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MicroRNA and Cancer
| MicroRNA and Cancer |
| Autore | Tucci Paola |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (298 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Breast cancer
Hypoxia inducible factor 1-alpha (HIF-1α) MicroRNA (miRNA) miR526b miR655 Oxidative stress Migration Cyclooxygenase-2 (COX-2) Prostaglandin E2 receptor 4 (EP4) PI3K/Akt adipokines endometrial cancer estrogens hyperinsulinemia insulin insulin resistance insulin signaling insulin-like growth factors microRNA miRNA ovarian cancer survival prognostic factor serum LDH blood biomarker circulating microRNA plasma immunotherapy immune checkpoint inhibitors metastatic melanoma hepatocellular carcinoma metastasis exosome bioinformatics analysis renal cancer RCC ccRCC meta-analysis miRNAs normal B-cell development B-CLL miRNA-transcription factor network regulation biomarker therapy prognosis diagnosis progression prediction smoking non-small cell lung cancer methylation miR-584-5p YKT6 snoRNA 2'-O-methylation pseudouridylation malignant melanoma cancer stem cell stemness head and neck squamous cell carcinoma colon cancer cancer stem cells microRNAs deformability PARP replication stress targeted therapy breast cancer circulating biomarkers medulloblastoma brain tumour subgroups stem cells |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213503321 |
Tucci Paola
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting STAT3 and STAT5 in Cancer
| Targeting STAT3 and STAT5 in Cancer |
| Autore | Moriggl Richard |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (578 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
multiple myeloma
STAT3 S3I-1757 nanoparticle CD38 siRNA/RNAi polyethylenimine PEI lipopolyplex siRNA delivery glioma glioblastoma STAT5 AKT ERK1/2 prolactin androgens prostate cancer knockout escape mechanisms stem/progenitor cells cell hierarchy cancer CD4+ T cells CD8+ T cells myeloid cells immune check point hepatitis C virus (HCV) cirrhosis hepatocellular carcinoma (HCC) endoplasmic reticulum (ER) stress oxidative stress (OS) unfolded protein response (UPR) microRNA-122 (miR-122) nuclear factor erythroid 2-related factor 2 (NRF2) signal transducer and activator of transcription 3 (STAT3) hepatocyte nuclear factor 4 alpha (HNF4A) solid cancers cell cycle apoptosis inflammation mitochondria stemness tumor suppression melanoma autoimmune disease immunotherapy tumor-immune cell interactions breast cancer PD-L1 M2 macrophages NK cells STAT3 inhibitor XIII hedging transaction costs dynamic programming risk management post-decision state variable cancer progression cancer-stem cell cytokine therapy resistance metastasis immunosuppression tumor microenvironment proliferation tyrosine kinase 2 JAK family of protein tyrosine kinases signal transducer and activator of transcription cytokine receptor signaling gain-of-function mutation tumorigenesis ADAM17 interleukin-6 trans-signaling epidermal growth factor receptor (EGF-R) shedding metalloprotease tumor necrosis factor alpha (TNFα) inflammation associated cancer colon cancer lung cancer SH2 domain mutations autosomal-dominant hyper IgE syndrome inflammatory hepatocellular adenomas T-cell large granular lymphocytic leukemia T-cell prolymphocytic leukemia growth hormone insensitivity syndrome nuclear pore complex nuclear transport receptors nucleocytoplasmic shuttling targeting tumor-associated macrophages adoptive T cell therapy immune suppression STAT transcription factors JAK STAT T-PLL T-cell leukemia meta-analysis STAT5B signaling small-molecule inhibitors cancer models companion animals comparative oncology pharmacological inhibitor STAT5 signaling chemotherapy resistance myeloid leukemia heat shock proteins chaperones stabilization targeted therapy ovarian cancer hematopoietic cancers therapeutic targeting pharmacological inhibitors mTOR Bone Marrow Failure Syndromes lymphocytes lymphoma T-cells RHOA NGS MPN JAK2 V617F neoplastic stem cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557623503321 |
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Moriggl Richard
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday: Natural Products in Modern Drug Discovery
| Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday: Natural Products in Modern Drug Discovery |
| Autore | Hussain Hidayat |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (360 p.) |
| Soggetto topico |
Research & information: general
Chemistry Organic chemistry |
| Soggetto non controllato |
multi-component reaction
fusidic acid TEMPO-conjugate electron paramagnetic resonance (EPR) spectroscopy caspase-3 incomptine A sesquiterpene lactone Decachaeta incompta cytotoxic activity iTRAQ apoptosis ROS production violacein hepatocellular carcinoma proliferation stemness natural products tumor microenvironment (TME) lung cancer phytochemicals botanical agents steroidal alkaloids solanidane alkaloids demissidine solanidine flavonoids coronavirus SARS-CoV-2 SARS-CoV MERS-CoV anticancer activity apoptosis resistance ophiobolin A polygodial Wittig reaction melanoma tumor heterogeneity pregnancy anti-tumor peptides in vitro model medicinal herbs cancer treatment cancer stem cells drug resistance metastasis RCE-4 PCD ATG 4B the Bcl-2-Beclin 1 complex Sparticola junci structure elucidation ECD-TDDFT COX inhibitory molecular docking antiproliferative cytotoxic Sepedonium ampullosporum peptaibols ampullosporin glutamic acid methyl ester solid-phase peptide synthesis antifungal anticancer target identification kaempferol docking DARTS Src breast cancer butein frondoside-A STAT3 angiogenesis invasion viability tumor growth marine fungi Cosmospora sp soudanone Magnaporthe oryzae co-culture phytopathogen molecular networking metabolomics bispecific antibody Trypsiligase click chemistry biorthogonal chemistry antibody engineering |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday |
| Record Nr. | UNINA-9910585945403321 |
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Hussain Hidayat
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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