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Drug Metabolism/Transport and Pharmacokinetics
| Drug Metabolism/Transport and Pharmacokinetics |
| Autore | Song Im-Sook |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (232 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
tofacitinib
dose-dependent pharmacokinetics hepatic and intestinal first-pass effect rats catalposide in vitro human metabolism UDP-glucuronosyltransferase sulfotransferase carboxylesterase celecoxib drug–drug interaction fluorescence HPLC metabolism repaglinide HSG4112 anti-obesity agent stereoselectivity pharmacokinetics compound K protopanaxadiol (PPD) biliary excretion intestinal metabolism Carthamus tinctorius extract notoginseng total saponins comparative pharmacokinetic study large volume direct injection compatibility mechanism mertansine human hepatocytes cytochrome P450 UDP-glucuronosyltransferases sodium-glucose cotransporter 2 (SGLT2) inhibitors DWP16001 kidney distribution inhibition mode diabetes transporter-enzyme interplay influx transporter efflux transporter physiologically based pharmacokinetic model cytochrome P450 enzymes tiropramide healthy Korean subjects modeling population pharmacokinetic quercetin breast cancer resistance protein inhibitor prazosin sulfasalazine kinetic analysis food–drug interactions Caco-2 EpiIntestinal first-pass P-gp BCRP drug transporter CYP3A4 oral availability automatization drug absorption drug dosing head-and-neck cancer real-time measurements taxanes tissue engineering UHPLC-MS/MS metformin verapamil drug interaction organic cation transporter 2 renal excretion acute renal failure gentamicin cisplatin hepatic CYP3A1(23) creatinine clearance renal clearance nonrenal clearance |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607703321 |
Song Im-Sook
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Heparan Sulfate Proteoglycans and Their Endogenous Modifying Enzymes: Cancer Players, Biomarkers and Therapeutic Targets
| Heparan Sulfate Proteoglycans and Their Endogenous Modifying Enzymes: Cancer Players, Biomarkers and Therapeutic Targets |
| Autore | Cassinelli Giuliana |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (131 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
heparan sulfate proteoglycan
heparanase sulfotransferase glypican cancer therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Heparan Sulfate Proteoglycans and Their Endogenous Modifying Enzymes |
| Record Nr. | UNINA-9910557255503321 |
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Cassinelli Giuliana
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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