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In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application
| In Vitro and In Vivo Models of Colorectal Cancer for Clinical Application |
| Autore | Baiocchi Marta |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (222 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Microbiology (non-medical) |
| Soggetto non controllato |
colorectal cancer
organoids 3D bioprinting patient-derived xenograft cancer-on-chip drug combination cancer stem cells drug resistance clinical trials tumor-initiating cells tumor heterogeneity patient-derived cancer models single-cell RNA-sequencing tumor metabolism transcriptional programs tumor cell differentiation immunotherapy methods chromosomal instability DNA damage targeted therapy decitabine colon cancer DNA methylation clinical translation study machine learning patient-derived tumor organoid precision medicine radiation response rectal cancer PDX model CRC mutation analysis histological examination animal models in vitro culture cancer stem cell methods SATB2 colorectal carcinoma prognosis CDX2 circulating tumor cells CTC cluster size-based method ScreenCell® epithelial mesenchymal transition hypoxia HIF-1α immunofluorescence analysis sequential filtration |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585944103321 |
Baiocchi Marta
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles
| Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles |
| Autore | Kahn Michael |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (298 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
Wnt signaling
synovial sarcoma TNIK NCB-0846 MYC hepatitis B virus HBV cancer liver cancer β-catenin TCF/LEF pancreatic cancer pancreatic stellate cells CBP p300 pancreatitis fibrosis just-right signaling APC colorectal cancer RNA-binding proteins Musashi drug discovery Notch signaling cancer therapy fungi secondary metabolite derivative microenvironment Wnt AML drug target signaling colorectal porcupine R-spondin serrated immunotherapy wnt vitamin D colon cancer L1 Wnt target genes cell adhesion NF-κB invasion and metastasis cancer stem cells EMT Lgr5 Wnt/beta-catenin signaling angiogenesis anti-angiogenic therapy gastrointestinal cancers therapeutic targeting of Wnt signaling β-catenin paradox molecular targeting urothelial cancer immune checkpoint inhibitor immunotherapy resistance IBD colitis β-catenin mutations tumor metabolism tumor immunology molecular therapeutics precision medicine astrocytic brain tumors DKKs GSK3β |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Targeting Wnt Signaling in Cancer |
| Record Nr. | UNINA-9910566469503321 |
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Kahn Michael
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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