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Adipokines 2.0
| Adipokines 2.0 |
| Autore | Büchler Christa |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (406 p.) |
| Soggetto non controllato |
lipids
cathepsins neurodegeneration tocilizumab SGBS adipocytes chemerin receptors cholesterol metabolically healthy obese energy metabolism adipose-brain axis EP3 receptor leptin rheumatoid arthritis excessive gestational weight gain in vitro fat regain secreted frizzled-related protein 5 PCOS EP4 receptor leukocyte exchange protein directly activated by cAMP isoform 2 (EPAC2) extracellular remodeling insulin osteoarthritis lipid metabolism fat mass Tango bioassay fatty liver free fatty acids label-free proteomic profiling interleukin(IL)-33 sick fat polycystic ovary syndrome early-life programming inflammation gestational diabetes glucose restriction adipokines neonatal anthropometry epicardial adipose tissue (EAT) oestrous cycle Cardiovascular Diseases (CVDs) triglycerides G protein-coupled receptor 1 testicular pathologies prognosis ovary ICU biologic activity preeclempsia adipokine critical illness early pregnancy myokine liver steatosis C-C chemokine receptor-like 2 testis stimulating growth factor 2 (ST2) pig fitness human granulosa cells obesity proteolysis annexins adipose tissue biomarker ghrelin brain health sepsis adiponectin rheumatic diseases chemokine-like receptor 1 follicular fluid glucose homeostasis resistin Nonalcoholic fatty liver disease prostaglandin E2 (PGE2) visceral fat microglia weight regain complement factors alpha-fetoprotein polycystic ovary morphology chemerin cancer depression hypertension hypothalamus |
| ISBN | 3-03928-587-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404092003321 |
Büchler Christa
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (594 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
thymidylate synthase
cytotoxicity 1,2,3-triazole 1,3,4-oxadiazole 5-fluoruracil pemetrexed docking 3,4'-bis-guanidino 3-amino-4'-guanidino diphenyl ether phenyl pyridyl ether intramolecular hydrogen bond cancer cell viability HL-60 BRAF apoptosis thieno[2,3-d][1,2,3]triazine acetamide H1299 HER2 EGFR Bcl-2 inhibitors Indole-based analogues benzimidazole MTT cytotoxic assay cell cycle analysis DNA fragmentation ELISA solid/lipid nanoparticles phenstatin letrozole tubulin polymerisation inhibitor aromatase inhibitor breast cancer hybrid molecule dual-targeting molecule designed multiple ligand NaMSA cyclophosphamide histopathology testis urinary bladder anticancer agents enantioselective synthesis gastric adenocarcinoma tryptophanol concentration-guided dosing model informed dosing physiologically based pharmacokinetics sorafenib tyrosil-DNA-phosphodiesterase 1 adamantane resin acid TDP1 cytotoxic agents apoptosis induction HT-29 cells MDA-MB-231 cells mechanism prediction STAT inhibitors miR-21 hydrazide derivatives nitrogen scaffolds mitoxantrone cardiotoxicity inflammation oxidative stress age cumulative dose Trk NTRK tissue-agnostic larotrectinib entrectinib Trk fusion protein kinase inhibitors USFDA cancer patent review generic product doxazosin MD simulations combretastatin A-4 cytotoxic activity hybrid compounds indazole mucin MUC1 MUC16 immunotherapy cancer vaccine CAR (chimeric antigen receptor) ADC (antibody-drug conjugate) thiourea interleukin-6 trypan blue assay chalcones exportin-1 covalent binding CovDock anticancer activity xanthone in vitro in vivo isolation synthesis heterocyclic compound benzenesulfonamides imidazoles alkylated colony formation tumor spheroids HDAC inhibitors chalcone dual inhibitors carvedilol kidney toxicity 7-deaza-4'-thioadenosine derivatives multi-kinase inhibitor anticancer nucleoside Imiquimod drug efflux multidrug resistance Toll-Like Receptor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
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Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Male Germline Chromatin
| Male Germline Chromatin |
| Autore | Griffin Darren |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (144 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
mouse sperm chromatin
