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Actinomycetes : The Antibiotics Producers
| Actinomycetes : The Antibiotics Producers |
| Autore | Stegmann Evi |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (362 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Streptomyces
biogeography comparative genomics diversification secondary metabolite biosynthetic gene clusters SMGC natural products streptomyces rishirilide biosynthesis polyketides polynucleotide phosphorylase ribonuclease regulation promoter RNA decay polyadenylation (p)ppGpp antibiotic antibiotics geomicrobiology Illumina sequencing microbiome diversity Actinobacteria Cave microbiology secondary metabolite rare Actinobacteria Amycolatopsis unculturability siderophore glycopeptide antibiotics dbv cluster regulatory genes StrR LAL LuxR solo dalbavancin A40926 Streptomyces lividans secretion pathways secretory proteins signal peptides actinomycetes teicoplanin van resistance genes Streptomyces tsukubaensis tacrolimus FK506 omics screening secondary metabolism differentiation elicitors morphology liquid cultures metagenomics rare actinomycetes dereplication metabolomics genome mining secondary metabolites novel compounds physicochemical screening physical and chemical properties structural diversity biological activity Actinoallomurus antibiotics polyethers lysolipin minimal PKS II cyclases benz[a]naphthacene quinone tridecaketide aromatic polyketide pentacyclic angular polyphenol extended polyketide chain actinobacteria β-lactamase resistance β-lactamase inhibitor polyketide synthases acyltransferases engineering new bioactive compounds symbiosis drug discovery chemical ecology culture-based approaches strain specialized metabolites biosynthetic gene cluster |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Actinomycetes |
| Record Nr. | UNINA-9910557114803321 |
Stegmann Evi
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Clinical Studies, Big Data, and Artificial Intelligence in Nephrology and Transplantation
| Clinical Studies, Big Data, and Artificial Intelligence in Nephrology and Transplantation |
| Autore | Cheungpasitporn Wisit |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (374 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tacrolimus
C/D ratio tacrolimus metabolism everolimus conversion kidney transplantation gut microbiome renal transplant recipient diarrhea immunosuppressive medication gut microbiota 16S rRNA sequencing butyrate-producing bacteria Proteobacteria torquetenovirus immunosuppression transplantation immunosuppressed host outcome renal transplantation Goodpasture syndrome anti-GBM disease epidemiology hospitalization outcomes acute kidney injury risk prediction artificial intelligence patent ductus arteriosus conservative management blood pressure eradication interferon-free regimen hepatitis C infection kidney transplant allograft steatosis lipopeliosis transplant numbers live donors public awareness Google TrendsTM machine learning big data nephrology chronic kidney disease NLR PLR RPGN predictive value hemodialysis withdrawal cellular crescent global sclerosis procurement kidney biopsy glomerulosclerosis minimally-invasive donor nephrectomy robot-assisted surgery laparoscopic surgery organ donation living kidney donation MeltDose® LCPT renal function liver transplantation metabolism erythropoietin fibroblast growth factor 23 death weekend effect in-hospital mortality comorbidity dialysis elderly klotho α-Klotho FGF-23 kidney donor Nephrology CKD-MBD CKD-Mineral and Bone Disorder deceased donor Eurotransplant Senior Program risk stratification intensive care kidney transplant recipients long-term outcomes graft failure cardiovascular mortality lifestyle inflammation vascular calcification bone mineral density dual-energy X-ray absorptiometry living donation repeated kidney transplantation graft survival prolonged ischaemic time patient survival pre-emptive transplantation metabolomics urine acute rejection allograft cystatin C hyperfiltration kidney injury molecule (KIM)-1 tubular damage genetic polymorphisms (cardiac) surgery inflammatory cytokines clinical studies chronic kidney disease (CKD) no known kidney disease (NKD) ICD-10 billing codes phenotyping electronic health record (EHR) estimated glomerular filtration rate (eGFR) machine learning (ML) generalized linear model network (GLMnet) random forest (RF) artificial neural network (ANN), clinical natural language processing (clinical NLP) discharge summaries laboratory values area under the receiver operating characteristic (AUROC) area under the precision-recall curve (AUCPR) fibrosis extracellular matrix collagen type VI living-donor kidney transplantation ethnic disparity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557367503321 |
