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Anticancer Agents : Design, Synthesis and Evaluation
| Anticancer Agents : Design, Synthesis and Evaluation |
| Autore | Chen Qiao-Hong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (606 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
1,2,3-triazole
2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide 3,6-dibromocarbazole 4-(pyridin-4-yloxy)benzamide 5-bromoindole 5-fluorouracil ABCB1 (P-glycoprotein) actin ADME allene amides/esters androgen receptor anti-cancer activity anti-neuroinflammation anti-ovarian cancer anti-tumor anticancer anticancer activity anticancer agent anticancer agents anticancer compounds antimitotic agents antioxidant activity antiproliferative activity antiproliferative agent antitumor antitumor activity apalutamide apoptosis aromatase benzimidazole benzofuran-pyrazole benzofurans beta-lapachone bivalency breast cancer c-Met carbazole cell cycle chemical synthesis chemoresistance chrysin analogues colchiceine colchicine amide colchicine analogs colchicine sulfonamide colon cancer computational docking coumarin crystal structure cyanopyridone cytotoxic activity cytotoxic properties cytotoxicity darolutamide DFT study dihydroartemisinin dihydropyranoindole docking docking studies drug discovery drug resistance E-stereoselective enzalutamide enzyme inhibition estrone derivatives flavonoid flavonoids gemcitabine HDAC inhibitors HeLa HepG2 hydrates hydrazine IGF-1R IL-12 immune modulation indoleamine 2,3-dioxygenase inflammation inhibitor K562 kinase inhibitor MCF-7 MDM2-p53 interaction migration mimetics molecular simulation MOLT-4 multidrug resistance (MDR) reversal N-substituted pyrazoline nanoparticles natural product neuroblastoma NIH3T3 o-nitro-benzyl organosilicon compounds ortho-quinones ovarian cancer overcoming drug resistance P-glycoprotein P-MAPA PARP inhibitor PARP-1 inhibition phenylpyrazolopyrimidine photoactivatable protecting groups PI3Ks PI3Kα inhibitor PI3Kδ inhibitors polyvalency prodrug prostate cancer PROTACs protein degradation protein kinase protein-protein interactions Pyrazole pyrazolopyridine pyridotriazine quinazolin-4(3H)-one quinazolin-4(3H)-thione regioselective salinomycin Schiff base SILA-409 (Alis-409) SILA-421 (Alis-421) Src substituted pyridine synergy synthesis Talazoparib tanshione IIA taxoids thiazolidinone Thienopyrimidine thienopyrimidinone thiocolchicine thiopene thioxotriazopyridine TLR signaling topoisomerase II inhibitor triazolothiadiazine triple-negative breast cancer tryptophan metabolism tubulin inhibitors tumor specificity urea virtual screening xanthones yeast-based assays zampanolide βIII-tubulin |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Anticancer Agents |
| Record Nr. | UNINA-9910557129103321 |
Chen Qiao-Hong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Biomarker Research and Personalized Medicine
| Cancer Biomarker Research and Personalized Medicine |
| Autore | Meehan James |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (428 p.) |
| Soggetto topico |
Medicine and Nursing
Oncology |
| Soggetto non controllato |
1H-NMR
Akt/mTOR AmpliSeq anastomotic leak autophagy bioinformatics biomarker biomarkers bladder tumor breast cancer cancer biomarkers cancer vaccine chemoradiotherapy chemoresistance chemotherapy circulating tumor cells clear cell renal cell carcinoma colorectal cancer comparative oncology CREB1 cytokine signalling DNA methylation drug perturbation epigenetics exosomes FOXO3 gastric cancer GBP5 glycopeptide gp130 haptoglobin head and neck cancer head and neck squamous cell carcinoma hepatocellular carcinoma HNSCC hormone-dependent carcinogenesis HPV genotyping IL13Rα2 IL6ST immune response intestinal anastomosis JAK2 LC-MS/MS lincRNA-p21 lipidomics lipoprotein lipase lipoprotein subfractions liquid biopsy liquid-based biomarkers localized prostate cancer long non-coding RNA lymph node metastasis lymphocyte-to-monocyte ratio mass spectrometry meta-analysis microRNA middle-up-down multiphasic multidetector computed tomography n/a One Health ovarian cancer p16 expression p53 peripheral blood parameters personalized medicine precision medicine predictive biomarker predictive tools prognostic factors prognostic tools prostate cancer radiomics radioresistance radiosensitivity biomarkers radiotherapy rectal cancer renal cell carcinoma saliva secretome taxane telmisartan tissue-based biomarkers translational research transurethral resection triple-negative breast cancer tumor recurrence WHO/ISUP nuclear grade |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674370003321 |
