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Animal Modeling in Cancer
| Animal Modeling in Cancer |
| Autore | Korinek Vladimir |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (273 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
soy
isoflavones mammary tumor prevention rodent models chemical carcinogens transgenic mice Zebrafish Drosophila rats mice NPM-1 FLT3 ITD ETO-1 IDH1/2 neural stem cells brain and nervous system cancers neurogenic niches radiotherapy sparing of neurogenic regions carcinoma consensus molecular subtypes intestine oncogenes signaling cascades tumor suppressors tumorigenesis MPN (myeloproliferative neoplasms) zebrafish iPSCs JAK2 MPL CALR thrombosis ubiquitin–proteasome system cancer mouse model gene inactivation colorectal cancer mouse models microbiota antitumor immunity melanoma mutation genetics animal model swine MeLiM progression spontaneous regression devitalization metaplasia Cdx animal models epigenetics xenotransplantation drug screen pre-clinical cancer model non-mouse models gene editing stem cells solid tumors hematologic malignancies |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557344403321 |
Korinek Vladimir
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Behavioral Impairment in Aquatic Organisms Exposed to Neurotoxic Pollutants
| Behavioral Impairment in Aquatic Organisms Exposed to Neurotoxic Pollutants |
| Autore | Raldúa Demetrio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (152 p.) |
| Soggetto topico |
Research & information: general
Environmental economics Pollution control |
| Soggetto non controllato |
avoidance
behavior habitat selection multi-compartmented systems non-forced exposure repellency natural products fungicides early development teratogenicity zebrafish behaviour oxidative stress ecotoxicology artemia psychotropics behavioural ecotoxicology mixture toxicity neurotoxicity antagonism organophosphate acetylcholinesterase inhibitors GABA risk assessment spontaneous movement activity zebrafish larvae serotonin neurotransmitters modulation copper glyphosate chlorpyrifos early life stages rainbow trout swimming behavior DNA damage development Daphnia magna neurotransmitter pharmaceuticals pharmaceuticals in the environment environmental risk assessment fish mixture toxicology predictive toxicology pollution |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576887403321 |
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Raldúa Demetrio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Biomarkers and Targets in Digestive Organs
| Cancer Biomarkers and Targets in Digestive Organs |
| Autore | Lee Nikki |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (146 p.) |
| Soggetto non controllato |
liver graft injury
HFE neurokinin chemotherapy intestinal tumors therapeutic targets biliary tract carcinoma hepatocellular carcinoma clinical trial cell adhesion molecules colorectal cancer biomarkers phenotypic mosaics gastrointestinal oncology Asian Cancer Research Group (ACRG) biomarker psychosocial support precision therapy pancreatic carcinoma precision medicine Liver transplantation predictive biomarkers CD274 cholecystokinin The Cancer Genome Atlas (TCGA) gastrin pembrolizumab immunotherapy gastrin-releasing peptide stereotactic body radiation therapy immunohistochemistry gastric carcinoma liver transplant CAM invasion assay intragraft gene expression profiles molecular profiling targeted therapy neurotensin intestinal disorder ramucirumab next-generation sequencing colorectal carcinoma tumor progenitor circulating tumor cells gastrointestinal malignancies bombesin trastuzumab somatostatin zebrafish G protein-coupled receptors |
| ISBN | 3-03921-464-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367564003321 |
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Lee Nikki
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular and Molecular Mechanisms of Nephropathic Cystinosis
| Cellular and Molecular Mechanisms of Nephropathic Cystinosis |
| Autore | Levtchenko Elena N |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (230 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
cystinosis
cysteamine bone osteoclast genotype CD34+ hematopoietic stem and progenitor cells gene therapy pre-clinical studies investigational new drug application clinical trial disulfiram mice zebrafish fertility azoospermia hypogonadism histopathology mouse model lysosomal storage disease cell and animal models infantile nephropathic cystinosis bone-muscle wasting fibroblast growth factor 23 osteoclasts sclerostin leptin fractures nephropathic cystinosis hollow fiber membrane 3-dimensional models autophagy macrophages inflammasome proximal tubular cells endocytosis apoptosis chitotriosidase interleukins galectin-3 novel therapies endolysosome epithelial cell differentiation homeostasis lysosomal storage diseases mitochondrial distress kidney proximal tubule programmed cell death central nervous system cortical atrophy arterial spin labelling cystine blood level lysosomal storage disorder history treatment strategies for cystinosis newborn screening clinical course CTNS-pathogenic variants newborn screening for cystinosis kidney progenitors cell model biomarkers cystine kidney therapeutic monitoring |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585941103321 |
