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Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
| Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing |
| Autore | Kim Jong Heon |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (282 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
3-phenyl-1H-indazole
Acanthamoeba Acanthamoeba keratitis acetylsalicylic acid (ASA, aspirin) all-trans retinoic acid anticandidal activity antifungal antifungal drugs antifungals Aspergillus spp azole azoles beta-glucan biological synthesis candida Candida candida albicans Candida auris Candida spp candidosis canesten CAP64 capsule cell integrity cell lysis cell separation cell wall clotrimazole Cryptococcus cyst cytokinesis dermatophytes drug drug delivery systems drug design drug discovery drug repurposing drug targets echinocandin drugs echinocandin resistance echinocandins emerging fungi Felis catus fission yeast Fks resistance hot spots free-living ameba fungi Galleria mellonella model host-directed drug therapy hydrazones indazole invasive aspergillosis treatment invasive fungal infections isavuconazonium sulfate Malassezia spp marine membrane potential (ΔΨM) microbiology multidrug resistance mycology myconanotechnology mycosis n/a nanoparticles natural products new targets onychomycosis photodynamic treatment photosensitiser polycations polyenes pyrazole quinones repositioning resistance retinoids septation sporotrichosis synergy therapeutic alternatives ultrastructure vaginal health vaginitis viral infections vulvovaginal yeast infection yeasts zoonoses β(1,3)-D-glucan synthase |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Advances in Antifungal Development |
| Record Nr. | UNINA-9910585935503321 |
Kim Jong Heon
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Animal model studies on viral infections [[electronic resource] /] / Topic editors: Akio Adachi and Tomoyuki Miura
| Animal model studies on viral infections [[electronic resource] /] / Topic editors: Akio Adachi and Tomoyuki Miura |
| Autore | Tomoyuki Miura |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 online resource (173 pages) : illustrations; digital, PDF file(s) |
| Collana |
Frontiers research topics
Frontiers in microbiology |
| Soggetto topico |
Microbiology
Virus diseases - Pathogenesis Virology - Research |
| Soggetto non controllato |
viral replication
animal models viral infections anti-viral strategies viral pathogenicity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Animal model studies on viral infections --Animal models for human Herpesvirus 6 infection --Animal models for Ebola and Marburg virus infections --Hepatitis C virus infection and related liver disease: the quest for the best animal model --Can non-human primates serve as models for investigating Dengue disease pathogenesis? --A transgenic mouse model of human T cell Leukemia virus type-1 associated diseases --Mechanisms of pathogenesis induced by bovine leukemia virus as a model for human T-cell leukemia virus --Macaques as model hosts for studies of HIV-1 infection --Macaque-tropic Human Immunodeficiency Virus type 1: breaking out of the host restriction factors --Genetic similarity of circulating and small intestinal virus at the end stage of acute pathogenic Simian-Human Immunodeficiency Virus infection --A novel but simple method for generation of human dendritic cells from unfractionated peripheral blood mononuclear cells within 2 days: its application for induction of HIV-1-reactive CD4⁺ T cells in the hu-PBL SCID mice --Growth potentials of CCR5-Tropic/CXCR4-Tropic HIV-1mt clones in macaque cells --Sensitive detection of measles virus infection in the blood and tissues of humanized mouse by one-step quantitative RT-PCR --Quantification of viral infection dynamics in animal experiments --Transgenic expression of the human LEDGF/p75 gene relieves the species barrier against HIV-1 infection in mouse cells --Increased infectivity in human cells and resistant to antibody-mediated neutralization by truncation of the SIV gp41 cytoplasmic tail --Natural infection of murine novovirus in conventional and specific pathogen free laboratory mice --HPV18 E1̂ˆ̂E4 is assembled into aggresome-like compartment and involved in sequestration of viral oncoproteins. |
| Record Nr. | UNINA-9910136287303321 |
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Tomoyuki Miura
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| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Impaired Mitochondrial Bioenergetics under Pathological Conditions
| Impaired Mitochondrial Bioenergetics under Pathological Conditions |
| Autore | Lenaz Giorgio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (460 p.) |
| Soggetto topico |
Biochemistry
Biology, life sciences Research & information: general |
| Soggetto non controllato |
aging
aging heart assembly factor ATP synthase ATP synthase/hydrolase atypical myopathy Barth syndrome Bcl-2 family bioenergetics C cancer cardiolipin cardiomyopathy cell culture cell signaling cellular bioenergetics cellular signaling complex I assembly complex I deficiency complex I structure complex III COVID-19 cristae cytochrome b diabetes Dilated Cardiomyopathy with Ataxia electron transport chain energy metabolism entorhinal cortex equine primary myoblasts exercise fatty acid oxidation fibroblasts frozen tissue G mutation glucagon heart failure high-resolution respirometry human disease immune system influenza innate immune response insulin Leigh syndrome leukocytes lipoxidation-derived damage m.3243A> m.8909T> mammalian complex I mathematical model MAVS MDA5 metabolic disease mitochondria mitochondrial disease mitochondrial diseases mitochondrial DNA mitochondrial dynamic mitochondrial dynamics mitochondrial dysfunction mitochondrial permeability transition pore mitochondrial proteostasis MT-ATP6 MTCYB mutations n/a NADH dehydrogenase nephropathy neurodegeneration oleate oxidative damage oxidative phosphorylation oxidative stress oxygen consumption palmitate pancreatic endocrine cells pet mutants platelets programmed cell death protein import respiratory chain respiratory complex assembly respiratory complexes respiratory supercomplexes respirometry RIG-I ROS RSV Saccharomyces cerevisiae SARS CoV-2 Sengers syndrome skeletal muscle supercomplexes supernumerary subunits toxicity assays viral infections yeast |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585934503321 |
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Lenaz Giorgio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Medical Nutrition Therapy in Critically Ill and COVID-19 Patients
| Medical Nutrition Therapy in Critically Ill and COVID-19 Patients |
| Autore | Karayiannis Dimitrios T |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (172 p.) |
| Soggetto topico |
Biology, life sciences
Cultural studies: food and society Research and information: general |
| Soggetto non controllato |
acute respiratory distress syndrome
ARDS cardiovascular risk factors cohort study coronavirus disease 2019 COVID-19 critical care critical illness disease dysphagia energy achievement rate energy target enteral nutrition flexible endoscopic evaluation of swallowing gastric emptying gastric residual volume guidelines adherence high nutritional risk histamine hyperglycemia immunonutrition Indonesia inflammation intensive care intensive care patient intensive care unit ketogenic diet length of stay lockdown long COVID-19 malnutrition modified nutrition risk in the critically ill mortality muscle strength n/a neurology nutrition care nutritional status obesity osteocalcin pandemic parenteral nutrition performance status pneumonia prolonged prone positioning respiratory failure retinoic acid retinol SARS-CoV-2 SARS-CoV-2 virus self-evaluation swallowing viral infections vitamin A Vitamin D VLCKD |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585939703321 |
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Karayiannis Dimitrios T
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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