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Advances in the Diagnosis and Treatment of Thyroid Carcinoma
| Advances in the Diagnosis and Treatment of Thyroid Carcinoma |
| Autore | Medas Fabio |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (286 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
thyroid carcinoma
prophylactic central lymph node dissection lymph node metastases RET medullary thyroid carcinoma clinical management variants of uncertain significance differentiated thyroid cancer papillary thyroid cancer minimal extrathyroidal extension radioactive iodine therapy prognosis TNM histology multifocality lymph node metastasis vascular invasion autoimmune thyroid diseases radioiodine refractory Lenvatinib 18F-FDG-PET/CT cost-benefit analysis economics medical thyroid neoplasms radiomics ultrasound magnetic resonance imaging computer tomography prediction classification angiogenic microenvironment prognostic factors antiangiogenic therapy therapeutic target tumor microenvironment tumor behavior proliferation pathways cell cycle control pathways angiogenesis process thyroid cancer Gal-3 expression NIFTP EFVPTC lymphocytic thyroiditis (LT) immunohistochemical (IHC) analysis molecular imaging theranostics companion diagnostics immunoPET anaplastic thyroid cancer poorly thyroid cancer genetic landscape genetically guided therapy fluorodeoxyglucose F18 (18F-FDG) positron emission tomography (PET) magnetic resonance imaging (MRI) recurrence neoplasm metastasis thyroid surgery hypoparathyroidism fluorescence-guided surgery near-infrared autofluorescence PRKAR1A PKA Carney complex cAMP bone metastasis metastasectomy stereotactic radiosurgery ultrasound imaging thyroid nodule fine-needle aspiration papillary thyroid carcinoma lobectomy operative extent CONUT score tyrosine kinase inhibitors |
| ISBN | 3-0365-5333-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619464303321 |
Medas Fabio
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in the Treatment of Renal Cell Carcinoma
| Advances in the Treatment of Renal Cell Carcinoma |
| Autore | Reynolds Paul |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (221 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
renal cell carcinoma
autophagy hydroxychloroquine chloroquine ROC-325 cysteine cathepsins cysteine cathepsin inhibitors lysosome renal cancer metastatic renal cell carcinoma immune-based combination therapies network meta-analysis PD-L1 predictive biomarker treatment TKIs mRCC biomarkers soluble factors immunotherapy renal cell carcinoma (RCC) sunitib resistance artesunate (ART) Traditional Chinese Medicine (TCM) growth inhibition ferroptosis reactive oxygen species (ROS) clear cell renal cell carcinoma ccRCC RCC kidney cancer evolution evolutionary trajectory metastatic second line therapy renal cell cancer immune checkpoint inhibitors tyrosine kinase inhibitors individualization genomic signature transcriptomic analysis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557615503321 |
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Reynolds Paul
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Derivatization in Analytical Chemistry
| Derivatization in Analytical Chemistry |
| Autore | Tzanavaras Paraskevas D |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (210 p.) |
| Soggetto topico |
Research & information: general
Chemistry Analytical chemistry |
| Soggetto non controllato |
tyrosine kinase inhibitors
chloranilic acid charge-transfer reaction 96-microwell spectrophotometric assay high-throughput pharmaceutical analysis biogenic amines Lycium barbarum L. HPLC derivatization amino acids esterification GC–MS pentafluoropropionic anhydride stability toluene pigment linseed oil derivatisation quantification P/S ratio A/P ratio ∑D GC-MS ureide BSTFA creatine creatinine silylation TMS validation low-molecular-weight thiols human serum albumin α-lipoic acid blood plasma monobromobimane reduction sodium borohydride high-performance liquid chromatography fluorescence detection taurine glutamine clams high-resolution mass spectrometry nerve agents methylation chemical warfare agents sarin Novichoks 2-naphthalenethiol sulforaphane HPLC-UV/Vis pharmacokinetics acetonitrile-related adducts acetylenic lipids double and triple bond localization in-source derivatization mass spectrometry acetazolamide carbonic anhydrase enhancement inhibition pentafluorobenzyl bromide chiral metabolomics rice water d-amino acids enantiomer separation dimethyl labeling homocysteine thiolactone homocysteine zone fluidics o-phthalaldehyde fluorosurfactant-modified gold nanoparticles |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576885703321 |
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Tzanavaras Paraskevas D
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug-Drug Interactions
| Drug-Drug Interactions |
| Autore | Kim Dong Hyun |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (242 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
tadalafil