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Cheungpasitporn Wisit
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Hereditary Hemorrhagic Telangiectasia : Recent Advances and Future Challenges
| Hereditary Hemorrhagic Telangiectasia : Recent Advances and Future Challenges |
| Autore | Mager Hans-Jurgen |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (228 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
hereditary hemorrhagic telangiectasia
rare diseases telangiectasis transforming growth factor-beta (TGF-β) Smad pathway gastrointestinal bleeding epistaxis nosebleeds tacrolimus nasal ointment genetic disease rare disease hereditary hemorrhagic telangiectasia (HHT) telangiectases mechanical damage sun-induced trauma vascular malformations Endoglin activin-receptor-like kinase 1 Hereditary Hemorrhagic Telangiectasia antithrombotic therapy anticoagulants antiplatelets bleeding safety HHT ALK1 endoglin raloxifene bazedoxifene tranexamic acid propranolol FK506 etamsylate N-acetylcysteine pulmonary arteriovenous malformations transcatheter embolotherapy screening guidelines Hereditary hemorrhagic telangiectasia pediatrics genotype–phenotype correlation arteriovenous malformation ENG ACVRL1 SMAD4 microRNA biomarker plasma arteriovenous malformations (AVMs) angiogenesis activin receptor-like kinase 1 (ALK1) transforming growth factor beta (TGF-β) bone morphogenetic protein (BMP) propranolol gel epistaxis severity score nasal endoscopy antiangiogenic properties non-coding RNAs microRNAs long non-coding RNAs biomarkers endothelial cells hereditary hemorrhagic telangiectasia (HHT), second-hit arteriovenous malformation (AVM) Smad4 inflammation shear stress vascular injury somatic mutation cell adhesion vascular endothelial growth factor (VEGF) telangiectasia hereditary hemorrhagic survival life expectancy pulmonary arteriovenous malformation contrast enhanced magnetic resonance angiography liver MRI ultrasound AVM bevacizumab Osler–Weber–Rendu hereditary hemorrhagic telangiectasia/HHT/osler’s disease cerebral ischemic lesions catheter based embolization therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Hereditary Hemorrhagic Telangiectasia |
| Record Nr. | UNINA-9910557578003321 |
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Mager Hans-Jurgen
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Precision Medicine : Applied Concepts of Pharmacogenomics in Patients with Various Diseases and Polypharmacy
| Precision Medicine : Applied Concepts of Pharmacogenomics in Patients with Various Diseases and Polypharmacy |
| Autore | Turgeon Jacques |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (170 p.) |
| Soggetto topico |
Medicine
Clinical & internal medicine |
| Soggetto non controllato |
fibromyalgia (FM)
myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) microRNA miRNome pharmacogenomics pharmacoepigenomics SM2miR Pharmaco-miR repoDB ME/CFS Common Data Elements (CDEs) dihydropyrimidine dehydrogenase DPYD 5-fluorouracil fluoropyrimidine therapeutic drug monitoring orthotopic liver transplant busulfan glutathione S-transferase genetic polymorphism limited sampling strategy pharmacokinetics clinical pharmacogenetics pharmacogenetic testing adverse drug reactions genotype phenotype pharmacogene barriers to pharmacogenetics implementation Sub-Saharan Africa chronic low back pain (cLBP) genetics personalized treatment polymorphism CYP450 tacrolimus CYP3A5 liver transplant pharmacogenomic minority data collection drug biomarker pharmacogenetics pharmacogenetic test personalized medicine gene expression infliximab adalimumab ulcerative colitis Crohn disease inflammatory bowel disease |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Precision Medicine |
| Record Nr. | UNINA-9910585940803321 |
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Turgeon Jacques
