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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (418 p.) |
| Soggetto non controllato |
cancer treatment
extreme learning independent prognostic power AID/APOBEC HP gene inactivation biomarkers biomarker discovery chemotherapy artificial intelligence epigenetics comorbidity score denoising autoencoders protein single-biomarkers gene signature extraction high-throughput analysis concatenated deep feature feature selection differential gene expression analysis colorectal cancer ovarian cancer multiple-biomarkers gefitinib cancer biomarkers classification cancer biomarker mutation hierarchical clustering analysis HNSCC cell-free DNA network analysis drug resistance hTERT variable selection KRAS mutation single-cell sequencing network target skin cutaneous melanoma telomeres Neoantigen Prediction datasets clinical/environmental factors StAR PD-L1 miRNA circulating tumor DNA (ctDNA) false discovery rate predictive model Computational Immunology brain metastases observed survival interval next generation sequencing brain machine learning cancer prognosis copy number aberration mutable motif steroidogenic enzymes tumor mortality tumor microenvironment somatic mutation transcriptional signatures omics profiles mitochondrial metabolism Bufadienolide-like chemicals cancer-related pathways intratumor heterogeneity estrogen locoregionally advanced RNA feature extraction and interpretation treatment de-escalation activation induced deaminase knockoffs R package copy number variation gene loss biomarkers cancer CRISPR overall survival histopathological imaging self-organizing map Network Analysis oral cancer biostatistics firehose Bioinformatics tool alternative splicing biomarkers diseases genes histopathological imaging features imaging TCGA decision support systems The Cancer Genome Atlas molecular subtypes molecular mechanism omics curative surgery network pharmacology methylation bioinformatics neurological disorders precision medicine cancer modeling miRNAs breast cancer detection functional analysis biomarker signature anti-cancer hormone sensitive cancers deep learning DNA sequence profile pancreatic cancer telomerase Monte Carlo mixture of normal distributions survival analysis tumor infiltrating lymphocytes curation pathophysiology GEO DataSets head and neck cancer gene expression analysis erlotinib meta-analysis traditional Chinese medicine breast cancer TCGA mining breast cancer prognosis microarray DNA interaction health strengthening herb cancer genomic instability |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomaterials for Brain Therapy and Repair
| Biomaterials for Brain Therapy and Repair |
| Autore | Pedron Sara |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (193 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico |
Civil engineering, surveying & building
Mechanical engineering & materials |
| Soggetto non controllato |
3D cell culture
biomaterial disease models Neuron neurodegeneration tumor Blood Brain Barrier (BBB) Brain Disorders Hydrogels iPSC = induced pluripotent stem cell Bioprinting |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557510803321 |
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Pedron Sara
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Current Insights on Lipid-Based Nanosystems
| Current Insights on Lipid-Based Nanosystems |
| Autore | Silva Ana Catarina |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
Echinococcus granulosus
scolicidal nanoliposome juglone apoptotic activity hydrogel SLNs nose-to-brain delivery mucoadhesion quality by design antioxidant activity nasal administration nanostructured lipid carriers solid lipid nanoparticles in vitro cell cultures 3D nasal casts lung cancer targeted drug delivery lipid-based nanocarriers pulmonary delivery dry powder inhalers aerosols liposomes nanoemulsions nanotechnology biologically active compounds dermal drug delivery polyphenols phytophenols skin permeation chemotherapy radiotherapy active targeting passive targeting tumor immunoconjugate traditional liposome stealth liposome triggered release limitations of liposomes drug transfer in vitro release colloidal drug carriers lipid nanoparticles hydrogel beads cholesteryl nonanoate bovine serum albumin skin diseases lipid-based nanosystems cream ointment gel pH-sensitive liposome imidazole anticancer drug delivery multicellular spheroids dapagliflozin Box-Behnken design FTIR DSC XRD SEM AFM in vitro Franz diffusion cells lipid-based nanoparticles nanocarrier surface charge delivery systems chronic treatment mice anti-oxidant activity hepatoprotective effect phospholipid phytosomes Silymarin Colorectal Cancer Niosomes Oxaliplatin Paclitaxel d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) therapeutic nucleic acids schizophrenia quetiapine fumarate glycerosomes central composite rotatable design bioavailability pharmacokinetic |