ticagrelor drug-drug interaction pharmacokinetics plasma concentration CYP3A4 Loxoprofen CYP3A Dexamethasone Ketoconazole CYP2D6 O-desmethyltramadol physiologically-based pharmacokinetics tramadol (‒)-sophoranone CYP2C9 potent inhibition in vitro in vivo drug interaction low permeability high plasma protein binding biflavonoid cytochrome P450 drug interactions selamariscina A uridine 5′-diphosphoglucuronosyl transferase tissue-specific systemic exposure P-glycoprotein (P-gp) organic anion transporting polypeptide 1A2 (OATP1A2) Rumex acetosa fexofenadine chronic kidney disease drug–drug interactions polypharmacy adverse drug reactions Lexicomp subset analysis signal detection algorithms spontaneous reporting systems mechanism-based inhibition competitive inhibition non-competitive inhibition substrate inhibitor cytochromes P450 OATP1B1 OATP1B3 tyrosine kinase inhibitors drug-drug interactions migraine lasmiditan gepants monoclonal antibodies CYP1A1 CYP1A2 drug–drug interaction expression metabolism regulation drug transporter ubiquitination ixazomib DDI computational prediction in silico QSAR drug metabolism ADME CYP metabolic DDI P450 1A2 2B6 2C19 2C8 2C9 2D6 3A4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557666403321 |
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Kim Dong Hyun
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dynamical Models of Biology and Medicine
| Dynamical Models of Biology and Medicine |
| Autore | Kuang Yang |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (294 p.) |
| Soggetto non controllato |
predator-prey model
uncertainty quantification identification of DNA-binding proteins chemostat numerical characterization differential equations uniform persistence spotting 2-combination wildfire chronic myeloid leukemia combination therapy liquid-solid-porous media seepage coupling dynamic model obesity epidermis articular cartilage androgen deprivation therapy quorum sensing mechano-electrochemical model bifurcations bacterial competition global stability cartilage degeneration flocculation dynamical system transport equations bootstrapping stationary distribution algae growth models hemodynamic model delay Raphidocelis subcapitata cartilage loading Daphnia magna cell-based vector switched harvest hepatitis B rich dynamics spotting distribution asymptotic theory tyrosine kinase inhibitors phylogenetic analysis immune response microcirculation load graphical representation intraguild predation numerical simulation bacterial inflammation data fitting immunomodulatory therapies drug therapy delay differential equations (DDE) global asymptotic stability model comparison tests optimal control generalized pseudo amino acid composition random perturbations limit cycle prostate cancer mathematical model mathematical modeling persistence equilibrium points |
| ISBN | 3-03921-218-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367757303321 |
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Kuang Yang
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Immunotherapy, Tumor Microenvironment and Survival Signaling
| Immunotherapy, Tumor Microenvironment and Survival Signaling |
| Autore | Golubovskaya Vita |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (376 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
Autophagy
colorectal cancer immunotherapy tumor stroma tumor microenvironment immune checkpoint inhibitors chemotherapy tyrosine kinase inhibitors angiogenesis check point inhibitors programmed cell death protein 1 programmed cell death 1 ligand 1 cardiotoxicity lung metastasis CAR-T hypoxia tumor microenvironment CD19 BCMA cancer melanoma immune escape antigen loss chimeric antigen receptor electroporation lentivirus lentiviral transduction macrophages leukemia cells lytic peptides targeted therapy dendritic cells pathogenesis risk factors breast cancer resistance checkpoint targeted treatment personalized medicine pediatric solid tumors chimeric antigen receptors cancer vaccines oncolytic viral therapy immunomodulation DCLK1 tumor stem cells clonogenicity mitochondria mitochondrial transfer tunneling nanotubes triple-negative breast cancer immune checkpoint inhibitor combination therapy cancer nanomedicine tumor antigens cancer metabolism cancer immunotherapy nanoparticles immunotherapeutic agent immunomodulators tuft cells cancer stem cells immunotherapies myeloid-derived suppressor cells regulatory T cells crosstalk tumor immune evasion cell-cell contact β2 integrins CD18 CD11 CAR-T cells CD37 cell therapy tumor antigen lymphoma CAR macrophage CAR T cell solid tumors immunometabolism miRNA immunogenic cell death |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580205403321 |
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Golubovskaya Vita
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural Compounds as New Cancer Treatments
| Natural Compounds as New Cancer Treatments |
| Autore | Barrajon Enrique |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (128 p.) |
| Soggetto non controllato |
microbiota
treatment sulforaphane synergy epigenetic natural compound xenohormesis anticancer miR-663 tyrosine kinase inhibitors acetylation epidemiology double-blinded inflammation bladder cancer polypharmacology animal model synbiotics resveratrol royal jelly 5-aza-2'-deoxycytine saponins phenolics cardiovascular disease antioxidant colorectal cancer trypsin inhibitors seeds green tea Gac randomized clinical trial melanoma adverse events extraction microbiome Momordica cochinchinensis freeze dried extract renal cell carcinoma methylation cancer probiotics |
