct Recovery; Choice of an Appropriate Affinity Ligand and Immobilization to a Support; Operating Protocols, Equipment, Monitoring and Control; Scale-up and Validation; Optimization ; Theoretical ModellingEconomic Considerations; Conclusions and Future Prospects; Further Reading; Centrifugation; Introduction; Theory; Types of Separation; Centrifugal Equipment; Acknowledgments; Further Reading; Chromatography; Introduction; The Family of Chromatographic Techniques; Mode of Zone Displacement; Chromatogram; Peak Shape Models; Flow through Porous Media; Zone Broadening; Separation Quality; General Elution Problem; Multidimensional and Multimodal Chromatography; Mode Selection; Instrumentation; Conclusion; Further Reading; Countercurrent Chromatography: Extrusion-Elution ; IntroductionAdvantages of a Liquid Stationary Phase; Countercurrent Chromatographs; Band Broadening inside the Column; Resolution between Peaks inside the Column; The Elution-Extrusion Method; Practical Demonstration; Estimation of the Hydrophobicity of a Natural Extract; Conclusion; Further Reading; Countercurrent Chromatography: Instrumentation; Introduction; What is Countercurrent Chromatography?; Apparatus; Theory; Resolution; Solvent Systems; Other Chromatographic Approaches; pH-Zone Refining; Conclusion; CCC Literature; Further Reading; Countercurrent Chromatography: Large-Scale ; Introduction
• Sommario/riassunto: This handbook is directed to the needs of scientists requiring concise overviews and targeted summaries of the main methods employed for separations. It is a work derived from the successful Encyclopedia of Separation Science with a new focus on the fundamentals of methods and instrumentation employed in separations. In a single source it affords access to general background material to enable the professional to quickly assimilate, sort and interpret the dense information associated with a comprehensive literature search. One-stop source for information on separation methods<b
• Titolo autorizzato: Handbook of methods and instrumentation in separation science
• ISBN: 1-282-69989-X; 9786612699894; 0-12-375727-4
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9911004781603321
• Lo trovi qui: Univ. Federico II