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Anticancer Inhibitors
| Anticancer Inhibitors |
| Autore | Fantacuzzi Marialuigia |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (216 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
breast cancer
tamoxifen LY294002 synergism apoptosis cell cycle tea (Camellia sinensis) flowers BTFS A2780/CP70 ovarian cancer cells S phase cell cycle arrest nicotinamide phosphoribosyltransferase NAD+ biosynthesis inhibitor azacyclohexane anticancer drug drug design enthalpy effect NSCLC Cathepsin K cell proliferation cell migration cell invasion mTOR isatin-hydrazones cytotoxicity CDK2 inhibitor ATP competitive inhibitor ADME analysis receptor tyrosine kinases protein-protein interactions protein engineering directed evolution angiogenesis binding affinity agonistic activity saponins phytochemicals tea (Camellia sinensis) flower ovarian cancer autophagy ZMYND8 tumorigenesis epigenetic regulation pro-oncogenic effects tumor suppression tacrine-coumarin derivatives DNA topoisomerases I, II lung carcinoma cells A549 chemotherapy prodrug drug targeting overexpressed enzymes ADC ADEPT GDEPT LEAPT PROTAC cyclin-dependent kinase cancer resistance small molecule inhibitors PROTACs statins pancreatic cancer DNA microarray pitavastatin cerivastatin simvastatin fluvastatin atorvastatin pravastatin HMG-CoA reductase inhibitors |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069203321 |
Fantacuzzi Marialuigia
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biocatalysis and Pharmaceuticals: A Smart Tool for Sustainable Development
| Biocatalysis and Pharmaceuticals: A Smart Tool for Sustainable Development |
| Autore | Alcantara Andres R |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (176 p.) |
| Soggetto topico | Biotechnology |
| Soggetto non controllato |
?-transaminase
7-methyl-2?-deoxyguanosine iodide 7-methylguanine arabinoside iodide 7-methylguanosine iodide Alcalase® alcohol amine transaminases amino acid anti-inflammatory antimuscarinic agents antioxidant activity aqueous solubility asymmetric synthesis bacteria benzoxathiepins biocatalysis biotransamination biotransformations cascade chitinases chitosan oligosaccharides chitosanases cholesterol chondroitin sulfates Cladribine coprostanol deacetylation degree ester hydrolysis esterase extraction glycodiverfication glycosaminoglycan glycosidases glycosyltransferase HPSEC laccase activity lyases MALDI-TOF metabolic pathways microalgae n/a nutraceutical OcUGT1 photooxidation pig liver esterase (PLE) pleiotropic effects polysaccharides purine nucleoside phosphorylase reduction reaction reductive amination Ribavirin rutin oligomers Spirulina statins stereoselective stereoselective synthesis sulfuretin Tecadenoson transglycosylation reaction xanthine oxidase inhibition |
| ISBN | 3-03921-709-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Biocatalysis and Pharmaceuticals |
| Record Nr. | UNINA-9910367748703321 |
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Alcantara Andres R
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fatty Acids and Cardiometabolic Health / Matti Marklund, Jason Wu
| Fatty Acids and Cardiometabolic Health / Matti Marklund, Jason Wu |
| Autore | Marklund Matti |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
coronary artery disease
n-6 fatty acids ischemic heart disease n-3 fatty acids body weight alternatively activated macrophages type 2 cytokines children medium-chain triglyceride fat omega-3 PUFA substitution models obesity EETs arachidonic acid blood pressure Genome-wide association study (GWAS) antioxidant Mediterranean diet Insulin sensitivity PUFA n-3 PUFA long-chain triglyceride fish oil omega 3 CAD adipose tissue FADS blood lipids hemodynamics genotype erucic acid klotho CYP450 eicosanoids cardiometabolic disease fibrosis desaturase EEQs cohort study lipid metabolism fatty acid metabolic disease epidemiology omega-3 inflammation docosapentaenoic acid omega-6 PUFA type 2 diabetes mellitus diet CKD human perivascular adipose tissue seafood cardiovascular disease prospective cohort study linoleic acid low-fat diet conjugated fatty acids furan fatty acids unsaturated fat statins fish cholesterol ester CHD COPD |
| ISBN |
9783038978916
3038978914 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346838103321 |
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Marklund Matti
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Matrix Metalloproteinases in Health and Disease
| Matrix Metalloproteinases in Health and Disease |
| Autore | Serra Raffaele |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (196 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
acute kidney injury
adhesion apoptosis arterial aneurysms autoantibodies biomarkers Caco-2 CD147 cGMP chronic kidney disease CKD collagenases Crohn's disease dental caries dialysis disease eGFR eNOS fibrosis genetic association health high-flux dialysis hypersensitivity pneumonitis inflammation inflammatory bowel disease iNOS integrin αMβ2 ischemia/reperfusion kidney transplantation leukocytes Mac-1 MAPKs matrix metalloproteinase matrix metalloproteinase-7 matrix metalloproteinase-9 matrix metalloproteinases metalloproteinases MMP-9 MMP1 MMP2 MMPs mouth NGAL NO on-line hemodiafiltration PAD patients periodontitis peripheral vascular disease platelets proteinuria RECK renal replacement therapy SNPs statins synthetic inhibitors TIMP TIMPs |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557409503321 |
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Serra Raffaele