chromosome organization nuclear-3D-parameters spermiogenesis chromatin remodeling DNA double-strand breaks genetic instability mutations sperm DNA damage DNA fragmentation infertility assisted reproduction miscarriage implantation nuclear organization sperm morphometrics chromosome painting nucleoli NOR chromosome associations meiotic prophase spermatocytes Mus m. domesticus Robertsonian chromosomes chromosome translocation Y chromosome testis spermatogenesis SLY mouse oxidative stress reactive oxygen species chromatin DNA oxidation male infertility spermatozoa chromosomes chromosome territories centromeres male germ cells telomeres reproductive aging nuclear organisation epigenetic inheritance histone retention in vitro fertilisation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557561103321 |
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Griffin Darren
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Anti-inflammatory and Antioxidant Agents 2021
| Marine Anti-inflammatory and Antioxidant Agents 2021 |
| Autore | Degl'Innocenti Donatella |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (172 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
algal biome
polysaccharides bioactive entities engineered cues therapeutic attributes inflammatory bowel disease microalgae Tisochrysis lutea fucoxanthin inflammation RAW 264.7 microRNA astaxanthin dendritic cells sepsis immune dysfunction lipopolysaccharide oxidative stress Ulva lactuca polysaccharide D-galactose kidney oyster peptides spermatogenesis apoptosis hormone testis C-phycoerythrin Phormidium persicinum acute kidney injury mercury endoplasmic reticulum stress bioactive peptide cytoprotective endothelial dysfunction blue mussel acute liver injury ferroptosis oyster peptide pyroptosis zooplankton natural products antioxidant transcriptome mining |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566461803321 |
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Degl'Innocenti Donatella
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Advances on Zika Virus Research
| New Advances on Zika Virus Research |
| Autore | Martinez-Sobrido Luis |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (552 p.) |
| Soggetto non controllato |
microRNAs
antivirals reverse genetics nucleic acid computation viral pathogenesis plaque reduction neutralization test clinical trials viral genetic variation viral fitness pregnancy type I IFN antagonist prM-E proteins eye replicon antiviral responses Bacterial artificial chromosome gene expression NS1 protein viral permissiveness ZIKV–host interactions reporter virus viral persistence blood-retinal barrier virus like particles emerging arbovirus Non-human primates heme-oxygenase 1 mosquito surveillance antiviral compounds ZIKV-associated neurologic disorders external quality assessment outbreak control therapeutics cryptic promoter silencing testis neurons mutagenesis RNA-seq microsphere immunoassay host-directed antivirals molecular diagnostics Bayesian analyses astrocytomas Full-length cDNA infectious clones viral pathogenicity neural progenitor cells full-length molecular clone antiviral multiplex nucleic acid detection Asian-lineage nucleic acid strand exchange IgA African-lineage vaccines Zika research models and tools immune response IgG avidity tests polymerase chain reaction Asian lineage sexual transmission TLR7/8 neuropathogenesis cross-reactions genetic variability mosquito ZIKV infectious cDNA prostate host genetic variation monoclonal antibodies optimised anti-viral immunity QCMD arbovirus FSS13025 MR766 NS5 EQA testicular cells virus attachment flavivirus mosquito-borne flavivirus dsRNA boolean logic-processing nucleic acid probes Ziks virus viral replication Aedes aegypti infection natural history infectious RNA zika virus chimeric viruses subgenomic replicon replication human brain glial cells microglia cells hepatocytes bacterial artificial chromosome detoxification and immune system responses testes dengue viruses Zika virus insecticide resistance NS2A protein plasmid toxicity cell surface receptors serology viral evolution laboratory preparedness flaviviruses Tet-inducible dengue virus diagnosis assay standardization infectious clone ELISA innate response congenital Zika syndrome secondary infections apoptosis viral survival ocular validated rhesus macaques neuroinflammation placenta cells NHP Zika virus (ZIKV) point-of-care diagnostics isothermal nucleic acid amplification microcephaly cytopathic effects indirect immunofluorescence fetal infection therapy siRNA viral counteraction neural cells silvestrol eIF4A |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346661103321 |
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Martinez-Sobrido Luis
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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