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Hallmarks of Parkinson’s Disease
| Hallmarks of Parkinson’s Disease |
| Autore | Alves Da Costa Cristine |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (124 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
Parkinson’s disease
unfolded protein response reticulum endoplasmic genetics alpha-synuclein prion-like spreading cell-to-cell transfer neurodegeneration mitochondrial dysfunction PINK1 neurons astrocytes microglia α-synuclein exocytosis lipids membranes Parkinson disease SNARE complex synapse vesicle fusion therapeutic target protein quality control mitochondrial quality control ubiquitin alpha-syn mitophagy Parkin mito-Keima mito-QC mito-SRAI |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069503321 |
Alves Da Costa Cristine
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Immunophenotyping in Autoimmune Diseases and Cancer
| Immunophenotyping in Autoimmune Diseases and Cancer |
| Autore | Szebeni Gábor J |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (170 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
accidental cell death
Activating transcription factor 6 (ATF6) B cells breast cancer cancer cancer immunology CD180 CD8+CD28− T cells cell therapy chimeric antigen receptor choriocarcinoma citrate synthase CpG dcSSc DDR DNA topoisomerase I flow cytometry galectin galectin 1 gestational trophoblastic disease glioblastoma Glucose-regulated protein 78 (GRP78) glycosylation glycosylation enzymes hydatidiform mole IgM IL-10 IL-6 immune cells immunohistochemistry immunophenotyping immunotherapy Inositol-requiring enzyme 1 (IRE1) lectin binding macrophage malignant glioma metastatic breast cancer myeloid-derived suppressor cells natural autoantibodies neuroendocrine carcinoma neuroendocrine neoplasia neuroendocrine tumor non-switched B cells oncosis parthanatos PKR-like endoplasmic reticulum kinase (PERK) placental-specific gene RP105 sialylation single cell mass cytometry syntaxin 1 systemic lupus erythematosus systemic sclerosis systems biology T cell T cells TLR trastuzumab trophoblast differentiation tumor microenvironment unfolded protein response |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557289203321 |
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Szebeni Gábor J
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Therapies for Inherited Retinal Diseases
| Molecular Therapies for Inherited Retinal Diseases |
| Autore | Collin Rob W.J |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (262 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
AAV
ABCA4 adeno-associated viral adeno-associated virus (AAV) allele-specific knockdown antisense oligonucleotides AON-mediated exon skipping apical polarity apoptosis ARPE-19 cells autophagy autosomal dominant bipolar cells CEP290 chaperones chaperonins choroideremia Cilia elongation clathrin-coated vesicles clinical trials clustered regularly interspaced short palindromic repeats (CRISPR) compound therapies cones crumbs complex cyclic GMP DNA therapies DNA-wrapped gold nanoparticles drug delivery systems dual AAV endosomal trafficking Enhanced S-Cone Syndrome (ESCS) fetal retina Flanders founder c.4723A > G56R gapmer antisense oligonucleotides gene augmentation gene therapy gold nanoparticles heat shock response homology-directed repair (HDR) induced pluripotent stem cell (iPSC) inherited retinal disease inherited retinal diseases iPSC-derived photoreceptor precursor cells IRD Leber congenital amaurosis Leber congenital amaurosis and allied retinal ciliopathies microRNA Müller glia n/a necrosis nonprofit NR2E3 PAR complex patient registry photoreceptors protein degradation protein folding protein trafficking putative dominant negative effect REP1 retina retinal degeneration retinal inherited disorders retinal organoids retinal pigment epithelium retinitis pigmentosa Retinitis Pigmentosa (RP) Retinitis Pigmentosa GTPase Regulator retinogenesis RNA therapies RNA therapy rods RPE65 splicing modulation spontaneous nonsense correction Stargardt disease T nonsense mutation therapy translational translational medicine treatment unfolded protein response Usher syndrome |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674051103321 |
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Collin Rob W.J
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural Products and Neuroprotection
| Natural Products and Neuroprotection |
| Autore | Angeloni Cristina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (338 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
5-(3,5-dihydroxyphenyl)-γ-valerolactone
algae Alzheimer's disease animal studies antioxidant ascaroside pheromone auraptene autophagy B-cell lymphoma 2 beneficence bioactive compound bioavailability blood-brain barrier C. elegans calcium catechin cell death Centella asiatica chaperones Chionanthus retusus clinical trial cognition cognitive dysfunction curcumin cyclic AMP dauer depression dopamine neuron dynamics epigallocatechin gallate ethics flavonoid flower free radicals glycogen synthase kinase 3 green tea heme oxygenase hippocampus HO-1 hormesis human studies in vitro studies inflammation learning Lippia citriodora medical liability memory microbiota mitochondria mitochondrial dysfunction mitophagy Multiple Sclerosis n/a natural compound natural compounds natural extract natural products neurodegeneration neurodegenerative disease neurodegenerative diseases neuroinflammation neuronal signaling neuroprotection NO nonmaleficence nutraceuticals oxidative injury oxidative stress Parkinson's disease Parkinson's disease (PD) patients' autonomy protein aggregation protein poshophatase 2 proteostasis relaxation safety profile seaweeds sexual behavior stress response survival signals symptom synapse loss tau protein terpenes, rotenone thymol type 2 diabetes ubiquitin-proteasome ubiquitin‒proteasome system (UPS) unfolded protein response vascular damage VEE Vitamin D Vs β-amyloid peptide |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557705603321 |
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Angeloni Cristina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases
| Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases |
| Autore | Kwok Hang Fai |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (180 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
AKT
amphibian Bowman-Birk inhibitor amyloidogenesis anionic lipids anti-inflammation anticancer therapy anticancer therapy/cancer treatment antifungal antioxidant apoptosis Asteraceae Astragalus membranaceus Bcl-2 family proteins binding affinity branched-chain fatty acids cell cycle arrest colorectal cancer Conidiobolus heterosporus COX-2 DAPK1 docetaxel drug delivery system drug design endoplasmic reticulum F23R variant fatty acid oxidation fibroblasts fucoidan G-protein activation gingiva hepatocyte hIAPP iNOS insulin insulin granules kynurenines lignan lipid metabolism lung cancer molecular cloning molecular docking n/a natural-based compound NO orientin PDX-1 peptides peroxisome proliferator-activated receptor α Petasites japonicus PGE2 pharmacophore PI3K PLGA pomegranate post-translational modification PPARγ protease inhibitor protein degradation punicalagin SENP STAT3 SUMO survivin tannins Tat peptide unfolded protein response wound healing β-cell cytotoxicity β-sheet transitions μ-opioid receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607403321 |
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Kwok Hang Fai
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Protein Quality Controlling Systems in Plant Responses to Environmental Stresses
| Protein Quality Controlling Systems in Plant Responses to Environmental Stresses |
| Autore | Yule Liu |
| Pubbl/distr/stampa | Frontiers Media SA, 2018 |
| Descrizione fisica | 1 online resource (214 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Botany & plant sciences |
| Soggetto non controllato |
autophagy
environmental stress heat shock proteins plant proteasome unfolded protein response |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346745403321 |
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Yule Liu
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| Frontiers Media SA, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Retina in Health and Disease
| The Retina in Health and Disease |
| Autore | Ptito Maurice |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (465 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
3,5-DHBA
Ac2-26 African-American age-related macular degeneration AII amacrine cell altricial bird species Alzheimer's disease AMD amyloid angiogenesis angiography antioxidants apoptosis arterioles astrocytes ATP atypical cannabinoid receptors autophagy axon betulinic acid bioenergetics biomarker black catalase CD4+CD25+ cellular senescence Charles Bonnet syndrome clinical trials cognitive decline complement cascade complication development diabetes diabetes mellitus diabetic retinopathy dLGN Drp1 early detection eccentricity EEG electron microscopy electroretinography endoplasmic reticulum epidermal growth factor exendin-4 experimental models eye eye inflammation fingolimod FPR receptor functional analysis gap junction germ-free mice GFAP glucagon-like peptide-1 GPR81 growth cone GRP78 gut microbiome gut-retina axis HCAR1 HDAC high-fat diet histone deacetylase hyperglycemia hypoxia immunodeficient RCS rat immunohistochemistry inflammation inflammatory mediators iPSC iPSC-RPE ischemia-reperfusion injury kallikrein-kinin system kinin receptors lactate LED screen light damage lipopolysaccharide macroglia mesenchymal stem cells metabolism microglia microglia morphotype microvascular microvascular complications and dysfunction mitochondria monkeys motor protein Müller cells multiple sclerosis myosin 1C n/a natural bioactive extracts neurod neurodegeneration neuroprotection neurovascular unit Notch ON/OFF asymmetry optic nerve crush optic neuritis optical coherence tomography optical filter osteopontin outer segments oxidative stress parvalbumin photoreceptor photoreceptors precocial bird species progenitor cell programmed cell death Prox1 reactive oxygen species regeneration remodeling respiration resting state retina retinal degeneration retinal degenerative diseases retinal detachment retinal fluorescence imaging retinal ganglion cells retinal glial cell retinal inflammation retinal light injury retinal microglia retinal pigment epithelium retinal protection retinal transplantation retinal vessels retinogenesis retinopathy rhodopsin RNA sequencing senescence-associated galactosidase activity signal transducer and activator of transcription 3 spinal cord injury stem cell therapy stress response systemic disease trichostatin A (TSA) typical cannabinoid receptors ultrathin parylene unfolded protein response vascular endothelial growth factor (VEGF) vascularization visual function visual hallucination visual system zebrafish |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557336603321 |
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Ptito Maurice
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ubiquitin and Autophagy
| Ubiquitin and Autophagy |
| Autore | Nazarko Taras Y |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (294 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
aggrephagy
APP ATG12~5/16 complex Atg8 autophagy autophagy initiation autophagy-lysosome pathway BECN1 C. elegans cargo receptors crosstalk Cx43 degradation Dictyostelium endosome ER-phagy FIP200 GABARAP gap junction globoid cell leukodystrophy islet LC3 leukodystrophies lipophagy LIR motif lysophagy lysosome MAPLC3 mitophagy n/a neurodegenerative diseases NFAT5 nucleophagy p62 phagocytosis pinocytosis plants proteasome PSMD14 psychosine retrograde retromer SAR selective autophagy sorting nexins the ubiquitin-proteasome system tissue specificity toll-like receptor 4 TRAF6 trafficking ubiquitin ubiquitin-like protein ubiquitin-proteasome system ubiquitination UBL unfolded protein response UPR UPS xenophagy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339503321 |
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Nazarko Taras Y
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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