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In Silico Strategies for Prospective Drug Repositionings
| In Silico Strategies for Prospective Drug Repositionings |
| Autore | Udrescu Lucreția |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
COVID-19
drug repurposing topological data analysis persistent Betti function SARS-CoV-2 network-based pharmacology combination therapy nucleoside GS-441524 fluoxetine synergy antidepressant natural compounds QSAR molecular docking drug repositioning UK Biobank vaccine LC-2/ad cell line drug discovery docking MM-GBSA calculation molecular dynamics cytotoxicity assay GWAS multiple sclerosis oxidative stress repurposing ADME-Tox bioinformatics complex network analysis modularity clustering ATC code hidradenitis suppurativa acne inversa transcriptome proteome comorbid disorder biomarker signaling pathway druggable gene drug-repositioning MEK inhibitor MM/GBSA Glide docking MD simulation MM/PBSA single-cell RNA sequencing pulmonary fibrosis biological networks p38α MAPK allosteric inhibitors in silico screening computer-aided drug discovery network analysis psychiatric disorders medications psychiatry mental disorders toxoplasmosis Toxoplasma gondii in vitro screening drug targets drug-disease interaction target-disease interaction DPP4 inhibitors lipid rafts |
| ISBN | 3-0365-6133-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639987703321 |
Udrescu Lucreția
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant-Based Bioactive Natural Products: Insights into Molecular Mechanisms of Action
| Plant-Based Bioactive Natural Products: Insights into Molecular Mechanisms of Action |
| Autore | Devkota Hari Prasad |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (170 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
foodborne diseases
giardiasis herbal drugs ethnobotany toxoplasmosis srophularia buergeriana cognitive impairment amyloid beta tau phosphorylation oxidative stress anti-apoptotic Terminalia chebula fruit osteoarthritis AyuFlex® cartilage collapse MMPs inflammation response vascular inflammation liensinine VSMC macrophage proliferation migration Nigella sativa methicillin-resistant Staphylococcus aureus synergism beta-lactam antibiotics artichoke by-products phenolic compounds HPLC-ESI-TOF-MS PLE GRAS Scrophularia buergeriana anti-amnesic effect cholinergic neurotransmission anti-oxidant anti-inflammation Vepris macropylla essential oil citral antiproliferative activity fluorescence and scanning electron microscopy human breast cancer cell line Vaccinium species phytochemicals berry leaf anti-inflammatory pathways endothelial dysfunction natural products bioactive compounds medicinal plants bioactivity mechanism of action traditional medicines |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Plant-Based Bioactive Natural Products |
| Record Nr. | UNINA-9910557350303321 |
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Devkota Hari Prasad
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Translational Research for Zoonotic Parasites: New Findings toward Improved Diagnostics, Therapy and Prevention
| Translational Research for Zoonotic Parasites: New Findings toward Improved Diagnostics, Therapy and Prevention |
| Autore | Colella Vito |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (284 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
canine vector-borne disease
blocking primers blood DNA extraction next-generation sequencing kit contaminant bacteria mosquito-borne disease pest control insecticide resistance biological control paratransgenesis Wolbachia Asaia Bacillus Strongyloides stercoralis soil-transmitted helminths hookworms zoonotic parasites Australian remote communities One Health biting midges vector mitochondrial cytochrome oxidase subunit I C. gornostaevae C. griseidorsum C. pallidicornis onchocerciasis Onchocerca volvulus antibodies diagnosis OV16 testing microfilariae epilepsy Dirofilaria immitis modified Knott's test ELISA immune complex dissociation serological assays bacterial profile cox1 Haemaphysalis bancrofti Ixodes holocyclus Ixodes trichosuri Ixodes tasmani V3-V4 16S rRNA gene mosquito virome CRESS-DNA viruses CyCV-VN insect-specific viruses ISV BatCV Leishmania protozoan parasite epidemiology environment Toxocara multiple sclerosis association meta-analysis Transphlebotomus Central Europe autoimmunofluorescence MALDI-TOF mass spectrometry genotyping leishmaniasis Polygonum salicifolium chalcone flavanone Leishmania mexicana Trypanosoma brucei brucei Trypanosoma congolense Canis lupus Vulpes vulpes Sarcoptes scabiei PCR serology Iberian Peninsula toxoplasmosis animals native antigens recombinant antigens Echinococcus NaOH LAMP DNA extraction taeniid egg isolation schistosomiasis Schistosoma japonicum right open reading frame protein kinase (riok) genes riok-1 RIOK-1 double-stranded RNA interference (RNAi) chemical inhibition toyocamycin developmental and reproductive biology blood filter paper Chagas disease Nobuto strip Trypanosoma cruzi mammalian surveillance neglected tropical diseases Culex pipiens s. l. Culex torrentium Culiseta glaphyroptera caves subterranean environment Luxembourg Germany |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Translational Research for Zoonotic Parasites |
| Record Nr. | UNINA-9910557894503321 |
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Colella Vito
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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