Advances and Novel Treatment Options in Metastatic Melanoma |
Autore | Facchiano Antonio |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (528 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
melanoma
invasion WNT5A MARCKS phosphorylation MANS peptide nanoparticles cell therapy tumor microenvironment sex/gender sex-hormones immunity microRNAs immunotherapy BRAF-mutant melanoma BRAF inhibitor mechanism of action targeted therapy tumour microenvironment plasmacytoid dendritic cells lactate dehydrogenase TLR interferon CXCL10 TPC2 HIPPO SOCE metastasis essential oils angiogenesis apoptosis uveal melanoma (UM) metastatic uveal melanoma (mUM) prognostication adjuvant therapy metastatic therapy metastatic dormancy liver-directed-therapies targeted-therapy combined therapy protein tyrosine phosphatase PTPs inhibitors melanoma immune infiltrate BRAF inhibitors microenvironment resistance therapy therapeutic resistance exosomes extracellular vesicles diagnosis prognosis ctDNA liquid biopsy prediction patient stratification BRAF arthralgia rheumatoid arthritis carbonic anhydrase hedgehog cyclopamine small molecules acetazolamide motility metalloproteinases FAK cancer mucosal melanoma nivolumab pembrolizumab ipilimumab radiotherapy cholinergic system acetylcholine muscarinic receptors nicotinic receptors melanoma metastasis ShcD adaptor protein amoeboid motility Rac1 DOCK4 melanoma PDX target therapy cancer stem cells slow cycling phenotype drug resistance OXPHOS lipid metabolism cancer associated fibroblast melanomagenesis biomarkers checkpoint inhibitor PD-1 melanoma markers cytokines machine learning Support Vector Machine principal component analysis BCL2L10 STAT3 cytotoxicity survival ABT-737 Bcl-2 family ML258 HuR MITF metastases siRNA |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Advances in epithelial ovarian cancer [[electronic resource] ] : model systems, microenvironmental influences, therapy, and origins / / edited by Viive Maarike Howell, Ben Davidson, Tian-Li Wang and Christina Annunziata |
Autore | Ben Davidson |
Pubbl/distr/stampa | Frontiers Media SA, 2016 |
Descrizione fisica | 1 online resource (176 pages) : illustrations; digital, PDF file(s) |
Disciplina | 616.99465 |
Collana |
Frontiers Research Topics
Frontiers in oncology |
Soggetto topico |
Ovaries - Cancer - Research
Neoplasms Oncology |
Soggetto non controllato |
3D-cell culture
Ovarian cancer stem cells ovarian cancer tumor-associated macrophage BRCA chemoresistance fallopian tube tumour microenvironment mouse models of ovarian cancer patient derived xenografts primary ovarian tumour cells Ascites |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910136793403321 |
Ben Davidson | ||
Frontiers Media SA, 2016 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cancer Nanomedicine |
Autore | Hoskins Clare |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (510 p.) |
Soggetto topico | Technology: general issues |
Soggetto non controllato |
antibody drug conjugate (ADC)
PD-L1 tumor spheroid disruption immune modulation doxorubicin graphene oxide adsorption cathepsin D cathepsin L anti-metastatic enzyme cancer therapy nanoparticles targeted delivery system siRNA osteopontin mammary carcinoma mesenchymal stem cells (MSCs) TAT peptide PLGA paclitaxel nano-engineered MSCs orthotopic lung tumor model intracranial glioma immunotherapy CPMV viral nanoparticles in situ vaccine albumin nanoparticles microbubble ultrasound theranostics hepatocellular carcinoma VX2 tumor intra-arterial chemotherapy lung cancer nanomedicine clinical status cancer therapy breast cancer cell signaling active targeting passive targeting EPR effect oncogenes nanoparticle drug delivery ligand tumor targeting biodistribution Mesoporous silica nanoparticle drug delivery system target treatment lanthanide metal hyaluronic acid hyaluronidase drug combination everolimus dual-targeting magnetic nanoparticles monoclonal antibodies nanostructured lipid carrier platelet membrane biomimicry plasmonic photothermal therapy gold nanorods surgery bleeding dogs cats stimuli-responsive DOX SN38 CSCs single-walled carbon nanotubes chirality separation NASH drug-gene delivery near IR hyperspectral imaging plasmonics copper VEGF glioblastoma differentiated neuroblastoma peptidomimetics real-time