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Advance in the Treatment of Pediatric Leukemia
| Advance in the Treatment of Pediatric Leukemia |
| Autore | Handgretinger Rupert |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
acute lymphoblastic leukemia
pediatric advances diagnosis treatment immunotherapy bispecific T-cell engager (BiTE) BCP-ALL leukemia TRAIL antibody Fc-engineering xenograft CD19 juvenile myelomonocytic leukemia RAS signaling hematopoietic stem cell transplantation 5-azacitidine myelodysplastic/myeloproliferative disorders targeted therapy ADC antibody-drug conjugate pediatric leukemia ALL AML allogeneic stem cell transplantation acute myeloid leukemia minimal residual disease conditioning regimen alternative donors B-ALL DUX4 IKZF1 PAX5 Ph-like ZNF384 NUTM1 T-ALL NOTCH1 BCL11B transcriptome genome chronic myeloid leukemia CML tyrosine kinase inhibitor immunizations COVID-19 childhood acute lymphoblastic leukemia low-risk ALL risk-stratified treatment treatment related toxicity L-asparaginase acute pancreatitis polymorphism SNV ABCC4 CFTR other extramedullary relapse lymphoblastic leukemia children prognosis evolution of CAR T cells FDA-approved CAR products TcR versus CAR limitations and complications of CAR T cell therapy future directions of CAR T cell therapy |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576878903321 |
Handgretinger Rupert
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Compounds from Natural Products: Separation, Characterization and Applications
| Bioactive Compounds from Natural Products: Separation, Characterization and Applications |
| Autore | Vamanu Emanuel |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico |
Technology: general issues
Biotechnology |
| Soggetto non controllato |
in vitro callus
cell suspension and root cultures biologically active substances ecdysteroids HPLC 1H NMR spectra Rhaponticum carthamoides Chaga medicinal fungi biomass yield mathematical modeling response surface methodology bioreactor culture mycelium antioxidant activity gamma irradiation Fomes fomentarius mushroom DPPH flavonoids polyphenols urinary infection in vitro Escherichia coli antimicrobial yellow onion skins extraction multifunctional ingredients Ficus carica L. ultrasonic enzyme co-assisted aqueous two-phase extraction UPLC-QTOF-MS/MS identification lactic acid fermentation betalain carotenoids red pepper beetroot carrot drying heat treatment seaweeds bioactive compounds food safety consumer health Cannabis sativa L. cannabinoids hemp oil UHPLC-PDA validation Cnidoscolus aconitifolius inflammation croton oil HL-60 phenols differentiation apoptosis transcriptome natural products bacteria downstream processing antibiotics isolation secondary metabolites pharmacognosy bioprospecting U. lactuca non-toxic solvents phenolics uropathogenic herbal medicines plant extract bioactive molecules |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Bioactive Compounds from Natural Products |
| Record Nr. | UNINA-9910576876703321 |
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Vamanu Emanuel
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological Drivers Of Vector-Pathogen Interactions
| Biological Drivers Of Vector-Pathogen Interactions |
| Autore | Oliver Marino Rego Ryan |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (145 p.) |
| Soggetto topico |
Science: general issues
Infectious & contagious diseases |
| Soggetto non controllato |
vector
pathogen immunity transcriptome arthropod microbiome |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557227203321 |
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Oliver Marino Rego Ryan
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Celebrating 120 Years of Butantan Institute Contributions for Toxinology
| Celebrating 120 Years of Butantan Institute Contributions for Toxinology |
| Autore | Moura-Da-Silva Ana Maria |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (408 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
mass spectrometry
proteome snake venom Bothrops jararaca breast cancer HF3 human plasma proteolysis snake venom metalloproteinase Bothrops atrox blister local damage DAMPs antivenom snakebite Bothrops metalloproteases inflammation microcirculation adhesion molecules leukocyte-endothelium interactions individual variability venom heterogeneity STEC Stx2 antibody fragment monoclonal antibody neurodegenerative disease neurodegeneration IL-17 glial cells crotoxin epithelial-mesenchymal transition spheroid model tumor stroma Lonomia envenoming innovation Tityus serrulatus venom components hypotensins NEP inhibition cytokines toxins venoms skin secretion drug discovery scorpion accidents lactation maternal care seizure threshold leech Haementeria vizottoi cysteine proteases inhibitor recombinant cystatin cathepsin L Cryptops iheringi centipede venom toxin transcriptome recombinant protein venomics chilopoda oral tolerance ELISA Bothrops phospholipases A2 lipid mediators signaling pathways fish venoms cytolysins multifunctionality pore formation Bitis arietans venom (BaV) Kn-Ba cytokines and chemokines PGE2 THP-1 macrophages analgesic peptide protein kinase C hyperalgesia cell-signaling Hyalomma dromedarii salivary glands serpin anticoagulants thrombin inhibitor β-defensins snakes antimicrobial activity bioisosterism peptides Thalassophryne nattectin reverse-phase HPLC MALDI-ToF hemagglutinating activity antibacterial activity toxinology animal toxins |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674030303321 |
