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Animal Modeling in Cancer
| Animal Modeling in Cancer |
| Autore | Korinek Vladimir |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (273 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
animal model
animal models antitumor immunity brain and nervous system cancers CALR cancer carcinoma Cdx chemical carcinogens colorectal cancer consensus molecular subtypes devitalization Drosophila drug screen epigenetics ETO-1 FLT3 ITD gene editing gene inactivation genetics hematologic malignancies IDH1/2 intestine iPSCs isoflavones JAK2 mammary tumor prevention melanoma MeLiM metaplasia mice microbiota mouse model mouse models MPL MPN (myeloproliferative neoplasms) mutation neural stem cells neurogenic niches non-mouse models NPM-1 oncogenes pre-clinical cancer model progression radiotherapy rats rodent models signaling cascades solid tumors soy sparing of neurogenic regions spontaneous regression stem cells swine thrombosis transgenic mice tumor suppressors tumorigenesis ubiquitin-proteasome system xenotransplantation zebrafish Zebrafish |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557344403321 |
Korinek Vladimir
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Drugs / Niamh M. O'Boyle, Mary J. Meegan
| Anticancer Drugs / Niamh M. O'Boyle, Mary J. Meegan |
| Autore | O'Boyle Niamh M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (214 p.) |
| Soggetto topico | Chemistry |
| Soggetto non controllato |
graphene oxide
indole androgens cyclooxygenase-2 cyclooxygenase-1 heteropolysaccharide drug conjugation drug delivery ellipticine chemical linker oesophageal cancer antiproliferative activity topoisomerase II ?-lactam DSD antibody topoisomerase inhibitors magnetic targeting cisplatin resistance steroidogenesis [18F]FDG PET/CT heterocyclic chemistry dehydroepiandrosterone antimitotic 3-vinylazetidin-2-ones glioblastoma and cancer therapy intestinal mucositis Combretastatin A-4 metabolism anti-cancer drugs maghemite COX-1 inhibitor anticancer CYP17A1 conjugate and hybrid drugs inflammation snticancer drugs P450c17 tumorigenesis cisplatin biomarker profiling cancer drug design tubulin cytochrome P450 5-fluorouracil prostate cancer abiraterone NCI screen radiation cancer immunotherapy microtubule targeted drugs cancer treatment resistance |
| ISBN |
9783039215874
3039215876 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367753903321 |
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O'Boyle Niamh M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Inhibitors
| Anticancer Inhibitors |
| Autore | Fantacuzzi Marialuigia |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (216 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
breast cancer
tamoxifen LY294002 synergism apoptosis cell cycle tea (Camellia sinensis) flowers BTFS A2780/CP70 ovarian cancer cells S phase cell cycle arrest nicotinamide phosphoribosyltransferase NAD+ biosynthesis inhibitor azacyclohexane anticancer drug drug design enthalpy effect NSCLC Cathepsin K cell proliferation cell migration cell invasion mTOR isatin-hydrazones cytotoxicity CDK2 inhibitor ATP competitive inhibitor ADME analysis receptor tyrosine kinases protein-protein interactions protein engineering directed evolution angiogenesis binding affinity agonistic activity saponins phytochemicals tea (Camellia sinensis) flower ovarian cancer autophagy ZMYND8 tumorigenesis epigenetic regulation pro-oncogenic effects tumor suppression tacrine-coumarin derivatives DNA topoisomerases I, II lung carcinoma cells A549 chemotherapy prodrug drug targeting overexpressed enzymes ADC ADEPT GDEPT LEAPT PROTAC cyclin-dependent kinase cancer resistance small molecule inhibitors PROTACs statins pancreatic cancer DNA microarray pitavastatin cerivastatin simvastatin fluvastatin atorvastatin pravastatin HMG-CoA reductase inhibitors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069203321 |
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Fantacuzzi Marialuigia
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Apoptotic Cell Clearance in Health and Disease
| Apoptotic Cell Clearance in Health and Disease |
| Autore | Amiram Ariel |
| Pubbl/distr/stampa | Frontiers Media SA, 2018 |
| Descrizione fisica | 1 online resource (294 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Apoptosis
development Efferocytosis Homeostasis immune-regulation neurodegeneration Phagocytes receptor-ligand interactions tumorigenesis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346757403321 |
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Amiram Ariel
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| Frontiers Media SA, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomarkers for Diagnosis, Complications and Therapy Effects in Civilization Diseases Management
| Biomarkers for Diagnosis, Complications and Therapy Effects in Civilization Diseases Management |
| Autore | Komosinska-Vassev Katarzyna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (208 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