| ISBN | 3-03921-366-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367758003321 |
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Barrajon Enrique
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments
| Non-small Cell Lung Cancer: Current Therapies and New Targeted Treatments |
| Autore | Uchino Junji |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
non-small cell lung cancer
previously treated patients phase I/II trial chemotherapy docetaxel S-1 immunotherapy rechallenge retrospective analysis pulmonary pleomorphic carcinoma prognostic factor glucose transporter 1 lung cancer multiple cancers metastasis sequencing mutation genomic diagnosis FDG-PET immune checkpoint inhibitor PD-1 prognosis RAD51B methylation PD-L1 expression predictive biomarker PD-1 blockade interstitial lung disease pulmonary fibrosis radiology and other imaging non-small-cell lung cancer epidermal growth factor receptor tyrosine kinase inhibitors TP53 mutations responsiveness targeted therapy network meta-analysis stage IIIA-N2 surgery immune checkpoint inhibitors biomarker nonsmall cell lung cancer HIP1R PD-L1 RUNX1 methylation survival EGFR-TKI T790M osimertinib immune-related adverse events endocrine disorders tumor-bearing patients PD-1 inhibitors PD-L1 inhibitors meta-analysis nivolumab Expanded Access Program real-world data daily practice prognostic factors NSCLC KRAS DNA polymerase beta platinum-based first-line adjuvant chemotherapy β-catenin lung neoplasms nucleotide-diphosphate kinase recurrence unresectable salvage surgery oligometastasis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Non-small Cell Lung Cancer |
| Record Nr. | UNINA-9910557489703321 |
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Uchino Junji
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Paediatric Formulation: Design and Development
| Paediatric Formulation: Design and Development |
| Autore | Denora Nunzio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (205 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
dasatinib
Duchenne muscular dystrophy cyclodextrin inclusion complex phase solubility studies paediatric age liquid formulation tumorspheres retinoblastoma topotecan penetration confocal microscopy poorly water soluble drug solubility enhancement grinding spray congealing neglected tropical diseases polymorph Norvir® ritonavir poorly soluble compound pediatric palatability assessment bioavailability flavor profile Interleukin-1 anakinra canakinumab innovative biotechnologies autoinflammatory disease Kawasaki disease systemic juvenile idiopathic arthritis personalized medicine child pediatrics neonates formulation product development formulation development oral parenteral topical inhaled intra nasal biopharmaceutics administration excipient NICU device medication error dosage form modified release drug delivery paediatric formulation development paediatric dosage forms chronic myeloid leukemia tyrosine kinase inhibitors pediatric age imatinib nilotinb ponatinib Orodispersible formulation pyrazinamide pediatric drug delivery tuberculosis design of experiments children edible films development design paediatric age-related palatable taste-masking acceptable |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Paediatric Formulation |
| Record Nr. | UNINA-9910557304003321 |
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Denora Nunzio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Developments in Annexin Biology
| Recent Developments in Annexin Biology |
| Autore | Jaiswal Jyoti K |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (266 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
inflammation
nigericin pyroptosis mass spectrometry lipidomics anxA2 Birbeck granules Langerhans cell A2t annexin plasma membrane repair membrane curvature membrane curvature sensing membrane shaping interdisciplinary research cell rupture membrane damage bias analysis G protein-coupled receptor (GPCR) formyl peptide receptor 1 danger-associated molecular pattern (DAMP) pathogen-associated molecular pattern (PAMP) annexin A1 peptide Ac2-26 cholesterol AnxA6 chaperone-mediated autophagy endolysosomes NPC1 Lamp2A annexin A2 microdomain cross-linker quartz crystal microbalance with dissipation monitoring (QCM-D) mucin-1 claudin-1 zona occludens ERK1/2 pathway angiogenesis F-actin polymerization BeWo spheroids Ishikawa cells influenza RNA-sequencing transcriptomics autophagy Annexin-A1 infection adherens junction macroautophagy breast cancer estrogen receptor negative Annexin A2 metastasis annexin-A6 membrane repair human skeletal muscle cap subdomain fluorescence electron microscopy CLEM annexin A6 RasGRF2 EGFR cell growth cell motility acquired resistance tyrosine kinase inhibitors muscle injury plasma membrane vesicle muscular dystrophy annexinA2 egress exocytosis chromaffin cells thrombosis Annexin A1 formyl peptide receptors sickle cell disease sepsis Annexin membrane injury virus lipid cancer |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557351303321 |
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Jaiswal Jyoti K
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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