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Levtchenko Elena N
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cholinesterase Research
| Cholinesterase Research |
| Autore | Korabecny Jan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (223 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Amaryllidaceae
Narcissus pseudonarcissus cv. Carlton alkaloids carltonine A-C Alzheimer's disease butyrylcholinesterase docking studies organophosphorus nerve agents oxime cholinesterase reactivation ventilation pharmacodynamics blood-brain barrier crossing acetylcholinesterase inhibitors bone healing osseointegration donepezil hemostasis acetylcholinesterase inhibitor dementia zebrafish behavior Alzheimer disease antioxidants butyrylcholinesterase inhibitors molecular modelling nutraceuticals phytochemicals acetylcholinesterase slow-binding inhibition transition state analog organophosphorus osmotic stress neutron scattering molecular dynamics MD simulations fluorene in vitro in silico multi-target directed ligands N-methyl-d-aspartate receptor molecular modeling reactivators reactivation process organophosphates docking hydrolysis molecular recognition catalysis inhibition |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557764703321 |
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Korabecny Jan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Developmental Exposure to Environmental Contaminants
| Developmental Exposure to Environmental Contaminants |
| Autore | Stietz Kimberly Keil |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (256 p.) |
| Soggetto topico |
Medicine
Medical toxicology |
| Soggetto non controllato |
arsenic
synaptic transmission long-term potentiation hippocampus development lower urinary tract bladder inflammation POPs developmental basis of adult disease multigenerational toxicants bronchopulmonary dysplasia therapeutics lung development selective serotonin reuptake inhibitor perinatal mortality neonatal morbidity fluoxetine sertraline endocrine-disrupting chemicals (EDC) Aroclor 1221 (A1221) PCBs vinclozolin social behavior sex differences transgenerational epigenetic endocrine-disrupting chemical (EDC) polychlorinated biphenyl (PCB) mating behavior paced mating ultrasonic vocalization (USV) estradiol triclosan triclocarbon detergents 4-nonylphenol Danio rerio zebrafish environmental toxicity aquatic environment ground water chemicals lower urinary tract dysfunction lower urinary tract symptoms BPH prostate axonal growth developmental neurotoxicity neuronal morphogenesis PBDE reactive oxygen species thyroid hormone pesticides prebiotic intestinal dysbiosis perigestational dysmetabolism risk factor behavior chemical screening literature comparison developmental toxicity negative control positive control rapid testing PFAS PFAS mixtures epigenetics microglia valproic acid primary motor cortex |
| ISBN | 3-0365-5885-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639989003321 |
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Stietz Kimberly Keil
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Disease and the Hippo Pathway: Cellular and Molecular Mechanisms
| Disease and the Hippo Pathway: Cellular and Molecular Mechanisms |
| Autore | Hansen Carsten Gram |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (226 p.) |
| Soggetto non controllato |
STRIPAK
skin cancer Lats2 transcription myofibroblast epigenetic Hippo cancer immunity TAZ Taz TAZ (transcriptional co-activator with PDZ-binding motif) adaptive immunity fibroblasts innate immunity LATS MST (mammalian STE20-like protein kinase) phosphorylation stem cells wound healing signal transduction angiogenesis LATS1/2 EMT protein-protein interactions structure biology Hippo pathway hippo pathway autoimmunity Mps one binder YAP/TAZ GPCR fibrosis MST1/2 YAP (yes-associated protein) YAP Yap protein kinase LATS (large tumor suppressor kinase) peripheral nerve sheath tumor signal cross-talk stem cell skin development STK38 tumorigenesis NDR schwannoma G protein-coupled receptor anti-cancer therapy feedback loops vascular mimicry castration resistance chromatin Hippo signalling ECM MST prostate cancer TEAD cancer zebrafish |
