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Celebrating 120 Years of Butantan Institute Contributions for Toxinology
| Celebrating 120 Years of Butantan Institute Contributions for Toxinology |
| Autore | Moura-Da-Silva Ana Maria |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (408 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
mass spectrometry
proteome snake venom Bothrops jararaca breast cancer HF3 human plasma proteolysis snake venom metalloproteinase Bothrops atrox blister local damage DAMPs antivenom snakebite Bothrops metalloproteases inflammation microcirculation adhesion molecules leukocyte-endothelium interactions individual variability venom heterogeneity STEC Stx2 antibody fragment monoclonal antibody neurodegenerative disease neurodegeneration IL-17 glial cells crotoxin epithelial-mesenchymal transition spheroid model tumor stroma Lonomia envenoming innovation Tityus serrulatus venom components hypotensins NEP inhibition cytokines toxins venoms skin secretion drug discovery scorpion accidents lactation maternal care seizure threshold leech Haementeria vizottoi cysteine proteases inhibitor recombinant cystatin cathepsin L Cryptops iheringi centipede venom toxin transcriptome recombinant protein venomics chilopoda oral tolerance ELISA Bothrops phospholipases A2 lipid mediators signaling pathways fish venoms cytolysins multifunctionality pore formation Bitis arietans venom (BaV) Kn-Ba cytokines and chemokines PGE2 THP-1 macrophages analgesic peptide protein kinase C hyperalgesia cell-signaling Hyalomma dromedarii salivary glands serpin anticoagulants thrombin inhibitor β-defensins snakes antimicrobial activity bioisosterism peptides Thalassophryne nattectin reverse-phase HPLC MALDI-ToF hemagglutinating activity antibacterial activity toxinology animal toxins |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674030303321 |
Moura-Da-Silva Ana Maria
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Clostridioides difficile Infection
| Clostridioides difficile Infection |
| Autore | Granata Guido |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (178 p.) |
| Soggetto topico |
Medicine
Epidemiology & medical statistics |
| Soggetto non controllato |
Clostridioides difficile infection
co-morbidities mortality malignancy outcome risk factors C. difficile infection molecular analysis toxin production antibiotic resistance microbiome C. difficile hamsters bovine immunoglobulins 16S rRNA next generation sequencing Clostridioides difficile Charlson comorbidity index Child-Pugh score Clostridioides difficile associated disease CDI nonalcoholic fatty liver disease NAFLD NASH recurrent disease antibacterial Clostridioides (Clostridium) difficile peptidomimetic triazole baicalin gut dysbiosis mouse model spores anti-spore spore germination nanomaterial teicoplanin spore antibiotics multi-step algorithm multiplex "real-time" PCR PCR capillary-based electrophoresis ribotyping Clostridium difficile TcdA TcdB toxin toxemia plasma method quantification CDI severity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566483503321 |
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Granata Guido
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Bioactive Peptides : : Structure, Function, and Therapeutic Potential / / Tatiana V. Ovchinnikova
| Marine Bioactive Peptides : : Structure, Function, and Therapeutic Potential / / Tatiana V. Ovchinnikova |
| Autore | Ovchinnikova Tatiana V |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI, , 2019 |
| Descrizione fisica | 1 electronic resource (442 p.) |
| Soggetto non controllato |
cone snail
tilapia animal models BRICHOS domain recombinant peptide calcium absorption plastein reaction antioxidant activity endothelial dysfunction C3a lung cancer invertebrate immunity identification zinc bioavailability NA-inhibitory peptide nuclear magnetic resonance (NMR) review ACE-inhibitory activity intestinal absorption hairtail (Trichiurus japonicas) DU-145 cells peptide crustacean venom duct Kalloconus drug design molecular symmetry arenicin ?-helix APETx2 conotoxins functional diversity docking conotoxin neuraminidase angiotensin II polychaeta influenza virus phylogeny gene expression host defense peptide Perinereis aibuhitensis anti-diabetic activity conopeptides SHRs Chlorella pyrenoidosa protein hydrolysate (CPPH) metastasis Caco-2 cell monolayer Nrf2 caco-2 cells HUVEC PYP15 sea cucumber decapeptide cytotoxic arenicin-1 marine peptides cell proliferation Conus Conus ateralbus self-production of hydrogen peroxide antimicrobial activity molecular dynamics machine learning tachyplesins ion channels gut microbiota Anthopleura anjunae oligopeptide signaling pathways half-fin anchovy hydrolysates NF-?B Chlorella pyrenoidosa protein hydrolysate-calcium chelate (CPPH-Ca) antihypertensive effect QAGLSPVR antimicrobial peptides vasculogenic mimicry antibacterial ?-hairpin innate immunity transcriptome sequencing HIF-1? Gracilariopsis lemaneiformis function ACE-inhibitory peptide complement peptide-zinc complex structure-activity relationship multi-functional peptides cod skin adsorption Maillard reaction products molecular docking antibacterial peptide PI3K/AKT/mTOR signaling pathway Arenicola marina antimicrobial peptide Rana-box acid-sensing ion channel Neptunea arthritica cumingii apoptosis membrane damage proteolytic system toxin polyphemusins computational studies muscle oyster zinc-binding peptide abalone pain relief transport routes cytotoxicity dexamethasone cell death host?microbe relationship anti-LPS factor MMPs protein synthesis structure Pyropia yezoensis peptide cone snails chemical synthesis prostate cancer Ugr 9-1 myotube atrophy |
