Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Brain-Targeted Drug Delivery
| Brain-Targeted Drug Delivery |
| Autore | Sousa Flávia |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (260 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
3D cell culture systems
acetaminophen Alzheimer's disease Alzheimer's disease-relevant tau species anti-tau and anti-receptor bispecific monoclonal antibodies blood-brain barrier brain biodistribution brain cancer brain targeted therapy central composite rotatable design cerebral open flow microperfusion cerebrospinal fluid microcirculation chemoattractant claudin-5 CNS drug delivery convection-enhanced delivery CXCL CXCR delivery to brain depression diffuse midline glioma drug delivery drug delivery into the brain electrochemical biosensors GB-13 gene therapy glioblastoma glioblastoma multiforme glycol chitosan high-grade glioma hyaluronidase IL-13 IL-13Rα2 IL13.E13K-PE4E immunotherapy immunotoxin improved memory interactions between Aβ and tau intranasal delivery laser liposome macromolecules memory impairment microdialysis microparticles movement impairment n/a nanoparticle nanoparticles nanostructured lipid carrier naringenin nasal delivery system neurosurgery non-human primate nose to brain delivery opioids optogenetics Parkinson's disease phospholipid oily gel PLGA polyplexes pomegranate seed oil receptor expression seizure targeted therapy tau clearance in microglia tau clearance in neurons temporal-spatial pathological Aβ and tau distribution tight junction tolcapone transendothelium based on receptor-mediated transcytosis ultrasound |
| ISBN | 3-0365-5281-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619467203321 |
Sousa Flávia
|
||
| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular Pathways in Cancers
| Molecular Pathways in Cancers |
| Autore | Cristóbal Ion |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (284 p.) |
| Soggetto topico |
Medicine and Nursing
Oncology |
| Soggetto non controllato |
acetylation
actin cytoskeletal reorganization adaptive immunity advanced ovarian cancer anti-receptor therapy BET inhibitors biomarkers bladder cancer initiation breast cancer CALR cancer cancer immunology cancer therapeutics carcinogenicity CD99 agonist complement system DUSP1 EGFR dimerization endocytosis epigenetic epigenome epithelial cells FAK dephosphorylation genome glioblastoma gp120 hepatocellular carcinoma human immunodeficiency virus type 1 immune checkpoint inhibitors immune evasion immunotherapy innate immunity JAK2 luminal breast cancer MAPK matrix protein p17 metastasis metastatic melanoma methylation migration and invasion mitochondria molecular targeted agents MPL MS-determined phosphopeptides mTOR myeloproliferative neoplasms n/a Nef NIMA-related kinase 1 (NEK1) non-coding RNA OMD oncogenic signaling pathway ovarian cancer oxidative stress OXPHOS pancreatic ductal adenocarcinoma partial EMT patient survival pBRD4 PI3K PP2A PRELP prognosis prostate cancer PTPN12 Rac1 reactive oxygen species resistance reverse transcriptase RhoA SET signaling pathways small-cell lung cancer Snail splicing pathway TAK-228 Tat thioridazine (THD) tight junction tousled-like kinase (TLK) TPOR trastuzumab tripeptide triple negative breast cancer triple-negative breast cancer tumor immune microenvironment tumor microenvironment tumor suppression gene Warburg effect yes-associated protein 1 (YAP1) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566473703321 |
|
Cristóbal Ion
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular Research of Endometrial Pathophysiology / Paola Viganò, Andrea Romano
| Molecular Research of Endometrial Pathophysiology / Paola Viganò, Andrea Romano |
| Autore | Viganò Paola |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (378 p.) |
| Soggetto non controllato |
endometrial stromal cells
