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Advances in Lipidomics: Biomedicine, Nutrients and Methodology
| Advances in Lipidomics: Biomedicine, Nutrients and Methodology |
| Autore | Montero Olimpio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
chronic kidney disease
leptin fatty acids adipose tissue adipocytes adipogenesis differential mobility spectrometry (DMS) lipidomics lipidyzer mass spectrometry metabolomics phenotyping Simpson-Golabi-Behmel syndrome (SGBS) COX CYP450 LOX oxylipins PUFAs UPLC-MS/MS copper Wilson’s disease lipidomic liquid chromatography tandem mass spectrometry molecular network dry eye disease hyperosmolarity cardiovascular disease heart failure myocardial infarction obesity diabetic cardiomyopathy dilated cardiomyopathy lipids odd chain lipids lipid profiling Folch protein precipitation sample preparation relative lipid composition (Mol%) atopic dermatitis SHARPIN-deficient mice flow-injection mass-spectrometry predictive elastic net immunotherapy cancer biomarkers metabolism cancer cell membranes fatty acid biosynthesis essential fatty acids desaturase enzymes fatty acid signaling fatty acid biomarker sapienic acid sebaleic acid molecular nutrition inflammation drug-induced liver injury biomarker plasma lipid profiles ssRNA+ virus membrane fusion lipid metabolism cholesterol sphingolipids phosphatidylinositol SARS-CoV glycolipidomics GIPC glycosyl inositol phospho ceramides Lipid Data Analyzer ultra-high pressure liquid chromatography high-resolution mass spectrometry LC-MS automated annotation |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Advances in Lipidomics |
| Record Nr. | UNINA-9910557497303321 |
Montero Olimpio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antiviral Agents
| Antiviral Agents |
| Autore | Adamson Catherine |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (386 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Zika virus
nucleoside analogues antiviral agents NS5 prodrugs ProTides neural stem cells RNA-dependent RNA polymerase cytomegalovirus latent infection TALEN Surveyor nuclease mutation detection assay ie-1 gene quantitative real-time PCR Epstein-Barr virus herpes viruses lytic gene expression Burkitt lymphoma cells clozapine antipsychotic drug antiviral drug enteroviruses coxsackievirus B4 persistent infection fluoxetine resistance mutations herpes B virus macacine herpesvirus-1 genistein flavonoids acyclovir ganciclovir Plantago asiatica Clerodendrum trichotomum RSV therapeutic effects acteoside human antimicrobial peptides antiviral strategies defensins cathelicidins hepcidins transferrins influenza A virus brevilin A antiviral sesquiterpene lactone replication PRRSV polyethylenimine PEI virion internalization endocytosis HIV pediatrics Ethiopia pre-treatment drug resistance combination antiretroviral therapy (cART) dried plasma spots dried blood spots sphingolipids glycosphingolipids viruses lipid biosynthesis flavivirus Japanese encephalitis virus furin inhibitor precursor membrane protein measles virus central nervous system tropism treatments porcine reproductive and respiratory syndrome virus ginsenoside Rg1 antiviral activity pro-inflammatory factor NF-κB signaling pathway acute/latent infection congenital infection antiviral agent therapeutic strategies nucleic acid-based therapeutic approach HCMV vaccine adoptive cell therapy Rev response element chemical footprinting SHAPE drug discovery branched peptides herpesvirus immediate-early IE1 IE2 ribozyme RNA interference CRISPR/Cas small molecule orthohantavirus phenyl-benzotriazoles C-FRA Porcine circovirus type 2 epigallocatechin gallate heparan sulfate antiviral effect virus attachment microvirin lectin human immunodeficiency virus hepatitis C virus antiviral inhibitor non-immunogenic viral entry protein drugs LUMS1 oleanane-type derivatives influenza A virus (IAV) virus entry inhibitors hemagglutinin (HA) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557448703321 |
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Adamson Catherine
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Candida albicans A Major Fungal Pathogen of Humans
| Candida albicans A Major Fungal Pathogen of Humans |
