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A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder
| A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder |
| Autore | Frye Richard E |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (416 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
acyl-carnitines
ADHD amygdala anxiety Array-Comparative Genomic Hybridization (Array-CGH) ASD associated risk autism autism spectrum disorder autism spectrum disorder (ASD) autism spectrum disorders autonomic disorder B12 biomarker brain brain development cerebral folate deficiency children chromosomal microarray analysis clinical decision support tool clinical utility cobalamin concomitant condition copy number variants cortisol COVID-19 cytokines digital biomarkers disorder Ehlers-Danlos syndrome energy metabolism epigenetics fatty acid oxidation fecal metabolites females fetal development Fisher Discriminant Analysis flavonoids folate receptor alpha folate receptor alpha autoantibodies folates folinic acid gastrointestinal symptoms genetic testing genomics glutathione heart rate variability hypermobility spectrum disorders immune dysfunction immunoglobulin G inflammation integrative intervention intravenous immunoglobulin leucovorin locked-in network syndrome logistic regression analysis luteolin mast cell activation syndrome mast cells medical claims metabolomics methylation methylcobalamin microbiome microglia minerals mitochondria model monoamine neurotransmitters n/a network connectivity neuromodulation neurostimulation neurotransmitter deficiency non-linear complex dynamics nutraceuticals OCD omics oxidative stress PANDAS parents patient stratification personalized treatment strategy polygenic risk scores precision medicine pregnancy prenatal environment proteomics quality of life redox metabolism resting-state functional magnetic resonance imaging resveratrol retrospective analysis SARS-CoV-2 single nucleotide polymorphisms sleep anxiety social dyads socio-motor parameters stochastic analysis stress survey systematic review Temple Grandin temporal lobe epilepsy time series analysis transcriptomics transdermal electrical neuromodulation vitamins wearables whole exome sequencing whole genome sequencing α-amylase |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595075503321 |
Frye Richard E
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Mucoadhesive Polymers and Formulations for Transmucosal Drug Delivery
| Advances in Mucoadhesive Polymers and Formulations for Transmucosal Drug Delivery |
| Autore | Khutoryanskiy Vitaliy |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (206 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
acrylated chitosan
alkyl lactate Alzheimer's disease biocompatibility buccal mucosa drug delivery Caco-2 cells Candida albicans Carbopol Carbopol® chitosan chitosan derivatives chitosan-catechol clobetasol clotrimazole controlled release cyclodextrins cytotoxicity detachment force drug delivery electrospinning Eudragit® E PO films furosemide gellan gum hydrogel hydroxypropyl cellulose in vitro permeability interpolyelectrolyte complex interpolymer complexes l-arginine liposphere maltodextrin mucoadhesion mucoadhesive mucoadhesive microspheres mucoadhesive polymer mucoadhesive polymers mucosal drug delivery mucosal membranes nanoparticles omeprazole oral lichen planus oral lyophilisates paediatric pectin pioglitazone PLGA-PEG pluronic f127 poly (vinylpyrrolidone) poly(2-ethyl-2-oxazoline) resuspendibility resveratrol retention rheology scanning electron microscopic images storage and loss moduli texture profile analysis thermogelling polymers thermoresponsive polymers thiolated chitosan thiolated hyaluronic acid transmucosal permeations trimethyl chitosan triple co-culture model wound healing xanthan gum |
| ISBN | 3-03928-753-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404086403321 |
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Khutoryanskiy Vitaliy
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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AMP-Activated Protein Kinase Signalling
| AMP-Activated Protein Kinase Signalling |
| Autore | Neumann Dietbert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 online resource (452 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