endometrial cell uterine cancer regeneration stem cell markers RANK chronic endometritis small RNA sequencing HOXA10 Vitamin D PPP2R1A molecular marker translational research angiogenesis endometriosis oestradiol mtDNA mutations antioxidant response protein phosphatase SMAP circulating tumour cells (CTCs) circulating tumour DNA (ctDNA) estrogen dependent endometrial regeneration mesenchymal stem cells endometrial cancer niche gene expression phosphoinositide 3-kinase lncRNAs mitochondrial biogenesis inflammation preclinical studies miRNA orthoxenograft tight junction proliferation aromatase testosterone CRISPR/Cas9 endometrium developmental pathway PP2A avatar infertility prognosis gene editing kinase inhibitor implantation haploinsufficiency contrast-enhanced CT scan pathway dehydroepiandrosterone (DHEA) CTCF PIK3CB zinc finger ectopic stroma liquid biopsy type II endometrial carcinoma eutopic and ectopic endometrium preclinical models EDN1 uterine aspirate cell contacts tumour suppressor gene pathogenomics mitochondrial dynamics adult stem cells PIK3CA murine models menstrual cycle immunomodulation decidualisation breakdown bioluminescence imaging protein kinase macrophages adherens junction exosomes immunohistochemistry orthotopic xenograft model decidualization p110? deficit of complex I targeted therapy mesenchymal stem cell sulfatase TRP channels personalized medicine mitophagy miR-375 migration microRNA gap junction cancer LGR5 miR-139-5p |
| ISBN |
9783039214969
3039214969 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367752903321 |
|
Viganò Paola
|
||
| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Sodium Intake and Related Diseases
| Sodium Intake and Related Diseases |
| Autore | Strazzullo Pasquale |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (90 p.) |
| Soggetto topico |
Biology, life sciences
Food & society Research & information: general |
| Soggetto non controllato |
ambulatory heart failure
blood pressure cardiovascular risk ENaC epidemiological studies heart failure high potassium hypertension inflammation leaky epithelia mineralocorticoid receptor mortality MST3 n/a Na+ cotransport NKCC2 OSR1 prognosis Rac1 renal injury salt salt intake salt-sensitive hypertension sodium SPAK STK24 tight junction WNK4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566468003321 |
|
Strazzullo Pasquale
|
||
| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The Tight Junction and Its Proteins : More Than Just a Barrier
| The Tight Junction and Its Proteins : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (432 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
actomyosin
adherens junction adherens junctions aging AMP-activated protein kinase (AMPK) angubindin-1 angulin anhidrosis antibiotic-associated hemorrhagic colitis antibody antidiuretic hormone apical junctional complex apoptosis aquaporin arachnoid barrier atopic dermatitis atypical aPKCζ barrier formation barrier function biliary epithelial cells blood-biliary barrier blood-brain barrier blood-cerebrospinal fluid barrier brain barriers calcium permeability Campylobacter jejuni cancer caspase CaSR celiac disease cell growth cell polarity cell-cell contact cerebral cavernous malformation chemoresistance cholangiocellular carcinoma cholestasis chronic liver disease claudin Claudin claudin 1 claudin targeting claudin-1 claudin-12 Claudin-14 claudin-2 claudin-5 Claudin-7 claudins ClC-2 CLDN14 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin co-culture cochlear implantation collecting duct curcumin cytokines disease dorsal root ganglion drinking rate drug development drug discovery endometrial cancer endothelia endothelial barrier enterocyte enteropathogenic E. coli (EPEC) environmental sensors epidermal barrier epithelia epithelial barrier epithelial barrier dysfunction epithelial fluid transport epithelial sodium channel (ENaC), collecting duct cells epithelial to mesenchymal transition epithelium EspF fibrosis gene transcription gland dysfunction glia limitans hearing loss HELIX syndrome Hepatitis C Virus hepatocellular carcinoma human hydrogen peroxide hydrostatic pressure hypermagnesemia hypertrophy hypokalemia immune cells in silico inflammation inflammatory bowel disease interleukin 13 intestinal mucosa intestine ion channel ion reabsorption ion transport ischemia junctional adhesion molecule kidney kidney stones Klebsiella oxytoca lipolysis-stimulated lipoprotein receptor (LSR) liver lung MAGUK proteins MDCK C7 cells MEKK3 membrane proteins metastasis mice migration molecular dynamics monocytes mouse