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2015 : Which new directions for Alzheimer's disease? / / edited by Ludovic Martin
| 2015 : Which new directions for Alzheimer's disease? / / edited by Ludovic Martin |
| Autore | Ludovic Martin |
| Pubbl/distr/stampa | Frontiers Media SA, 2015 |
| Descrizione fisica | 1 online resource (122 pages) : illustrations (some colour); digital file(s) |
| Disciplina | 616.831 |
| Collana | Frontiers Research Topics |
| Soggetto topico | Alzheimer's disease - Research |
| Soggetto non controllato |
kinase inhibitors
Therapeutics tau TREM2 Alzheimers disease microbiome Aβ peptides |
| ISBN | 9782889195350 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Which new directions for Alzheimer's disease? |
| Record Nr. | UNINA-9910137538703321 |
Ludovic Martin
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| Frontiers Media SA, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Axonopathy in Neurodegenerative Disease
| Axonopathy in Neurodegenerative Disease |
| Autore | Crish Samuel D |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Collana | Frontiers Research Topics |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
axon degeneration
Neuropathy Glaucoma Mitochondrial dysfunction Chemotherapy-induced peripheral neuropathy Mitochondria tau axon transport Neuroinflammation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557530003321 |
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Crish Samuel D
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Intrinsically Disordered Proteins and Chronic Diseases
| Intrinsically Disordered Proteins and Chronic Diseases |
| Autore | Kulkarni Prakash |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (224 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
IDP
fuzzy interactions protein complementation assays split-GFP reassembly kinetics membraneless organelles optical tweezer liquid-liquid phase separation protein diffusion depletion interaction entropic force low-complexity sequences intrinsically disordered proteins PAGE4 conformational plasticity order-disorder transition phosphorylation intrinsic disordered protein extremely fuzzy complex protein interaction binding mechanism tumor protein p53 mouse double minute 2 mouse double minute 4 Kinase-inducible domain interacting domain phosphomimetics nuclear magnetic resonance transient secondary structure COR15A Late embryogenesis abundant Trifluoroethanol Nuclear magnetic resonance intrinsically disordered regions functional segments disease-related proteins protein-protein interaction subcellular location glucocorticoid receptor intrinsically disordered transactivation activity gene regulation coactivators microtubule associated protein tau intrinsically disordered protein dynamic configuration free energy landscape microtubules electrostatics diffusion protein structure prediction molecular modelling molecular dynamics tau-microtubule association conformational ensemble replica exchange molecular dynamics drug design |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557746903321 |
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Kulkarni Prakash
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Mechanism of Alzheimer's Disease
| Molecular Mechanism of Alzheimer's Disease |
| Autore | Macreadie Ian |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (228 p.) |
| Soggetto non controllato |
HOTAIR
neurosciences sleep disturbance positron emission tomography (PET) vitamin B complex neurodegeneration Tau miR-15/107 default-mode network complement receptor 1 neuronal differentiation epigenetics brain glucose metabolism oligomerization genetic risk A?O receptors prion ryanodine receptor type 3 diabetes complement cognitive behavioral therapy for insomnia cognitive function epigenome-wide association study Alzheimer’s disease calcium signaling ?-secretase tau Prolyl isomerases NEAT1 complement C3b/C4b receptor proteostasis amyloid beta yeast slow-wave sleep amyloid ? nutrition 4 protein aggregation apolipoprotein E dementia MALAT1 inositol 1 lncRNAs molecular biology methylenetetrahydrofolate reductase MTHFR gene 5-trisphosphate receptor CR1 density miR-34c aggregation heat shock protein dendritic spine S-adenosylmethionine beta amyloid ion channel inflammation sleep fragmentation cystathionine-?-lyase CTH gene DNA methylation heat shock response microglia drug target discovery amyloid-? oligomer therapy CR1 length polymorphism methylome APOE gene ubiquitin magnetic resonance imaging (MRI) neuronal degeneration type 2 diabetes Pin1 mild cognitive impairment dairy products endoplasmic reticulum oxidative stress Hispanics CDK5R1 |
| ISBN | 3-03921-408-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367750403321 |
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Macreadie Ian
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Biomarkers in Alzheimer's Disease
| Novel Biomarkers in Alzheimer's Disease |
| Autore | Villa Chiara |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (442 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
flotillin
Alzheimer's disease biomarker exosomes beta-amyloid Tau aging biomarkers cytokines cognitive decline metabolomics neuroinflammation multivariate analysis physical performance person-tailored PET/CT (18F)FDG neuropsychological assessment APP mutations APOE alleles PSEN1 PSEN2 germline mutations late onset AD early onset AD familial AD genetics of AD mitochondrial spare respiratory capacity mitochondrial membrane potential glycolytic reserve semantic memory phonemic fluency episodic memory neuropsychology neuroimaging mild cognitive impairment EEG TMS obesity diabetes inflammation Amyloid Beta mitochondrial dysfunction nutrition omega-3 fatty acids antioxidant carotenoids vitamin E cognition older adults ageing subjective cognitive decline clock genes Clock ApoE cardiovascular risk factors Alzheimer disease semantic priming amyloid beta cerebrospinal fluid amyloid beta peptide total tau phosphorylated tau diagnosis drug development clinical trials diagnostic research virus bacteria dementia blood behavioral and psychological symptoms of dementia (BPSD) Alzheimer's disease (AD) neuropsychiatry inventory scale (NPI) endophenotypes CART analysis MTHFR APOE COMT genetic variants early diagnosis biofluids amyloid cascade hypothesis glucose metabolism adipose tissue dysfunction energetic metabolism lysosomes dysfunction Type-3-Diabetes neurodegeneration amyloid tau soluble TREM2 NfL Multiplex SiMoA diagnostics messenger RNA microRNA neurotropic microbes precision medicine prognostics synaptic biomarkers neurofilament light chain |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557129403321 |