?-linker
?RIM 2-methoxyestradiol 3T3-L1 A769662 acetyl-CoA activation loop adaptive thermogenesis adenosine monophosphate-activated protein kinase adherent junctions adipocyte adipose tissue AICAR AID Akt AML AMP-activated protein kinase AMP-activated protein kinase (AMPK) AMPK AMPK kinase AS160 assisted reproduction techniques atrophy autophagy beiging CaMKK2 carrier catechol-O-methyltransferase CBS cellular energy sensing chromatin remodeling CML CMML co-expression CREB developmental origins of health and disease (DOHaD) dietary fatty acids differentiation DNA methylation endothelial cells endothelial function endothelial nitric-oxide synthase energy deficiency energy metabolism energy utilization epigenetics epithelial cells exercise fatty acid oxidation fiber-type food intake gestational diabetes mellitus glucose uptake glycogen glycogen storage disease HDAC4/5 HDACs heat shock protein hepatocyte hindlimb suspension histone modification host defense hypertension hypertrophy hypothalamus IL-1? Immediate early genes indirect calorimetry infection insulin signalling ionomycin KATs kidney disease lipid metabolism liver LKB1 macrophages MDCK MDS mechanical unloading medulloblastoma membrane membranes metabolic disease metabolic-inflammation metabolism microarrays mitochondria monocytes motility motor endplate remodeling mTOR mycobacteria MyHC I(?) n/a NAD+ nectin-afadin NLRP3 nutrient-sensing signals nutrigenomics nutrition oxidative stress p70S6K par complex peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) phenylephrine phosphorylation PKA preeclampsia pregnancy proteasome protein acetylation protein kinase B protein synthesis pump regrowth renin-angiotensin system resveratrol signaling sirtuin 1 (SIRT1) skeletal muscle soleus muscle soluble Adenylyl cyclase sonic hedgehog spermatozoa steatosis stress synaptic activation TAK1 TBC1D4 tight junctions transcription transporter ULK vasoconstriction vasodilation ZO-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346858503321 |
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Neumann Dietbert
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antitumor and Anti-HIV Agents from Natural Products
| Antitumor and Anti-HIV Agents from Natural Products |
| Autore | Nakagawa-Goto Kyoko |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (338 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
acute toxicity
allyl isothiocyanate Angelica dahurica anti-HIV antiangiogenic antioxidants antiproliferation antiproliferative activity antiretroviral agents antitumor activity apoptosis Artemisia absinthium L. aspidosperma-type benzyl isothiocyanate bladder cancer Bousigonia mekongensis BRAF inhibitor breast cancer butanolides caffeic acid cancer cancer multidrug resistance cancer stem cell Carpesium divaricatum cell cycle cell cycle arrest cervical cancer chemistry chemoprevention cisplatin coumarins curcumin analog cytotoxicity delcosine delpheline diterpenoid alkaloids DOTA drug development drug-drug interaction epithelial-to-mesenchymal transition essential oil flavonoids G2/M phase cell cycle arrest HaCaT cells HEF cell line hepatocellular carcinoma hepatoma cells Hernandia nymphaeifolia human tumor cell lines human tumor cells inflammation Ivalin kobusine lignan glycosides lipojesaconitine marine metabolites matrix metalloproteinase medicine melanoma melanoma and breast cancer cell line Mentha aquatica var. Kenting Water Mint metastasis mitochondria-mediated apoptosis monoterpenoid indole alkaloids natural agents natural phaeosphaeride A natural products NF-κB oral squamous cell carcinoma cells oxidative stress oxypeucedanin P-glycoprotein p53 phenethyl isothiocyanate phenolic acid pseudokobusine pterostilbene quercetin reactive oxygen species resveratrol SK-Hep-1 sulforaphane tamoxifen taxol total phenolic content transforming growth factor-β1 triterpenoids tubulin inhibitor tumor suppression two-stage skin carcinogenesis ursolic acid β-lapachone |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557504803321 |
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Nakagawa-Goto Kyoko
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Benefits of Resveratrol Supplementation / María P. Portillo, Alfredo Fernandez-Quintela
| Benefits of Resveratrol Supplementation / María P. Portillo, Alfredo Fernandez-Quintela |
