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Cellular Senescence in Health, Disease and Aging: Blessing or Curse?
| Cellular Senescence in Health, Disease and Aging: Blessing or Curse? |
| Autore | Riessland Markus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (112 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
γH2AX
Alzheimer's disease DNA damage mild cognitive impairment senescence secreted protein acidic and rich in cysteine regeneration homeostasis cellular senescence biology of aging neurodegeneration brain geroscience senolytics tauopathy cancer stress response post-mitotic neuronal senescence amyotrophic lateral sclerosis senescence-associated secretory phenotype (SASP) cell-cycle melanoma pancreatic adenocarcinoma tumor infiltration chemotherapy resistance prostate inflammation AIM2 inflammasome POP3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cellular Senescence in Health, Disease and Aging |
| Record Nr. | UNINA-9910557382703321 |
Riessland Markus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Curcumin in Health and Disease / Beatrice Bachmeier
| Curcumin in Health and Disease / Beatrice Bachmeier |
| Autore | Bachmeier Beatrice |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI, , 2019 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto non controllato |
minerals
cancer treatment chitosan neurodegeneration antioxidant activity senescence tumor proliferation nanoparticles antimicrobial agents oxidative metabolites drug discovery Akt/mTOR signaling micronutrients ulcerative colitis transmission electron microscopy metabolic reprogramming curcumin death receptor chaperone-mediated autophagy wound healing brain ischemia autophagy Alzheimer's disease genes transthyretin inflammatory bowel disease cellular pathway centrifugal partition chromatography nutrition amyloid Curcuma longa protein aggregation supportive care IL-17 senolytics complementary medicine macronutrients structure activity relationship gastroprotection Zingiberaceae anti-inflamation TLC bioautography microbiota glioblastoma multiforme amyloidosis SHMT2 antioxidants silica apoptosis reflux esophagitis gastric ulcer TLC-MS anti-cancer anticancer ImageJ anti-tumor delivery system wound Helicobacter pylori direct protein binding protein misfolding tumor growth diet Crohn's disease hydrostatic counter-current chromatography ageing renal cell cancer gastric cancer amino-acids STAT3 mechanism of action inflamm-aging mitophagy necrotizing enterocolitis cell cycling vitamins turmeric tuber cancer tau protein |
| ISBN |
9783039214501
3039214500 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367753703321 |
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Bachmeier Beatrice
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| Basel, Switzerland : , : MDPI, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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DNA Replication Stress / Robert M. Brosh
| DNA Replication Stress / Robert M. Brosh |
| Autore | Brosh Robert M |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI, , 2019 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto non controllato |
Werner Syndrome
A549 cells epigenetic neurodegeneration Genome integrity adaptation cellular senescence genome instability Werner Syndrome Protein lipofuscin cell cycle checkpoints exonuclease 1 template-switching energy metabolism mutation frequency DNA replication fork regression motor neuron disease Microsatellites Alzheimer's disease chromatin remodeler repair of DNA damage AP site analogue mutagens replication timing Thermococcus eurythermalis nucleolar stress gene expression mutations spectra origin firing Fanconi Anemia superfamily 2 ATPase DNA translocation DNA repair SSB signaling homologous recombination common fragile sites 8-chloro-adenosine replication genome stability mutagenicity fork reversal multiple sclerosis non-B DNA protein stability heterogeneity ubiquitin SenTraGorTM (GL13) replication restart EdU ?-arrestin NER aging SSB end resection oxidative stress ATR dormant origins R loops DNA damage response Difficult-to-Replicate Sequences DNA double-strand repair endonuclease IV ALS double strand break repair premature aging replication stress EXO1 POL? translesion synthesis strand displacements G2-arrest DNA replication pattern SSB repair genome integrity G protein-coupled receptor kinase interacting protein 2 (GIT2) MMR replicative stress senolytics spacer interactome ATR-Chk1 DDR pathway C9orf72 replication fork restart translesion DNA synthesis DNA damage mismatch repair DNA replication stress DNA helicase Polymerase kappa DNA fiber assay H1299 cells TLS APE2 ageing cell death chromosome TopBP1 barley clock proteins post-translational modification 8-oxoG S phase ataxia telangiectasia mutated (ATM) G protein-coupled receptor (GPCR) Polymerase eta cancer G protein-coupled receptor kinase (GRK) helicase genomic instability Parkinson's disease nucleotide excision repair SupF |
| ISBN |
9783039213900
3039213903 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367564903321 |
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Brosh Robert M
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| Basel, Switzerland : , : MDPI, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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mTOR in Human Diseases / Olivier Dormond
| mTOR in Human Diseases / Olivier Dormond |
| Autore | Dormond Olivier |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI, , 2019 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto non controllato |
primary cilia
neurodegeneration nutrient sensor PI3K transcriptomics phosphorylation metabolic reprogramming autophagy Alzheimer's disease rapalogs liver angiogenesis mTOR complex MBSCs advanced biliary tract cancers Medulloblastoma epithelial to mesenchymal transition AMPK p70S6K lipid metabolism thyroid cancer sodium iodide symporter (NIS)/SLC5A5 male fertility anesthesia illumina mTOR inhibitor miRNA Hutchinson-Gilford progeria syndrome (HGPS) eIFs Emery-Dreifuss muscular dystrophy (EDMD) glucose AKT oral cavity squamous cell carcinoma (OSCC) glucose and lipid metabolism cellular signaling aging tumor microenvironment rapamycin leukemia chloral hydrate rapalogues schizophrenia T-cell acute lymphoblastic leukemia senescence lamin A/C neurotoxicity neurodevelopment inhibitor methamphetamine pulmonary fibrosis mTOR mTOR inhibitors combination therapy proteolysis fluid shear stress tumour cachexia biomarkers synapse gluconeogenesis mTOR signal pathway Sertoli cells immunosenescence miRNome protein aggregation senolytics metabolism NGS mTORC2 mTORC1 metabolic diseases IonTorrent apoptosis dopamine receptor nocodazole microenvironment everolimus acute myeloid leukemia immunotherapy spermatogenesis bone remodeling signalling targeted therapy ageing therapy NVP-BEZ235 fructose physical activity laminopathies MC3T3-E1 cells cell signaling microRNA cancer lipolysis melatonin Parkinson's disease |
| ISBN |
9783039210619
3039210610 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684303321 |
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Dormond Olivier
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| Basel, Switzerland : , : MDPI, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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