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Lysosomal Storage Disorders: Molecular Basis and Therapeutic Approaches
| Lysosomal Storage Disorders: Molecular Basis and Therapeutic Approaches |
| Autore | Moro Enrico |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (301 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
mucopolysaccharidosis IIIB
quantitative proteomics NAGLU lysosomes Gaucher disease bone involvement enzyme replacement therapy substrate reduction therapy Osteoimmunology RANK/RANKL Osteopontin MIP-1β mucolipidosis II sortilin TGF-beta cathepsin D Fabry disease alpha-galactosidase A endocytosis lysosome IGF2R/M6P clathrin chloroquine lysosomal diseases precision medicine pharmacological chaperones gene therapy Pompe disease lysosomal targeting autophagy muscle satellite cells rhGAA glycogen lysosomal α-glucosidase GAA biomarker Gaucher Disease Wnt/β-catenin Dkk1 Wnt3a iPSC neuronopathy Krabbe disease Twitcher mouse psychosine visual system visual cortex astrogliosis mucopolysaccharidosis type I Hurler syndrome hematopoietic stem cell transplantations animal models experimental therapies axon guidance lysosomal storage disorders neuronal circuit α-galactosidase A A4GALT globotriaosylceramide (Gb3) globotriaosyl-sphingosine (lysoGb3) pharmacological chaperone therapy exosomes endocytic pathways neurodegenerative disease Parkinson disease lysosomal storage disorder viral vectors newborn screening variant interpretation second tier test tandem mass spectrometry lyso-Gb3 dried blood spot GLA gene globotriaosylsphingosine biomarkers |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Lysosomal Storage Disorders |
| Record Nr. | UNINA-9910557545503321 |
Moro Enrico
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neuroanatomy for the XXIst Century
| Neuroanatomy for the XXIst Century |
| Autore | Kathleen S. Rockland |
| Pubbl/distr/stampa | Frontiers Media SA, 2016 |
| Descrizione fisica | 1 electronic resource (199 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
Human neuroanatomy
light-sheet imaging two-photon tomography FIB/SEM fMOST synaptic weights text-mining Polarized light microscopy viral vectors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910220050003321 |
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Kathleen S. Rockland
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| Frontiers Media SA, 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Treatment Strategies for Glioblastoma
| Novel Treatment Strategies for Glioblastoma |
| Autore | Stylli Stanley |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (268 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
glioblastoma
glioma temozolomide radiotherapy immunotherapy novel therapy personalized treatment drug repurposing invasion invadopodia ion channels gene therapy viral vectors brain tumor nanomedicine cancer stem cell targeted therapy brain cancer cell cycle differentiation proliferation RAS SRGAP2 stem cell TP53 glioblastoma multiforme GBM nerve/glial antigen 2 NG2 CK2 CX-4945 migration CRISPR/Cas9 anticancer anti-angiogenesis thyrointegrin αvβ3 PEG triazole tetrac P-bi-TAT P-m-TAT tetrac one-carbon metabolism de novo purine synthesis metabolic reprogramming metabolic treatment vaccine immune checkpoint inhibitors chimeric antigen receptor (CAR) T cells glioblastoma (GB) prolyl-oligopeptidase (POP) vascular endothelial growth factor (VEGF) transforming growth factor-β (TGF-β) angiopoietin (Ang) endothelial nitric oxide synthase (eNOS) newly diagnosed glioblastoma recurrent glioblastoma new trial design drug-inducible gene expression Mardepodect Regorafenib drug targets tumor antigens renin-angiotensin system pluripotent stem cells organoids cancer stem cells cancer stem cell niche tumor microenvironment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557363703321 |
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Stylli Stanley
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant Virus Emergence
| Plant Virus Emergence |
| Autore | Goodin Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (174 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
sugar beet
rhizomania RNAseq virus necrovirus helper virus Aphis gossypii Cucumis melo cucurbit viruses disease progress curve insect trapping logistic model Spearman correlation temporal dynamics Bunyavirale RNA virus emerging virus virus evolution plant virus cophylogeny hallmark genes common bean Phaseolus vulgaris cytorhabdovirus whitefly Bemisia tabaci vector virus transmission ToTV emerging disease prevalence whole-genome sequencing phylogeny tomato torrado virus sGFP plant pathology infectious clone plant-virus interaction pandemics epidemics global disease threat food insecurity crop losses crop failure indigenous viruses introduced crops new encounter spillover developing countries domestication centers sub-Saharan Africa Potyviruses whole genome sequencing epidemiology virus resistance virus host interactions plant viruses viral vectors plant diseases virus spread biopharming vaccines viruses Nicotiana benthamiana COVID-19 plant-based biologics production |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557563403321 |
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Goodin Michael
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Application of Viruses to Biotechnology
| The Application of Viruses to Biotechnology |
| Autore | Varanda Carla |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (296 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
Bacteriophage
Salmonella biocontrol comparative genomics phage diversity grapevine apple latent spherical virus vector virus-induced flowering reduced generation time breeding of grapevine virus elimination Newcastle disease virus reverse genetics vaccines infectious diseases cancer porcine epidemic diarrhea virus VLP chemokines pig vaccine SARS-CoV-2 COVID-19 phages CRISPR viruses prevention diagnosis treatment adeno-associated virus (AAV) vector jaagsiekte sheep retrovirus (JSRV) LTR enhancer transduction viral vaccines cancers COVID-19 vaccines self-replicating RNA vectors DNA-based vaccines RNA-based vaccines plant virus viroid viral vector virus-induced gene silencing (VIGS) CRISPR/Cas9 genome editing carotenoid biosynthesis circular RNA infectious bursal disease virus immunization recombinant Lactococcus lactis variant strain baculovirus insect cells bacmid Tn7 genome stability protein expression chikungunya virus VLPs bioreactor CRISPR/Cas systems viral vectors gene editing plant genome engineering viral resistance adeno-associated virus AAV cancer gene therapy prophage hydrothermal vent Hypnocyclicus thermotrophus lytic cassette Escherichia coli heterologous expression codon optimization codon harmonization expression vectors aspect ratio VNPs TMV PVX CPMV geminivirus theranostics CRISPR-cas9 clodronate macrophage gene therapy gene expression nanotechnology |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557363903321 |
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Varanda Carla
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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