| Autore | Portillo María P |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
polyphenols
?-viniferin leptin resistance p53 kidney energy restriction grape powder extract cytokines phosphorylation obesity energy metabolism metabolic pathways endothelial function polyol pathway antioxidant caloric restriction rat adipose tissue microparticles pathways angiotensin converting enzyme 2 resistance esRAGE interleukins metabolic syndrome dissolution rate thermogenesis streptozotocin bioavailability solubility metabolism renin-angiotensin system microbiota Sirt-1 magnesium dihydroxide hypertrophy metabolic diseases physiological adaption red wine extract lens distribution MTA1 sirtuin inflammation cardiac function rats cisplatin resveratrol mitochondria breast cancer ischemia-reperfusion cardiovascular metabolites gut microbiota prostate cancer performance type 2 diabetes cafeteria diet high-fat high-sucrose diet resistance exercise aging diabetes oxidative stress |
| ISBN |
9783039212767
3039212761 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346854603321 |
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Portillo María P
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Benefits of the Mediterranean Diet-Wine Association: Role of Components
| Benefits of the Mediterranean Diet-Wine Association: Role of Components |
| Autore | Silva Paula |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (208 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
(+)-catechin
(+)-taxifolin 7-ketocholesterol acetaldehyde alcohol AMD apigenin apoptosis ARPE-19 butyric acid cancer carcinogenesis cardiovascular disease cerebellum clinical trials Crohn's disease degenerative diseases dementia diet docosahexaenoic acid eicosapentaenoic acid ethanol flavonoids inflammation inflammatory bowel disease malvidin 3-O-glucoside Mediterranean diet metabolites n/a N2a cells neurodegeneration neuronal death neuroprotection novel delivery system ocular diseases oleic acid olive oil oocyte quality oral cavity cancer oxidative stress peonidin 3-O-glucoside pharmacology phytochemicals polydatin polyphenols postovulatory aging prevent fat accumulation quercetin quercetin 3-O-glucoside reactive oxygen species red wine extract resveratrol resveratrol butyrate ester retinal cells Steglich esterification therapeutic targets tyrosol ulcerative colitis wine wine intake α-linolenic acid |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Benefits of the Mediterranean Diet—Wine Association
Benefits of the Mediterranean DietâWine Association |
| Record Nr. | UNINA-9910576886703321 |
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Silva Paula
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bioactive Phytochemicals in Health and Disease
| Bioactive Phytochemicals in Health and Disease |
| Autore | Iriti Marcello |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (264 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
Acorus calamus
autophagy B16F10 cells cancer cardiovascular disease chlorogenic acid chloroquine citric acid clinical trial cognitive impairment coronavirus COVID-19 curcumin diet ethnomedicinal flavonoids food supplements HCoV-OC43 hormesis infection kaempferol kurarinone LC3 liposome liposomes malic acid matrix metalloproteinase melanoma metabolic application micronuclei molecular signals MRC-5 cell n/a nanocarriers nanocurcumin nanoformulation nanomedicine naringin nervous system neurological neurological disorders neuroprotective orientin p62/SQSTM1 protein pharmacological action pharmacological potential phytochemistry phytoestrogens PNT2 quercetin quinic acid radiation effects radioprotectors remdesivir resveratrol RNA-dependent RNA polymerase rosmarinic acid rutin SARS-CoV-2 skin rejuvenation spike glycoproteins sulforaphane toxicity transforming growth factor Ulmus parvifolia vitexin wound healing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557389003321 |
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Iriti Marcello
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biochemical Biomarkers and Neurodegenerative Diseases
| Biochemical Biomarkers and Neurodegenerative Diseases |
| Autore | Ciaccio Marcello |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (156 p.) |
| Soggetto topico |
Medicine and Nursing
Neurosciences |
