Clinical pancreatology for practicing gastroenterologists and surgeons / / edited by J. Enrique Domínguez Muñoz

• Pubblicazione: Hoboken, New Jersey : , : Wiley Blackwell, , [2021]; ©2021
• Edizione: Second edition.
• Descrizione fisica: 1 online resource (749 pages)
• Disciplina: 616.37
• Soggetto topico: Pancreas - Diseases
• Persona (resp. second.): Domínguez-MuñozJ. Enrique
• Nota di contenuto: Cover -- Title Page -- Copyright Page -- Contents -- Contributors -- Foreword -- Preface -- Dedication -- Section I Acute Pancreatitis -- Chapter 1 Acute Pancreatitis: An Overview -- Introduction -- Causes -- Laboratory Diagnosis -- Imaging -- Risk Stratification -- Classification -- Treatment -- Prophylactic Antibiotics -- Nutrition -- Post-discharge Cholecystectomy -- Long-term Sequelae -- References -- Chapter 2 How to Deal with the Etiological Diagnosis of Acute Pancreatitis in Clinical Practice? -- Introduction -- Etiological Diagnosis -- Gallstone-induced Pancreatitis -- Microlithiasis -- Alcoholic Pancreatitis -- Drug-induced Pancreatitis -- Other Etiological Diagnoses of Acute Pancreatitis -- Hypercalcemia -- Hypertriglyceridemia -- Smoking -- Type 2 Diabetes Mellitus -- Pancreatobiliary Tumors -- Post-ERCP Pancreatitis -- Single and Double Balloon Enteroscopy -- Congenital Anomalies -- Idiopathic Acute Pancreatitis -- Investigative Work-up -- Concluding Remarks -- References -- Chapter 3 Definition of Complications and Severity of Acute Pancreatitis for Clinical Practice -- Background -- The Atlanta Classification 1992 -- The Revised Atlanta Classification 2012 -- Definition of Organ Failure and Complications in Acute Pancreatitis -- Organ Failure -- Local Complications -- Systemic Complications -- Definition of Severity in Acute Pancreatitis -- Mild Acute Pancreatitis -- Moderately Severe Acute Pancreatitis -- Severe Acute Pancreatitis -- Limitations of the Revised Atlanta Classification -- The Determinant-Based Classification -- Conclusion -- References -- Chapter 4 Early Prediction of Severity in Acute Pancreatitis: What can be Done in Clinical Practice? -- Introduction -- Available Prediction Tools -- Volume Deficit -- Inflammatory Response -- Host-related Characteristics -- Age and Comorbidity Burden. ; Obesity and Hypertriglyceridemia -- Degree of Parenchymal and Extra-parenchymal Injury -- Scoring Systems -- Limitations and Future of Current Scoring Systems and Predictive Markers -- Artificial Intelligence and Biomarkers: the Future? -- References -- Chapter 5 Role of CT Scan in Acute Pancreatitis: When is it Indicated and What Information can be Obtained? -- CT Imaging in Acute Pancreatitis -- Confirming the Diagnosis of AP -- Assessing the Etiology of Acute Pancreatitis -- Assessing the Prognosis of Acute Pancreatitis -- Identifying Local Complications Associated with Acute Pancreatitis -- Pancreatic Necrosis and Peripancreatic Fluid Collections -- Vascular Complications -- Other Complications -- Timing of CT in Acute Pancreatitis -- Limitations of CT Imaging -- Conclusion -- Disclosures -- References -- Chapter 6 Role of MRI in Acute Pancreatitis When is it Indicated and What Information can be Obtained? -- Introduction -- MRI and MRCP Protocol for Pancreas Examination -- Interstitial Edematous Pancreatitis -- Necrotizing Pancreatitis -- Complications of Acute Pancreatitis -- Fluid Collections -- Acute Peripancreatic Fluid Collection -- Acute Necrotic Collection -- Pseudocyst -- Walled-off Necrosis -- Vascular Complications -- References -- Chapter 7 Treatment of Acute Pancreatitis in The Emergency Room: What Should be Done During the First Hours of Disease? -- Introduction -- Early Diagnosis in the Emergency Room -- Initial Work-up for Etiology -- Severity Assessment, Triage, and Disposition -- Specialty Consultation -- Management -- First-line Medical Management: Fluid Resuscitation -- Type of Intravenous Fluid to Administer -- Antibiotics -- Pain Control -- Nutrition -- Summary -- References -- Chapter 8 Acute Pancreatitis: A Practical Guideline for the Monitoring and Treatment of Systemic Complications -- Introduction. ; Acute Pancreatitis and Systemic Complications: Definitions, Importance, and Incidence -- Monitoring Respiratory Function and Management of Respiratory Failure -- Shock: Volume Management and Hemodynamic Monitoring -- Acute Renal Failure: Early Detection and Management -- Other Systemic Complications Associated with Acute Pancreatitis -- Hypocalcemia -- Disseminated Intravascular Coagulation -- Gastrointestinal Bleeding -- Pancreatic Encephalopathy and Posterior Reversible Encephalopathy Syndrome -- Abdominal Compartment Syndrome -- References -- Chapter 9 Guidelines for the Treatment of Pain in Acute Pancreatitis -- Introduction -- Nonsteroidal Anti-inflammatory Drugs -- Opioid Analgesics -- Epidural Analgesia -- Local Anesthetics -- Summary -- References -- Chapter 10 Nutrition in the Acute Phase of Pancreatitis: Why, When, How and How Long? -- Why -- When -- How -- What to Feed -- References -- Chapter 11 Oral Refeeding in Acute Pancreatitis: When and How Should it be Restarted? -- Introduction -- What is the Optimal Timing of Refeeding in AP? -- How Should Oral Refeeding be Scheduled? -- What are the Predictors of Oral Feeding Intolerance in AP Patients? -- Summary and Recommendations -- References -- Chapter 12 Pharmacological Therapy for Acute Pancreatitis: Any Light at the End of the Tunnel? -- Introduction -- Calcium Toxicity -- Mitochondrial Dysfunction -- Autophagy -- Acinar Cell Secretion, Serine Proteases, and Serine Protein Kinases -- Immune Cells/Inflammation -- CFTR -- Design of Future Clinical Trials -- Conclusion -- References -- Chapter 13 Indication and Optimal Timing of ERCP in Acute Pancreatitis -- Introduction -- ERCP in the Setting of Acute Biliary Pancreatitis -- Urgent ERCP -- Elective ERCP -- Additional Applications of ERCP in the Setting of Acute Pancreatitis -- Conclusions -- Disclosures -- References. ; Chapter 14 How to Deal with Infected Pancreatic Necrosis? -- Introduction -- Prevention of Infection of (Peri)pancreatic Necrosis -- Diagnosis of Infected (Peri)pancreatic Necrosis -- How to Deal with Infected (Peri)pancreatic Necrosis -- Systemic Antibiotics -- Endoscopic or Percutaneous Drainage -- Endoscopic or Laparoscopic Necrosectomy -- References -- Chapter 15 Minimally Invasive Surgical Necrosectomy in Clinical Practice: Indications, Technical Issues, and Optimal Timing -- Introduction -- Percutaneous Drainage -- Sinus Tract Endoscopy -- Endoscopic (Endoluminal) Approach -- Retroperitoneal Approach -- Laparoscopic Transperitoneal Approach -- References -- Chapter 16 Endoscopic Necrosectomy in Clinical Practice: Indications, Technical Issues, and Optimal Timing -- Introduction -- Management of Symptomatic Pseudocysts -- Management of Symptomatic Walled-off Necrosis -- Indications and Timing for Intervention -- Choosing the Best Interventional Option: the Step-up Approach -- Methods of Endoscopic Necrosectomy and Stent Choice -- Conclusion -- References -- Chapter 17 Management of Acute Pancreatic Pseudocyst: When to Observe, When and How to Drain? -- Introduction -- Evaluation -- Drainage Therapy -- Disconnected Pancreatic Duct Syndrome -- Complications -- Conclusion -- References -- Chapter 18 The Disconnected Main Pancreatic Duct Syndrome: How to Proceed in Clinical Practice? -- Introduction -- Epidemiology -- Risk Factors and Predictors of DPDS -- Clinical Significance -- Clinical Presentation -- Diagnosis -- Treatment -- Conclusions -- References -- Chapter 19 Vasculature Complications in Pancreatitis: How to Deal with Them? -- Venous Complications -- Splanchnic Thrombosis Rates -- Risk Factors for Thrombosis -- Clinical Findings -- Screening -- Splenic Vein Thrombosis -- Portal Vein Thrombosis -- Management of Visceral Vein Thrombosis. ; Anticoagulation -- Surgical Management -- Miscellaneous Venous Complications -- Bowel Wall Ischemia -- Portal Vein-Pseudocyst Fistula -- Arterial Complications -- Pseudoaneurysm -- Pseudoaneurysm and Risk of Rupture -- Hemosuccus Pancreaticus -- Imaging of Pseudoaneurysm or Potential Hemorrhage -- Ruptured Pseudoaneurysm Management -- Summary -- References -- Chapter 20 Acute Relapsing Pancreatitis: What can be Done to Prevent Relapses? -- Introduction -- Definition -- Burden -- Demographics -- Etiology -- Diagnostic Work-up -- Natural History and Risk of Progression -- Preventing Recurrences and Disease Progression -- Conclusion -- Acknowledgment -- References -- Chapter 21 Diagnosis and Therapeutic Approach to Pancreatic Exocrine Insufficiency after Acute Pancreatitis -- Introduction -- Symptoms -- Diagnosis -- Management -- Summary -- References -- Chapter 22 Asymptomatic Chronic Elevation of Serum Pancreatic Enzymes: How to Deal with It? -- Introduction -- Physiology of Pancreatic Enzymes -- Pancreatic Abnormalities in Patients with Pancreatic Hyperenzymemia -- Pancreatic Hyperenzymemia: A Clue to Malignancy? -- Pancreatic Abnormalities at Second-level Imaging -- Gastrointestinal Diseases and Pancreatic Hyperenzymemia -- Inflammatory Bowel Disease -- Celiac Disease -- Liver Disease -- Others -- Macroenzymemia -- Systemic Conditions Associated with Hyperenzymemia -- Familial Aggregation and Genetics -- Drug-induced Hyperenzymemia -- Extrapancreatic Abnormalities in Patients with Hyperenzymemia -- Salivary Gland Diseases -- Renal Insufficiency -- Hyperenzymemia and Cancers -- Eating Disorders -- Others -- Benign Pancreatic Hyperenzymemia (Gullo Syndrome) -- Clinical Features -- Physiopathology -- Algorithm for Management of CAPH (Figure 22.2) -- Clinical History and Laboratory Evaluation -- Isolated Hyperamylasemia. ; Pancreatic Hyperamylasemia and/or Hyperlipasemia.
• Sommario/riassunto: "Since the book Clinical Pancreatology for practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and complications of acute pancreatitis is firmly rooted in clinical practice and has been the basis for the development of minimally invasive approaches to pancreatic necrosis. The etiopathogenic knowledge of chronic pancreatitis and other pancreatopaties, like that associated with diabetes mellitus, has developed significantly. Especially important has been the development of the field of cystic pancreatic tumours, which has been reflected in the publication of several guidelines and consensus reports over the last few years. Most research efforts have focused on pancreatic cancer, which have led and will further lead to a significant increase in the therapeutic armamentarium against this devastating disease. Finally, many newly published studies have changed the concept, causes, clinical relevance, diagnosis and treatment of exocrine pancreatic insufficiency. This new edition of Clinical Pancreatology for practising Gastroenterologists and Surgeons has enjoyed the collaboration of the world's leading experts in each of the areas of clinical Pancreatology with the aim of facilitating Gastroenterologists, Surgeons, Oncologists, Internists, Nutritionists, Diabetologists, Paediatricians, Radiologists, Pathologists and other specialists the decision making when facing patients with pancreatic diseases in their daily clinical practice. All in all, this book supplies an indispensable update of the relevant aspects of clinical Pancreatology"--
• Titolo autorizzato: Clinical pancreatology for practicing gastroenterologists and surgeons
• ISBN: 1-119-57014-X; 1-119-57008-5; 1-119-57009-3
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910677212703321
• Lo trovi qui: Univ. Federico II