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neurotransmitter-Related Molecular Modeling Studies
| Neurotransmitter-Related Molecular Modeling Studies |
| Autore | Nowaczyk Alicja |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (188 p.) |
| Soggetto topico |
Chemistry
Research & information: general |
| Soggetto non controllato |
3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors
5-HT receptors acetylcholine adverse drug reaction androgenetic alopecia antibiotics atheroprotection BDNF cardiac voltage-gated ion channels chronic heart failure (CHF) cognitive impairment dementia depression dopamine dysautonomia ECG study gastrointestinal tract genetic polymorphisms glutamate guanylate cyclase (GC) halogenated pyrazolines inflammation kinetics levodopa mixed dyslipidemia molecular dynamics molecular modeling monoamine oxidase inhibitors mouse mTOR neurodegenerative diseases neuroprotection neurotoxicity neurotransmission neurotransmitters orthostatic hypotension oxidative stress pulmonary arterial hypertension (PAH) renin-angiotensin system reserpine-induced fibromyalgia model reversibility risk factors ropinirole serotonin serotonin and dopamine in fibromyalgia SGLT2i sodium-glucose cotransporter 2 inhibitors statins stroke tiagabine type 2 diabetes mellitus vortioxetine white matter hyperintensities |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213903321 |
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Nowaczyk Alicja
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Lipid Lowering Therapies For Cardiovascular and Metabolic Diseases : : Lessons From The Past and Future Challenges / / Ahmed Bakillah
| New Lipid Lowering Therapies For Cardiovascular and Metabolic Diseases : : Lessons From The Past and Future Challenges / / Ahmed Bakillah |
| Autore | Bakillah Ahmed |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (116 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
apolipoprotein
lipids risk stratification proprotein convertase subtilisin-kexin type 9 (PCSK9) vaspin sphingolipids PCSK9 ceramides atrial fibrillation circular RNA STEMI cholesterol lipoproteins cardiovascular disease (CVD) coronary artery bypass grafting atherosclerosis statin LDL subfractions acute kidney injury dyslipidemia gene expression NSTEMI NAFLD hyperlipidemia nonstatin cholesteryl ester transfer protein low-density lipoprotein cholesterol anacetrapib HDL acute coronary syndrome miRNA cardiovascular risk pleiotropic actions genetic ABCA1 sdLDL cardiovascular disease proprotein convertase subtilisin/kexin type 9 inclisiran reverse cholesterol transport sterol small interfering RNA (siRNA) RNA-binding proteins cardiovascular diseases NASH low-density lipoprotein-cholesterol (LDL-C) stroke nutrigenetics type 2 diabetes statins sphingomyelin hepatic fibrosis diabetes |
| ISBN |
9783039216772
3039216775 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367751903321 |
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Bakillah Ahmed
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Technologies for the Treatment of Coronary and Structural Heart Diseases
| New Technologies for the Treatment of Coronary and Structural Heart Diseases |
| Autore | Polimeni Alberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (352 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
2D transesophageal echocardiography
3D transesophageal echocardiography accelerated atherosclerosis ACURATE neo acute coronary syndrome acute myocardial infarction angioplasty antiplatelet aortic stenosis aortic valvuloplasty atherosclerosis bifurcations bilateral internal mammary artery bioresorbable scaffold bioresorbable vascular scaffold borderline lesions cardiac computed tomography cardiac magnetic resonance cardiac magnetic resonance imaging cardiac surgery cardiogenic shock carotid intima-media thickness cholesterol chronic total occlusion clinical implications computerized tomography congenital heart disease coronary artery bypass coronary artery bypass grafting coronary artery disease coronary calcium scoring coronary CT angiography da Vinci diagnosis distal radial drug eluting stents drug-eluting stent dual antiplatelet therapy FDG feature tracking fluorodeoxyglucose positron emission tomography heart failure HIV infection inflammation late gadolinium enhancement left atrial appendage left main longitudinal axis strain low risk magnetic resonance angiography mechanical circulatory support meta-analysis myocardial deformation nonsignificant lesions off-pump coronary artery bypass on-pump coronary artery bypass open heart optical coherence tomography outcome patient selection percutaneous coronary intervention percutaneous coronary interventions PET progenitor cells prognostic evaluation pulmonary hypertension radial re-occlusion regeneration right heart catheterization SAPIEN 3 SAVR severe aortic stenosis snuffbox statins stem cells stent bioresorbable stent thrombosis sternotomy strain structural heart disease STS subclinical coronary artery disease surveillance coronary angiography systemic disease tagging target vessel failure TAVI TAVR transcatheter aortic valve replacement ulnar WATCHMAN occlusive device young patients |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557107503321 |
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Polimeni Alberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Therapies of Liver Diseases
| New Therapies of Liver Diseases |
| Autore | Toniutto Pierluigi |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (236 p.) |
| Soggetto topico | Public health and preventive medicine |
