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A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder
| A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder |
| Autore | Frye Richard E |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
fecal metabolites
ASD microbiome gastrointestinal symptoms Fisher Discriminant Analysis digital biomarkers wearables time series analysis autism social dyads socio-motor parameters network connectivity non-linear complex dynamics stochastic analysis autism spectrum disorders copy number variants females Array-Comparative Genomic Hybridization (Array-CGH) autism spectrum disorder Ehlers-Danlos syndrome hypermobility spectrum disorders autonomic disorder mast cell activation syndrome genetic testing chromosomal microarray analysis whole exome sequencing whole genome sequencing clinical utility polygenic risk scores Temple Grandin biomarker omics precision medicine proteomics transcriptomics epigenetics metabolomics patient stratification mitochondria oxidative stress prenatal environment immune dysfunction immunoglobulin G intravenous immunoglobulin energy metabolism fatty acid oxidation acyl-carnitines resveratrol integrative model concomitant condition disorder autism spectrum disorder (ASD) genomics personalized treatment strategy single nucleotide polymorphisms clinical decision support tool ADHD PANDAS OCD anxiety folate receptor alpha folates pregnancy brain development fetal development cobalamin glutathione methylation methylcobalamin redox metabolism locked-in network syndrome resting-state functional magnetic resonance imaging temporal lobe epilepsy amygdala brain COVID-19 children cytokines flavonoids inflammation luteolin mast cells microglia SARS-CoV-2 stress nutraceuticals survey vitamins minerals B12 folinic acid quality of life parents intervention systematic review medical claims logistic regression analysis retrospective analysis associated risk monoamine neurotransmitters neurotransmitter deficiency cerebral folate deficiency folate receptor alpha autoantibodies leucovorin α-amylase cortisol heart rate variability neuromodulation sleep anxiety transdermal electrical neuromodulation neurostimulation |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595075503321 |
Frye Richard E
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Molecular Breeding of Vegetable Crops
| Advances in Molecular Breeding of Vegetable Crops |
| Autore | Zhang Yuyang |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (242 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Technology, engineering, agriculture |
| Soggetto non controllato |
pepper
Capsicum annuum Phytophthora capsici high-density genetic map QTL Capcicum annuum L. RNA-Seq nitrogen-use efficiency low-nitrogen tolerance CaHSP18.1a gene silencing transgenic Arabidopsis heat stress gene expression pumpkin simple sequence repeat (SSR) syntenic relationship cross-species markers population structure eggplant heat shock factor (Hsf) heat shock protein (Hsp) thermotolerance C. frutescens SSR germplasm genetic diversity CRISPR/Cas gene knockout genome editing germplasm resource precision editing regulatory framework trait improvement Brassica oleracea broccoli candidate gene anthocyanin allelochemicals VOCs properties VOCs action VOCs detection green agriculture progress genetic researches molecular breeding transcriptomics transcription factor heritability genetic advance multi-trait selection principal component analysis HRM molecular marker phylogenetic analysis RNA sequencing SCAR SNP |
| ISBN | 3-0365-5790-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910637793303321 |
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Zhang Yuyang
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in the Biology of Phototrophic Bacteria
| Advances in the Biology of Phototrophic Bacteria |
| Autore | Imhoff Johannes F |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
phylogeny
photosynthetic reaction center proteins bacteriochlorophyll biosynthesis phototrophic purple bacteria evolution of anoxygenic photosynthesis iron-sulfur cluster isc genes suf genes antisense promoters OxyR IscR Irr anoxygenic phototrophic bacteria purple nonsulfur bacteria massive blooms pufM gene Rhodovulum phylogenomics bioerosion anoxygenic phototroph microbiome euendolith Rhodobacter capsulatus Rhodobacter sphaeroides photooxidative stress transcriptomics proteomics stress defense heliobacteria Heliorestis convoluta alkaliphilic bacteria soda lake bacteriochlorophyll g biological soil crust drylands niche partitioning nitrogen fixing cyanobacteria Alphaproteobacteria Rhodobacteraceae nitric oxide quorum sensing gene transfer agent motility Crp/Fnr Dnr RegA ChpT green sulfur bacteria syntrophy e-pili adhesion protein photosynthetic symbionts large multiheme cytochrome metagenomic binning genomes of photosynthetic bacteria glycine betaine biosynthesis ectoine biosynthesis osmotic adaptation phylogeny of osmolyte biosynthesis filamentous anoxygenic phototroph microbial mats hot springs metatranscriptomics energy metabolism carbon fixation aerobic anoxygenic phototrophic bacteria bacteriochlorophyll a photosynthesis genes rhodopsin Sphingomonadaceae aerobic anoxygenic phototrophs siderophore metallophore CAS assay Chromocurvus halotolerans strain EG19 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557401903321 |