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Moura-Da-Silva Ana Maria
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Crop Breeding for Drought Resistance
| Crop Breeding for Drought Resistance |
| Autore | Luo Lijun |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (229 p.) |
| Soggetto topico |
Science: general issues
Botany & plant sciences |
| Soggetto non controllato |
drought-resistance
crop breeding genome-wide association study transcriptome phenotyping omics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557242003321 |
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Luo Lijun
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0
| Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0 |
| Autore | Dansette Patrick M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (286 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
Antibiotics
Bacillus biosynthetic gene clusters comparative analysis cytochrome P450 monooxygenase Mycobacterium P450 diversity percentage P450 profiling secondary metabolites NADPH-cytochrome P450 reductase (CPR) microsomal cytochrome P450 (CYP) Cytochrome b5 (CYB5) protein dynamics electron-transfer (ET) protein–protein interaction cytochromes P450 CYP3A4 active site access channels cavities boundaries minimal cost paths CYP139A1 genome data mining host metabolism Mycobacterium tuberculosis polyketides tuberculosis cryptococcus cryptococcus neoformans CYP51 fungal pathogens genome data-mining human pathogens CYP diversity analysis tremellomycetes trichosporon mechanism-based inhibitor crystal structure CYP4 genes genetic polymorphisms 20-HETE fatty acid arachidonic acid SNPs molecular functionality metabolism lamellar ichthyosis Bietti’s crystalline dystrophy cytochrome P450 isoform membrane protein protein-membrane interactions enzyme substrate specificity mutagenesis molecular dynamics simulation Sogatella furcifera sulfoxaflor transcriptome RNA interference CYP2C8 polymorphisms reactive oxygen species paclitaxel cytochrome P450 reductase electron transfer extracellular vesicles exosomes extrahepatic tissues plasma circulatory CYPs CYP450 drug metabolism precision Cardio-Oncology precision medicine systems medicine cytochromes P450 monooxygenases Cyanobacteria gene-cluster diversity percentage mathematical formula phylogenetic analysis Streptomyces cytochrome P450 monooxygenases terpenes P450 blooming non-ribosomal peptides cytochrome P450 monooxygenenases CYP128A1 Mycobacterium tuberculosis H37Rv molecular dynamic simulations azole drugs menaquinone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cytochromes P450 |
| Record Nr. | UNINA-9910557761103321 |
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Dansette Patrick M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Forest-Tree Gene Regulation in Response to Abiotic and Biotic Stress
| Forest-Tree Gene Regulation in Response to Abiotic and Biotic Stress |
| Autore | Herrington Gaya |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (180 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Forestry & related industries |
| Soggetto non controllato |
Ligustrum × vicaryi Rehd
aquaporin natural cold stress cold resistance drought stress waterlogging stress plant morphology physiology and biochemistry transcription factor bHLH transcription factor cold stress expression pattern genome-wide identification Liriodendron chinense Pinus massoniana aluminum stress transcriptomic WGCNA analysis phenylpropanoid biosynthesis R2R3-MYB Populus rust Melampsora larici-populina Larix kaempferi GRAS family genome-wide analysis phytohormone qRT-PCR Pinus massoniana Lamb AP2/ERF transcription factor bioinformatics exogenous hormone freezing stress apricot kernel transcriptome transcription factors ROS regulatory network miRNA Tilia tuan high-throughput sequencing seed maturation |
| ISBN | 3-0365-5948-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639999903321 |
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Herrington Gaya
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Functionally Relevant Macromolecular Interactions of Disordered Proteins
| Functionally Relevant Macromolecular Interactions of Disordered Proteins |
| Autore | Simon Istvan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (520 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
intrinsically disordered proteins
epiproteome disordered protein platform molecular recognition feature post-translational modifications physiological homeostasis stress response RIN4 p53 molecular machines intrinsically disordered protein membrane-less organelle neurodegenerative disease p300 HAT acetylation post-translational modification protein aggregation Tau fibrillation intrinsically disorder proteins disorder-to-order regions protein–RNA interactions unstructured proteins conformational plasticity disordered protein folding ribosomal protein spectroscopy protein stability temperature response protein thermostability salt bridges meta strategy dual threshold significance voting decision tree based artificial neural network protein intrinsic disorder intrinsic disorder intrinsic disorder prediction intrinsically disordered region protein conformation transcriptome RNA sequencing Microarray differentially regulated genes gene ontology analysis functional analysis intrinsically disordered structural disorder correlated mutations co-evolution evolutionary couplings residue co-variation interaction surface residue contact network dehydron homodimer hydrogen bond inter-subunit interaction ion pair mutual synergistic folding solvent-accessible surface area stabilization