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Anticancer Inhibitors
| Anticancer Inhibitors |
| Autore | Fantacuzzi Marialuigia |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (216 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
breast cancer
tamoxifen LY294002 synergism apoptosis cell cycle tea (Camellia sinensis) flowers BTFS A2780/CP70 ovarian cancer cells S phase cell cycle arrest nicotinamide phosphoribosyltransferase NAD+ biosynthesis inhibitor azacyclohexane anticancer drug drug design enthalpy effect NSCLC Cathepsin K cell proliferation cell migration cell invasion mTOR isatin-hydrazones cytotoxicity CDK2 inhibitor ATP competitive inhibitor ADME analysis receptor tyrosine kinases protein-protein interactions protein engineering directed evolution angiogenesis binding affinity agonistic activity saponins phytochemicals tea (Camellia sinensis) flower ovarian cancer autophagy ZMYND8 tumorigenesis epigenetic regulation pro-oncogenic effects tumor suppression tacrine-coumarin derivatives DNA topoisomerases I, II lung carcinoma cells A549 chemotherapy prodrug drug targeting overexpressed enzymes ADC ADEPT GDEPT LEAPT PROTAC cyclin-dependent kinase cancer resistance small molecule inhibitors PROTACs statins pancreatic cancer DNA microarray pitavastatin cerivastatin simvastatin fluvastatin atorvastatin pravastatin HMG-CoA reductase inhibitors |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069203321 |
Fantacuzzi Marialuigia
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biocatalysis and Pharmaceuticals: A Smart Tool for Sustainable Development
| Biocatalysis and Pharmaceuticals: A Smart Tool for Sustainable Development |
| Autore | Alcantara Andres R |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (176 p.) |
| Soggetto non controllato |
biotransformations
glycosidases bacteria OcUGT1 antioxidant activity glycodiverfication benzoxathiepins coprostanol 7-methylguanosine iodide sulfuretin chondroitin sulfates 7-methylguanine arabinoside iodide 7-methyl-2?-deoxyguanosine iodide microalgae chitosan oligosaccharides deacetylation degree cholesterol Tecadenoson esterase metabolic pathways chitinases alcohol transglycosylation reaction MALDI-TOF photooxidation aqueous solubility ?-transaminase cascade nutraceutical antimuscarinic agents extraction rutin oligomers Alcalase® HPSEC Cladribine purine nucleoside phosphorylase pleiotropic effects biotransamination amino acid stereoselective laccase activity biocatalysis Ribavirin lyases chitosanases anti-inflammatory glycosaminoglycan polysaccharides amine transaminases ester hydrolysis Spirulina asymmetric synthesis reductive amination glycosyltransferase statins stereoselective synthesis xanthine oxidase inhibition reduction reaction pig liver esterase (PLE) |
| ISBN | 3-03921-709-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Biocatalysis and Pharmaceuticals |
| Record Nr. | UNINA-9910367748703321 |
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Alcantara Andres R
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fatty Acids and Cardiometabolic Health
| Fatty Acids and Cardiometabolic Health |
| Autore | Wu Jason |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (202 p.) |
| Soggetto non controllato |
coronary artery disease
n-6 fatty acids ischemic heart disease n-3 fatty acids body weight alternatively activated macrophages type 2 cytokines children medium-chain triglyceride fat omega-3 PUFA substitution models obesity EETs arachidonic acid blood pressure Genome-wide association study (GWAS) antioxidant Mediterranean diet Insulin sensitivity PUFA n-3 PUFA long-chain triglyceride fish oil omega 3 CAD adipose tissue FADS blood lipids hemodynamics genotype erucic acid klotho CYP450 eicosanoids cardiometabolic disease fibrosis desaturase EEQs cohort study lipid metabolism fatty acid metabolic disease epidemiology omega-3 inflammation docosapentaenoic acid omega-6 PUFA type 2 diabetes mellitus diet CKD human perivascular adipose tissue seafood cardiovascular disease prospective cohort study linoleic acid low-fat diet conjugated fatty acids furan fatty acids unsaturated fat statins fish cholesterol ester CHD COPD |
| ISBN | 3-03897-891-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346838103321 |
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Wu Jason
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Matrix Metalloproteinases in Health and Disease
| Matrix Metalloproteinases in Health and Disease |
| Autore | Serra Raffaele |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
hypersensitivity pneumonitis
metalloproteinases genetic association autoantibodies MMP1 MMP2 SNPs MMPs TIMPs CKD peripheral vascular disease biomarkers proteinuria eGFR PAD NGAL statins arterial aneurysms patients collagenases Crohn’s disease dental caries mouth periodontitis matrix metalloproteinase-9 dialysis on-line hemodiafiltration high-flux dialysis renal replacement therapy kidney transplantation Mac-1 CD147 leukocytes platelets adhesion integrin αMβ2 matrix metalloproteinases TIMP synthetic inhibitors RECK matrix metalloproteinase MAPKs ischemia/reperfusion eNOS iNOS inflammatory bowel disease inflammation NO MMP-9 cGMP Caco-2 matrix metalloproteinase-7 fibrosis acute kidney injury chronic kidney disease apoptosis health disease |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557409503321 |
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Serra Raffaele
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neurotransmitter-Related Molecular Modeling Studies
