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Anticancer Drugs 2021
| Anticancer Drugs 2021 |
| Autore | Meegan Mary J |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (594 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
thymidylate synthase
cytotoxicity 1,2,3-triazole 1,3,4-oxadiazole 5-fluoruracil pemetrexed docking 3,4'-bis-guanidino 3-amino-4'-guanidino diphenyl ether phenyl pyridyl ether intramolecular hydrogen bond cancer cell viability HL-60 BRAF apoptosis thieno[2,3-d][1,2,3]triazine acetamide H1299 HER2 EGFR Bcl-2 inhibitors Indole-based analogues benzimidazole MTT cytotoxic assay cell cycle analysis DNA fragmentation ELISA solid/lipid nanoparticles phenstatin letrozole tubulin polymerisation inhibitor aromatase inhibitor breast cancer hybrid molecule dual-targeting molecule designed multiple ligand NaMSA cyclophosphamide histopathology testis urinary bladder anticancer agents enantioselective synthesis gastric adenocarcinoma tryptophanol concentration-guided dosing model informed dosing physiologically based pharmacokinetics sorafenib tyrosil-DNA-phosphodiesterase 1 adamantane resin acid TDP1 cytotoxic agents apoptosis induction HT-29 cells MDA-MB-231 cells mechanism prediction STAT inhibitors miR-21 hydrazide derivatives nitrogen scaffolds mitoxantrone cardiotoxicity inflammation oxidative stress age cumulative dose Trk NTRK tissue-agnostic larotrectinib entrectinib Trk fusion protein kinase inhibitors USFDA cancer patent review generic product doxazosin MD simulations combretastatin A-4 cytotoxic activity hybrid compounds indazole mucin MUC1 MUC16 immunotherapy cancer vaccine CAR (chimeric antigen receptor) ADC (antibody-drug conjugate) thiourea interleukin-6 trypan blue assay chalcones exportin-1 covalent binding CovDock anticancer activity xanthone in vitro in vivo isolation synthesis heterocyclic compound benzenesulfonamides imidazoles alkylated colony formation tumor spheroids HDAC inhibitors chalcone dual inhibitors carvedilol kidney toxicity 7-deaza-4'-thioadenosine derivatives multi-kinase inhibitor anticancer nucleoside Imiquimod drug efflux multidrug resistance Toll-Like Receptor |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576874303321 |
Meegan Mary J
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Coumarin and Its Derivatives
| Coumarin and Its Derivatives |
| Autore | Matos Maria João |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (406 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
coumarin
hydroxyl-modified coumarin photophysical thermal and structural characterization Glycyrrhiza uralensis glycyrol liquiritigenin cholinesterases human monoamine oxidases kinetics docking simulation chalcone neurodegenerative diseases adenosine receptors binding affinity docking 4-hydroxy-7-methoxycoumarin macrophage inflammation NF-κB MAPK calanolides pseudocalanolides calanolide A Calophyllum Calophyllaceae anti-HIV reverse transcriptase non-nucleoside reverse transcriptase inhibitors (NNRTIs) osthole umbelliferone esculin 4-hydroxycoumarin sorafenib apoptosis autophagy Yin Chen Hao constitutive androstane receptor scoparone coumarins quorum sensing QS inhibitors plant-derived molecules Chromobacterium violaceum immunoproteasome psoralen core non-peptidic electrophilic compounds warhead scan inflammatory bowel disease isocoumarin Crohn's disease ulcerative colitis glutathione oxidative stress complementary therapies intestinal inflammation benzopyrones five-membered aromatic heterocycles furan pyrrole thiophene selenophen dihydrocoumarin-fused dihydropyranones 3-aroylcoumarines benzyl 2,3-butadienoate 6'-(4-biphenyl)-β-iso-cinchonine biological applications drug discovery fluorescent probes warfarin acenocoumarol mechanical valve time in therapeutic range anticoagulation Ruta chalepensis Rutaceae chalepin chalepensin bioactivity biosynthesis coumarin3-carboxamides pyranocoumarins anticancer activity antibacterial activity free radical polymerization LED photocomposites direct laser write analytical methods model plant natural genetic variation natural products simple coumarins chalcocoumarin MAO-B molecular dynamics in silico studies dye-sensitized solar cells coumarin dyes thieno [3,2-b] thiophene charge transfer ethynylaryl esculetin antiplatelet activity impedance aggregometry COX polyphenols pyrazole imidazole thiazole oxazole triazole thiadiazole curcumin curcumin-coumarin hybrids neuroprotection monoamine oxidase inhibition cholinesterase inhibition scavenging activity Escherichia coli biotransformation ferulenol structural annotation in silico tools |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557577003321 |