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Imhoff Johannes F
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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An Evolutionary and Environmental Perspective of the Interaction of Nanomaterials with the Immune System-The Outcomes of the EU Project PANDORA
| An Evolutionary and Environmental Perspective of the Interaction of Nanomaterials with the Immune System-The Outcomes of the EU Project PANDORA |
| Autore | Boraschi Diana |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (218 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
innate immunity
infection microbiome survival nanomaterials nanoparticles copper earthworms Eisenia fetida cosmetic formulation cosmetic lifecycle hydrophobic compound nano-TiO2 nano safety marine invertebrate metabolomics avian pathogenic Escherichia coli nanovaccine outer membrane vesicles immune response broiler earthworm coelomocyte TiO2 nanoparticles reactive oxygen species lipid peroxidation alkaline comet assay phagocytosis apoptosis gene expression hemocytes Mytilus in vitro scanning electron microscopy innate memory Schistosoma mansoni monocytes macrophages vaccination gold nanoparticles cerium nanoparticles woodlice haemocyte environmental models human cells markers NPs testing immune system inflammation tolerance engineered nanomaterial (ENM) nanoparticle (NP) gold nanoparticle (AuNP) plant Arabidopsis thaliana plant growth stress response transcriptomics proteomics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576882703321 |
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Boraschi Diana
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioinformatics and Machine Learning for Cancer Biology
| Bioinformatics and Machine Learning for Cancer Biology |
| Autore | Wan Shibiao |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
tumor mutational burden
DNA damage repair genes immunotherapy biomarker biomedical informatics breast cancer estrogen receptor alpha persistent organic pollutants drug-drug interaction networks molecular docking NGS ctDNA VAF liquid biopsy filtering variant calling DEGs diagnosis ovarian cancer PUS7 RMGs CPA4 bladder urothelial carcinoma immune cells T cell exhaustion checkpoint architectural distortion image processing depth-wise convolutional neural network mammography bladder cancer Annexin family survival analysis prognostic signature therapeutic target R Shiny application RNA-seq proteomics multi-omics analysis T-cell acute lymphoblastic leukemia CCLE sitagliptin thyroid cancer (THCA) papillary thyroid cancer (PTCa) thyroidectomy metastasis drug resistance biomarker identification transcriptomics machine learning prediction variable selection major histocompatibility complex bidirectional long short-term memory neural network deep learning cancer incidence mortality modeling forecasting Google Trends Romania ARIMA TBATS NNAR |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595077403321 |
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Wan Shibiao
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational Methods for the Analysis of Genomic Data and Biological Processes
| Computational Methods for the Analysis of Genomic Data and Biological Processes |
| Autore | Gómez Vela Francisco A |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (222 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
HIGD2A
cancer DNA methylation mRNA expression miRNA quercetin hypoxia eQTL CRISPR-Cas9 single-cell clone fine-mapping power RNA N6-methyladenosine site yeast genome methylation computational biology deep learning bioinformatics hepatocellular carcinoma transcriptomics proteomics bioinformatics analysis differentiation Gene Ontology Reactome Pathways gene-set enrichment meta-analysis transcription factor binding sites genomics chilling stress CBF DREB CAMTA1 pathway text mining infiltration tactics optimization algorithm classification clustering microarray ensembles machine learning infiltration computational intelligence gene co-expression network murine coronavirus viral infection immune response data mining systems biology obesity differential genes expression exercise high-fat diet pathways potential therapeutic targets DNA N6-methyladenine Chou's 5-steps rule Convolution Neural Network (CNN) Long Short-Term Memory (LSTM) machine-learning chromatin interactions prediction genome architecture |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557129603321 |