| Neurotransmitter-Related Molecular Modeling Studies |
| Autore | Nowaczyk Alicja |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
white matter hyperintensities
dysautonomia genetic polymorphisms dementia levodopa renin-angiotensin system orthostatic hypotension reserpine-induced fibromyalgia model vortioxetine ropinirole serotonin and dopamine in fibromyalgia mouse dopamine acetylcholine glutamate BDNF serotonin neurotransmitters statins neurodegenerative diseases stroke depression androgenetic alopecia 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors mixed dyslipidemia risk factors halogenated pyrazolines monoamine oxidase inhibitors kinetics reversibility molecular dynamics guanylate cyclase (GC) chronic heart failure (CHF) pulmonary arterial hypertension (PAH) tiagabine cardiac voltage-gated ion channels molecular modeling ECG study SGLT2i sodium-glucose cotransporter 2 inhibitors neuroprotection atheroprotection mTOR type 2 diabetes mellitus cognitive impairment inflammation oxidative stress antibiotics neurotoxicity adverse drug reaction neurotransmission 5-HT receptors gastrointestinal tract |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213903321 |
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Nowaczyk Alicja
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Lipid Lowering Therapies for Cardiovascular and Metabolic Diseases: Lessons from the Past and Future Challenges
| New Lipid Lowering Therapies for Cardiovascular and Metabolic Diseases: Lessons from the Past and Future Challenges |
| Autore | Bakillah Ahmed |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (116 p.) |
| Soggetto non controllato |
apolipoprotein
lipids risk stratification proprotein convertase subtilisin-kexin type 9 (PCSK9) vaspin sphingolipids PCSK9 ceramides atrial fibrillation circular RNA STEMI cholesterol lipoproteins cardiovascular disease (CVD) coronary artery bypass grafting atherosclerosis statin LDL subfractions acute kidney injury dyslipidemia gene expression NSTEMI NAFLD hyperlipidemia nonstatin cholesteryl ester transfer protein low-density lipoprotein cholesterol anacetrapib HDL acute coronary syndrome miRNA cardiovascular risk pleiotropic actions genetic ABCA1 sdLDL cardiovascular disease proprotein convertase subtilisin/kexin type 9 inclisiran reverse cholesterol transport sterol small interfering RNA (siRNA) RNA-binding proteins cardiovascular diseases NASH low-density lipoprotein-cholesterol (LDL-C) stroke nutrigenetics type 2 diabetes statins sphingomyelin hepatic fibrosis diabetes |
| ISBN | 3-03921-677-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | New Lipid Lowering Therapies for Cardiovascular and Metabolic Diseases |
| Record Nr. | UNINA-9910367751903321 |
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Bakillah Ahmed
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Technologies for the Treatment of Coronary and Structural Heart Diseases
| New Technologies for the Treatment of Coronary and Structural Heart Diseases |
| Autore | Polimeni Alberto |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (352 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
left atrial appendage
WATCHMAN occlusive device 2D transesophageal echocardiography 3D transesophageal echocardiography computerized tomography atherosclerosis cholesterol FDG inflammation PET statins coronary artery bypass on-pump coronary artery bypass off-pump coronary artery bypass young patients severe aortic stenosis longitudinal axis strain late gadolinium enhancement cardiac magnetic resonance imaging optical coherence tomography percutaneous coronary interventions borderline lesions nonsignificant lesions left main bifurcations bilateral internal mammary artery coronary artery disease coronary artery bypass grafting da Vinci sternotomy outcome stent thrombosis bioresorbable scaffold drug eluting stents stent bioresorbable congenital heart disease cardiac surgery open heart progenitor cells regeneration stem cells subclinical coronary artery disease accelerated atherosclerosis HIV infection carotid intima-media thickness coronary calcium scoring coronary CT angiography magnetic resonance angiography fluorodeoxyglucose positron emission tomography mechanical circulatory support percutaneous coronary intervention cardiogenic shock acute myocardial infarction patient selection right heart catheterization pulmonary hypertension heart failure diagnosis prognostic evaluation clinical implications systemic disease cardiac computed tomography cardiac magnetic resonance feature tracking tagging myocardial deformation strain radial ulnar distal radial snuffbox aortic valvuloplasty dual antiplatelet therapy antiplatelet structural heart disease bioresorbable vascular scaffold drug-eluting stent angioplasty acute coronary syndrome chronic total occlusion target vessel failure re-occlusion surveillance coronary angiography meta-analysis ACURATE neo SAPIEN 3 transcatheter aortic valve replacement TAVR TAVI low risk STS aortic stenosis SAVR |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557107503321 |
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Polimeni Alberto
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Therapies of Liver Diseases
| New Therapies of Liver Diseases |
| Autore | Toniutto Pierluigi |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (236 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
tolvaptan
