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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (606 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
benzofurans
chemical synthesis cytotoxic properties HeLa MOLT-4 K562 anticancer anti-neuroinflammation coumarin dihydroartemisinin flavonoids allene E-stereoselective regioselective anti-cancer activity cyanopyridone substituted pyridine pyridotriazine pyrazolopyridine thioxotriazopyridine anticancer activity HepG2 antitumor activity computational docking MDM2-p53 interaction xanthones yeast-based assays estrone derivatives hydrazine N-substituted pyrazoline anti-ovarian cancer topoisomerase II inhibitor kinase inhibitor antiproliferative agent urea synthesis antiproliferative activity apoptosis indoleamine 2,3-dioxygenase inhibitor anti-tumor immune modulation tryptophan metabolism taxoids βIII-tubulin P-glycoprotein drug resistance thiopene thienopyrimidinone thiazolidinone breast cancer benzofuran–pyrazole nanoparticles cytotoxic activity PARP-1 inhibition 3,6-dibromocarbazole 5-bromoindole carbazole actin migration Thienopyrimidine Pyrazole PI3Kα inhibitor quinazolin-4(3H)-one quinazolin-4(3H)-thione Schiff base antioxidant activity DFT study ortho-quinones beta-lapachone tanshione IIA PI3Ks PI3Kδ inhibitors 2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide anticancer agents protein–protein interactions virtual screening mimetics drug discovery bivalency polyvalency antitumor cell cycle ovarian cancer P-MAPA IL-12 TLR signaling inflammation chemoresistance 4-(pyridin-4-yloxy)benzamide 1,2,3-triazole c-Met natural product anticancer agent zampanolide Talazoparib PARP inhibitor prodrug o-nitro-benzyl photoactivatable protecting groups salinomycin overcoming drug resistance tumor specificity synergy 5-fluorouracil gemcitabine amides/esters colchicine analogs thiocolchicine colchiceine antimitotic agents hydrates dihydropyranoindole HDAC inhibitors neuroblastoma aromatase MCF-7 NIH3T3 benzimidazole triazolothiadiazine docking ADME organosilicon compounds SILA-409 (Alis-409) SILA-421 (Alis-421) multidrug resistance (MDR) reversal ABCB1 (P-glycoprotein) colon cancer colchicine amide colchicine sulfonamide tubulin inhibitors docking studies crystal structure PROTACs protein degradation IGF-1R Src protein kinase phenylpyrazolopyrimidine enzyme inhibition molecular simulation androgen receptor prostate cancer enzalutamide apalutamide darolutamide triple-negative breast cancer cytotoxicity chrysin analogues flavonoid anticancer compounds |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Research Topics in Medicines and How Our Board Members Are Engaged in Them
| Research Topics in Medicines and How Our Board Members Are Engaged in Them |
| Autore | Sakagami Hiroshi |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Hedychium
traditional medicine coronarin D villosin anti-acetylcholinesterase antidiabetic anti-inflammatory antimicrobial antioxidant antitumor Genista tridentata Pterospartum tridentatum isoflavones flavonols genistein biochanin A rutin daidzein inflammatory bowel disease Crohn’s disease ulcerative colitis extra-intestinal manifestations orofacial granulomatosis tag-like lesions cobblestoning mucogingivitis lip swelling aphthous stomatitis Angelicae Sinensis Radix Danggui granules herb multivariate analysis ultra-performance liquid chromatography Tai Chi qigong immune system immunity inflammation telemedicine remote monitoring GER-e-TEC elderly patient artificial intelligence geriatric syndromes detection of the precursory signs of decompensation of geriatric syndromes renal cell cancer genomic landscape targeted therapy tumor evolution tumor heterogeneity allergic rhinitis quercetin human CD4+ T cells Th1/Th2 cytokine balance modulation in vitro intravascular catheter CRBSI biofilm CVC antifouling chromone tumor specificity QSAR analysis apoptosis cell cycle analysis contrast-enhanced ultrasound hepatocellular carcinoma LI-RADS chronic liver disease granuloma annulare granulomatous disorders of the skin inflammatory skin conditions medical dermatology biliary tract cancer cholangiocarcinoma PARP BRCA olaparib rucaparib liver cancer pancreatic adenocarcinoma pancreatic cancer sarcoidosis superior vena cava syndrome venous thrombosis RUCAM Roussel Uclaf Causality Assessment Method diagnostic algorithm iDILI iDrug induced liver injury DILI HILI herb induced liver injury Stachys L. traditional uses pharmacological activities phytochemicals bioactive compounds Kampo formulae alkaline extract of Sasa sp pine cone extract povidone-iodine HSV HIV loss of infectivity solubilization method diaphragmatic breathing abdominal breathing breathing exercise systematic review randomized controlled trial respiratory function auricular acupuncture preoperative anxiety protocol randomized controlled trials meta-analysis boiogito knee osteoarthritis rat Yokukansan fentanyl transient receptor potential ankyrin 1 (TRPA1) channel phosphorylated extracellular signal-regulated kinase (pERK) whole-cell patch-clamp recording herbal medicine calcium metabolism bone metabolism protease osteoclast macrophage RANKL LPS TLR4 TREM2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874503321 |
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Sakagami Hiroshi
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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