| ISBN | 3-0365-6165-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639995103321 |
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Silva Ana Catarina
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Essential Facts in Cardiovascular Medicine : Board Review and Clinical Pearls / / Yerem Yeghiazarians
| Essential Facts in Cardiovascular Medicine : Board Review and Clinical Pearls / / Yerem Yeghiazarians |
| Autore | Yeghiazarians Yerem |
| Pubbl/distr/stampa | New Brunswick, NJ : , : Rutgers University Press, , [2017] |
| Descrizione fisica | 1 online resource (164 pages) : illustrations, tables |
| Disciplina | 616.1 |
| Soggetto topico | Cardiovascular system - Diseases |
| Soggetto non controllato |
EKG
cardiac tumor cardio cardiology cardiovascular medicine cardiovascular coronary disease heart disease heart failure heart health heart transplant heart hypertension medical medicine pericardial pharmacology pulmonary treatment tumor vascular |
| ISBN |
0-8135-7969-4
1-78684-765-5 0-8135-7970-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Front matter -- Contents -- Abbreviations -- Preface -- Acknowledgments -- 1. Statistics -- 2. General Cardiology -- 3. Physical Exam -- 4. EKG -- 5. Congenital Heart Disease -- 6. Valvular Heart Disease -- 7. Heart Failure/ Transplant -- 8. Acute Coronary Syndromes -- 9. Pericardial Disease -- 10. Electrophysiology -- 11. Pharmacology -- 12. Pregnancy -- 13. Pulmonary Hypertension -- 14. Peripheral Vascular Disease -- 15. Echocardiography -- 16. Interventional Cardiology -- 17. Cardiac Tumors -- 18. Formulas -- References -- Works Cited -- Index -- About The Author |
| Record Nr. | UNINA-9910795560403321 |
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Yeghiazarians Yerem
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| New Brunswick, NJ : , : Rutgers University Press, , [2017] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Essential Facts in Cardiovascular Medicine : Board Review and Clinical Pearls / / Yerem Yeghiazarians
| Essential Facts in Cardiovascular Medicine : Board Review and Clinical Pearls / / Yerem Yeghiazarians |
| Autore | Yeghiazarians Yerem |
| Pubbl/distr/stampa | New Brunswick, NJ : , : Rutgers University Press, , [2017] |
| Descrizione fisica | 1 online resource (164 pages) : illustrations, tables |
| Disciplina | 616.1 |
| Soggetto topico | Cardiovascular system - Diseases |
| Soggetto non controllato |
EKG
cardiac tumor cardio cardiology cardiovascular medicine cardiovascular coronary disease heart disease heart failure heart health heart transplant heart hypertension medical medicine pericardial pharmacology pulmonary treatment tumor vascular |
| ISBN |
0-8135-7969-4
1-78684-765-5 0-8135-7970-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Front matter -- Contents -- Abbreviations -- Preface -- Acknowledgments -- 1. Statistics -- 2. General Cardiology -- 3. Physical Exam -- 4. EKG -- 5. Congenital Heart Disease -- 6. Valvular Heart Disease -- 7. Heart Failure/ Transplant -- 8. Acute Coronary Syndromes -- 9. Pericardial Disease -- 10. Electrophysiology -- 11. Pharmacology -- 12. Pregnancy -- 13. Pulmonary Hypertension -- 14. Peripheral Vascular Disease -- 15. Echocardiography -- 16. Interventional Cardiology -- 17. Cardiac Tumors -- 18. Formulas -- References -- Works Cited -- Index -- About The Author |
| Record Nr. | UNINA-9910819405303321 |
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Yeghiazarians Yerem
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| New Brunswick, NJ : , : Rutgers University Press, , [2017] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Immunotherapy, Tumor Microenvironment and Survival Signaling
| Immunotherapy, Tumor Microenvironment and Survival Signaling |
| Autore | Golubovskaya Vita |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (376 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
