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Integrative Multi-Omics in Biomedical Research
| Integrative Multi-Omics in Biomedical Research |
| Autore | Gerner Christopher |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (178 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
acute myeloid leukemia
analysis flow anti-angiogenesis ATRA Barrett's esophagus batch variations bioinformatics cardiac metaplasia cGAS cheminformatics curcumin DNA sensing eicosanoids endometriosis esophageal adenocarcinoma exercise fetal calf serum heart HL-60 cell line host-pathogen interactions IFI16 induced differentiation inflammation innate immunity key molecules label-free method for drugs lipid lipidomics machine learning macrophages mass spectrometry mechanism of action metabolomics microbiota multi-omics multi-omics analysis myocardial infarction (MI) n/a natural products peroxisomes planned myocardial infarction (PMI) post-translational modifications protein interactions proteome proteomics receptor tyrosine kinases regulatory pathway modelling secretome SRM study design target identification target validation transcription factors transcriptome transcriptomics virus-host interactions |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557769003321 |
Gerner Christopher
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Protein-Ligand Interactions: Target Identification and Drug Discovery
| Protein-Ligand Interactions: Target Identification and Drug Discovery |
| Autore | Altieri Fabio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (184 p.) |
| Soggetto topico |
Chemistry
Research and information: general |
| Soggetto non controllato |
ACE
acetylcholinesterase amyloid beta aggregation brassicasterol cancer cell death cell viability CoCl2 drug development drug discovery endocrine disruptor compound fatty acid conjugation FcRn-mediated recycling fluorescence spectroscopy GADD45β heat shock protein 70 Hsp70 HSV HSV-1 DNA polymerase HSV-1 TK human CDK2 human umbilical artery kinase regulation lipid signalling lipid-protein interaction lung cancer cell line membrane mitochondrial membrane potential MKK7 molecular biophysics molecular docking molecular docking simulation molecular dynamics multi-target drug multiple myeloma Mycobacterium tuberculosis NCI60 COMPARE analysis neuroprotection PGRMC1 phosphatidylinositols phytosterols piperine protein-ligand interaction reactive oxygen species (ROS) serum albumin serum half-life extension sigma ligands sigma receptors SIGMAR1 small-molecule derivatives of salicylanilide STD-NMR structure-activity relationship target identification thyroid diseases TMEM97 translocator protein (TSPO) UDP-galactopyranose mutase vascular homeostasis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Protein—Ligand Interactions
Protein-Ligand Interactions Protein–Ligand Interactions |
| Record Nr. | UNINA-9910557497703321 |
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Altieri Fabio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday: Natural Products in Modern Drug Discovery
| Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday: Natural Products in Modern Drug Discovery |
| Autore | Hussain Hidayat |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (360 p.) |
| Soggetto topico |
Chemistry
Organic chemistry Research and information: general |
| Soggetto non controllato |
ampullosporin
angiogenesis anti-tumor peptides antibody engineering anticancer anticancer activity antifungal antiproliferative apoptosis apoptosis resistance ATG 4B biorthogonal chemistry bispecific antibody botanical agents breast cancer butein cancer stem cells cancer treatment caspase-3 click chemistry co-culture coronavirus Cosmospora sp COX inhibitory cytotoxic cytotoxic activity DARTS Decachaeta incompta demissidine docking drug resistance ECD-TDDFT electron paramagnetic resonance (EPR) spectroscopy flavonoids frondoside-A fusidic acid glutamic acid methyl ester hepatocellular carcinoma in vitro model incomptine A invasion iTRAQ kaempferol lung cancer Magnaporthe oryzae marine fungi medicinal herbs melanoma MERS-CoV metabolomics metastasis molecular docking molecular networking multi-component reaction n/a natural products ophiobolin A PCD peptaibols phytochemicals phytopathogen polygodial pregnancy proliferation RCE-4 ROS production SARS-CoV SARS-CoV-2 Sepedonium ampullosporum sesquiterpene lactone solanidane alkaloids solanidine solid-phase peptide synthesis soudanone Sparticola junci Src STAT3 stemness steroidal alkaloids structure elucidation target identification TEMPO-conjugate the Bcl-2-Beclin 1 complex Trypsiligase tumor growth tumor heterogeneity tumor microenvironment (TME) viability violacein Wittig reaction |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday |
| Record Nr. | UNINA-9910585945403321 |
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Hussain Hidayat
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tuberculosis Drug Discovery and Development 2019
| Tuberculosis Drug Discovery and Development 2019 |
| Autore | Riccardi Giovanna |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (296 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
anti-TB drug pipeline
anti-virulence compounds antibiotic antimicrobial drug resistance (AMR) antimycobacterial antituberculosis agents artificial pneumothorax BCG bedaquiline biomarkers Carlo Forlanini caseum cell envelope clinical studies clinical trial CTVD delpazolid discovery DNA gyrase dormancy DprE1 inhibitor drug combination drug development drug discovery drug resistance drug-drug interactions EDCTP electron transport chain energy metabolism genomics granulomas host-directed therapy IAVI in vitro in vivo isoniazid lead generation lipidomics macozinone mechanism of action mechanisms of resistance metabolomics MID3 mode of action multi-drug resistance mutations mycobacteria mycobacterium Mycobacterium tuberculosis n/a oxidative phosphorylation pharmacodynamics pharmacokinetics phenotypic screening PknB PknG post-treatment sequelae privileged targets promiscuous targets proteomics pulmonary rehabilitation Q203 rifampin structure-based drug design surgery target target identification target-based drug design target-based screening TB TBVI toxicity transcriptomics tuberculosis tuberculosis treatment tuberculosis vaccines |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557627203321 |
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Riccardi Giovanna
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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