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Advance in the Treatment of Pediatric Leukemia
| Advance in the Treatment of Pediatric Leukemia |
| Autore | Handgretinger Rupert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (300 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
5-azacitidine
ABCC4 acute lymphoblastic leukemia acute myeloid leukemia acute pancreatitis ADC advances ALL allogeneic stem cell transplantation alternative donors AML antibody antibody-drug conjugate B-ALL BCL11B BCP-ALL bispecific T-cell engager (BiTE) CD19 CFTR childhood acute lymphoblastic leukemia children chronic myeloid leukemia CML conditioning regimen COVID-19 diagnosis DUX4 evolution of CAR T cells Fc-engineering FDA-approved CAR products future directions of CAR T cell therapy genome hematopoietic stem cell transplantation IKZF1 immunizations immunotherapy juvenile myelomonocytic leukemia L-asparaginase leukemia limitations and complications of CAR T cell therapy low-risk ALL lymphoblastic leukemia minimal residual disease myelodysplastic/myeloproliferative disorders n/a NOTCH1 NUTM1 other extramedullary relapse PAX5 pediatric pediatric leukemia Ph-like polymorphism prognosis RAS signaling risk-stratified treatment SNV T-ALL targeted therapy TcR versus CAR TRAIL transcriptome treatment treatment related toxicity tyrosine kinase inhibitor xenograft ZNF384 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576878903321 |
Handgretinger Rupert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Precision Medicine in Solid Tumors
| Precision Medicine in Solid Tumors |
| Autore | Dey Nandini |
| Descrizione fisica | 1 online resource (304 p.) |
| Soggetto topico |
Medicine and Nursing
Oncology |
| Soggetto non controllato |
adjuvant chemotherapy
anaplastic lymphoma receptor tyrosine kinase breast cancer cancer cancer-associated fibroblasts cfDNA chemotherapy circulating free DNA clinical guideline clonality classification comprehensive genomic profiling CTC ctDNA DDR genes Decision tree digital enrichment driver mutation EGFR mutation EGFR-TKI electronic records epidermal growth factor receptor extent of resection gene panel sequencing glioblastoma prognosis HNSCC immune checkpoint inhibitors immunocytochemistry immunotherapy intratumor heterogeneity laboratory-friendly liquid biopsy molecular barcoding molecular genotyping multiple biopsies n/a new drug development next-generation sequencing next-generation sequencing (NGS) NGS non-small cell lung cancer open data osimertinib outcome overall survival parallel double-detection PARP inhibitors PD-L1 pediatric tumors personalized precision oncology precision medicine presumed germline findings random forest regulatory reform resistance screening sequencing smoking solid cancer strategic therapeutic intervention targeted therapy tDNA thymoma TMB TNBC subtypes triple-negative breast cancer (TNBC) tumor evolution tumor mutational burden tumor profiling test tyrosine kinase inhibitor universal health-care system whole-exome sequencing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595078103321 |
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Dey Nandini
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| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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