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Foundations of comparative genomics / / Arcady R. Mushegian



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Autore: Mushegian Arcady R Visualizza persona
Titolo: Foundations of comparative genomics / / Arcady R. Mushegian Visualizza cluster
Pubblicazione: Amsterdam ; ; Boston, : Academic Press, c2007
Edizione: 1st ed.
Descrizione fisica: 1 online resource (276 p.)
Disciplina: 572.8/6 22
572.86
Soggetto topico: Genomics
Gene mapping
Physiology, Comparative
Note generali: Description based upon print version of record.
Nota di bibliografia: Includes bibliographical references (p. 238-257) and index.
Nota di contenuto: The beginning of computational genomics -- Finding sequence similarities -- Homology: can we get it right? -- Getting ready for the era of comparative genomics: the importance of viruses -- The first fact of comparative genomics: protein sequences are remarkably resilient in evolution -- The second fact of comparative genomics: functional convergence at the molecular level -- Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches -- Prediction of function and reconstruction of metabolism: post-homology approaches -- Structural genomics: what does it tell us about life? -- How many protein families are there? -- Phylogenetic inference and the era of complete genomes -- Two stories about evolution -- Minimal and ancestral genomes -- Comparative genomics and systems biology.
Sommario/riassunto: This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as
Titolo autorizzato: Foundations of comparative genomics  Visualizza cluster
ISBN: 1-281-03696-X
9786611036966
0-08-054609-9
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910817454503321
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