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Gómez Vela Francisco A
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Genetics of Animal Health and Disease in Livestock
| Genetics of Animal Health and Disease in Livestock |
| Autore | Castiglioni Bianca |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto topico |
Research & information: general
Technology: general issues |
| Soggetto non controllato |
broiler
thermal manipulation antioxidant heat stress cold stress Bovine Viral Diarrhea Virus RNA-Seq Transcriptome analysis Holstein cattle sheep intersex whole-genome resequencing copy number variation forming mechanism dairy cattle diseases innate immune system metabolic stress microbiome mastitis bovine mammary epithelial cells inflammatory cytokines NF-κB signaling PRRs TLRs Piemontese breed arthrogryposis macroglossia genetic model TLR3 TLR4 TLR7 foals immunostimulation gene expression bovine mastitis JAK-STAT pathway JAK2 STATs SOCS3 immunity milk production DNA methylation high-fat diet rabbits next generation sequencing transcriptomics bioinformatics genome editing disease resistance livestock dairy cattle teat-end hyperkeratosis udder health somatic cell genetic correlation selection response Holstein Friesian cattle mastitis resistance candidate genes SNP selection next-generation sequencing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557697903321 |
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Castiglioni Bianca
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Integrative Multi-Omics in Biomedical Research
| Integrative Multi-Omics in Biomedical Research |
| Autore | Gerner Christopher |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (178 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
target identification
target validation label-free method for drugs anti-angiogenesis mechanism of action receptor tyrosine kinases curcumin natural products lipid lipidomics cardiac metaplasia Barrett's esophagus esophageal adenocarcinoma microbiota DNA sensing IFI16 cGAS innate immunity protein interactions virus-host interactions post-translational modifications mass spectrometry proteomics transcriptomics multi-omics multi-omics analysis study design bioinformatics machine learning analysis flow metabolomics planned myocardial infarction (PMI) myocardial infarction (MI) exercise heart cheminformatics batch variations eicosanoids fetal calf serum peroxisomes host-pathogen interactions secretome macrophages acute myeloid leukemia HL-60 cell line ATRA induced differentiation transcriptome proteome transcription factors key molecules regulatory pathway modelling SRM endometriosis inflammation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557769003321 |
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Gerner Christopher
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ion Channels as Marine Drug Targets
| Ion Channels as Marine Drug Targets |
| Autore | Sabatier Jean-Marc |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (134 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
conotoxin
Conus tulipa intraspecific variation venomics transcriptomics proteomics conantokins net hunting strategy nirvana cabal ion channel modulators marine anti-TB compounds PZA MTB latent TB sponges nicotinic chemotherapy paclitaxel taxane neuropathic pain α9α10 saxitoxin zetekitoxin AB voltage-gated sodium channel guanidine alkaloid bioactives conotoxins 2 Kv1 marine toxins modulators potassium channels sea anemone toxins TxVIA mammalian NaV channel selective inhibitor T-type CaV3.2 botulinum toxin A1 chitosan nanoparticles antiarrhythmics pharmacological models of arrhythmia electrically induced arrhythmia |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557396203321 |
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Sabatier Jean-Marc
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Islet Inflammation and Metabolic Homeostasis
| Islet Inflammation and Metabolic Homeostasis |
| Autore | Collier Jason |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (126 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
beta cell death
beta cell dysfunction beta cell failure ER stress hyperglycemia obesity oxidative stress saturated fatty acids beta cell hypofunction beta cell hyperfunction glucolipotoxicity low carbohydrate diet ketogenic diet insulin sensitivity pancreas islet of Langerhans proinflammatory cytokines NADPH oxidases Rac1 pancreatic beta cell diabetes β-cell macrophage islet cytokine insulin transcriptomics type 2 diabetes insulin resistance inflammation gut microbiome untargeted plasma metabolomics polyunsaturated fatty acids prostaglandins insulin secretion beta-cell function |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557767303321 |
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Collier Jason
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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