quantitative polymerase chain reaction (qPCR) actin combinatorial therapy anticancer and antibacterial activity temoporfin drug-in-cyclodextrin-in-liposome hybrid nanoparticles multicellular tumor spheroids cyclodextrins photodynamic therapy article yet reasonably common within the subject discipline antitumor strategy biomimetic core–shell nanoparticles NK cell-derived exosomes folate receptor albumin nanoparticle microfluidic cabazitaxel polydopamine nanoparticles size cytotoxicity iron affinity FA-DABA-SMA self-assembly oncogenic proteins intracellular disruption folic receptor alpha pancreatic cancer parvifloron D albumin erlotinib photodynamic therapy lipid nanoparticles tumor vectorization verteporfin ovarian carcinomatosis spheroids integrin RGD peptide cancer diagnosis radiotherapy hyperthermia therapy biomimetic nanocarrier membrane-wrapped cancer targeted delivery photothermal therapy imaging cancer nanomedicine tumor microenvironment nano–bio interactions clinical translation magnetic nanowires magnetic hyperthermia magnetic actuation magnetic drug targeting titanate nanotubes gold nanoparticles vectorization colloidal stability docetaxel prostate cancer mangiferin anti-topoisomerase activity extracellular vesicles exosomes chemico-physical functionalization loading translational medicine nanotechnology: bioengineering anacardic acid mitoxantrone targeted drug delivery liposomes melanoma apoptosis ascorbic acid angiogenesis epithelial-to-mesenchymal transition hypoxia immunosuppression metabolism nanotherapeutics tumour microenvironment DNA origami liposome remote loading acute toxicity organoids magnetic silica-coated iron oxide nanochains photothermal treatment hyperthermia collagen cellular microenvironment lymphadenectomy magnetometer sentinel lymph node dissection SPION superparamagnetic iron oxide nanoparticles Vδ2 T cells zoledronic acid polymeric nanoconstruct anti-tumor immunity colorectal carcinoma β-cyclodextrin nanosponges BALB-neuT mice brain tumours glioma blood brain barrier polymeric nanoparticles PEGylation dioleoylphosphatidylethanolamine poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer folate oxidation-sensitive release cellular interaction in vitro anti-cancer activity triple negative breast cancer organotin mesoporous silica nanoparticles MDA-MB-231 theranostic nanomaterials nanobiotechnology molecular imaging nanosystems nanomicelles ovarian cancer tumour targeting chemotherapeutics riboflavin vitamin B2 nanomedicines secondary structure mixed micelle pH responsive targeted therapy anti-cancer shear stress flow in vitro therapeutics diagnostics Immunotherapy |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557114703321 |
Hoskins Clare | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications |
Autore | Ishii Kenichiro |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (184 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
androgen receptor
docetaxel cabazitaxel castration-resistant prostate cancer chemotherapy P-glycoprotein EPI-002 splice variant prostate-specific antigen androgen deprivation therapy time to PSA nadir fibroblasts prostate cancer androgen sensitivity pirfenidone TGFβ1 G1 cell cycle arrest fibroblast growth factor fibroblast growth factor receptor obesity inflammation immune cells cytokine high-fat diet KIFC1 docetaxel resistance apoptosis CW069 Caveolin-1 TP53-regulated inhibitor of apoptosis 1 tumour stroma tumour microenvironment fibroblast CAF resistance radiotherapy CCL2 CCL22 CCL5 migration LSD1 epigenetics autophagy abiraterone enzalutamide testosterone castration resistant prostate cancer animal model diet fat in vitro in vivo mouse AKR1C3 hormone-naïve prostate cancer immunohistochemistry tissue microarray androgen receptor dependency fibroblast-dependent androgen receptor activation |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557116703321 |
Ishii Kenichiro | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Novel Biomarkers of Gastrointestinal Cancer |
Autore | Shimura Takaya |
Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
Descrizione fisica | 1 electronic resource (248 p.) |
Soggetto topico |
Medicine
Oncology |
Soggetto non controllato |
colorectal cancer