Autophagy
colorectal cancer immunotherapy tumor stroma tumor microenvironment immune checkpoint inhibitors chemotherapy tyrosine kinase inhibitors angiogenesis check point inhibitors programmed cell death protein 1 programmed cell death 1 ligand 1 cardiotoxicity lung metastasis CAR-T hypoxia tumor microenvironment CD19 BCMA cancer melanoma immune escape antigen loss chimeric antigen receptor electroporation lentivirus lentiviral transduction macrophages leukemia cells lytic peptides targeted therapy dendritic cells pathogenesis risk factors breast cancer resistance checkpoint targeted treatment personalized medicine pediatric solid tumors chimeric antigen receptors cancer vaccines oncolytic viral therapy immunomodulation DCLK1 tumor stem cells clonogenicity mitochondria mitochondrial transfer tunneling nanotubes triple-negative breast cancer immune checkpoint inhibitor combination therapy cancer nanomedicine tumor antigens cancer metabolism cancer immunotherapy nanoparticles immunotherapeutic agent immunomodulators tuft cells cancer stem cells immunotherapies myeloid-derived suppressor cells regulatory T cells crosstalk tumor immune evasion cell-cell contact β2 integrins CD18 CD11 CAR-T cells CD37 cell therapy tumor antigen lymphoma CAR macrophage CAR T cell solid tumors immunometabolism miRNA immunogenic cell death |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580205403321 |
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Golubovskaya Vita
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges
| Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges |
| Autore | Gabazza Esteban C |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (348 p.) |
| Soggetto non controllato |
bleomycin
regeneration antitumor efficacy lung cancer SOX2 leiomyosarcoma lung cancer (LC) nanoparticles cytokines hepatocellular carcinoma metabolic reprogramming hepatic stellate cells angiogenesis transforming growth factor-? anaplastic lymphoma kinase idiopathic pulmonary fibrosis growth factor pathogenesis cancer-associated fibroblasts fibrosis lipopolysaccharide DHA lncRNA SREBP-1 YAP protein S non-small cell lung cancer (NSCLC) omega-3 fatty acid inflammation metastasis clinical symptoms miRNA smooth muscle tumor of uncertain malignant potential Wnt interstitial fluid pressure heterogeneity hepatocytes myometrium tumor necrosis factor ? tumor tumor microenvironment extracellular matrix TAZ carcinogenesis cystic formation pulmonary fibrosis HBV cytokine genetic instability diagnosis EMT crizotinib Hippo pathway GPR120 marker HCV non-alcoholic steatohepatitis pathology common pathways apoptosis type I collagen GPR40 acute lung injury uterine fibroid renal injury pathophysiology reactive oxygen species immunohistochemistry SMAD butylidenephthalide leiomyoma cirrhosis Erk1/2 targeted therapy TGF-? mechanotransduction therapy breast cancer hepatocellular carcinoma (HCC) hepatic stellate cells (HSCs) idiopathic pulmonary fibrosis (IPF) cancer-associated fibroblasts (CAFs) cancer signal pathway tumor stiffness |
| ISBN | 3-03921-707-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Links between Fibrogenesis and Cancer |
| Record Nr. | UNINA-9910367745903321 |
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Gabazza Esteban C
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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mTOR Signaling in Metabolism and Cancer
| mTOR Signaling in Metabolism and Cancer |
| Autore | Huang Shile |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
mTOR
histone deacetylase prostate cancer integrins adhesion invasion cell metabolism T cells Foxp3 Acute Lymphoblastic leukemia targeted therapy metabolism cell signalling mTOR signalling head and neck cancer mutant genes biomarkers targeted therapies clinical trials cancers inhibitors photodynamic therapy PI3K Akt skin cancers phytochemicals melanoma basal cell carcinoma squamous cell carcinoma Merkel cell carcinoma TNBC eribulin PI3K/AKT/mTOR everolimus combination synergy mTOR signaling tissue regeneration neuron muscle liver intestine hematologic malignancies regulatory T cells tumor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557107203321 |
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Huang Shile
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Research about Biomechanics and Biomaterials Used in Hip, Knee and Related Joints