| ISBN |
9783039215331
3039215337 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367750603321 |
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Ovchinnikova Tatiana V
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| Basel, Switzerland : , : MDPI, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Bioactive Peptides II: Structure, Function, and Therapeutic Potential
| Marine Bioactive Peptides II: Structure, Function, and Therapeutic Potential |
| Autore | Ovchinnikova Tatiana V |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (228 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Spanish mackerel (Scomberomorous niphonius)
muscle peptide antioxidant activity stability biological activity chemistry marine derived fungi peptides biotransformation laxaphycin autophagy apoptosis cyanobacteria bioactive peptides marine secondary structure proline mechanism of activity marine waste antimicrobial peptide polychaeta innate immunity BRICHOS domain recombinant peptide β-hairpin structure nuclear magnetic resonance (NMR) arenicin complement system complement regulation jellyfish Rhopilema esculentum Sanderia malayensis proteome venom toxin hydrolysate fish protein ageing physical function dietary assessment seafood intake healthy ageing marine organism anticancer medicine small peptide liner peptide cyclic peptide marine peptide dolastatin 10 antitumor lead exploration |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Marine Bioactive Peptides II |
| Record Nr. | UNINA-9910557353303321 |
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Ovchinnikova Tatiana V
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nanobody
| Nanobody |
| Autore | Rothbauer Ulrich |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Bacillus anthracis
immunoassay single-domain antibody genetic fusion Beta galactosidase P-type ATPase nanobody llama Zinc-transport Zinc-transporting P-ATPase ZntA TNF fluorescent nanobodies sensor anti-cytokine therapy autoimmune disease Western equine encephalitis virus MagPlex toxin antibody camelid vaccine biodefense hydrogen exchange-mass spectrometry virus formatting Fc-domain half-life ischemia stroke MCAO single domain antibodies phage display intrabody intracellular antibody GTPase RHO BRET RAS chromobodies live-cell imaging compound screening cellular models single-domain antibody fragments molecular imaging molecular therapy nuclear imaging targeted fluorescence imaging intraoperative imaging Nanobody Single Domain Antibody Cancer Immunotherapy Imaging influenza influenza B virus hemagglutinin single domain antibody NanobodyTM yeast display epitope mapping GFP C. elegans development drosophila zebrafish targeted photodynamic therapy hepatocyte growth factor receptor HGFR c-Met Met VHH photosensitizer single-domain antibodies neurodegenerative diseases brain imaging blood-brain barrier delivery Aids HIV Llama Antibodies bi-specific VHH pepscan competition studies co-crystallisation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557147503321 |
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Rothbauer Ulrich
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The nature of nutrition [[electronic resource] ] : a unifying framework from animal adaptation to human obesity / / Stephen J. Simpson and David Raubenheimer
| The nature of nutrition [[electronic resource] ] : a unifying framework from animal adaptation to human obesity / / Stephen J. Simpson and David Raubenheimer |
| Autore | Simpson Stephen J |
| Edizione | [Course Book] |
| Pubbl/distr/stampa | Princeton, : Princeton University Press, 2012 |
| Descrizione fisica | 1 online resource (260 p.) |
| Disciplina | 612.3 |
| Altri autori (Persone) | RaubenheimerDavid <1960-> |
| Soggetto topico |
Nutrition
Nutrition - Research Animal nutrition Adaptation (Physiology) Bioenergetics Physiology, Experimental Obesity Energy metabolism |
| Soggetto non controllato |
Geometric Framework