adipokines
adiponectin antiplatelet therapy bone turnover markers breast cancer cardiovascular disease case control study CCL11 CCL24 CCL26 CCR3 CRC Crohn's disease Crohn's disease (CD) CTX-I dendritic cells diabetes extracellular matrix extracellular matrix components FSHR hedgehog-interacting protein hyaluronan hyaluronan (HA) impaired fasting glucose impaired glucose tolerance inflammatory bowel disease inflammatory bowel diseases (IBD) innate lymphoid cells interleukin 21 interleukin 22 Let-7e lymphocytes macrophages microRNA miR-125a-3p miR-126 miR-223 mortality newly diagnosed diabetes NGS variants normal glucose tolerance NTX-I obesity ovarian cancer overweight personalized drug therapy personalized medicine pharmacogenomics PICP PINP platelet reactivity proteins RANKL/OPG rheumatoid arthritis rheumatology soluble part of syndecan-1 (sCD138) sulfated glycosaminoglycans (sGAG) TNF-α inhibitors tumor microenvironment tumorigenesis ulcerative colitis ulcerative colitis (UC) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566458203321 |
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Komosinska-Vassev Katarzyna
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diagnostic, Prognostic and Predictive Biological Markers in Bladder Cancer - Illumination of a Vision 2.0
| Diagnostic, Prognostic and Predictive Biological Markers in Bladder Cancer - Illumination of a Vision 2.0 |
| Autore | Ecke Thorsten |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (240 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
adjuvant chemotherapy
androgen receptor BCG therapy biomarker biomarkers BIRC5 bladder bladder cancer bladder cancer detection cadmium exposure cancer chemotherapy combination therapy DNA methylation drug resistance ECRG4 ERBB2 F-actin FGFR3 grade heparan sulfate proteoglycans (HSPGs) heparanase histone demethylase immunotherapy invasion ITIH5 JAK inhibitor JAK-STAT pathway KDM7A KRT20 macrophage metabolomics Metallothionein MIBC miRNA MS muscle-invasive bladder cancer n/a NMR non muscle invasive bladder cancer non-invasive detection oncolytic adenovirus p53 personalized medicine prediction predictive biomarker prognosis proliferation PTEN quantitative PCR RT-qPCR somatic mutations STAT3/5 inhibitor survival survivin syndecan-1 TAGLN TC-E 5002 telomerase TERT promoter mutations TERT promoter region tumor marker tumor markers tumorigenesis urinary biomarkers urothelial cancer urothelial carcinoma urothelium virotherapy voided urine cytology XVir-N-31 zinc transporter |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557142003321 |
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Ecke Thorsten
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Disease and the Hippo Pathway: Cellular and Molecular Mechanisms
| Disease and the Hippo Pathway: Cellular and Molecular Mechanisms |
| Autore | Hansen Carsten Gram |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (226 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
adaptive immunity
angiogenesis anti-cancer therapy autoimmunity cancer cancer immunity castration resistance chromatin ECM EMT epigenetic feedback loops fibroblasts fibrosis G protein-coupled receptor GPCR Hippo hippo pathway Hippo pathway Hippo signalling innate immunity LATS LATS (large tumor suppressor kinase) LATS1/2 Lats2 Mps one binder MST MST (mammalian STE20-like protein kinase) MST1/2 myofibroblast n/a NDR peripheral nerve sheath tumor phosphorylation prostate cancer protein kinase protein-protein interactions schwannoma signal cross-talk signal transduction skin cancer skin development stem cell stem cells STK38 STRIPAK structure biology Taz TAZ TAZ (transcriptional co-activator with PDZ-binding motif) TEAD transcription tumorigenesis vascular mimicry wound healing Yap YAP YAP (yes-associated protein) YAP/TAZ zebrafish |
| ISBN | 3-03921-777-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Disease and the Hippo Pathway |
| Record Nr. | UNINA-9910367742003321 |
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Hansen Carsten Gram
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Head and Neck Critical Illness : Basic and Clinical Research Implications
| Head and Neck Critical Illness : Basic and Clinical Research Implications |
| Autore | Tomita Hiroyuki |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (258 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
11q13
