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Drug Metabolism/Transport and Pharmacokinetics
| Drug Metabolism/Transport and Pharmacokinetics |
| Autore | Song Im-Sook |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (232 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
tofacitinib
dose-dependent pharmacokinetics hepatic and intestinal first-pass effect rats catalposide in vitro human metabolism UDP-glucuronosyltransferase sulfotransferase carboxylesterase celecoxib drug–drug interaction fluorescence HPLC metabolism repaglinide HSG4112 anti-obesity agent stereoselectivity pharmacokinetics compound K protopanaxadiol (PPD) biliary excretion intestinal metabolism Carthamus tinctorius extract notoginseng total saponins comparative pharmacokinetic study large volume direct injection compatibility mechanism mertansine human hepatocytes cytochrome P450 UDP-glucuronosyltransferases sodium-glucose cotransporter 2 (SGLT2) inhibitors DWP16001 kidney distribution inhibition mode diabetes transporter-enzyme interplay influx transporter efflux transporter physiologically based pharmacokinetic model cytochrome P450 enzymes tiropramide healthy Korean subjects modeling population pharmacokinetic quercetin breast cancer resistance protein inhibitor prazosin sulfasalazine kinetic analysis food–drug interactions Caco-2 EpiIntestinal first-pass P-gp BCRP drug transporter CYP3A4 oral availability automatization drug absorption drug dosing head-and-neck cancer real-time measurements taxanes tissue engineering UHPLC-MS/MS metformin verapamil drug interaction organic cation transporter 2 renal excretion acute renal failure gentamicin cisplatin hepatic CYP3A1(23) creatinine clearance renal clearance nonrenal clearance |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607703321 |
Song Im-Sook
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Memorial Issue Dedicated to Dr. Howard D. Flack: The Man behind the Flack Parameter
| Memorial Issue Dedicated to Dr. Howard D. Flack: The Man behind the Flack Parameter |
| Autore | Fromm Katharina M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (222 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
pyrazine-benzimidazole
spin crossover iron(II) ligand field nephelauxetic arylsulfonates pyridinium salt formation single-phase solvent system sulfonate synthesis sulfonyl chlorides X-ray crystallography crystallography Howard Flack 2-bromo-3-methylbutyric acid 2-bromo-3-methylbutanoic acid 2-bromoisovaleric acid halogenated carboxylic acid hydrogen bonding chirality absolute configuration racemate crystal structure Flack parameter coordination chemistry MOFs twinning structure analysis hydroborate anions packing lanthanide trichloride complexes diphosphine dioxide coordination complexes X-ray structures stereoselectivity hydrogen-bonding complex ion disiloxanes intermolecular interactions Hirshfeld surface analysis molecular models silicon γ-(+)-decalactone in situ cryo-crystallization flavoring agent lactone vibrational circular dichroism solid-gas reaction chemisorption nitrosyl Flack test Erdmann's anion bath salts street drugs cocaine methamphetamine methylone π-π interactions racemic mimics kryptoracemic crystallization hydrogen-bond propensity hydrogen-bond coordination supramolecular synthon hydrogen-bond energies Cambridge Structural Database molecular electrostatic potential pyrazoles Rifamycin O ansamysin antibacterial semi-synthesis Alder-Ene conformation zwitterionic |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Memorial Issue Dedicated to Dr. Howard D. Flack |
| Record Nr. | UNINA-9910557365103321 |
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Fromm Katharina M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Trends in Asymmetric Catalysis
| New Trends in Asymmetric Catalysis |
| Autore | Della Sala Giorgio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (172 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
N-heterocyclic carbenes (NHC)
Lewis acid cooperative catalysis asymmetric synthesis umpolung amines imines photoredox catalysis radical additions radical-radical couplings stereoselectivity umpolung chemistry visible light proline organocatalysis asymmetric aldol reaction methanol/water mixtures sustainability asymmetric catalysis salen complexes ring-opening epoxide kinetic resolution organic electrosynthesis electrochemistry enantioselectivity transition-metal catalysis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557355803321 |
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Della Sala Giorgio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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