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Advanced Therapy Medicinal Products for Eye Diseases: Goals and Challenges
| Advanced Therapy Medicinal Products for Eye Diseases: Goals and Challenges |
| Autore | Diebold Yolanda |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (207 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
3D bioprinting
advanced therapies advanced therapy medicinal product ATMP blindness carbodiimide cell replacement cell sources cell therapy CLET collagen conjunctiva conjunctival epithelial cells cornea corneal limbus decellularized tissue matrix decellularized xenograft double-crosslinking dry eye EDC/NHS electrospinning eye fiber gene therapy glutaraldehyde hydrogel keratoplasty lacrimal fluid limbal niche limbal stem cell LSCD marketing authorization mesenchymal stem cell transplantation mesenchymal stem cells MPC polymer MSCT mucin n/a ocular ocular mucosa ocular surface ophthalmology optic nerve diseases polycaprolactone recellularization regulatory retina retinal diseases scaffold small intestinal submucosa sodium borohydride sodium metabisulfite stem cells stratification tissue engineering tissue regeneration urinary bladder matrix |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Advanced Therapy Medicinal Products for Eye Diseases |
| Record Nr. | UNINA-9910557675503321 |
Diebold Yolanda
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Age-Related Macular Degeneration and Diabetic Retinopathy
| Age-Related Macular Degeneration and Diabetic Retinopathy |
| Autore | Westenskow Peter D |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (228 p.) |
| Soggetto topico |
Biology, life sciences
Research and information: general |
| Soggetto non controllato |
3D models
577-nm laser age-related macular degeneration AMD anti-vascular endothelial growth factor anti-VEGF anti-VEGF therapy AT1-receptor autoantibodies autofluorescence biomarker biomarkers blood-neural barriers C4 central area thickness choroidal neovascularization classification complement system diabetic macular edema diabetic macular oedema diabetic retinopathy diabetic retinopathy severity scale disease modeling edema ETDRS classification ethnicity factor I general practice genetic variants glucose variability glycemic gap HDL indicators inner blood-retinal barrier intravitreal aflibercept laser fixed parameters leakage index machine learning mass spectrometry metabolites microaneurysms microphysiological systems microRNA n/a neovascular age-related macular degeneration neovascularization neurovascular unit OCT optical coherence tomography organ-on-a-chip panretinal leakage index PAR1 personalized medicine phenotypes precision medicine progression quantitative biomarkers real-life retina retinal imaging retinal thickness retinopathy risk factors semi-quantitative multiplex profilin subthreshold micropulse laser tomography type 2 diabetes ultra-widefield fluorescein angiography variability VEGF-A VEGF-B VEGF-receptor 2 visual acuity visual prognosis vitronectin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576879403321 |
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Westenskow Peter D
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemical Biology of Sterols, Triterpenoids and Other Natural Products : : A Themed Issue in Honor of Professor W. David Nes on the Occasion of His 65th Birthday / / Wenxu Zhou, De-an Guo
| Chemical Biology of Sterols, Triterpenoids and Other Natural Products : : A Themed Issue in Honor of Professor W. David Nes on the Occasion of His 65th Birthday / / Wenxu Zhou, De-an Guo |
| Autore | Zhou Wenxu |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (256 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
high-fat high-carbohydrate diet
toxicity oxysterol squalene cyclase sterol content sterolomics Polystichum Smith-Lemli-Opitz syndrome antifungals alkaloid cycloartenol synthase degeneration phytosterol Rhizopus arrhizus fibroblasts pod-blast fern cholesterol cytotoxic activity N-methylpiperidine. reductive deamination genetic disease isoprenoid steroid atherosclerosis granatane antioxidant wound healing development enzyme-assisted derivatization maturity terpene keratinocytes C4-demethylation complex (C4DMC) ?-sitosterol mesocarp sterol biosynthesis mechanism-based inactivators Mucorales gas chromatography-mass spectrometry (GC-MS) Girard reagent ROS sterol pattern N-methylcadaverine ?-tocopherol electrospray ionization-mass spectrometry human African trypanosomiasis HUVECs lipidomics campesterol triterpene oxyphytosterol leishmania Chagas disease LOX-1 sterol C24-methyltransferase antifungal effectivity ergosterol biosynthesis hormone glucose homeostasis retina solanaceae cholestanoic acid algal sterols cell migration withanolides insulin resistance Zingiber officinale posaconazole synthesis pre-diabetes pharmacognosy sterol 4-methylsterol oleanolic acid antiparasitic drugs lupeol oilseed aurelianolides divalent metal co-factor ligation bile alcohol phytosterols azoles infectious disease gingerols UV-radiation oil bodies ZnO sterol 14?-demethylase stigmasterol |