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Matos Maria João
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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PLGA Based Drug Carrier and Pharmaceutical Applications
| PLGA Based Drug Carrier and Pharmaceutical Applications |
| Autore | Pereira Maria Carmo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (328 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
PLGA
nanoscaled drug delivery LED cancer serum stability reactive oxygen species cellular uptake terahertz spectroscopy microspheres drug delivery formulation development molecular mobility vitamin E tocopherol PLA core-shell nanoparticles controlled drug release BMP-2 PLGA nanoparticles Pluronic F68 oxaliplatin hydrogel intra-abdominal anti-adhesion barrier colorectal cancer experimental design fractional factorial design O6-methylguanine DNA methyltransferase (MGMT) protein glioblastoma multiforme smart nanocarriers folic acid verteporfin cisplatin SKOV-3 cells CHO-K1 cells electroporation theranostic cargo double emulsion approach NSAIDs polymeric film topical drug delivery trolamine salicylate triamcinolone acetonide microcrystal PLGA microsphere local delivery spray-drying technique intra-articular injection joint retention systemic exposure gadolinium drug release polymeric nanocarrier sorafenib theranostic nanoparticles PLGA-PEG nanoparticles platelet activation aggregation binding uptake tissue engineering Huntington's disease siRNA microcarriers mesenchymal stromal cells drug delivery systems microfluidics microparticles BMP-2-microspheres hydrogel system 17-βestradiol release bone regeneration osteoporosis poly-lactide-co-glycolide polylactic acid alginate ophthalmic drug delivery dexamethasone PLGA-NPs nanomedicine gastrointestinal tract paclitaxel in vivo imaging controlled release risperidone microcapsules oleogels electron microscopy three-dimensional X-ray imaging nano-CT biodegradable polymers hydroxy-stearic acid PLGA nanocapsules magnetic resonance imaging photoluminescence magnetic targeting multimodal imaging theranostics silicon microsphere |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557124003321 |
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Pereira Maria Carmo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Present and Future of Personalised Medicine for Endocrine Cancers
| Present and Future of Personalised Medicine for Endocrine Cancers |
| Autore | Ronchi Cristina L |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (140 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
papillary thyroid cancer
SUV PET/CT BRAF V600E immune checkpoint inhibitors (ICIs) ipilimumab nivolumab prolactinoma Cushing's disease aggressive pituitary tumor aggressive PitNET aggressive pituitary adenoma pituitary carcinoma adrenocortical cancer adrenal adenomas adrenal tumors p53 p27 ki-67 reticulin mitotane adjuvant treatment recurrence recurrence free survival timing intratumoral heterogeneity thyroid tumor BRAF RET/PTC rearrangements RAS mutation adrenal cortex carcinoma angiogenesis gene expression osteopontin hyaluronan synthase 1 multikinase inhibitors sorafenib lenvatinib differentiated thyroid cancer radioiodine resistance predictive marker predictors response to treatment survival information needs and preferences focus group interview personalized medicine neuroendocrine tumours phaeochromocytoma paraganglioma molecular clusters |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576879703321 |
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Ronchi Cristina L
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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