| Soggetto non controllato |
acute-on-chronic liver failure
acute-on-chronic liver failure (ACLF) alcoholic hepatitis alpha-fetoprotein ammonia anti-mineralocorticoids antivirals ascites autoantibodies bleeding cholangiocarcinoma cirrhosis cirrhotic ascites clinical trials colorectal cancer metastases decompensated cirrhosis decompensation effective hypovolemia Farnesoid X Receptor (FXR) agonist functional cure furosemide HBV HDV hepatocellular carcinoma human albumin humoral response immunosuppressant immunotherapy infection liver cancer liver injury liver transplantation liver transplantation (LT) loop diuretics Milan criteria n/a non-selective beta-blockers Pan-Peroxisome Proliferator-Activated Receptor (PPAR) agonists pharmacology portal hypertension portal-systemic shunt primary biliary cholangitis primary biliary cholangitis (PBC) primary sclerosing cholangitis (PSC) real-world rifaximin SARS-CoV-2 second line therapy solid organ transplantation statins survival survival rate systemic treatment targeted therapy TIPS tolvaptan treatment response unresectable hepatocellular carcinoma ursodeoxycholic acid ursodeoxycholic acid (UDCA) vaccination vaptans varices vigilance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566457403321 |
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Toniutto Pierluigi
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Renal Cell Carcinoma
| Renal Cell Carcinoma |
| Autore | López José I |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (500 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
11) translocation renal cell carcinoma
ALK AMP-activated protein kinases anaplastic lymphoma kinase rearrangement aurora A biomarker cancer immunotherapy cancer-specific survival CDKN1A expression checkpoint inhibitors chromophobe renal cell carcinoma chromosomal loss chronic kidney disease circular RNAs in a clinico-genomic predictive model clear cell renal cell carcinoma clear cell Renal Cell Carcinoma collecting duct carcinoma copy number alteration copy number analysis copy number loss curcumin cytoreductive nephrectomy diagnostic and prognostic markers drug sensitivity efficacy emerging entity EMT like eosinophilic variant ESC everolimus EVI1 experimental validation of circular RNA FISH FOXO3 gene expression gene signature genetic association ghrelin glutathione metabolism glutathione transferase omega 1 glutathione transferase omega 2 glycomarkers glycoproteomics HOT hyperosmolality identification of circular RNAs IL-1? IL-2 IL13R?1 IL4R? immune checkpoint inhibitors immune infiltration immunohistochemistry immunotherapy inflammation markers integrins intratumour heterogeneity invasion JAK2 kidney kidney cancer label-free LOT metabolic reprogramming metabolome metabolome profiling metastasis metastatic ccRCC microRNA miR-133b miR-146a-5p miR-155-5p MiT family translocation renal cell carcinoma MMP-9 MMP10 molecular genetic features MTA2 mTOR mTOR inhibitors mutation N-glycomapping n/a nephrectomy new entity NK cells oncocytic renal tumor overall survival pale cell Papillary renal cell carcinoma (pRCC) patient survival PBRM1 PD-L1 pentose phosphate pathway PI3K/Akt/mTOR polybromo-1 polymorphism PPP practical approach predictive factors predictive role pro-IL-1? prognosis prognostic factors programmed death-ligand 1 proliferation proteome profiling Raf/MEK/ERK RCC recurrence free survival recurrence-free survival renal cancer renal cell renal cell cancer renal cell carcinoma review RNA sequencing sarcomatoid SMAD proteins solute carrier proteins statins survival survival prediction t(6 targeted therapy TCA cycle TCGA TFE3 TFEB TFEB-amplified renal cell carcinoma toxicity transforming growth factor beta tumor adhesion tumor microenvironment tumor migration tumor slice culture tyrosine kinase inhibitors unclassified renal cell carcinoma unclassified renal tumor uric acid urine VEGF inhibitors von Hippel-Lindau Xp11 translocation renal cell carcinoma |
| ISBN | 3-03928-639-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087003321 |
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López José I
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Prevention and Treatment of Atherosclerosis
| The Prevention and Treatment of Atherosclerosis |
| Autore | Kabłak-Ziembicka Anna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (150 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
acute myocardial infarction
atherosclerosis atherosclerosis prevention cardiovascular disease cardiovascular risk cardiovascular risk factors carotid intima-media complex carotid plaque cigarette smoking control-theoretic model coronary artery disease Coronary Artery Surgery Study Score coronary computed tomography angiography degenerative aortic stenosis early detection familial hypercholesterolemia fibrin clot fibrinolysis Framingham genetic screening heart failure high-risk plaque intima media thickness intravascular imaging logistic growth major adverse cardiac and cerebral events major cardiac and cerebral ischemic events males malondialdehyde low-density lipoprotein miR-27b myocardial infarction n/a peripheral artery disease prevention PROCAM pulse wave velocity QRISK risk stratification SCORE scores statin statins subclinical atherosclerosis thromboembolism vascular resistance vitamin D |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566472203321 |
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Kabłak-Ziembicka Anna
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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