advanced adenoma screening stool mRNA cancer screening cirrhosis AFP machine learning MALDI-TOF proteomics CXCR4 prognosis overall survival rectal cancer neoadjuvant chemoradiation mouse model biomarkers urokinase plasminogen activator (uPA) urokinase plasminogen activator receptor (uPAR) plasminogen activator inhibitor type 1 (PAI-1) circulating tumour cell (CTC) gastric cancer oesophageal cancer serine proteases tumour microenvironment serpins biomarker chemoresistance liquid biopsy microRNA long non-coding RNA colorectal neoplasms cancer screening tests early detection of cancer precision medicine unfolded protein hepatocellular cancer GSVA unfolded protein score epigenetic regulation genes somatic mutations molecular genetic markers extracellular vesicles microbiome 16S rRNA amplicon metagenomics liver fibrosis hepatocellular carcinoma recurrence SHG/TPEF microscopy artificial intelligence advanced gastric cancer targeted therapy urinary miRNA miR-129-1-3p miR-566 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910595076103321 |
Shimura Takaya | ||
Basel, : MDPI Books, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Radiation Response Biomarkers for Individualised Cancer Treatments |
Autore | Badie Christophe |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (231 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
carbon-ion radiotherapy
head-and-neck tumors squamous cell carcinoma radiosensitivity relative biological effectiveness lung cancer radiotherapy radiotherapy monitoring radiation-induced lung injury RILI pneumonitis radiation-induced lung fibrosis RILF circulating biomarkers microRNA micronuclei uterine cervical cancer cGAS STING abscopal effect immunotherapy PBMCS micronucleus assay biological dosimetry human blood genotoxicity tests ionizing radiation biomarkers dicentric assay gamma H2AX foci assay health surveillance analyses clonogenic assays methods plating cancer radiation head and neck cancer exosomes serum metabolomics GC/MS biodosimetry chromosome aberrations normal tissue toxicity predictive tests normal tissue biomarker protein immune infiltrate stroma tumour microenvironment proteomics telomeres chromosomal instability inversions prostate cancer IMRT machine learning individual radiosensitivity late effects personalized medicine liquid biopsy circulating tumour cells extracellular vesicles microRNAs immune system inflammation |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557345403321 |
Badie Christophe | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy |
Autore | Madureira Patrícia Alexandra Saraiva |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (307 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
hypoxia
macrophages colon cancer tumor microenvironment immune cell infiltration prognosis feline mammary carcinoma PD-1 PD-L1 CTLA-4 TNF-α biomarkers immunotherapy cancer histone modification inhibitor KDM5B molecular docking repurposing cancer acidity hyperosmolarity cross-presentation tumour microenvironment syngeneic model prostate cancer radiotherapy preclinical modelling myeloid-derived suppressor cells biomarker stroma cancer-associated fibroblast (CAF) extracellular matrix (ECM) cytokine/chemokine growth factors pro- and anti-tumor immune cells immunomodulatory roles radiotherapy dose fractionation radioresistance radiosensitivity breast cancer S100A10 (p11) tumor growth tumor progression metastasis carcinoma mammary gland triple negative pre-metastatic niche pro-inflammatory cytokines clinical trials evolutionary therapy darwinian evolution cancer cells subpopulations diclofenac koningic acid spheroid 3D co-culture microenvironment resistance myeloid cells cancer development molecular subtypes of pancreatic cancer chemotherapy response pancreatic stellate cells regulatory T cells tumor-associated macrophages myeloid derived suppressor cells glioblastoma (GB) Hypoxia Inducible Factor (HIF) glioma stem cells (GSC) oxidative stress reactive oxygen species plasmin plasminogen S100A10 uPA uPAR PAI-1 PAI-2 cancer stem cells cancer recurrence therapeutic resistance signaling pathways targeted therapy head and neck cancer lung cancer bladder cancer |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557354203321 |
Madureira Patrícia Alexandra Saraiva | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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