colon mucosal immunology mucus mutations Mz-ChA-1 cells nephropathy nerve injury NES neuropathic pain neurovascular unit NFκB NHE2 NISCH syndrome NLS occludin organ preservation osmolality osmoregulation paracellular paracellular barrier paracellular channels and barriers paracellular permeability paracellular sodium transport paracellular transport paracellular water transport pathogens PDZ domain permeability phosphatidylcholine phosphorylation polarity proliferation protein domain protein interactions protein structure proximal tubule quercetin reconstructed human epidermis repair retinal pigment epithelium retinopathy Rho RhoA ROCK sensor single molecule localization microscopy skin sorting nexin 9 (SNX9) STAT3 stem cell stimulated emission depletion structured illumination microscopy super-resolution microscopy thick ascending limb tight epithelium tight junction tight junction assembly tight junctions tight junctions (TJ) tissue barrier TNF transepithelial electrical resistance (TER) transplantation tricellular tight junction tricellular tight junctions tricellulin tumor tumor suppressor UBE2Z ubiquitin vestibular function viral entry WNK4 ZO-1 ZO-2 zonula occludens |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910557404603321 |
|
Fromm Michael
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier
| The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (412 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
actomyosin
adherens junction adherens junctions aging AMP-activated protein kinase (AMPK) angubindin-1 angulin anhidrosis antibiotic-associated hemorrhagic colitis antibody antidiuretic hormone apical junctional complex apoptosis aquaporin arachnoid barrier atopic dermatitis atypical aPKCζ barrier formation barrier function biliary epithelial cells blood-biliary barrier blood-brain barrier blood-cerebrospinal fluid barrier brain barriers calcium permeability Campylobacter jejuni cancer caspase CaSR celiac disease cell growth cell polarity cell-cell contact cerebral cavernous malformation chemoresistance cholangiocellular carcinoma cholestasis chronic liver disease claudin Claudin claudin 1 claudin targeting claudin-1 claudin-12 Claudin-14 claudin-2 claudin-5 Claudin-7 claudins ClC-2 CLDN14 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin co-culture cochlear implantation collecting duct curcumin cytokines disease dorsal root ganglion drinking rate drug development drug discovery endometrial cancer endothelia endothelial barrier enterocyte enteropathogenic E. coli (EPEC) environmental sensors epidermal barrier epithelia epithelial barrier epithelial barrier dysfunction epithelial fluid transport epithelial sodium channel (ENaC), collecting duct cells epithelial to mesenchymal transition epithelium EspF fibrosis gene transcription gland dysfunction glia limitans hearing loss HELIX syndrome Hepatitis C Virus hepatocellular carcinoma human hydrogen peroxide hydrostatic pressure hypermagnesemia hypertrophy hypokalemia immune cells in silico inflammation inflammatory bowel disease interleukin 13 intestinal mucosa intestine ion channel ion reabsorption ion transport ischemia junctional adhesion molecule kidney kidney stones Klebsiella oxytoca lipolysis-stimulated lipoprotein receptor (LSR) liver lung MAGUK proteins MDCK C7 cells MEKK3 membrane proteins metastasis mice migration molecular dynamics monocytes mouse colon mucosal immunology mucus mutations Mz-ChA-1 cells nephropathy nerve injury NES neuropathic pain neurovascular unit NFκB NHE2 NISCH syndrome NLS occludin organ preservation osmolality osmoregulation paracellular paracellular barrier paracellular channels and barriers paracellular permeability paracellular sodium transport paracellular transport paracellular water transport pathogens PDZ domain permeability phosphatidylcholine phosphorylation polarity proliferation protein domain protein interactions protein structure proximal tubule quercetin reconstructed human epidermis repair retinal pigment epithelium retinopathy Rho RhoA ROCK sensor single molecule localization microscopy skin sorting nexin 9 (SNX9) STAT3 stem cell stimulated emission depletion structured illumination microscopy super-resolution microscopy thick ascending limb tight epithelium tight junction tight junction assembly tight junctions tight junctions (TJ) tissue barrier TNF transepithelial electrical resistance (TER) transplantation tricellular tight junction tricellular tight junctions tricellulin tumor tumor suppressor UBE2Z ubiquitin vestibular function viral entry WNK4 ZO-1 ZO-2 zonula occludens |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910674057303321 |
