Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics
| Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics |
| Autore | Tutone Marco |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (387 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
3D-QSAR
pharmacophore modeling ligand-based model HDACs isoform-selective histone deacetylase inhibitors aminophenylbenzamide hERG toxicity drug discovery fingerprints machine learning deep learning gene expression signature drug repositioning approaches RNA expression regulation high-throughput virtual screening dual-target lead discovery neurodegenerative disorders Alzheimer's disease dual mode of action multi-modal nicotinic acetylcholine receptor acetylcholinesterase molecular docking methotrexate drug resistance human dihydrofolate reductase virtual screening molecular dynamics simulation epitope binning epitope mapping epitope prediction antibody:antigen interactions protein docking glycoprotein D (gD) herpes simplex virus fusion proteins Src inhibitors pharmacophore model molecular dynamics simulations in silico COX-2 inhibitors molecular modeling sodium-glucose co-transporters 2 FimH uropathogenic bacteria urinary tract infections diabetes drug-resistance mutations HIV-2 protease structural characterization induced structural deformations SARS-CoV-2 COVID-19 multiprotein inhibiting natural compounds MD simulation 3CL-Pro antivirals docking simulations drug repurposing consensus models binding space isomeric space MRP4 SNPs variants protein threading modeling molecular dynamics binding site hTSPO PK11195 cholesterol homology modeling molecular dynamics (MD) simulation carbon nanotubes Stone-Wales defects haeckelite defects doxorubicin encapsulation drug delivery system binding free energies noncovalent interactions main protease mutants inhibitors PF-00835231 Mycobacterium tuberculosis tuberculosis proteasome natural compounds multiscale multitargeting polypharmacology computational biology drug repositioning structural bioinformatics proteomic signature skin aging oxidative stress aging progression mechanism genome-wide genetic and epigenetic network (GWGEN) systems medicine design multiple-molecule drug immunoproteasome non-covalent inhibitors MD binding metadynamics induced-fit docking |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Computational Approaches |
| Record Nr. | UNINA-9910557519403321 |
Tutone Marco
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Feature Paper in Antibiotics for 2019
| Feature Paper in Antibiotics for 2019 |
| Autore | Lipman Jeffrey |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Antimicrobial resistance
antibiotics antimicrobial stewardship inappropriate prescribing days of therapy Start Smart then Focus piperine piperlongumine antibacterial antifungal synergy non-target feed florfenicol thiamfenicol chloramfenicol HPLC-MS/MS validation swine out-of-hours care primary care quality of care quality indicators practitioners cooperative antibiotic stewardship fluoroquinolones guidelines urinary tract infections quality improvement general practitioners guideline health inequalities health equity assessment tool public health Enterobacteriaceae carbapenem-resistant CRE antibiotic resistance antimicrobials bacteriophages biofilms novel antimicrobials Antibiotics resistance broad-spectrum agents hospital epidemiology antibiotic utilization infection control infection prevention Pseudomonas aeruginosa Acinetobacter baumannii extended-spectrum beta-lactamases carbapenem-resistant Enterobacteriaceae methicillin-resistant Staphylococcus aureus clinical trials infectious disease phage therapy silver complexes camphorimine anti-Candida activity antifungals antibacterials efflux inhibitors efflux pumps erm(41) mutations mycobacteria verapamil actinomycetes bioactivity polyketides polyketide synthases biosynthesis antimicrobial resistance economic evaluation cost-utility analysis cost-effectiveness analysis policy analysis One Health Singapore antibiotic prescribing implementation behavior change stakeholder consultation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557689603321 |
|
Lipman Jeffrey
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Flavonoids and Their Disease Prevention and Treatment Potential
| Flavonoids and Their Disease Prevention and Treatment Potential |
| Autore | Rupasinghe H.P. Vasantha |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (346 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
luteolin
apigenin bacoside A bacopaside I vasorelaxation isorhamnetin flavonoid bacterial sepsis toll-like receptor 4 inflammation citrus flavonoids neohesperidin anti-aging activity chronological lifespan synergistic effect clinical trials natural products hyperalgesia allodynia analgesia hypersensitivity cytokines NF-kB defatted pitaya seed extraction phenolic content flavonoid content antioxidant activity response surface methodology flavonoids aglycons glycosides IL-1β TNF-α IL-6 IL-8 pro-inflammatory cytokines Acer okamotoanum afzelin isoquercitrin obesity quercitrin aspirin cancer prevention hydroxybenzoic acids cell cycle CDKs colorectal cancer infectious diseases amoebiasis Mexican oregano bioguided isolation antiprotozoal agents flavones cancer microbiome molecular mechanisms gene and protein regulatory networks macrophages NF-κB IKKβ, inflammatory cytokines apoptosis foods for health tangeretin cancer stem cells Stat3 citrus CD44+/CD24− phytochemicals flavonoids and their derivatives phytomedicine COVID-19 SARS-COV-2 smart nanoparticles non-flavonoids membrane PUFAs profile cell morphology human colon cancer cells cranberry urinary tract infections UTIs uropathogenic Escherichia coli UPEC flavan-3-ols A-type proanthocyanidins phenolic metabolites antiadhesive activity probiotics anthocyanin tobacco-specific nitrosamine carcinogenesis cell proliferation cancer chemoprevention lung cancer chalcones DNA damage anticancer activity canine cancer cell lines angiogenesis in-vivo angiogenesis CAM assay SAR cognition passive avoidance test memory extinction mice microglia neuroprotection black rice cyanidin-3-O-glucoside wood sterols dyslipidemia CVD |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557505903321 |