center MLL proteins MLL4 lncRNA HOTAIR MEG3 leukemia histone lysine methyltransferase RNA binding protein hydration wide-line 1H NMR secretion immune extracellular protein-protein interaction structural domain evolution transcription factors DNA-protein interactions Sox2 sequential DNA loading smFRET DNA conformational landscape sequential DNA bending transcription factor dosage oligomer N-terminal prion protein copper binding prion disease mutations Nuclear pore complex FG-Nups phosphorylation coarse-grained CABS model MC simulations statistical force fields protein structure intrinsically disordered proteins (IDPs) neurodegenerative diseases aggregation drugs drug discovery plant virus eIF4E VPg potyvirus molten globule fluorescence anisotropy protein hydrodynamics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557509403321 |
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Simon Istvan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Genetic and Morphological Variation in Tropical and Temperate Plant Species
| Genetic and Morphological Variation in Tropical and Temperate Plant Species |
| Autore | Kress W. John |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Forestry & related industries |
| Soggetto non controllato |
Hevea brasiliensis Müll. Arg
HbMad-box genes conserved domains gene structures expression profiles stress treatments microsatellite locus Hardy-Weinberg equilibrium genetic differentiation breeding population artificial selection Aegle marmelos (L.) Corr transcripts transcriptome assembly simple sequence repeats transcription factors cytochrome p450 glycotransferases metabolic pathway grafting pecan miRNA graft union sequencing edible forest product forest biology macro-fungi non-timber forest products (NTFPs) Pan-Pearl River Delta allometry anatomy Polygonatum odoratum Polygonatum multiflorum shape shoot endophytes medicinal plants pathogen molecular identification plant-microbe interaction gas exchange chlorophyll fluorescence growth trait genetic variation early selection pedunculate oak drought stress memory flushing autumn leaf senescence phenological shift carry-over effect mangroves DNA barcoding species identification phylogenetic relation moso bamboo heat shock factor gene abiotic stresses co-expression yellow-green leaf mutant transcriptome antenna protein photosynthesis birch Dalbergia odorifera T. Chen genetic diversity population structure EST-SSR marker microsatellite marker rosewood conservation Pinus massoniana introgression hybrid RNA sequencing DEGs reproduction phenology leafing out flowering senescence cumulative logistic regression hawthorn provenance trial non-local populations variance analysis lime application understory removal microbial community forest management Eucalyptus protogyny (PG) protandry (PA) pollen viability seed success polyploidy phosphate solubilizing bacteria nutrition oil tea Lagerstroemia species simple sequence repeat markers bulked segregant analysis creeping trait plant architecture climate change forest biodiversity plant–environment interactions plant traits urbanization |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674009403321 |
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Kress W. John
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Genetics and Improvement of Forest Trees
| Genetics and Improvement of Forest Trees |
| Autore | Ide Yuji |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (328 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
early selection
stomatal characteristics water stress water relations specific leaf area Eucalyptus clones LTR-retrotransposon Ty3-gypsy Ty1-copia IRAP molecular markers bamboo Phyllostachys genetic diversity populations structure AMOVA central-marginal hypothesis cline Pinaceae trailing edge population Sakhalin fir sub-boreal forest gibberellin male strobilus induction transcriptome conifer Cryptomeria japonica linkage map male sterility marker-assisted selection C. fortunei differentially expressed genes phenylpropanoid metabolism candidate genes Camellia oleifera leaf senescence transcriptome analysis senescence-associated genes physiological characterization cpDNA next generation sequencing northern limit nucleotide diversity phylogeny In/Del SNP SSR Chinese fir heartwood secondary metabolites widely targeted metabolomics flavonoids amplicon sequencing AmpliSeq genomic selection Japanese cedar (Cryptomeria japonica) multiplexed SNP genotyping spatial autocorrelation error pine wood disease resistance to pine wood nematode inoculation test multisite cumulative temperature Pinus thunbergii Thujopsis dolabrata EST-SSR markers varieties population structure pine wilt disease Bursaphelenchus xylophilus genotype by environment interaction Japanese black pine variance component local adaptation silviculture seed zone tree improvement program breeding genotype × environment interaction mast seeding seed production thinning forest tree breeding high-throughput phenotyping epigenetics genotyping genomic prediction models quantitative trait locus breeding cycle Cryptomeria japonica var. sinensis demographic history RAD-seq ancient tree conservation infrared thermography chlorophyll fluorescence cumulative drought stress genetic conservation genetic management pine wood nematode pine wood nematode-Pinus thunbergii resistant trees |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557345103321 |
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Ide Yuji
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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