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Progress and Recent Advances in Solid Organ Transplantation
| Progress and Recent Advances in Solid Organ Transplantation |
| Autore | Thongprayoon Charat |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
living donation
nephrectomy hand-assisted laparoscopic nephrectomy body composition complications simultaneous pancreas-kidney transplantation immunosuppression graft order sequence outcome survival kidney transplantation hydrogen diarrhea small intestinal bacterial overgrowth sickle cell disease sickle cell transplantation outcomes big data tacrolimus metabolism C/D ratio cholesterol dyslipidemia LDL-C liver transplantation hematuria chronic kidney disease tocilizumab clazakizumab desensitization anti-HLA alloantibody post traumatic growth psychiatric morbidity network analysis ESAS MINI CPC DCPR distress demoralization alexithymia anxiety antibody-mediated rejection recurrent primary disease renal transplantation pancreas transplantation cold ischemia time delayed graft function Eurotransplant Senior Program end-stage renal disease intensive care unit bioimpedance analysis drug dosing lean body mass index pharmacokinetics tacrolimus C/D ratio mineral bone disorder parathyroidectomy parathyroid hormone osteoporosis bone fractures Contrast-enhanced ultrasound kidney perfusion kidney function kidney donation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576885203321 |
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Thongprayoon Charat
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances and Clinical Outcomes of Kidney Transplantation : Volume 2
| Recent Advances and Clinical Outcomes of Kidney Transplantation : Volume 2 |
| Autore | Cheungpasitporn Wisit |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (270 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
malondialdehyde
oxidative stress new-onset diabetes renal transplantation BK virus BK virus nephropathy kidney allograft transplantation Alport syndrome children autosomal dominant polycystic kidney disease epidemiology hospitalization kidney transplantation subarachnoid hemorrhage malignancy post-transplant malignancy renal cell carcinoma meta-analysis systematic reviews tacrolimus C/D-ratio pharmacokinetics opportunistic infection allograft survival urological complications ureteric stent urinary tract infection timing of removal living donor ethnicity age obesity genetic relationship donor/recipient atypical hemolytic uremic syndrome eculizumab glucose intolerance insulin secretion insulin resistance oral glucose tolerance test healthy subject hyperchloremia kidney graft dysfunction living donor kidney transplantation Uropathogenic E. coli UPEC phylogeny genomics antibiotic resistance virulence traits night-time renal transplantation graft survival patient survival/outcome surgical complications acute rejection lymphocyte CD45RC Belatacept cardiovascular high risk outcome machine perfusion organ preservation temperature hypothermic normothermic transplant proton-pump inhibitors iron iron deficiency polyomavirus BKV kidney glomerulus BKVAN nephropathy fluid management delayed graft function goal-directed fluid therapy calcineurin inhibitor nephrotoxcity C/D ratio tacrolimus metabolism ADPKD native nephrectomy patient outcome perioperative complications epidermal growth factor creatinine graft failure new onset diabetes after renal transplantation single nucleotide polymorphisms urinary biomarkers α-GST π-GST nephrotoxicity urinary excretion of N1-methylnicotinamide mortality niacin status dietary intake tryptophan vitamin B3 Kidney transplant vitamin C cancer mortality mycophenolic acid immunosuppression plasmapheresis oxalate hyperoxaluria kidney transplant recipients post-transplantation diabetes mellitus all-cause mortality cardiovascular mortality infectious mortality magnesium hypomagnesaemia cancer kidney transplant survival living kidney donation living-donor kidney transplantation beliefs inequity ischemia reperfusion injury innate immune system adaptive immune system apoptosis necrosis hypoxic inducible factor endothelial dysfunction proton pump inhibitor transplant rejection GFR insulin-like growth factor 1 growth hormone muscle mass patient survival physical activity renal transplant recipients kidney transplant (KT) donor-specific antibodies (DSA) C3d-binding assay antibody-mediated rejection (AMR) arsenic diet fish consumption post-transplant diabetes mellitus N1-methyl-2-pyridone-5-carboxamide N1-methylnicotinamide urinary excretion kidney function biomarker branched chain amino acids posttransplant diarrhea methanogenesis Methanosphaera stadtmanae mucins sulfate-reducing bacteria acute humoral rejection first-line therapy outcomes proteasome inhibitor renal transplant transplant recipients calcineurin inhibitors FK506 pharmacokinetic fast tacrolimus metabolizers |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Recent Advances and Clinical Outcomes of Kidney Transplantation |