| ISBN |
9783038974178
303897417X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346835903321 |
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Zhou Wenxu
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diagnosis, Treatment and Prevention of Age-Related Macular Degeneration
| Diagnosis, Treatment and Prevention of Age-Related Macular Degeneration |
| Autore | Kodjikian Laurent |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (246 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
aflibercept
aflibercept monotherapy age-related macular degeneration age-related macular degeneration (AMD) AMD angiogenesis anti-vascular endothelial growth factor anti-VEGF anti-VEGF treatment AREDS2-HOME study arterial hypertension bevacizumab brolucizumab cardiovascular risk factors cataract surgery choriocapillaris choroidal neovascularisation choroidal neovascularization clinical trials comparative therapies Delphi disease activity effectiveness emerging treatment epithelial tear exudation fellow eye food supplement ForeseeHome AMD Monitoring System® good baseline visual acuity hereditary retinal dystrophy identification intravitreal anti-vascular endothelial growth factor lifestyle long-term FU macula-off rhegmatogenous detachment macular neovascularization meta-analysis meta-regression meteorin n/a neovascular age-related macular degeneration neovascular age-related macular degeneration (nAMD) nutrients oct-angiography optical coherence tomography optical coherence tomography angiography polypoidal choroidal vasculopathy prevention pro re nata regimen quiescent macular neovascularization ranibizumab reading acuity real-world evidence retina retinal deep perifoveal capillary plexus risk Sorsby Sorsby's fundus dystrophy STARS® superficial perifoveal capillary plexus switch therapy therapeutic innovation treat and extend treat-and-extend treatment change treatment outcome treatment-naive Vascular Endothelial Growth Factor (VEGF) visual acuity |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566469403321 |
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Kodjikian Laurent
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Emerging Mechanisms in Neuronal Signaling: from Cell Biology to Pathogenesis
| Emerging Mechanisms in Neuronal Signaling: from Cell Biology to Pathogenesis |
| Autore | Eduardo Guido Mario |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (454 p.) |
| Soggetto topico |
Neurosciences
Science: general issues |
| Soggetto non controllato |
cell signaling
developmental disorders lipid signaling metabolism neurodegeneration oxidative stress retina transcription factors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Emerging Mechanisms in Neuronal Signaling |
| Record Nr. | UNINA-9910557394703321 |
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Eduardo Guido Mario
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Genetic Testing for Rare Diseases
| Genetic Testing for Rare Diseases |
| Autore | Millán José |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (144 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
ACTG1
Altaians ataxia bioinformatics child clinical genetics DFNA5 DFNB4 dystonia early onset ataxia familial hearing loss genetic counselling genetic diagnosis genetic testing growth hormone deficiency GSDME hearing loss HMG-CoA lyase deficiency HMGCL HMGLD imprinting disorder inborn errors of metabolism inherited metabolic diseases inherited retinal diseases insulin-like growth factor 1 lysosomal disorders mosaicism multiple diagnoses MYH9 n/a network analysis neurodevelopment neuromuscular disease next generation sequencing NGS non-syndromic hearing loss phenotype pituitary microadenoma Prader-Willi syndrome professional recognition rare diseases recombinant human growth hormone retina ring chromosomes Russia single-exon CNV SLC26A4 Southern Siberia syndrome Turner syndrome Tuvinians whole exome sequencing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566479203321 |
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Millán José
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mitochondrial Dysfunction in Aging and Diseases of Aging / Richard H. Haas
| Mitochondrial Dysfunction in Aging and Diseases of Aging / Richard H. Haas |
| Autore | Haas Richard H |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (270 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
age-related diseases
sphingolipids glaucoma ALS neurodegeneration mitochondrial dysfunction adaptive immunity senescence de-emergence innate immunity cell danger response mitochondrial transfer axonal transport cytokines mitochondrial age-related macular degeneration prevention heart failure purinergic signaling autophagy Alzheimer's disease diabetic retinopathy proteostasis 1 immunosenescence Miro1 ROS metabolism optic nerve polypharmacy eIF2? Parkin coenzyme Q10 neurodegenerative disease DNA damage skin exercise nucleotide metabolism pasteur effect stress response inflammation retina drug-induced mitochondrial toxicity neuroinflammation exosomes reactive oxygen species 25(OH)D cardiomyopathy crabtree effect insulin resistance cardiovascular disease ageing genetic mutations metabokines mitochondria multiple sclerosis aerobic healing cycle SOD1 mitophagy PINK1 type 2 diabetes integrated cell stress response morbidity and mortality ultraviolet photoageing cancer aging 25(OH)2D lysosome NAD+ Parkinson's disease |