| Novel Research about Biomechanics and Biomaterials Used in Hip, Knee and Related Joints |
| Autore | Kretzer J. Philippe |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (358 p.) |
| Soggetto topico | Information technology industries |
| Soggetto non controllato |
electrocautery
titanium alloy cobalt-chrome alloy fatigue behavior biomechanical study Vertebral body replacement (VBR) non metallic radiolucent CF/PEEK biomechanics tumor vertebral fracture spine calcium phosphate granules bone graft substitutes total hip arthroplasty implant deformation acetabulum Metasul 28 mm small head metal-on-metal THA cobalt chromium titanium blood metal ions inflammation cytokines metal particles metal ions synovium dual taper modular hip stem acetabular revision asymptomatic stem modularity decision making model threshold biomaterials arthroplasty orthopaedic tribology experimental simulation total knee replacement PEEK-OPTIMA™ UHMWPE third body wear modular acetabular cup poly-ether-ether-ketone (PEEK) ceramics ultra-high-molecular-weight polyethylene (UHMW-PE) strain distribution bone stock cup-inlay stability disassembly forces relative motion periprosthetic joint infections infection prophylaxis Staphylococcus epidermidis in vivo osteomyelitis model metal wear retrieval study metal-on-metal articulation volumetric wear megaendoprosthesis total knee arthroplasty bone tumor Roentgen stereophotogrammetric analysis hip arthroplasty elementary geometrical shape model interchangeability head-taper junction migration ion implantation precision casting Ti6Al4V calcium phosphorus centrifugal casting porous implants tantalum hip replacement revision hip arthroplasty primary stability backside wear cross-linked total hip replacement hip cup system composite fibers polycarbonate-urethane meniscal replacement mechanical properties meniscus silicon nitride coating joint replacement wear adhesion trunnionosis trunnion failure fretting corrosion head-neck junction mechanically assisted crevice corrosion implant biomaterial corrosion residual stress taper connection anodic polarization surface treatment knee joint patellar component musculoskeletal multibody simulation patellofemoral joint polyetheretherketone fixation debonding implant-cement interface PMMA periprosthetic joint infection cement spacer articulating spacer hip spacer two-stage revision surface alteration surface roughness third-body wear zirconium oxide particles metal-on-cement articulation oxford unicompartmental knee arthroplasty bearing thickness retrieval analysis biomedical rheology viscosity bovine calf serum shear thinning numerical simulation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557308003321 |
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Kretzer J. Philippe
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oncolytic Virus Immunotherapy
| Oncolytic Virus Immunotherapy |
| Autore | Marchini Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (366 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
oncolytic viruses
melanoma immunotherapy checkpoint inhibitors combinatory therapy reovirus oncolytic virus adenovirus oncolytic virotherapy targeting immunogenic cell death αvβ6 integrin oncolytic adenovirus cancer immunotherapy multi-stage immunostimulatory arming HSV-1 clinical trials newcastle disease virus NDV cancer immune checkpoint inhibitor PD-1 PD-L1 CTLA-4 type I interferon herpes simplex virus retargeted virus tropism retargeting tumor checkpoint inhibitor vaccination antigen-agnostic vaccination HER2 parvovirus tumor microenvironment combination therapy glioblastoma pancreatic cancer colorectal cancer measles virus vector engineering immune checkpoint blockade antitumor immune response delivery genetic modification biomarkers personalized oncolyticvirotherapy class I HLA immunosurveillance immunoediting oncogenic signaling RAS DNA methyltransferase inhibitor (DNMTi) viral mimicry epigenetic silencing adoptive T cell therapy CAR T cell pancreatic ductal adenocarcinoma vesicular stomatitis virus small molecule cancer immune therapy cancer therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566462203321 |
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Marchini Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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