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Meehan James
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Immunotherapy, Tumor Microenvironment and Survival Signaling
| Immunotherapy, Tumor Microenvironment and Survival Signaling |
| Autore | Golubovskaya Vita |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (376 p.) |
| Soggetto topico |
Clinical and internal medicine
Medicine and Nursing |
| Soggetto non controllato |
angiogenesis
antigen loss Autophagy BCMA breast cancer cancer cancer immunotherapy cancer metabolism cancer nanomedicine cancer stem cells cancer vaccines CAR macrophage CAR T cell CAR-T CAR-T cells cardiotoxicity CD11 CD18 CD19 CD37 cell therapy cell-cell contact check point inhibitors checkpoint chemotherapy chimeric antigen receptor chimeric antigen receptors clonogenicity colorectal cancer combination therapy crosstalk DCLK1 dendritic cells electroporation hypoxia immune checkpoint inhibitor immune checkpoint inhibitors immune escape immunogenic cell death immunometabolism immunomodulation immunomodulators immunotherapeutic agent immunotherapies immunotherapy lentiviral transduction lentivirus leukemia cells lung metastasis lymphoma lytic peptides macrophages melanoma microenvironment miRNA mitochondria mitochondrial transfer myeloid-derived suppressor cells n/a nanoparticles oncolytic viral therapy pathogenesis pediatric solid tumors personalized medicine programmed cell death 1 ligand 1 programmed cell death protein 1 regulatory T cells resistance risk factors solid tumors targeted therapy targeted treatment triple-negative breast cancer tuft cells tumor tumor antigen tumor antigens tumor immune evasion tumor microenvironment tumor stem cells tumor stroma tunneling nanotubes tyrosine kinase inhibitors β2 integrins |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580205403321 |
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Golubovskaya Vita
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Pathways in Cancers
| Molecular Pathways in Cancers |
| Autore | Cristóbal Ion |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (284 p.) |
| Soggetto topico |
Medicine and Nursing
Oncology |
| Soggetto non controllato |
acetylation
actin cytoskeletal reorganization adaptive immunity advanced ovarian cancer anti-receptor therapy BET inhibitors biomarkers bladder cancer initiation breast cancer CALR cancer cancer immunology cancer therapeutics carcinogenicity CD99 agonist complement system DUSP1 EGFR dimerization endocytosis epigenetic epigenome epithelial cells FAK dephosphorylation genome glioblastoma gp120 hepatocellular carcinoma human immunodeficiency virus type 1 immune checkpoint inhibitors immune evasion immunotherapy innate immunity JAK2 luminal breast cancer MAPK matrix protein p17 metastasis metastatic melanoma methylation migration and invasion mitochondria molecular targeted agents MPL MS-determined phosphopeptides mTOR myeloproliferative neoplasms n/a Nef NIMA-related kinase 1 (NEK1) non-coding RNA OMD oncogenic signaling pathway ovarian cancer oxidative stress OXPHOS pancreatic ductal adenocarcinoma partial EMT patient survival pBRD4 PI3K PP2A PRELP prognosis prostate cancer PTPN12 Rac1 reactive oxygen species resistance reverse transcriptase RhoA SET signaling pathways small-cell lung cancer Snail splicing pathway TAK-228 Tat thioridazine (THD) tight junction tousled-like kinase (TLK) TPOR trastuzumab tripeptide triple negative breast cancer triple-negative breast cancer tumor immune microenvironment tumor microenvironment tumor suppression gene Warburg effect yes-associated protein 1 (YAP1) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566473703321 |