4-IPP abscess aldehyde dehydrogenase 1 (ALDH1) allocentric annexin A10 annexin A9 antibiotic therapy ANUBL1 apparent diffusion coefficient autoimmune encephalitis autophagy bacterial meningitis BDNF biomarker Brain-Derived Neurotrophic Factor canaloplasty cellulitis cervical concurrent chemoradiotherapy corticosteroid-induced glaucoma CT deep neck infection diabetes mellitus differential diagnosis differentiation grade diffuse large B-cell lymphoma diffusion-weighted MRI doxorubicin gene amplification genetic polymorphism head and neck head and neck cancer head and neck squamous cell carcinoma head and neck squamous cell carcinoma (HNSCC) hippocampus HNSCC HPV human cancer human papillomavirus immunohistochemistry infectious encephalitis influx malignant tumor MAP1LC3B metabolism MIF MRI myeloid-derived suppressor cells (MDSC) navigation neck mass neuropsychiatric presentation of encephalitis neutrophil-to-lymphocyte ratio (NLR) neutrophil/lymphocyte ratio NGS non-perforating surgical procedures Nox4 nucleotide excision repair oral cancer oral squamous cell carcinoma oral tongue cancer paraneoplastic encephalitis Post-Traumatic Stress Disorder priming procalcitonin prodigiosin prognosis PSTD radiotherapy reduction therapy Schlemm's canal sinonasal tract spatial processing SQSTM1 squamous cell carcinoma subsites surgery survival trauma trauma processing tumorigenesis viral meningitis ZFAND4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Head and Neck Critical Illness |
| Record Nr. | UNINA-9910557535203321 |
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Tomita Hiroyuki
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Physiological and Pathological Role of ROS: Benefits and Limitations of Antioxidant Treatment
| Physiological and Pathological Role of ROS: Benefits and Limitations of Antioxidant Treatment |
| Autore | Di Meo Sergio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (236 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
AMPK pathway
antioxidant supplementation AP-1 apoptosis artemisinin atherosclerosis c-FLIP cancer cancer therapy cardiomyocytes cardiotoxicity cardiovascular disease cavefish cell viability chromophobe RCC clear cell RCC CORM-2 CTCL D-box DNA damage endoplasmic reticulum stress endothelial dysfunction evolution exercise glutathione (GSH) metabolism H2O2 hippocampal neurons HO-1 insulin resistance light mitochondria mitochondrial membrane potential n/a NADPH oxidase neurodegenerative disorders Nrf2 oxidative stress papillary RCC peroxiredoxins PGC-1 protein aggregation proteinopathy reactive oxygen species reactive oxygen species (ROS) redox redox signaling Renal cell carcinoma (RCC) ROS ROS scavengers sarcopenia SH-SY5Y cells Spalax sphingomyelin synthase 2 trimethylamine N-oxide tumorigenesis UCPs XIAP β-catenin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Physiological and Pathological Role of ROS |
| Record Nr. | UNINA-9910557430503321 |
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Di Meo Sergio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting STAT3 and STAT5 in Cancer
| Targeting STAT3 and STAT5 in Cancer |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (578 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
ADAM17
adoptive T cell therapy AKT androgens apoptosis autoimmune disease autosomal-dominant hyper IgE syndrome Bone Marrow Failure Syndromes breast cancer cancer cancer models cancer progression cancer-stem cell CD38 CD4+ T cells CD8+ T cells cell cycle cell hierarchy chaperones chemotherapy resistance cirrhosis colon cancer companion animals comparative oncology cytokine cytokine receptor signaling dynamic programming endoplasmic reticulum (ER) stress epidermal growth factor receptor (EGF-R) ERK1/2 escape mechanisms gain-of-function mutation glioblastoma glioma growth hormone insensitivity syndrome heat shock proteins hedging hematopoietic cancers hepatitis C virus (HCV) hepatocellular carcinoma (HCC) hepatocyte nuclear factor 4 alpha (HNF4A) immune check point immune suppression immunosuppression immunotherapy inflammation inflammation associated cancer inflammatory hepatocellular adenomas interleukin-6 JAK JAK family of protein tyrosine kinases JAK2 V617F knockout lipopolyplex lung cancer lymphocytes lymphoma M2 macrophages melanoma meta-analysis metalloprotease metastasis microRNA-122 (miR-122) mitochondria MPN mTOR multiple myeloma mutations myeloid cells myeloid leukemia n/a nanoparticle neoplastic stem cells NGS NK cells nuclear factor erythroid 2-related factor 2 (NRF2) nuclear pore complex nuclear transport receptors nucleocytoplasmic shuttling ovarian cancer oxidative stress (OS) PD-L1 PEI pharmacological inhibitor pharmacological inhibitors polyethylenimine post-decision state variable prolactin proliferation prostate cancer RHOA risk management S3I-1757 SH2 domain shedding signal transducer and activator of transcription signal transducer and activator of transcription 3 (STAT3) siRNA delivery siRNA/RNAi small-molecule inhibitors solid cancers stabilization STAT STAT transcription factors STAT3 STAT3 inhibitor XIII STAT5 STAT5 signaling STAT5B signaling stem/progenitor cells stemness T-cell large granular lymphocytic leukemia T-cell leukemia T-cell prolymphocytic leukemia T-cells T-PLL targeted therapy targeting therapeutic targeting therapy resistance trans-signaling transaction costs tumor microenvironment tumor necrosis factor alpha (TNFα) tumor suppression tumor-associated macrophages tumor-immune cell interactions tumorigenesis tyrosine kinase 2 unfolded protein response (UPR) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557623503321 |
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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