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Anticancer Inhibitors
| Anticancer Inhibitors |
| Autore | Fantacuzzi Marialuigia |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (216 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
breast cancer
tamoxifen LY294002 synergism apoptosis cell cycle tea (Camellia sinensis) flowers BTFS A2780/CP70 ovarian cancer cells S phase cell cycle arrest nicotinamide phosphoribosyltransferase NAD+ biosynthesis inhibitor azacyclohexane anticancer drug drug design enthalpy effect NSCLC Cathepsin K cell proliferation cell migration cell invasion mTOR isatin-hydrazones cytotoxicity CDK2 inhibitor ATP competitive inhibitor ADME analysis receptor tyrosine kinases protein-protein interactions protein engineering directed evolution angiogenesis binding affinity agonistic activity saponins phytochemicals tea (Camellia sinensis) flower ovarian cancer autophagy ZMYND8 tumorigenesis epigenetic regulation pro-oncogenic effects tumor suppression tacrine-coumarin derivatives DNA topoisomerases I, II lung carcinoma cells A549 chemotherapy prodrug drug targeting overexpressed enzymes ADC ADEPT GDEPT LEAPT PROTAC cyclin-dependent kinase cancer resistance small molecule inhibitors PROTACs statins pancreatic cancer DNA microarray pitavastatin cerivastatin simvastatin fluvastatin atorvastatin pravastatin HMG-CoA reductase inhibitors |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069203321 |
Fantacuzzi Marialuigia
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular Oxidative Stress
| Cellular Oxidative Stress |
| Autore | Marino Angela |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (529 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
neuroinflammation
clinical palmitoylethanolamide luteolin co-ultramicronization CNS pathology adaptive immune response cell homeostasis legumes liver hepatic steatosis lipid dyshomeostasis ROS traumatic brain injury palmitoylethanolamide (PEA) therapeutic strategies oxidative stress RNA-Seq RPE Retinitis pigmentosa A2E diabetes glucose exposure Band 3 protein erythrocytes SO42− 4-hydroxy-2-nonenal 3-glutathionyl-4-hydroxynonanal astrocytoma cells soy soybeans soy foods antioxidants reactive oxygen species cardiovascular diseases cancer paw edema cashew nuts antioxidant inflammation polyphenols analgesic d-Galactose glycation SO42− uptake anion exchange diseases immune system NF-κB cigarette smoke extract nasal fibroblasts tissue inhibitor of metalloproteinases matrix metalloproteinase steroids Plasmodium falciparum syk kinase inhibitors artemisinin derivatives hemichromes cellular redox state mitochondrial function cisplatin nephrotoxicity acute pancreatitis obesity nitrosative stress PGC-1α microparticles vesiculation band 3 tert-Bytyl hydroperoxide t-BOOH nitric oxide donor calcium ionophore A23187 age-related macular degeneration (AMD) diet Substance-P adipose-derived stem cells paracrine factors epilepsy status epilepticus Trolox HeLa prooxidant AVD apoptosis neurodegeneration ncRNA miRNA tRNA fragments lncRNA circRNA preeclampsia hemostasis platelets coagulation fish mucosal immunity nasal immunity peroxide vitamin C NAC immunosenescence T cells vaccination aging microvascular permeability bradykinin interleukin 1β NADPH oxidase simvastatin molecular hydrogen autophagy matrix metalloproteinases reactive oxygen species (ROS) phytochemicals dietary chemicals natural compounds programmed cell death anoikis ferroptosis pyroptosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557338703321 |
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Marino Angela
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Kidney Inflammation, Injury and Regeneration 2020
| Kidney Inflammation, Injury and Regeneration 2020 |
| Autore | Baer Patrick C |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (318 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
inflammation
chronic kidney disease anemia anemia of inflammation ESA hyporesponsiveness renal tubular epithelial cells macrophages lipocalin-2 iron cilastatin hypoxia inducible factor-1-α ischemia-reperfusion injury acute kidney injury cyclophilin A fibrosis renal fibrosis tubular necrosis preeclampsia podocytes VEGF FSGS proteinuria endocan ESM-1 renal replacement therapy kidney transplantation biomarker diabetic nephropathy focal segmental glomerulosclerosis innate immunity membranous nephropathy minimal change diseases TLR NOX1 ML171 reactive oxygen species ERK T cells glomerulonephritis chemokines renal disease DJ-1 ND-13 renal inflammation oxidative stress UUO autophagy apoptosis trehalose simvastatin endotoxin tubular apoptosis cytochrome C Bcl-XL survivin hypercholesterolemia xanthine oxidase NF-κB pathway tertiary lymphoid organs B cells BAFF kidney fibrosis myofibroblast activation extracellular matrix Hippo pathway verteporfin IgAN CKD progression ACEI corticosteroids costimulation coinhibition kidney transplant SPR protein binding affinity adaptive immunity epithelial-to-mesenchymal transition E. cava extracts dieckol spontaneously hypertensive rats angiotensin II |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557364503321 |
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Baer Patrick C
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transmucosal Absorption Enhancers in the Drug Delivery Field
| Transmucosal Absorption Enhancers in the Drug Delivery Field |
| Autore | Maher Sam |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (406 p.) |
| Soggetto non controllato |
chitosan
intestinal epithelial cells ocular delivery amphiphilic polymers cornea tight junction modulator cyclodextrin permeability gemini surfactant transferrin compound 48/80 epithelial permeability cervicovaginal tumors nanoparticles confocal laser scanning microscopy safety formulation salcaprozate sodium intestinal absorption FITC-dextran curcumin block copolymers nasal vaccination whole leaf brush border ocular drug delivery vaccine adjuvant nanoparticle nasal delivery efflux permeation enhancers absorption enhancers nose to brain delivery small intestine epithelium CNS disorders absorption modifying excipients insulin absorption enhancer gel intestinal delivery thermogel system Caco-2 biocompatibility studies absorption enhancement man PN159 poorly absorbed drug tryptophan tight junction oral macromolecule delivery penetration enhancer intestinal permeation enhancers nanocrystals simvastatin nanomedicine enterocyte N-dodecyl-?-D-maltoside (DDM) cell-penetrating peptide quaternization KLAL nasal nasal permeability transmucosal drug delivery Caco-2 cells mast cell activator penetration enhancers drug delivery nose-to-brain bioenhancer polymeric micelles mucoadhesion cell-penetrating peptide (CPP) simulated intestinal fluid vaginal delivery nasal formulation pharmacokinetic interaction sodium caprate clinical trial transmucosal permeation drug absorption enhancer sugar-based surfactants nanocapsules imatinib teriparatide osteoporosis hydrophobization F-actin combined microsphere transepithelial electrical resistance oral delivery ocular conditions metabolism antimicrobial peptide permeation enhancer drug administration antiepileptic drug amino acid in vivo studies sodium cholate (NaC) epithelial transport preclinical nose to brain transport pharmacokinetics chitosan derivatives ophthalmology tight junctions sheep cationic functionalization GLP-1 pulmonary and liposome cytochrome P450 claudin P-glycoprotein in situ hydrogel mucoadhesiveness PTH 1-34 Aloe vera oral peptides |
| ISBN | 3-03921-849-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910372785603321 |
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Maher Sam
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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