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Anticancer Inhibitors
| Anticancer Inhibitors |
| Autore | Fantacuzzi Marialuigia |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (216 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
breast cancer
tamoxifen LY294002 synergism apoptosis cell cycle tea (Camellia sinensis) flowers BTFS A2780/CP70 ovarian cancer cells S phase cell cycle arrest nicotinamide phosphoribosyltransferase NAD+ biosynthesis inhibitor azacyclohexane anticancer drug drug design enthalpy effect NSCLC Cathepsin K cell proliferation cell migration cell invasion mTOR isatin-hydrazones cytotoxicity CDK2 inhibitor ATP competitive inhibitor ADME analysis receptor tyrosine kinases protein-protein interactions protein engineering directed evolution angiogenesis binding affinity agonistic activity saponins phytochemicals tea (Camellia sinensis) flower ovarian cancer autophagy ZMYND8 tumorigenesis epigenetic regulation pro-oncogenic effects tumor suppression tacrine-coumarin derivatives DNA topoisomerases I, II lung carcinoma cells A549 chemotherapy prodrug drug targeting overexpressed enzymes ADC ADEPT GDEPT LEAPT PROTAC cyclin-dependent kinase cancer resistance small molecule inhibitors PROTACs statins pancreatic cancer DNA microarray pitavastatin cerivastatin simvastatin fluvastatin atorvastatin pravastatin HMG-CoA reductase inhibitors |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069203321 |
Fantacuzzi Marialuigia
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cellular Oxidative Stress
| Cellular Oxidative Stress |
| Autore | Marino Angela |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (529 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
3-glutathionyl-4-hydroxynonanal
4-hydroxy-2-nonenal A2E acute pancreatitis adaptive immune response adipose-derived stem cells age-related macular degeneration (AMD) aging analgesic anion exchange anoikis antioxidant antioxidants apoptosis artemisinin derivatives astrocytoma cells autophagy AVD band 3 Band 3 protein bradykinin calcium ionophore A23187 cancer cardiovascular diseases cashew nuts cell homeostasis cellular redox state cigarette smoke extract circRNA cisplatin nephrotoxicity clinical CNS pathology co-ultramicronization coagulation d-Galactose diabetes diet dietary chemicals diseases epilepsy erythrocytes ferroptosis fish glucose exposure glycation HeLa hemichromes hemostasis hepatic steatosis immune system immunosenescence inflammation interleukin 1β legumes lipid dyshomeostasis liver lncRNA luteolin matrix metalloproteinase matrix metalloproteinases microparticles microvascular permeability miRNA mitochondrial function molecular hydrogen mucosal immunity n/a NAC NADPH oxidase nasal fibroblasts nasal immunity natural compounds ncRNA neurodegeneration neuroinflammation NF-κB nitric oxide donor nitrosative stress obesity oxidative stress palmitoylethanolamide palmitoylethanolamide (PEA) paracrine factors paw edema peroxide PGC-1α phytochemicals Plasmodium falciparum platelets polyphenols preeclampsia programmed cell death prooxidant pyroptosis reactive oxygen species reactive oxygen species (ROS) Retinitis pigmentosa RNA-Seq ROS RPE simvastatin SO42− SO42− uptake soy soy foods soybeans status epilepticus steroids Substance-P syk kinase inhibitors T cells tert-Bytyl hydroperoxide t-BOOH therapeutic strategies tissue inhibitor of metalloproteinases traumatic brain injury tRNA fragments Trolox vaccination vesiculation vitamin C |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557338703321 |
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Marino Angela
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Kidney Inflammation, Injury and Regeneration 2020
| Kidney Inflammation, Injury and Regeneration 2020 |
| Autore | Baer Patrick C |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (318 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
ACEI
acute kidney injury adaptive immunity anemia anemia of inflammation angiotensin II apoptosis autophagy B cells BAFF Bcl-XL biomarker chemokines chronic kidney disease cilastatin CKD coinhibition corticosteroids costimulation cyclophilin A cytochrome C diabetic nephropathy dieckol DJ-1 E. cava extracts endocan endotoxin epithelial-to-mesenchymal transition ERK ESA hyporesponsiveness ESM-1 extracellular matrix fibrosis focal segmental glomerulosclerosis FSGS glomerulonephritis Hippo pathway hypercholesterolemia hypoxia inducible factor-1-α IgAN inflammation innate immunity iron ischemia-reperfusion injury kidney fibrosis kidney transplant kidney transplantation lipocalin-2 macrophages membranous nephropathy minimal change diseases ML171 myofibroblast activation n/a ND-13 NF-κB pathway NOX1 oxidative stress podocytes preeclampsia progression protein binding affinity proteinuria reactive oxygen species renal disease renal fibrosis renal inflammation renal replacement therapy renal tubular epithelial cells simvastatin spontaneously hypertensive rats SPR survivin T cells tertiary lymphoid organs TLR trehalose tubular apoptosis tubular necrosis UUO VEGF verteporfin xanthine oxidase |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557364503321 |
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Baer Patrick C
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transmucosal Absorption Enhancers in the Drug Delivery Field
| Transmucosal Absorption Enhancers in the Drug Delivery Field |
| Autore | Maher Sam |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (406 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
absorption enhancement
absorption enhancer absorption enhancers absorption modifying excipients Aloe vera amino acid amphiphilic polymers and liposome antiepileptic drug antimicrobial peptide biocompatibility studies bioenhancer block copolymers brush border Caco-2 Caco-2 cells cationic functionalization cell-penetrating peptide cell-penetrating peptide (CPP) cervicovaginal tumors chitosan chitosan derivatives claudin clinical trial CNS disorders combined microsphere compound 48/80 confocal laser scanning microscopy cornea curcumin cyclodextrin cytochrome P450 drug absorption enhancer drug administration drug delivery efflux enterocyte epithelial permeability epithelial transport epithelium F-actin FITC-dextran formulation gel gemini surfactant GLP-1 hydrophobization imatinib in situ hydrogel in vivo studies insulin intestinal absorption intestinal delivery intestinal epithelial cells intestinal permeation enhancers KLAL man mast cell activator metabolism mucoadhesion mucoadhesiveness N-dodecyl-?-D-maltoside (DDM) nanocapsules nanocrystals nanomedicine nanoparticle nanoparticles nasal nasal delivery nasal formulation nasal permeability nasal vaccination nose to brain delivery nose to brain transport nose-to-brain ocular conditions ocular delivery ocular drug delivery ophthalmology oral delivery oral macromolecule delivery oral peptides osteoporosis P-glycoprotein penetration enhancer penetration enhancers permeability permeation enhancer permeation enhancers pharmacokinetic interaction pharmacokinetics PN159 polymeric micelles poorly absorbed drug preclinical PTH 1-34 pulmonary quaternization safety salcaprozate sodium sheep simulated intestinal fluid simvastatin small intestine sodium caprate sodium cholate (NaC) sugar-based surfactants teriparatide thermogel system tight junction tight junction modulator tight junctions transepithelial electrical resistance transferrin transmucosal drug delivery transmucosal permeation tryptophan vaccine adjuvant vaginal delivery whole leaf |
| ISBN | 3-03921-849-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910372785603321 |
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Maher Sam
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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