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Cristóbal Ion
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Natural Phenolic Compounds for Health, Food and Cosmetic Applications
| Natural Phenolic Compounds for Health, Food and Cosmetic Applications |
| Autore | Panzella Lucia |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (230 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
5,6-dihydroxyindole-2-carboxylic acid
açaí (Euterpe oleracea Mart.) acid hydrolysis agri-food waste analysis of variance (ANOVA) antibacterial antioxidant antioxidant activity antioxidant enzyme activity antioxidants apoptosis autophagy bioavailability blueberry juice-maltodextrins cannabidiol cannabidiol synthetic derivatives circular economy conservation of antioxidants controlled release correlation cross-linked hydrogel cytotoxic dimethyl carbonate DPPH assay electrospinning encapsulation endocannabinoids essential oil exhausted wood factorial design feijoa extracts flavonoids FRAP assay functional food gelatin ginsenosides glutathione green chemistry HaCaT cells heat stress heavy metals high shear homogenization homovanillyl alcohol HS-SPME/GC-MS-TOF hydroxytyrosol hydroxytyrosol-enriched extracts inflammation isoliquiritigenin (ISL) lipid peroxidation lipophilic alkyl esters maturation melanins melatonin membrane receptors mentha mercury methylene blue México n/a nanoparticle nanostructured lipid carriers (NLC) nitric oxides NMR Nrf-2 Olea europaea orange essential oil oxidative stress Panax quinquefolius phenolic acids photoprotection polyphenol propolis puffing reactive oxygen species red blood cells resveratrol salicylic acid solubility spray drying supercritical fluid tannins thiol groups triple-negative breast cancer tyrosol ultrasound method UVA volatile compounds xoconostle zein |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557628703321 |
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Panzella Lucia
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Anti-cancer Agents and Cellular Targets and Their Mechanism(s) of Action
| Novel Anti-cancer Agents and Cellular Targets and Their Mechanism(s) of Action |
| Autore | Allison Simon J |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (206 p.) |
| Soggetto topico |
History of engineering & technology
Technology: general issues |
| Soggetto non controllato |
5-FU resistance
8-hydroxydaidzein affibody drug conjugate (AffiDC) affibody molecule albumin binding domain angiogenesis anti-cancer agent anticancer drug apoptosis AQ4N autophagy B-lactam steroid alkylators BCR-ABL biomarker bioprecursor breast cancer BxPC-3 c-myc cancer hallmarks CCN1 colorectal cancer Connectivity Map CYP1A1 CYP1B1 CYP2W1 Cytochrome P450 DM1 drug repurposing duocarmycin EGFR tyrosine kinase inhibitor emtansine expression gene silencing Genomics of Drug Sensitivity in Cancer glioblastoma HepG2 Huh7 human epidermal growth factor receptor 3 (HER3) hybrid steroidal alkylating agents in vivo imaging invasion isatin sulfonamides K562 MAPK mesenchymal-amoeboid transition microtubule acetylation migration molecular docking n/a nanoparticles nanosystems NF-κB oncogene ovarian cancer phortress photon upconversion PLGA poly (ADP-ribose) polymerase inhibitors prodrug RNA interference siRNA synthetic lethality triple-negative breast cancer triplet-triplet annihilation |
| ISBN | 3-0365-5222-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Novel Anti-cancer Agents and Cellular Targets and Their Mechanism |
| Record Nr. | UNINA-9910619465503321 |
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Allison Simon J
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Developments in Cancer Systems Biology
| Recent Developments in Cancer Systems Biology |
