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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (528 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
ABT-737
acetazolamide acetylcholine adjuvant therapy amoeboid motility angiogenesis apoptosis arthralgia Bcl-2 family BCL2L10 biomarkers BRAF BRAF inhibitor BRAF inhibitors BRAF-mutant melanoma cancer cancer associated fibroblast cancer stem cells carbonic anhydrase cell therapy checkpoint inhibitor cholinergic system combined therapy ctDNA CXCL10 cyclopamine cytokines cytotoxicity diagnosis DOCK4 drug resistance essential oils exosomes extracellular vesicles FAK hedgehog HIPPO HuR immunity immunotherapy interferon invasion ipilimumab lactate dehydrogenase lipid metabolism liquid biopsy liver-directed-therapies machine learning MANS peptide MARCKS mechanism of action melanoma melanoma immune infiltrate melanoma markers melanoma metastasis melanoma PDX melanomagenesis metalloproteinases metastases metastasis metastatic dormancy metastatic therapy metastatic uveal melanoma (mUM) microenvironment microRNAs MITF ML258 motility mucosal melanoma muscarinic receptors n/a nanoparticles nicotinic receptors nivolumab OXPHOS patient stratification PD-1 pembrolizumab phosphorylation plasmacytoid dendritic cells prediction principal component analysis prognosis prognostication protein tyrosine phosphatase PTPs inhibitors Rac1 radiotherapy resistance rheumatoid arthritis sex-hormones sex/gender ShcD adaptor protein siRNA slow cycling phenotype small molecules SOCE STAT3 Support Vector Machine survival target therapy targeted therapy targeted-therapy therapeutic resistance therapy TLR TPC2 tumor microenvironment tumour microenvironment uveal melanoma (UM) WNT5A |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology
| Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology |
| Autore | Fioravanti Antonella |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (320 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
acute myocardial infarction
ALS Alzheimer's disease antioxidants antisense oligonucleotide apoptosis ASH autophagy beta cells breast cancer cancer chemoresistance clinical trial cross-talk diabetes endometriosis endometriosis-associated ovarian cancer epithelial-to-mesenchymal transition HBV HCC HCV high-grade serous ovarian cancer Huntington's disease hypoxia liver cancer long noncoding RNA metabolism microRNA MicroRNA MicroRNA (miRNA) microRNAs miR-27a-5p miR526b miR655 miRNA miRNAs mitochondrial dysfunction n/a NAFLD NASH neurodegeneration NF-κB nitrosative stress. exosome noncoding RNA nucleic acid medicine osteoarthritis oxidative stress pancreatic cancer Parkinson's disease physiology reactive oxygen species reactive oxygen species (ROS) redox signaling resistin ROS signal transduction siRNA superoxide (SO) synovial fibroblasts synovitis systemic lupus erythematosus therapeutic resistance therapeutic target therapeutic tolerance Thioredoxin Reductase 1 (TXNRD1) thyroid hormone translation regulation visfatin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557526003321 |
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Fioravanti Antonella
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Aspects of Cancer Stem Cell Biology : Implications for Innovative Therapies
| New Aspects of Cancer Stem Cell Biology : Implications for Innovative Therapies |
| Autore | Cavallaro Ugo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (208 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
ALDH1
ATAC-seq B4GALT1 bevacizumab bowel cancer breast cancer Cadherin 11 cancer stem cell cancer stem cells cancer therapy cell adhesion molecule chemo-resistance chemoresistance chemotherapy resistance colon colorectal CSCs dasatinib early breast cancer EC-8042 epithelial-mesenchymal transition exosomes genetic heterogeneity genome-wide HDAC inhibitors head and neck squamous cell carcinoma immunohistochemistry L1CAM lipid LUAD lung cancer metabolism neoadjuvant chemotherapy NSCLC oral cancer risk oral epithelial dysplasia oral squamous cell carcinoma organoid ovarian cancer Ovarian cancer RNA-seq saracatinib SNP array solid cancer SOX2 SRC stem cell therapeutic resistance therapy resistance TNBC transcriptome tumor progression tumoroid Wnt signaling WNT signaling β-catenin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | New Aspects of Cancer Stem Cell Biology |
| Record Nr. | UNINA-9910557112003321 |
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Cavallaro Ugo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Prognostic and Predictive Markers in Cancer Progression
| New Prognostic and Predictive Markers in Cancer Progression |
| Autore | Costantini Susan |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (294 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
acetyltransferase
AKT antigen processing machinery (APM) molecules AR biomarker biomarkers bladder cancer blood BRCA1/2 breast cancer cancer cancer immunotherapy cancer prognosis carcinogenesis cardioncology cardiotoxicity castration-resistant prostate cancer (CRPC) CD8+ T effector cells chemo-/radio resistance CSC CTCs cytokines EMT eribulin genetic syndromes genomic mutations head and neck cancer head and neck neoplasms head and neck tumors HRR HUB nodes human leukocyte antigen (HLA) hyperglycemia immune checkpoint inhibitor K-RAS oncogene laryngeal cancer lifestyle habit major histocompatibility complex (MHC) MAPK melanoma melanoma resistance to MAPK/MEK inhibitors metabolomics metastasis microRNA miRNA MSI2 mTOR musashi 2 mutations N-cadherin n/a NAA10 new metastasis nivolumab oncogene dependency oral cancer OSCC pancreatic cancer paraganglioma PDL1 pheochromocytoma PI3K PI3KCA prediction prognosis prostate cancer PTEN resistance to immune checkpoint inhibitors selenoproteins targeted therapies therapeutic resistance therapeutic target TILs TNBC transcriptomics tumor predisposition WNT |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557794803321 |
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Costantini Susan
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy
| The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy |
| Autore | Madureira Patrícia Alexandra Saraiva |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (307 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
3D co-culture
biomarker biomarkers bladder cancer breast cancer cancer cancer acidity cancer cells subpopulations cancer development cancer recurrence cancer stem cells cancer-associated fibroblast (CAF) carcinoma chemotherapy response clinical trials colon cancer cross-presentation CTLA-4 cytokine/chemokine darwinian evolution diclofenac evolutionary therapy extracellular matrix (ECM) feline mammary carcinoma glioblastoma (GB) glioma stem cells (GSC) growth factors head and neck cancer histone modification hyperosmolarity hypoxia Hypoxia Inducible Factor (HIF) immune cell infiltration immunomodulatory roles immunotherapy inhibitor KDM5B koningic acid lung cancer macrophages mammary gland metastasis microenvironment molecular docking molecular subtypes of pancreatic cancer myeloid cells myeloid derived suppressor cells myeloid-derived suppressor cells oxidative stress PAI-1 PAI-2 pancreatic stellate cells PD-1 PD-L1 plasmin plasminogen pre-metastatic niche preclinical modelling pro- and anti-tumor immune cells pro-inflammatory cytokines prognosis prostate cancer radioresistance radiosensitivity radiotherapy radiotherapy dose fractionation reactive oxygen species regulatory T cells repurposing resistance S100A10 S100A10 (p11) signaling pathways spheroid stroma syngeneic model targeted therapy therapeutic resistance TNF-α triple negative tumor growth tumor microenvironment tumor progression tumor-associated macrophages tumour microenvironment uPA uPAR |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557354203321 |
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Madureira Patrícia Alexandra Saraiva
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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