| Autore | Richardson Jonathan |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (182 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Microbiology (non-medical) |
| Soggetto non controllato |
Candida albicans
acridine antifungal topoisomerase inhibitor candidiasis 1,3,4-oxadiazole drug discovery antifungal agents drug resistance toxicity biofilm invasive Candida infections invasive fungal infections antifungal prophylaxis newborns surgery neonatal surgery multivalency anti-adhesion glycoconjugates glycomimetics Candida C. albicans XCL1 metamorphic protein fold-switching protein antifungal peptide polymorphism hyphal morphogenesis hyphal activation signal transduction pathways cell cycle regulation sphingolipids myriocin fungal infections epigenetic yeast chromatin hyphae human fungal pathogen nutrient sensing amino acid metabolism proline catabolism mitochondria SPS-sensor nitrogen catabolite repression glucose repression immunometabolism metabolism macrophages epithelial cells glycolysis glucose moonlighting proteins |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580211203321 |
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Richardson Jonathan
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Echinoderms Metabolites: Structure, Functions and Biomedical Perspectives II
| Echinoderms Metabolites: Structure, Functions and Biomedical Perspectives II |
| Autore | Kalinin Vladimir I |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (192 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
diacylglycerol ether
1-O-alkylglyceryl ether nutraceutical oils bêche-de-mer sea cucumber Bohadschia argus Holothuria (Theelothuria) spinifera fucosylated chondroitinsulfates fucan sulfates anticoagulant activity disulfated steroids NMR spectra starfish Pteraster marsippus cytotoxic activity 3D culture Psolus chitonoides triterpene glycosides chitonoidosides triterpene glycosides membranolytic action hemolytic molecular dynamic simulation Thyonidium kurilensis kurilosides polyhydroxysteroids steroid glycosides lipids mass spectrometry metabolomics metabolomic profiling sphingolipids ceramides cerebrosides gangliosides sialic acid Asteroidea Holothuroidea biological activity neuritogenic activity |
| ISBN | 3-0365-5130-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Echinoderms Metabolites |
| Record Nr. | UNINA-9910619464403321 |
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Kalinin Vladimir I
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Emerging Role of Lipids in Metabolism and Disease
| Emerging Role of Lipids in Metabolism and Disease |
| Autore | Pallottini Valentina |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (308 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
neutral sphingomyelinase
radiation sphingomyelin metabolism pathology cell signaling brain adipose tissue breast cancer epinephrine breast reconstruction epicardial fat thickness visceral fat thickness high-sensitivity c-reactive protein leptin gender female hippocampus frontal cortex adiponectin haptoglobin lipocalin BDNF synaptic proteins phosphatidylinositol 4,5-bisphosphate phospholipase C cholesterol high-cholesterol diet BET proteins cell proliferation epigenetics HMGCR JQ1 LDLr lipid metabolism SREBP TMEM97 atherosclerosis diabetes mellitus cardiovascular disease chronic inflammation hyperglycemia mutations lipid fatty acid glyceride steroid phospholipid oral drug absorption prodrug phospholipase A2 (PLA2) acid sphingomyelinase SOD liver eicosanoids ischemic stroke ischemia lipoproteins polyunsaturated fatty acids angiogenesis high-density lipoprotein endothelial cell metabolism metabolic reprogramming pulmonary fibrosis lipid mediators sphingolipids sphingosine-1-phosphate sphingosine kinase 1 prostaglandins lysophosphatidic acid autotaxin G-protein coupled receptors lysocardiolipin acyltransferase phospholipase D oxidized phospholipids DNA damage response double strand breaks ATM ionizing radiation metabolic stress oxidative stress p53 nuclear sphingolipids lipophagy lipolysis lipid droplets lipid storage diseases lipid metabolism diseases mTORC1 TFEB Cholesterol Fatty acids Lipid mediators Lipids Lipophagy Sphingolipids |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557800303321 |