cirrhotic ascites survival rate furosemide primary biliary cholangitis autoantibodies ursodeoxycholic acid treatment response second line therapy primary biliary cholangitis (PBC) primary sclerosing cholangitis (PSC) clinical trials ursodeoxycholic acid (UDCA) Farnesoid X Receptor (FXR) agonist Pan-Peroxisome Proliferator-Activated Receptor (PPAR) agonists liver cancer systemic treatment immunotherapy real-world unresectable hepatocellular carcinoma cirrhosis decompensation bleeding varices survival infection alcoholic hepatitis acute-on-chronic liver failure cholangiocarcinoma colorectal cancer metastases hepatocellular carcinoma liver transplantation Milan criteria alpha-fetoprotein solid organ transplantation liver injury immunosuppressant SARS-CoV-2 humoral response vaccination portal-systemic shunt ammonia vigilance HBV HDV antivirals functional cure pharmacology acute-on-chronic liver failure (ACLF) liver transplantation (LT) decompensated cirrhosis portal hypertension ascites non-selective beta-blockers TIPS rifaximin human albumin statins targeted therapy effective hypovolemia anti-mineralocorticoids loop diuretics vaptans |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566457403321 |
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Toniutto Pierluigi
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Renal Cell Carcinoma
| Renal Cell Carcinoma |
| Autore | López José I |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (500 p.) |
| Soggetto topico |
Renal cell carcinoma
Kidneys - Cancer |
| Soggetto non controllato |
N-glycomapping
SMAD proteins patient survival pro-IL-1? survival prediction inflammation markers tumor migration prognostic factors practical approach circular RNAs in a clinico-genomic predictive model glycomarkers review nephrectomy uric acid VEGF inhibitors metabolic reprogramming collecting duct carcinoma curcumin metabolome profiling identification of circular RNAs IL-2 experimental validation of circular RNA Raf/MEK/ERK HOT PI3K/Akt/mTOR pentose phosphate pathway kidney cancer LOT mutation RCC polybromo-1 pale cell MMP-9 gene expression recurrence free survival chromosomal loss IL-1? chronic kidney disease glutathione transferase omega 2 label-free glutathione transferase omega 1 emerging entity copy number alteration FOXO3 predictive role tumor slice culture tyrosine kinase inhibitors PPP ESC CDKN1A expression metastasis PD-L1 diagnostic and prognostic markers EVI1 copy number loss RNA sequencing NK cells glutathione metabolism clear cell renal cell carcinoma renal cell cancer proliferation eosinophilic variant Xp11 translocation renal cell carcinoma prognosis invasion immune infiltration IL4R? FISH 11) translocation renal cell carcinoma tumor microenvironment metabolome hyperosmolality toxicity ALK drug sensitivity t(6 copy number analysis urine genetic association polymorphism solute carrier proteins kidney metastatic ccRCC molecular genetic features recurrence-free survival chromophobe renal cell carcinoma unclassified renal tumor overall survival mTOR inhibitors mTOR JAK2 von Hippel-Lindau miR-155-5p glycoproteomics PBRM1 miR-133b survival TFE3 TFEB oncocytic renal tumor immune checkpoint inhibitors biomarker MMP10 TCGA ghrelin EMT like checkpoint inhibitors MiT family translocation renal cell carcinoma gene signature sarcomatoid transforming growth factor beta clear cell Renal Cell Carcinoma tumor adhesion renal cancer unclassified renal cell carcinoma Papillary renal cell carcinoma (pRCC) miR-146a-5p renal cell everolimus integrins cytoreductive nephrectomy immunotherapy predictive factors immunohistochemistry MTA2 IL13R?1 targeted therapy intratumour heterogeneity aurora A TCA cycle AMP-activated protein kinases cancer-specific survival programmed death-ligand 1 efficacy renal cell carcinoma anaplastic lymphoma kinase rearrangement TFEB-amplified renal cell carcinoma statins cancer immunotherapy microRNA new entity proteome profiling |
| ISBN | 3-03928-639-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087003321 |
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López José I
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Prevention and Treatment of Atherosclerosis
| The Prevention and Treatment of Atherosclerosis |
| Autore | Kabłak-Ziembicka Anna |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (150 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
familial hypercholesterolemia
genetic screening atherosclerosis prevention early detection atherosclerosis cigarette smoking miR-27b peripheral artery disease subclinical atherosclerosis SCORE Framingham QRISK PROCAM cardiovascular risk pulse wave velocity intima media thickness malondialdehyde low-density lipoprotein high-risk plaque coronary computed tomography angiography statin cardiovascular risk factors heart failure major cardiac and cerebral ischemic events degenerative aortic stenosis risk stratification vascular resistance cardiovascular disease acute myocardial infarction intravascular imaging statins control-theoretic model logistic growth coronary artery disease fibrin clot fibrinolysis thromboembolism carotid intima-media complex carotid plaque major adverse cardiac and cerebral events prevention scores vitamin D myocardial infarction males Coronary Artery Surgery Study Score |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566472203321 |
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Kabłak-Ziembicka Anna
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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