Animal model studies on viral infections [[electronic resource] /] / Topic editors: Akio Adachi and Tomoyuki Miura |
Autore | Tomoyuki Miura |
Pubbl/distr/stampa | Frontiers Media SA, 2015 |
Descrizione fisica | 1 online resource (173 pages) : illustrations; digital, PDF file(s) |
Collana |
Frontiers research topics
Frontiers in microbiology |
Soggetto topico |
Microbiology
Virus diseases - Pathogenesis Virology - Research |
Soggetto non controllato |
viral replication
animal models viral infections anti-viral strategies viral pathogenicity |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Animal model studies on viral infections --Animal models for human Herpesvirus 6 infection --Animal models for Ebola and Marburg virus infections --Hepatitis C virus infection and related liver disease: the quest for the best animal model --Can non-human primates serve as models for investigating Dengue disease pathogenesis? --A transgenic mouse model of human T cell Leukemia virus type-1 associated diseases --Mechanisms of pathogenesis induced by bovine leukemia virus as a model for human T-cell leukemia virus --Macaques as model hosts for studies of HIV-1 infection --Macaque-tropic Human Immunodeficiency Virus type 1: breaking out of the host restriction factors --Genetic similarity of circulating and small intestinal virus at the end stage of acute pathogenic Simian-Human Immunodeficiency Virus infection --A novel but simple method for generation of human dendritic cells from unfractionated peripheral blood mononuclear cells within 2 days: its application for induction of HIV-1-reactive CD4⁺ T cells in the hu-PBL SCID mice --Growth potentials of CCR5-Tropic/CXCR4-Tropic HIV-1mt clones in macaque cells --Sensitive detection of measles virus infection in the blood and tissues of humanized mouse by one-step quantitative RT-PCR --Quantification of viral infection dynamics in animal experiments --Transgenic expression of the human LEDGF/p75 gene relieves the species barrier against HIV-1 infection in mouse cells --Increased infectivity in human cells and resistant to antibody-mediated neutralization by truncation of the SIV gp41 cytoplasmic tail --Natural infection of murine novovirus in conventional and specific pathogen free laboratory mice --HPV18 E1̂ˆ̂E4 is assembled into aggresome-like compartment and involved in sequestration of viral oncoproteins. |
Record Nr. | UNINA-9910136287303321 |
Tomoyuki Miura
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Frontiers Media SA, 2015 | ||
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Lo trovi qui: Univ. Federico II | ||
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New Advances on Zika Virus Research |
Autore | Martinez-Sobrido Luis |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
Descrizione fisica | 1 electronic resource (552 p.) |
Soggetto non controllato |
microRNAs
antivirals reverse genetics nucleic acid computation viral pathogenesis plaque reduction neutralization test clinical trials viral genetic variation viral fitness pregnancy type I IFN antagonist prM-E proteins eye replicon antiviral responses Bacterial artificial chromosome gene expression NS1 protein viral permissiveness ZIKV–host interactions reporter virus viral persistence blood-retinal barrier virus like particles emerging arbovirus Non-human primates heme-oxygenase 1 mosquito surveillance antiviral compounds ZIKV-associated neurologic disorders external quality assessment outbreak control therapeutics cryptic promoter silencing testis neurons mutagenesis RNA-seq microsphere immunoassay host-directed antivirals molecular diagnostics Bayesian analyses astrocytomas Full-length cDNA infectious clones viral pathogenicity neural progenitor cells full-length molecular clone antiviral multiplex nucleic acid detection Asian-lineage nucleic acid strand exchange IgA African-lineage vaccines Zika research models and tools immune response IgG avidity tests polymerase chain reaction Asian lineage sexual transmission TLR7/8 neuropathogenesis cross-reactions genetic variability mosquito ZIKV infectious cDNA prostate host genetic variation monoclonal antibodies optimised anti-viral immunity QCMD arbovirus FSS13025 MR766 NS5 EQA testicular cells virus attachment flavivirus mosquito-borne flavivirus dsRNA boolean logic-processing nucleic acid probes Ziks virus viral replication Aedes aegypti infection natural history infectious RNA zika virus chimeric viruses subgenomic replicon replication human brain glial cells microglia cells hepatocytes bacterial artificial chromosome detoxification and immune system responses testes dengue viruses Zika virus insecticide resistance NS2A protein plasmid toxicity cell surface receptors serology viral evolution laboratory preparedness flaviviruses Tet-inducible dengue virus diagnosis assay standardization infectious clone ELISA innate response congenital Zika syndrome secondary infections apoptosis viral survival ocular validated rhesus macaques neuroinflammation placenta cells NHP Zika virus (ZIKV) point-of-care diagnostics isothermal nucleic acid amplification microcephaly cytopathic effects indirect immunofluorescence fetal infection therapy siRNA viral counteraction neural cells silvestrol eIF4A |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910346661103321 |
Martinez-Sobrido Luis
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MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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