|
Fromm Michael
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Transmucosal Absorption Enhancers in the Drug Delivery Field
| Transmucosal Absorption Enhancers in the Drug Delivery Field |
| Autore | Maher Sam |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (406 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
absorption enhancement
absorption enhancer absorption enhancers absorption modifying excipients Aloe vera amino acid amphiphilic polymers and liposome antiepileptic drug antimicrobial peptide biocompatibility studies bioenhancer block copolymers brush border Caco-2 Caco-2 cells cationic functionalization cell-penetrating peptide cell-penetrating peptide (CPP) cervicovaginal tumors chitosan chitosan derivatives claudin clinical trial CNS disorders combined microsphere compound 48/80 confocal laser scanning microscopy cornea curcumin cyclodextrin cytochrome P450 drug absorption enhancer drug administration drug delivery efflux enterocyte epithelial permeability epithelial transport epithelium F-actin FITC-dextran formulation gel gemini surfactant GLP-1 hydrophobization imatinib in situ hydrogel in vivo studies insulin intestinal absorption intestinal delivery intestinal epithelial cells intestinal permeation enhancers KLAL man mast cell activator metabolism mucoadhesion mucoadhesiveness N-dodecyl-?-D-maltoside (DDM) nanocapsules nanocrystals nanomedicine nanoparticle nanoparticles nasal nasal delivery nasal formulation nasal permeability nasal vaccination nose to brain delivery nose to brain transport nose-to-brain ocular conditions ocular delivery ocular drug delivery ophthalmology oral delivery oral macromolecule delivery oral peptides osteoporosis P-glycoprotein penetration enhancer penetration enhancers permeability permeation enhancer permeation enhancers pharmacokinetic interaction pharmacokinetics PN159 polymeric micelles poorly absorbed drug preclinical PTH 1-34 pulmonary quaternization safety salcaprozate sodium sheep simulated intestinal fluid simvastatin small intestine sodium caprate sodium cholate (NaC) sugar-based surfactants teriparatide thermogel system tight junction tight junction modulator tight junctions transepithelial electrical resistance transferrin transmucosal drug delivery transmucosal permeation tryptophan vaccine adjuvant vaginal delivery whole leaf |
| ISBN | 3-03921-849-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910372785603321 |
|
Maher Sam
|
||
| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Zika Virus and Host Interactions
| Zika Virus and Host Interactions |
| Autore | Hobman Tom |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (256 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
anti-viral signaling
apoptosis arboviruses astrocytes Bcl-2 protein family blood-placental barrier C6/36 cells cell death cell entry cellular communication claudins cytokine endothelial vascular cells envelope protein extracellular vesicles fetal brain flavivirus flaviviruses fusion loop glycosylation guinea pig host host-pathogen interactions HSP90 human monocytes IFN IFNAR1 immune response infertility inflammation inflammatory mediator innate immune response innate immunity interferon JAK/STAT Leydig cells MDA5 mosquito MR766 network non-structural viral proteins NS5 NS5 protein nuclear localization pathogenesis peroxisome peroxisomes placenta protein-protein interaction RIG-I Sertoli cells sexual transmission subcutaneous T cells tight junction tight junctions vaginal viral fusion viral replication virus host interactions virus transmission virus-host interactions West Nile virus zika zika virus Zika virus ZIKA virus ZIKV ZO-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557297503321 |
|
Hobman Tom
|
||
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||