| Soggetto non controllato |
25(OH)D levels
AD ALS Alzheimer's disease Alzheimer's Disease AMPK amyloid beta amyloid precursor protein amyotrophic lateral sclerosis Arylsulfatase A astrocytes beta amyloid biomarker biomarkers cerebral ischemia essential tremor focused ultrasound FOXP3 Fyn tyrosine kinase GATA3 Gaucher's disease genetic GLUT3 GSK3β GWAS high-intensity focused ultrasound ablation image quality inherited neuromuscular disorders iron lysosomes magnetic resonance imaging MCAO MR-guided focused ultrasound multiple sclerosis n/a nervous system neurodegenerative disease neurodegenerative diseases neurodegenerative nisease neuroinflammation neuromelanin nigrosome-1 Parkinson's disease parkinsonian disorders PD polymorphisms prognostic biomarker radiomics rare diseases resveratrol SARS-CoV-2 stereotaxic techniques Tyr682 residue vitamin D Vitamin D Vitamin D deficiency YENPTY motif |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557361103321 |
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Ciaccio Marcello
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological Activities of Plant Food Components: Implications in Human Health
| Biological Activities of Plant Food Components: Implications in Human Health |
| Autore | Gentile Carla |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (168 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
ABTS
African food spices amylase angiotensin-converting enzyme anti-obesity antibiofilm anticancer anticholinesterase antidiabetes antimicrobial antioxidant antioxidant activity antioxidant capacity antioxidants antityrosinase antiurease Bangladesh barley bioactivities bioavailability buckwheat CAA carotenoids copper cytotoxicity deep-fried product DPPH durum wheat bread essential fatty acids flavonoids FRAP GC-MS (gas chromatography mass spectrometry) glucosidase hydrolysable tannins Job's tears lipase mass spectrometry mineral content molecular mechanisms n/a necroptosis oil deterioration omega-6/omega-3 ratio oxidative stress plant extract polyphenol polyphenols Portulaca oleracea L. proanthocyanidins Punica granatum renin resveratrol secondary metabolite sensory analysis swarming inhibition swimming inhibition tempura Ultra High Performance Liquid Chromatography-Orbitrap-Mass Spectrometry vegetables viability violacein inhibition yeast γH2AX |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Biological Activities of Plant Food Components |
| Record Nr. | UNINA-9910557529403321 |
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Gentile Carla
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cyanobacteria and Cyanotoxins: New Advances and Future Challenges
| Cyanobacteria and Cyanotoxins: New Advances and Future Challenges |
| Autore | Cameán Fernández Ana María |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (246 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
[d-Leu1]Microcystin-LR
16S rRNA gene 16S rRNA gene sequencing akinetes anatoxin-a Aphanizomenon flos-aquae apoptosis arctic Artemia salina astaxanthin bacterial community benthic mats bioassays blue-green algae supplements cyanobacteria cyanobacterial thresholds cyanotoxins cylindrospermopsin Cylindrospermopsin cytotoxicity detection drinking water drinking water treatment plant ELISA energy budget exposure genotoxicity harmful algal blooms hemolytic essay Histopathological evaluation in vitro lettuce Lithobates catesbeianus marine cyanobacteria marine natural compounds marine sponges method validation microbial metabolisms microcystin microcystin-LR Microcystin-LR microcystin-LR (MC-LR) microcystins mixture monoclonal antibody mutagenicity Nostocales nutrient enrichment oxidative stress Paracentrotus lividus PCR phylogenetic analyses Procambarus clarkii PSP toxins reproductive toxicity reservoir resveratrol saxitoxin secondary metabolites shotgun metagenomic sequencing sirtuin 1 (SIRT1) tadpoles taste-and-odor compounds time-resolved fluoroimmunoassay UPLC-MS/MS water source Yangtze estuary |
| ISBN | 3-03921-839-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cyanobacteria and Cyanotoxins |
| Record Nr. | UNINA-9910404089003321 |
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Cameán Fernández Ana María
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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