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Pallottini Valentina
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondrial Dysfunction in Aging and Diseases of Aging
| Mitochondrial Dysfunction in Aging and Diseases of Aging |
| Autore | Haas Richard H |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (270 p.) |
| Soggetto non controllato |
age-related diseases
sphingolipids glaucoma ALS neurodegeneration mitochondrial dysfunction adaptive immunity senescence de-emergence innate immunity cell danger response mitochondrial transfer axonal transport cytokines mitochondrial age-related macular degeneration prevention heart failure purinergic signaling autophagy Alzheimer's disease diabetic retinopathy proteostasis 1 immunosenescence Miro1 ROS metabolism optic nerve polypharmacy eIF2? Parkin coenzyme Q10 neurodegenerative disease DNA damage skin exercise nucleotide metabolism pasteur effect stress response inflammation retina drug-induced mitochondrial toxicity neuroinflammation exosomes reactive oxygen species 25(OH)D cardiomyopathy crabtree effect insulin resistance cardiovascular disease ageing genetic mutations metabokines mitochondria multiple sclerosis aerobic healing cycle SOD1 mitophagy PINK1 type 2 diabetes integrated cell stress response morbidity and mortality ultraviolet photoageing cancer aging 25(OH)2D lysosome NAD+ Parkinson's disease |
| ISBN | 3-03921-328-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756303321 |
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Haas Richard H
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Multi-Omics for the Understanding of Brain Diseases
| Multi-Omics for the Understanding of Brain Diseases |
| Autore | Yoon Jong |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (204 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
schizophrenia
abnormal behavior gene set region differentially expressed genes de novo mutation copy number variant SIDS newborn infant genetic polymorphism neurotransmitter epigenetics epigenome zinc finger domain zinc finger motif zinc finger proteins zinc metalloproteins flow infusion analysis chloride adducts ceramides sphingolipids glycerophosphocholines human brain NAD+ nicotinamide ageing plasma biomarker CNV PPI spatiotemporal network chromosome 22q11.21 DGCR8 Orthosiphon stamineus plant-derived proteins neuroprotective SH-SY5Y cell model hydrogen peroxide CSF miRNAs neurological diseases OpenArray morphine withdrawal brain proteomics synaptic plasticity Alzheimer's disease microfluidics lab-on-chip 3D culture organ-on-chip |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557349303321 |
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Yoon Jong
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Lipid Lowering Therapies for Cardiovascular and Metabolic Diseases: Lessons from the Past and Future Challenges
| New Lipid Lowering Therapies for Cardiovascular and Metabolic Diseases: Lessons from the Past and Future Challenges |
| Autore | Bakillah Ahmed |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (116 p.) |
| Soggetto non controllato |
apolipoprotein
lipids risk stratification proprotein convertase subtilisin-kexin type 9 (PCSK9) vaspin sphingolipids PCSK9 ceramides atrial fibrillation circular RNA STEMI cholesterol lipoproteins cardiovascular disease (CVD) coronary artery bypass grafting atherosclerosis statin LDL subfractions acute kidney injury dyslipidemia gene expression NSTEMI NAFLD hyperlipidemia nonstatin cholesteryl ester transfer protein low-density lipoprotein cholesterol anacetrapib HDL acute coronary syndrome miRNA cardiovascular risk pleiotropic actions genetic ABCA1 sdLDL cardiovascular disease proprotein convertase subtilisin/kexin type 9 inclisiran reverse cholesterol transport sterol small interfering RNA (siRNA) RNA-binding proteins cardiovascular diseases NASH low-density lipoprotein-cholesterol (LDL-C) stroke nutrigenetics type 2 diabetes statins sphingomyelin hepatic fibrosis diabetes |
| ISBN | 3-03921-677-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | New Lipid Lowering Therapies for Cardiovascular and Metabolic Diseases |
| Record Nr. | UNINA-9910367751903321 |
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Bakillah Ahmed
