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Application of Bioinformatics in Cancers
| Application of Bioinformatics in Cancers |
| Autore | Brenner J. Chad |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (418 p.) |
| Soggetto topico | Biotechnology |
| Soggetto non controllato |
activation induced deaminase
AID/APOBEC alternative splicing anti-cancer artificial intelligence bioinformatics Bioinformatics tool biomarker discovery biomarker signature biomarkers biostatistics brain brain metastases breast cancer breast cancer detection breast cancer prognosis Bufadienolide-like chemicals cancer cancer biomarker cancer biomarkers cancer CRISPR cancer modeling cancer prognosis cancer treatment cancer-related pathways cell-free DNA chemotherapy circulating tumor DNA (ctDNA) classification clinical/environmental factors colorectal cancer comorbidity score Computational Immunology concatenated deep feature copy number aberration copy number variation curation curative surgery datasets decision support systems deep learning denoising autoencoders differential gene expression analysis diseases genes DNA DNA sequence profile drug resistance epigenetics erlotinib estrogen extreme learning false discovery rate feature extraction and interpretation feature selection firehose functional analysis gefitinib gene expression analysis gene inactivation biomarkers gene loss biomarkers gene signature extraction genomic instability GEO DataSets head and neck cancer health strengthening herb hierarchical clustering analysis high-throughput analysis histopathological imaging histopathological imaging features HNSCC hormone sensitive cancers HP hTERT imaging independent prognostic power interaction intratumor heterogeneity knockoffs KRAS mutation locoregionally advanced machine learning meta-analysis methylation microarray miRNA miRNAs mitochondrial metabolism mixture of normal distributions molecular mechanism molecular subtypes Monte Carlo mortality multiple-biomarkers mutable motif mutation Neoantigen Prediction network analysis Network Analysis network pharmacology network target neurological disorders next generation sequencing observed survival interval omics omics profiles oral cancer ovarian cancer overall survival pancreatic cancer pathophysiology PD-L1 precision medicine predictive model protein R package RNA self-organizing map single-biomarkers single-cell sequencing skin cutaneous melanoma somatic mutation StAR steroidogenic enzymes survival analysis TCGA TCGA mining telomerase telomeres The Cancer Genome Atlas traditional Chinese medicine transcriptional signatures treatment de-escalation tumor tumor infiltrating lymphocytes tumor microenvironment variable selection |
| ISBN | 3-03921-789-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367743403321 |
Brenner J. Chad
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Hereditary Hemorrhagic Telangiectasia : Recent Advances and Future Challenges
| Hereditary Hemorrhagic Telangiectasia : Recent Advances and Future Challenges |
| Autore | Mager Hans-Jurgen |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (228 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
activin receptor-like kinase 1 (ALK1)
activin-receptor-like kinase 1 ACVRL1 ALK1 angiogenesis antiangiogenic properties anticoagulants antiplatelets antithrombotic therapy arteriovenous malformation arteriovenous malformation (AVM) arteriovenous malformations (AVMs) AVM bazedoxifene bevacizumab biomarker biomarkers bleeding bone morphogenetic protein (BMP) catheter based embolization therapy cell adhesion cerebral ischemic lesions contrast enhanced magnetic resonance angiography endoglin Endoglin endothelial cells ENG epistaxis epistaxis severity score etamsylate FK506 gastrointestinal bleeding genetic disease genotype-phenotype correlation guidelines hereditary hemorrhagic hereditary hemorrhagic telangiectasia Hereditary hemorrhagic telangiectasia Hereditary Hemorrhagic Telangiectasia hereditary hemorrhagic telangiectasia (HHT) hereditary hemorrhagic telangiectasia (HHT), second-hit hereditary hemorrhagic telangiectasia/HHT/osler's disease HHT inflammation life expectancy liver long non-coding RNAs mechanical damage microRNA microRNAs MRI N-acetylcysteine nasal endoscopy nasal ointment non-coding RNAs nosebleeds Osler-Weber-Rendu pediatrics plasma propranolol propranolol gel pulmonary arteriovenous malformation pulmonary arteriovenous malformations raloxifene rare disease rare diseases safety screening shear stress Smad pathway Smad4 SMAD4 somatic mutation sun-induced trauma survival tacrolimus telangiectases telangiectasia telangiectasis tranexamic acid transcatheter embolotherapy transforming growth factor beta (TGF-β) transforming growth factor-beta (TGF-β) ultrasound vascular endothelial growth factor (VEGF) vascular injury vascular malformations |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Hereditary Hemorrhagic Telangiectasia |
| Record Nr. | UNINA-9910557578003321 |
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Mager Hans-Jurgen
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer
| Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer |
| Autore | Nakayama Naomi |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (258 p.) |
| Soggetto topico | Public health and preventive medicine |
| Soggetto non controllato |
adoptive immunotherapy
anti-angiogenic therapy aryl hydrocarbon receptor BEN (BANP, E5R and NAC1) domain biological planning biomarkers borderline ovarian tumors BRCA1 mutant ovarian cancer cancer progression CD44 cervical cancer cervical neoplasia chimeric antigen receptor clear cell carcinoma differentially expressed genes DNA damage response DNA mismatch repair (MMR) drug repurposing endometrial cancer endometrial carcinoma endometrioid endometrial cancer epithelial ovarian cancer epithelial ovarian cancers epithelial-mesenchymal transition exosome gene ontology gynecological cancer HDR brachytherapy human cytomegalovirus immune checkpoints inhibitors immune micro-environment immunohistochemistry immunosuppression in vivo dosimetry inflammation integrative analysis interventional radiotherapy isothermal titration calorimetry (ITC) liquid biopsy long-term survival melanoma treatment microsatellite instability miRNA mismatch repair deficiency MMR deficient (dMMR) n/a nanocarriers NK cells non-coding RNAs nucleus accumbens-associated protein 1 (NAC1) ovarian cancer p16 protein pGSK3β PLA2G7) platelet-activating factor acetylhydrolase (PAF-AH prognosis sequence-specific DNA-binding protein solution NMR structure somatic mutation targeted therapy testin vaginal melanoma vaginal-cuff brachytherapy vulvar melanoma Wnt signaling β-catenin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580209103321 |
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Nakayama Naomi
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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