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Villa Chiara
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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P38 Signaling Pathway
| P38 Signaling Pathway |
| Autore | Cuenda Ana |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (194 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
arginine methylation
erythroid differentiation MKK3 phosphorylation, PRMT1 p38 MAPK cocaine conditioned place preference reward stress anxiety depression nucleus accumbens social interaction k opioid receptors p38α Rab5 endosome Alzheimer's Lewy Bodies amyloid-β tau α-synuclein p38-MAPK α inhibitor Alzheimer's disease synaptic plasticity neuroinflammation β-amyloid Tau Kv4.2 seizure temporal lobe epilepsy hippocampus neuronal firing and excitability p38MAPK nuclear translocation β-like importins inflammation cancer skeletal muscle energy metabolism signal transduction exercise type 2 diabetes p38 mitogen-activated protein kinase bleomycin-induced pulmonary fibrosis idiopathic pulmonary fibrosis RNA sequencing alveolar epithelial type II cells MAPK p38 physiology metabolism signaling hypoxia arrhythmia MAPK11 p38β |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557702003321 |
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Cuenda Ana
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Natural Compounds in Inflammation and Inflammatory-Related Diseases
| Role of Natural Compounds in Inflammation and Inflammatory-Related Diseases |
| Autore | Maione Francesco |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (174 p.) |
| Soggetto non controllato |
toxicity
long-lasting effect iso-?-acids ammonium glycyrrhizinate metabolomics cytokines Alnus sibirica energy metabolism curcumin antineuroinflammation nitric oxide antioxidant nutraceutical food liver nardochinoid B endometriosis adipose tissue Nardostachys chinensis tau macrophage nociception heme oxygenase-1 enzymatic hydrolysis IL-6 nuciferine docking chronic nonbacterial prostatitis black tea polyphenol network pharmacology Tagetes patula L. SEM lipopolysaccharide solid lipid nanoparticle tauopathy memory lupane-type triterpene acute lung injury inducible nitric oxide synthase inflammation anti-inflammatory microglia resveratrol theaflavins hirsutanonol short-term high-fat diet inflammatory disease juçara oregonin PPARs NF-?B neuroprotection Portulaca oleracea TNF-? depression |
| ISBN | 3-03921-553-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756703321 |
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Maione Francesco
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Shaping the Brain by Neuronal Cytoskeleton: From Development to Disease and Regeneration
| Shaping the Brain by Neuronal Cytoskeleton: From Development to Disease and Regeneration |
| Autore | Laura Sayas C |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (185 p.) |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
neuronal cytoskeleton
astrocyte cytoskeleton microtubules (MTs) actin cytoskeleton tau neuron |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Shaping the Brain by Neuronal Cytoskeleton |
| Record Nr. | UNINA-9910557662003321 |
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Laura Sayas C
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sphingolipids : From Pathology to Therapeutic Perspectives - A Themed Honorary Issue to Prof. Lina Obeid
| Sphingolipids : From Pathology to Therapeutic Perspectives - A Themed Honorary Issue to Prof. Lina Obeid |
| Autore | van Echten-Deckert Gerhild |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (292 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
S1P receptor
inflammation S1P transporter spinster homolog 2 barrier dysfunction anxiety depression sphingolipids sphingomyelinase ceramidase Smpd1 acid sphingomyelinase forebrain depressive-like behavior anxiety-like behavior ceramide ceramides ceramidases neurodegenerative diseases infectious diseases sphingosine 1-phoshate sphingosine 1-phosphate receptor S1P1-5 sphingosine 1-phosphate metabolism sphingosine 1-phosphate antagonistst/inhibitors sphingosine 1-phosphate signaling stroke multiple sclerosis neurodegeneration fingolimod Sphingosine-1-phosphate obesity type 2 diabetes insulin resistance pancreatic β cell fate hypothalamus sphingosine-1-phosphate ischemia/reperfusion cardioprotection vasoconstriction coronary flow myocardial function myocardial infarct albumin type 1 diabetes beta-cells islets insulin cytokines S1P animal models cystic fibrosis autophagy myriocin Aspergillus fumigatus CLN3 disease Cln3Δex7/8 mice flupirtine allyl carbamate derivative apoptosis cancer gangliosides immunotherapy metastasis phenotype switching sphingosine 1-phosphate Sphingosine 1-phosphate (S1P) S1P-lyase (SGPL1) tau calcium histone acetylation hippocampus cortex astrocytes neurons sphingosine kinase G-protein-coupled receptors Gαq/11 sphingosine kinase 1 SK1 microRNA transcription factor hypoxia long non-coding RNA |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Sphingolipids |
| Record Nr. | UNINA-9910557545203321 |
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van Echten-Deckert Gerhild
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Untangling the Role of Tau in Physiology and Pathology
| Untangling the Role of Tau in Physiology and Pathology |
| Autore | Avila Jesus |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (254 p.) |
| Soggetto topico |
Science: general issues
Neurosciences |
| Soggetto non controllato |
Alzheimer
dementia microtubules neurodegeneration tau tauopathies |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557581203321 |
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Avila Jesus
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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