A study on cholinergic signal transduction pathways involved in short term and long term memory formation in the rat hippocampus : Molecular and cellular alterations underlying memory impairments in animal models of neurodegeneration / / Daniele Lana
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| Autore: |
Lana Daniele
|
| Titolo: |
A study on cholinergic signal transduction pathways involved in short term and long term memory formation in the rat hippocampus : Molecular and cellular alterations underlying memory impairments in animal models of neurodegeneration / / Daniele Lana
|
| Pubblicazione: | Firenze, Italy : , : Firenze University Press, , [2015] |
| ©2015 | |
| Descrizione fisica: | 1 online resource (136 pages) : illustrations |
| Disciplina: | 616.8 |
| Soggetto topico: | Nervous system - Degeneration |
| Sommario/riassunto: | Neurodegenerative processes alter neuronal and glial physiology and cause cognitive and mnemonic impairments. Aim of this PhD thesis is to investigate the involvement of the cholinergic system and the role of mTOR pathway in the mechanisms of memory encoding in the hippocampus and to study the pathophysiological processes at the base of the cognitive impairments in different experimental models of neurodegeneration: in particular normal brain aging, neuroinfiammation and chronic cerebral hypoperfusion. These mechanisms are studied focusing on the morpho-functional alterations in the neuron-astrocytemicroglia triad. |
| Altri titoli varianti: | Study on cholinergic signal transduction pathways involved in short term and long term memory formation in the rat hippocampus |
| Titolo autorizzato: | A study on cholinergic signal transduction pathways involved in short term and long term memory formation in the rat hippocampus |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910571710903321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
Premio Tesi di dottorato.