| ISBN | 3-03921-777-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Disease and the Hippo Pathway |
| Record Nr. | UNINA-9910367742003321 |
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Hansen Carsten Gram
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Environmental Analysis of Organic Pollutants
| Environmental Analysis of Organic Pollutants |
| Autore | Liu Wenbin |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (312 p.) |
| Soggetto topico |
Technology: general issues
Chemical engineering |
| Soggetto non controllato |
regulated e-waste recycling
polybrominated diphenyl ethers (PBDEs) heavy metals environmental media vegetable risks cardiovascular diseases (CVDs) heart failure polycyclic aromatic hydrocarbons (PAHs) trace elements serum polyhaloaromatic compounds chemiluminescence analytical method Fenton system hydroxyl radicals bisphenol analogues zebrafish joint toxicity gene expression online monitoring diagnosis PCDD/F incineration feedback control volatile organic compounds (VOCs) reference materials (RMs) quality control (QC) water analysis resin adsorption pore size distribution chemical modification water treatment PCNs spatial distribution congener environmental risk sediment VOCs distribution risk assessment chemical industrial park phthalate dietary intake DEHP DBP DIBP bottled drink PFASs QSAR–ICE–SSD electroplating industry ecological risk assessment PAHs historical trends shallow lake economic parameters sources sediment core gas chromatography-mass spectrometry HBCD EPS XPS POPs tetrabromobisphenol A Xenopus laevis brain development thyroid hormone biphasic concentration-response composting turning frequency ammonia oxidizing bacterial ammonia oxidizing archaeal N fractions ammonia emission screening assay thibz gene multiwell plate biomass combustion CHP plant renewable energies emission organic pollutants bisphenol analogs oxidative stress dechlorane plus maternal blood sequential samples variation correlation bisphenol A emissions polypropylene bottom sediments environmental monitoring Odra River estuary organotin compounds trueness verification |
| ISBN | 3-0365-5316-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619466403321 |
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Liu Wenbin
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fucoidans
| Fucoidans |
| Autore | Jeon You-Jin |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (254 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
fucoidan
low-molecular-weight fucoidan adriamycin nephrotic syndrome psoriasis Traf3ip2 microbiota mucin IgA fucoidans extraction brown algae production bioactivities Sri Lankan algae anticancer sulfated polysaccharide Celluclast sargassum antioxidant Maldives Padina boryana zebrafish apoptosis DR4 mitochondrial pathway cancer metastasis epithelial mesenchymal transition nanoparticles Helicobacter pylori mozuku Cladosiphon okamuranus Tokida urinalysis fucose enzymatic purification age-related macular degeneration VEGF oxidative stress Laminaria digitata Fucus distichus subsp. evanescens Saccharina latissima retinal pigment epithelium ROS Phaeophyta carbohydrate UVB irradiation HaCaT cells sulfated heterosaccharide dopamine neurons apoptosis PI3K-Akt ascorbic acid anti-lung cancer human lung carcinoma A-549 cells hydrogen peroxide Sargassum crassifolium fucoidan from Ascophyllum nodosum postprandial hyperglycemia in vitro and in vivo evaluation SGLT1 chitosan fibroblast growth factor-2 polyelectrolyte multilayer infrared spectroscopy quartz crystal microbalance sulfated polysaccharides natural defenses phenolic metabolism phenylalanine ammonia-lyase |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557704403321 |
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Jeon You-Jin
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Generation of Neurons and Their Integration in Pre-Existing Circuits in the Postnatal Brain: Signalling in Physiological and Regenerative Contexts
| Generation of Neurons and Their Integration in Pre-Existing Circuits in the Postnatal Brain: Signalling in Physiological and Regenerative Contexts |
| Autore | Mira Helena |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (150 p.) |
| Soggetto topico |
Science: general issues
Biology, life sciences |
| Soggetto non controllato |
adult neurogenesis
hippocampus SVZ neural circuits mouse zebrafish |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Generation of Neurons and Their Integration in Pre-Existing Circuits in the Postnatal Brain |
| Record Nr. | UNINA-9910557247703321 |
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Mira Helena
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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