| ISBN |
9783039213283
3039213288 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367756303321 |
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Haas Richard H
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Therapies for Inherited Retinal Diseases
| Molecular Therapies for Inherited Retinal Diseases |
| Autore | Collin Rob W.J |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (262 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
AAV
ABCA4 adeno-associated viral adeno-associated virus (AAV) allele-specific knockdown antisense oligonucleotides AON-mediated exon skipping apical polarity apoptosis ARPE-19 cells autophagy autosomal dominant bipolar cells CEP290 chaperones chaperonins choroideremia Cilia elongation clathrin-coated vesicles clinical trials clustered regularly interspaced short palindromic repeats (CRISPR) compound therapies cones crumbs complex cyclic GMP DNA therapies DNA-wrapped gold nanoparticles drug delivery systems dual AAV endosomal trafficking Enhanced S-Cone Syndrome (ESCS) fetal retina Flanders founder c.4723A > G56R gapmer antisense oligonucleotides gene augmentation gene therapy gold nanoparticles heat shock response homology-directed repair (HDR) induced pluripotent stem cell (iPSC) inherited retinal disease inherited retinal diseases iPSC-derived photoreceptor precursor cells IRD Leber congenital amaurosis Leber congenital amaurosis and allied retinal ciliopathies microRNA Müller glia n/a necrosis nonprofit NR2E3 PAR complex patient registry photoreceptors protein degradation protein folding protein trafficking putative dominant negative effect REP1 retina retinal degeneration retinal inherited disorders retinal organoids retinal pigment epithelium retinitis pigmentosa Retinitis Pigmentosa (RP) Retinitis Pigmentosa GTPase Regulator retinogenesis RNA therapies RNA therapy rods RPE65 splicing modulation spontaneous nonsense correction Stargardt disease T nonsense mutation therapy translational translational medicine treatment unfolded protein response Usher syndrome |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674051103321 |
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Collin Rob W.J
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neuronal Development and Degeneration
| Neuronal Development and Degeneration |
| Autore | Zhang Wenbo |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 online resource (161 p.) |
| Soggetto topico |
Neurosciences
Science: general issues |
| Soggetto non controllato |
brain
degeneration neurodegenerative disease neuronal development retina |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557207603321 |
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Zhang Wenbo
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutrition and Eye Health
| Nutrition and Eye Health |
| Autore | Downie Laura |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (242 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
advanced glycation end products
age-related macular degeneration AGREE II AMD angiogenesis anti-inflammatory anti-oxidant antioxidant supplements carotenoids cataract chyrsin clinical practice guidelines clinical survey CODS corneal chemical burn corneal neovascularization (CNV) crocetin crocin Crocus Sativus L. Cucurbita argyrosperma cyclooxigenase-2 (COX-2) diabetes diabetic retinopathy diet dietary antioxidants dietary assessment dietary habits drug discovery dry eye electroretinography endoplasmic reticulum endoplasmic reticulum stress estrogen-deficient rats eye disease fatty acid fish oil flavonoids food frequency questionnaire glaucoma gut microbiota gut-retina axis inflammation interleukin-1? (IL-1?) Lactobacillus paracasei KW3110 lens lenses light light damage lutein macrophage mesozeaxanthin (RS zeaxanthin) micronutrients microvascular lesions n/a neoangiogenesis nuclear factor-kappaB (NF-?B) nutrition nutritional supplements omega-3 omega-3 polyunsaturated fatty acids oxidative stress personalised medicine photoreceptor degeneration phytoconstituents polyphenols preclinical models reduced glutathione retina retinal pigment epithelium rosmarinic acid RR-zeaxanthin saffron saponins sinapic acid supplements systematic reviews vascular endothelial growth factor (VEGF) visual cycle |
| ISBN | 3-03921-991-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910372786403321 |
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Downie Laura
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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