aging agricultural animals animal feeds animal life animal nutrition applied nutrition biophysical ecology cannibalism companion animals conservation ecology dietary recommendations dietary restriction ecological communities ecological sciences ecosystem dynamics ecosystem endangered species energetic expenditure epigenetic effects evolutionary ecology feeding behavior food components food composition food requirements food webs food-level analysis geometric responses group-level behavioral patterns growth targets gut health human diet human health human nutrition human obesity imbalanced diets immune response individual nutrition individual nutritional state intake target intake targets life history theory life span life-history strategies lifespan local nutritional interactions macronutrient intake macronutrient malnutrition medicine metabolic disease metabolic responses micronutrient migration modern human diet multiple nutrients multiple-food-components natural medicines natural selection nutrient intake nutrient needs nutrient space nutrient-level analysis nutrients nutrition nutritional biology nutritional environment nutritional environments nutritional epigenetics nutritional geometry nutritional homeostasis nutritional immunology nutritional interactions nutritional regimes nutritional requirements nutritional sciences nutritional space nutritional state nutritional traits physiological responses postingestive regulatory responses protein appetite protein intake reproduction reproductive senescence self-medication sex sexual selection theory stored fat superorganism taste receptors toxin trophic dynamics |
| ISBN |
1-280-49403-4
9786613589262 1-4008-4280-8 |
| Classificazione | ZE 40000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Frontmatter -- Contents -- Acknowledgments -- One. Nutrition and Darwin's Entangled Bank -- Two. The Geometry of Nutrition -- Three. Mechanisms of Nutritional Regulation -- Four. Less Food, Less Sex, Live Longer? -- Five. Beyond Nutrients -- Six. Moving Targets -- Seven. From Individuals to Populations and Societies -- Eight. How Does Nutrition Structure Ecosystems? -- Nine. Applied Nutrition -- Ten. The Geometry of Human Nutrition -- Eleven. Perspectives -- References -- Index |
| Record Nr. | UNINA-9910779267703321 |
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Simpson Stephen J
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| Princeton, : Princeton University Press, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Ribosome Inactivating Toxins / Daniel Gillet, Julien Barbier
| Ribosome Inactivating Toxins / Daniel Gillet, Julien Barbier |
| Autore | Gillet Daniel |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI, , 2019 |
| Descrizione fisica | 1 electronic resource (329 p.) |
| Soggetto non controllato |
toxin
Shiga toxin ricin Ribosome inactivating protein |
| ISBN |
9783038972495
3038972495 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346668603321 |
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Gillet Daniel
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| Basel, Switzerland : , : MDPI, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of TCTP in Cell Biological and Disease Processes
| Role of TCTP in Cell Biological and Disease Processes |
| Autore | Bommer Ulrich-Axel |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (150 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Loxosceles
brown spider TCTP venom toxin HRF allergy mast cells basophils IgE FcεRI translationally controlled tumor protein (TCTP) apoptosis conditional knockout mice development Nestin-cre neurogenesis neuronal progenitor cells perinatal death proliferation Mmi1 translationally controlled tumor protein autophagy reactive oxygen species rapamycin nitrogen starvation cancer phospho-TCTP DHA T-DM1 HER2-positive breast cancer TCTP (HRF fortilin) growth and development biological stress reactions regulation of protein synthesis regulated protein degradation cardiovascular diseases |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674395803321 |
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Bommer Ulrich-Axel
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Toxin-Antitoxin Systems in Pathogenic Bacteria
| Toxin-Antitoxin Systems in Pathogenic Bacteria |
| Autore | Alonso Juan Carlos |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (170 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tuberculosis
toxin-antitoxin systems bacterial cell death NAD+ stress-response toxin-antitoxin system mazF type II toxin mRNA interferase X-ray crystallography cognate interactions cross-interactions molecular insulation antitoxin TA systems addiction anti-addiction type I toxin-antitoxin system small protein toxin structure Fst/Ldr family toxin-antitoxin M. tuberculosis bacteria pathogenesis protein-protein interactions cross-talk protein interface tolerance persistence cross-resistance PemI/PemK Klebsiella pneumoniae toxin activation antibacterial agents bacterial persistence Stenotrophomonas maltophilia opportunistic pathogen clinical origin environmental origin biofilm antibiotic resistance cell wall inhibition nucleotide hydrolysis uridine diphosphate-N-acetylglucosamine |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674020103321 |
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Alonso Juan Carlos
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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