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In Silico Strategies for Prospective Drug Repositionings
| In Silico Strategies for Prospective Drug Repositionings |
| Autore | Udrescu Lucreția |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
COVID-19
drug repurposing topological data analysis persistent Betti function SARS-CoV-2 network-based pharmacology combination therapy nucleoside GS-441524 fluoxetine synergy antidepressant natural compounds QSAR molecular docking drug repositioning UK Biobank vaccine LC-2/ad cell line drug discovery docking MM-GBSA calculation molecular dynamics cytotoxicity assay GWAS multiple sclerosis oxidative stress repurposing ADME-Tox bioinformatics complex network analysis modularity clustering ATC code hidradenitis suppurativa acne inversa transcriptome proteome comorbid disorder biomarker signaling pathway druggable gene drug-repositioning MEK inhibitor MM/GBSA Glide docking MD simulation MM/PBSA single-cell RNA sequencing pulmonary fibrosis biological networks p38α MAPK allosteric inhibitors in silico screening computer-aided drug discovery network analysis psychiatric disorders medications psychiatry mental disorders toxoplasmosis Toxoplasma gondii in vitro screening drug targets drug-disease interaction target-disease interaction DPP4 inhibitors lipid rafts |
| ISBN | 3-0365-6133-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639987703321 |
Udrescu Lucreția
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Plant-Based Bioactive Natural Products: Insights into Molecular Mechanisms of Action
| Plant-Based Bioactive Natural Products: Insights into Molecular Mechanisms of Action |
| Autore | Devkota Hari Prasad |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (170 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
amyloid beta
anti-amnesic effect anti-apoptotic anti-inflammation anti-inflammatory pathways anti-oxidant antibiotics antiproliferative activity artichoke by-products AyuFlex® berry beta-lactam bioactive compounds bioactivity cartilage collapse cholinergic neurotransmission citral cognitive impairment endothelial dysfunction essential oil ethnobotany fluorescence and scanning electron microscopy foodborne diseases giardiasis GRAS herbal drugs HPLC-ESI-TOF-MS human breast cancer cell line inflammation response leaf liensinine macrophage mechanism of action medicinal plants methicillin-resistant migration MMPs natural products Nigella sativa osteoarthritis oxidative stress phenolic compounds phytochemicals PLE proliferation Scrophularia buergeriana srophularia buergeriana Staphylococcus aureus synergism tau phosphorylation Terminalia chebula fruit toxoplasmosis traditional medicines Vaccinium species vascular inflammation Vepris macropylla VSMC |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Plant-Based Bioactive Natural Products |
| Record Nr. | UNINA-9910557350303321 |
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Devkota Hari Prasad
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Translational Research for Zoonotic Parasites: New Findings toward Improved Diagnostics, Therapy and Prevention
| Translational Research for Zoonotic Parasites: New Findings toward Improved Diagnostics, Therapy and Prevention |
| Autore | Colella Vito |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (284 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
animals
antibodies Asaia association Australian remote communities autoimmunofluorescence Bacillus bacterial profile BatCV biological control biting midges blocking primers blood DNA extraction blood filter paper C. gornostaevae C. griseidorsum C. pallidicornis canine vector-borne disease Canis lupus caves Central Europe Chagas disease chalcone chemical inhibition cox1 CRESS-DNA viruses Culex pipiens s. l. Culex torrentium Culiseta glaphyroptera CyCV-VN developmental and reproductive biology diagnosis Dirofilaria immitis DNA extraction double-stranded RNA interference (RNAi) Echinococcus ELISA environment epidemiology epilepsy flavanone genotyping Germany Haemaphysalis bancrofti hookworms Iberian Peninsula immune complex dissociation insect-specific viruses insecticide resistance ISV Ixodes holocyclus Ixodes tasmani Ixodes trichosuri kit contaminant bacteria LAMP Leishmania Leishmania mexicana leishmaniasis Luxembourg MALDI-TOF mass spectrometry mammalian surveillance meta-analysis microfilariae mitochondrial cytochrome oxidase subunit I modified Knott's test mosquito virome mosquito-borne disease multiple sclerosis n/a NaOH native antigens neglected tropical diseases next-generation sequencing Nobuto strip Onchocerca volvulus onchocerciasis One Health OV16 testing paratransgenesis PCR pest control Polygonum salicifolium protozoan parasite recombinant antigens right open reading frame protein kinase (riok) genes riok-1 RIOK-1 Sarcoptes scabiei Schistosoma japonicum schistosomiasis serological assays serology soil-transmitted helminths Strongyloides stercoralis subterranean environment taeniid egg isolation Toxocara toxoplasmosis toyocamycin Transphlebotomus Trypanosoma brucei brucei Trypanosoma congolense Trypanosoma cruzi V3-V4 16S rRNA gene vector Vulpes vulpes Wolbachia zoonotic parasites |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Translational Research for Zoonotic Parasites |
| Record Nr. | UNINA-9910557894503321 |
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Colella Vito
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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