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Placental Related Disorders of Pregnancy
| Placental Related Disorders of Pregnancy |
| Autore | Mistry Hiten D |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (378 p.) |
| Soggetto topico |
Medicine
Physiology |
| Soggetto non controllato |
low-dose aspirin
preeclampsia placenta eicosanoids sphingolipids thromboxane prostacyclin isoprostanes neutrophils protease-activated receptor 1 cold shock protein intrauterine growth restriction placentation apoptosis NF-κB hypertension in pregnancy angiogenesis endothelial function oxidative stress antioxidants post-maturity senescence pre-eclampsia renin-angiotensin system megalin proton pump inhibitors telomere shortening prenatal depression sex differences flow culture system explant culture under flow placental insufficiency SPINT2/HAI-2 foetal growth restriction small for gestational age placentome pregnancy nutrient restriction gene expression transcriptome spontaneous preterm birth bioenergetic metabolism interactome fetal sex disparity CD24 cytotrophoblast syncytiotrophoblast immunohistochemistry quantitative polymerase chain reaction (qPCR) immune tolerance inflammation cytokines adipokines antimicrobial peptides metabolic stress IGF-I insulin lactotroph hormones decidual reaction fetal membranes placental hormones primates uterine spiral artery uterine NK cell chorionic somatomammotropin blood flow nutrient uptake uterus ERAP2 trophoblast cells RNA sequencing differentially expressed genes congenital heart disease hand1 vascular development intrahepatic cholestasis of pregnancy human placenta bile acids transporters pregnancy complications metabolism glycolysis mitochondrial respiration placental metabolism trophoblast glycolysis trophoblast mitochondrial respiration sexual dimorphism Interleukin-15 CD122 natural killer cells macrophages trophoblast Irisin TRPV6 calcium transport skeletal dysplasia serine proteases subunit assembly transient receptor potential antioxidant capacity decidua fetal growth restriction KEAP1 NRF2 |
| ISBN | 3-0365-5899-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639995303321 |
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Mistry Hiten D
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sphingolipids : From Pathology to Therapeutic Perspectives - A Themed Honorary Issue to Prof. Lina Obeid
| Sphingolipids : From Pathology to Therapeutic Perspectives - A Themed Honorary Issue to Prof. Lina Obeid |
| Autore | van Echten-Deckert Gerhild |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (292 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
S1P receptor
inflammation S1P transporter spinster homolog 2 barrier dysfunction anxiety depression sphingolipids sphingomyelinase ceramidase Smpd1 acid sphingomyelinase forebrain depressive-like behavior anxiety-like behavior ceramide ceramides ceramidases neurodegenerative diseases infectious diseases sphingosine 1-phoshate sphingosine 1-phosphate receptor S1P1-5 sphingosine 1-phosphate metabolism sphingosine 1-phosphate antagonistst/inhibitors sphingosine 1-phosphate signaling stroke multiple sclerosis neurodegeneration fingolimod Sphingosine-1-phosphate obesity type 2 diabetes insulin resistance pancreatic β cell fate hypothalamus sphingosine-1-phosphate ischemia/reperfusion cardioprotection vasoconstriction coronary flow myocardial function myocardial infarct albumin type 1 diabetes beta-cells islets insulin cytokines S1P animal models cystic fibrosis autophagy myriocin Aspergillus fumigatus CLN3 disease Cln3Δex7/8 mice flupirtine allyl carbamate derivative apoptosis cancer gangliosides immunotherapy metastasis phenotype switching sphingosine 1-phosphate Sphingosine 1-phosphate (S1P) S1P-lyase (SGPL1) tau calcium histone acetylation hippocampus cortex astrocytes neurons sphingosine kinase G-protein-coupled receptors Gαq/11 sphingosine kinase 1 SK1 microRNA transcription factor hypoxia long non-coding RNA |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Sphingolipids |
| Record Nr. | UNINA-9910557545203321 |
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van Echten-Deckert Gerhild
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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