| Record Nr. | UNINA-9910557787303321 |
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Cheungpasitporn Wisit
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances and Clinical Outcomes of Kidney Transplantation
| Recent Advances and Clinical Outcomes of Kidney Transplantation |
| Autore | Cheungpasitporn Wisit |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (342 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
malondialdehyde
oxidative stress new-onset diabetes renal transplantation BK virus BK virus nephropathy kidney allograft transplantation Alport syndrome children autosomal dominant polycystic kidney disease epidemiology hospitalization kidney transplantation subarachnoid hemorrhage malignancy post-transplant malignancy renal cell carcinoma meta-analysis systematic reviews tacrolimus C/D-ratio pharmacokinetics opportunistic infection allograft survival urological complications ureteric stent urinary tract infection timing of removal living donor ethnicity age obesity genetic relationship donor/recipient atypical hemolytic uremic syndrome eculizumab glucose intolerance insulin secretion insulin resistance oral glucose tolerance test healthy subject hyperchloremia kidney graft dysfunction living donor kidney transplantation Uropathogenic E. coli UPEC phylogeny genomics antibiotic resistance virulence traits night-time renal transplantation graft survival patient survival/outcome surgical complications acute rejection lymphocyte CD45RC Belatacept cardiovascular high risk outcome machine perfusion organ preservation temperature hypothermic normothermic transplant proton-pump inhibitors iron iron deficiency polyomavirus BKV kidney glomerulus BKVAN nephropathy fluid management delayed graft function goal-directed fluid therapy calcineurin inhibitor nephrotoxcity C/D ratio tacrolimus metabolism ADPKD native nephrectomy patient outcome perioperative complications epidermal growth factor creatinine graft failure new onset diabetes after renal transplantation single nucleotide polymorphisms urinary biomarkers α-GST π-GST nephrotoxicity urinary excretion of N1-methylnicotinamide mortality niacin status dietary intake tryptophan vitamin B3 Kidney transplant vitamin C cancer mortality mycophenolic acid immunosuppression plasmapheresis oxalate hyperoxaluria kidney transplant recipients post-transplantation diabetes mellitus all-cause mortality cardiovascular mortality infectious mortality magnesium hypomagnesaemia cancer kidney transplant survival living kidney donation living-donor kidney transplantation beliefs inequity ischemia reperfusion injury innate immune system adaptive immune system apoptosis necrosis hypoxic inducible factor endothelial dysfunction proton pump inhibitor transplant rejection GFR insulin-like growth factor 1 growth hormone muscle mass patient survival physical activity renal transplant recipients kidney transplant (KT) donor-specific antibodies (DSA) C3d-binding assay antibody-mediated rejection (AMR) arsenic diet fish consumption post-transplant diabetes mellitus N1-methyl-2-pyridone-5-carboxamide N1-methylnicotinamide urinary excretion kidney function biomarker branched chain amino acids posttransplant diarrhea methanogenesis Methanosphaera stadtmanae mucins sulfate-reducing bacteria acute humoral rejection first-line therapy outcomes proteasome inhibitor renal transplant transplant recipients calcineurin inhibitors FK506 pharmacokinetic fast tacrolimus metabolizers |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557632603321 |
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Cheungpasitporn Wisit
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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