|
Rupasinghe H.P. Vasantha
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Hospital Acquired Infections, Multidrug Resistant (MDR) Bacteria, Alternative Approaches to Antibiotic Therapy
| Hospital Acquired Infections, Multidrug Resistant (MDR) Bacteria, Alternative Approaches to Antibiotic Therapy |
| Autore | Bostik Pavel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (206 p.) |
| Soggetto topico |
Medicine
Epidemiology & medical statistics |
| Soggetto non controllato |
VRE
GIT hemato-oncological patients clonality antibiotic stewardship resistance consumption of antibiotics clonal spread Enterococcus faecium Enterococcus faecalis linezolid resistance 23S rRNA optrA carbapenem-resistant Klebsiella pneumoniae carbapenem-resistant Acinetobacter baumannii N-acetylcysteine septic shock critically ill patients newborn infection bacteria antibiotic therapy hops C. difficile rat model Staphylococcus aureus MRSA spa typing MLST SCCmec typing clonal analysis epidemiology cancer patients duration of treatment colistin propensity score analysis multidrug-resistant Acinetobacter baumannii urinary tract infections UTIs MDR Escherichia coli Klebsiella uropathogens AMR antibiotic resistance ESBL-producing Klebsiella pneumoniae urinary tract infection clinical impact economic impact ventilator-associated pneumonia Klebsiella spp Escherichia spp pulsed-field gel electrophoresis (PFGE) endogenous infection methicillin-resistant porcine model methicillin-resistant Staphylococcus aureus (MRSA) long term care facilities (LTCF) multidrug resistance (MDR) enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR) ESBL PCR primer antimicrobial resistance infection prevention and control antimicrobial stewardship hospital cluster analysis principal component analysis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Hospital Acquired Infections, Multidrug Resistant |
| Record Nr. | UNINA-9910580212703321 |
|
Bostik Pavel
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
New Insights on Biofilm Antimicrobial Strategies
| New Insights on Biofilm Antimicrobial Strategies |
| Autore | Melo Luís |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (264 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
antibiofilm
antimicrobial agent bacteria fungi polymicrobial biofilm microalga free fatty acids encapsulation biofilm chronic wounds host response S100A8/A9 dental plaque quorum sensing microbial resistance bacterial adhesion blocking effect hydrodynamics parallel plate flow cell carbon nanotubes poly(dimethylsiloxane) adhesion Escherichia coli Biofilm Public Engagement Outreach Control Strategies Oral Biofilm TiO2 nanofibers electrospinning biofilm prevention and control multidrug-resistant bacteria biomedical application biofilms biofilm inhibition dental implants peri-implantitis polyether-ether-ketone Pseudomonas aeruginosa Candida albicans mixed-species biofilm analysis flow cytometry bacteriophage therapy prosthesis related infections hardware infections left ventricular assist devices Acinetobacter baumannii antibiotic resistance antibiotic tolerance persister intraspecies community EPS matrix peptide nucleic acid-fluorescence in situ hybridization urinary tract infections catheter-associated urinary tract infections confocal laser scanning microscopy recalcitrance biofilm control Klebsiella pneumoniae KPC and OXA-48-like carbapenemases Galleria mellonella infection model linear oligoethyleneimine hydrochloride bacteriophage endotracheal tube |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557721803321 |
|
Melo Luís
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pediatric and Adolescent Nephrology Facing the Future: Diagnostic Advances and Prognostic Biomarkers in Everyday Practice
| Pediatric and Adolescent Nephrology Facing the Future: Diagnostic Advances and Prognostic Biomarkers in Everyday Practice |
| Autore | Taranta-Janusz Katarzyna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (304 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
chronic kidney disease
cytokines solitary functioning kidney tumor necrosis factor-like weak inducer of apoptosis netrin-1 renal tubular damage premature newborns overactive bladder urinary microbiome children adolescents cystatin C galectin-3 periostin primary hypertension arterial damage blood pressure neurogenic bladder myelomeningocele markers furosemide stress test hyperfiltration [IGFBP-7] × [TIMP-2] NGAL renal angina index renal functional reserve tubular damage tubuloglomerular feedback neurotrophins transcutaneous electrical nerve stimulation hemopexin nephrotic syndrome HNF1B hyperuricemia PTH renal function uric acid FEUA sclerostin obesity childhood dental caries gingivitis kidney injury glomerulopathy glomerular injury alpha-1 acid glycoprotein urinary mRNA expression of podocyte-associated proteins cathepsin B premature neonates immaturity NT-proBNP cardiovascular disease common carotid artery intima-media thickness bone morphogenetic protein (BMP)-2 bone morphogenetic protein (BMP)-6 extracellular matrix metalloproteinases inducer (EMMPRIN) macrophage migration inhibitory factor (MIF) tubular functional reserve cytokeratin-18 endoglin transforming growth factor-β1 renal fibrosis congenital obstructive nephropathy diabetic kidney disease vascular endothelial markers eGFR adenine nucleotide metabolites chronic renal failure antibiotic resistance Escherichia coli inflammatory markers urinary tract infection B2M cancer CCS CKD nephropathies renal toxicity voiding cystography infection urinary tract IgA nephropathy IgA vasculitis with nephritis vanin-1 biomarker urinary tract infections artificial intelligence machine learning medical decision support system |
| ISBN | 3-0365-5974-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Pediatric and Adolescent Nephrology Facing the Future |
| Record Nr. | UNINA-9910639989903321 |
|
Taranta-Janusz Katarzyna
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||