| Autore | Sinha Raghu |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (272 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
acute myeloid leukemia
bioinformatics biomarker Boolean model brain-tumor-initiating cell (BTIC) breast cancer cancer genomics cancer progression cancer stem cells cancer systems biology circulating miR-1246 clinical trials CNV computational methods diagnostic biomarker differential expression docking drug repurposing drug resistance Elk-1 Ets ETS Ets-1 experimental model systems genomics glioma glycomics glycosaminoglycan binding knockdown lung adenocarcinoma lung adenocarcinoma (LUAD) lung cancer lung squamous cell carcinoma (LUSC) metabolomics metagenomics microarray n/a network next-generation sequencing non-small-cell lung cancer omics optical genome mapping ovarian pancreatic cancer patient survival patient-derived organoids patient-derived xenografts PEA3 personalized medicine PI3K-Akt signaling pathways prognosis prognostic biomarker protein interactome proteomics renal cancers risk group Sestrin2 signature single-cell sequencing SNV solid tumors stem cell survival systems biology TargetScan TCGA transcriptomics triple-negative breast cancer UBE2C virtual screening |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557768503321 |
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Sinha Raghu
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Special Issue Dedicated to Late Professor Takuo Okuda : : Tannins and Related Polyphenols Revisited: Chemistry, Biochemistry and Biological Activities / / Takashi Yoshida, Tsutomu Hatano, Hideyuki Ito
| Special Issue Dedicated to Late Professor Takuo Okuda : : Tannins and Related Polyphenols Revisited: Chemistry, Biochemistry and Biological Activities / / Takashi Yoshida, Tsutomu Hatano, Hideyuki Ito |
| Autore | Yoshida Takashi |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (316 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Coreopsis lanceolata L.
UV-Vis methanogenesis Lythraceae flavanone grape marc TDDFT Ephedra sinica macrocyclic oligomer triple-negative breast cancer antioxidant purple prairie clover chalcone neuraminidase fatty acid synthase (?)-epigallocatechin gallate epidermal growth factor NMR spectroscopy Aluminum ion Onagraceae Hydrangea macrophylla synthetic analogues blue color development amyloid-? peptide FTIR oseltamivir carboxylate quantitative NMR phloroglucinolysis thin layer chromatography European historic leathers FASN inhibition ECD colorimetric tests taxanes cynandione A conservation method 5-O-caffeoylquinic acid ellagitannin PC12 condensed tannin Trapa taiwanensis Nakai 1H-NMR Acacia (?)-epigallocatechin 3-gallate Geranium thunbergii condensed tannins immunomodulatory effect Acacia mearnsii bark Escherichia coli oligomer Horner–Wadsworth–Emmons reaction lung tumor Aspergillus fumigates in vitro batch fermentation metal complex Myrtaceae Cynanchum auriculatum molecular interactions phenolic glycoside bamboo leaf extract stability Microsporum canis Cynanchum wilfordii thiolysis anti-inflammation hydrolysable tannin geraniin NGF polyphenol revision ESI-mass bioactivity antifungal activities interferon-? antitumor effect tannin composition oenothein B zanamivir 2-O-?-laminaribiosyl-4-hydroxyacetophenone anticancer activity proanthocyanidin vegetable tanning Dittrichia viscosa differentiation aurone antioxidants protein precipitation apoptosis polyphenolic FASN inhibitors forage legume biological activities ultrahigh-resolution negative mode MALDI-TOF mass spectrometry overlay method spectroscopy wattle tannin immune checkpoint hormesis 3-O-glucosyldelphinidin gallotannin proanthocyanidins fatty acids flavonol inhibition structure Candida spp Malassezia spp ORAC assay neuroprotection crystal structure tannins |
| ISBN |
9783038978350
3038978353 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346671803321 |
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Yoshida Takashi
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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