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Actinomycetes : The Antibiotics Producers
| Actinomycetes : The Antibiotics Producers |
| Autore | Stegmann Evi |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (362 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Streptomyces
biogeography comparative genomics diversification secondary metabolite biosynthetic gene clusters SMGC natural products streptomyces rishirilide biosynthesis polyketides polynucleotide phosphorylase ribonuclease regulation promoter RNA decay polyadenylation (p)ppGpp antibiotic antibiotics geomicrobiology Illumina sequencing microbiome diversity Actinobacteria Cave microbiology secondary metabolite rare Actinobacteria Amycolatopsis unculturability siderophore glycopeptide antibiotics dbv cluster regulatory genes StrR LAL LuxR solo dalbavancin A40926 Streptomyces lividans secretion pathways secretory proteins signal peptides actinomycetes teicoplanin van resistance genes Streptomyces tsukubaensis tacrolimus FK506 omics screening secondary metabolism differentiation elicitors morphology liquid cultures metagenomics rare actinomycetes dereplication metabolomics genome mining secondary metabolites novel compounds physicochemical screening physical and chemical properties structural diversity biological activity Actinoallomurus antibiotics polyethers lysolipin minimal PKS II cyclases benz[a]naphthacene quinone tridecaketide aromatic polyketide pentacyclic angular polyphenol extended polyketide chain actinobacteria β-lactamase resistance β-lactamase inhibitor polyketide synthases acyltransferases engineering new bioactive compounds symbiosis drug discovery chemical ecology culture-based approaches strain specialized metabolites biosynthetic gene cluster |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Actinomycetes |
| Record Nr. | UNINA-9910557114803321 |
Stegmann Evi
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (528 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
melanoma
invasion WNT5A MARCKS phosphorylation MANS peptide nanoparticles cell therapy tumor microenvironment sex/gender sex-hormones immunity microRNAs immunotherapy BRAF-mutant melanoma BRAF inhibitor mechanism of action targeted therapy tumour microenvironment plasmacytoid dendritic cells lactate dehydrogenase TLR interferon CXCL10 TPC2 HIPPO SOCE metastasis essential oils angiogenesis apoptosis uveal melanoma (UM) metastatic uveal melanoma (mUM) prognostication adjuvant therapy metastatic therapy metastatic dormancy liver-directed-therapies targeted-therapy combined therapy protein tyrosine phosphatase PTPs inhibitors melanoma immune infiltrate BRAF inhibitors microenvironment resistance therapy therapeutic resistance exosomes extracellular vesicles diagnosis prognosis ctDNA liquid biopsy prediction patient stratification BRAF arthralgia rheumatoid arthritis carbonic anhydrase hedgehog cyclopamine small molecules acetazolamide motility metalloproteinases FAK cancer mucosal melanoma nivolumab pembrolizumab ipilimumab radiotherapy cholinergic system acetylcholine muscarinic receptors nicotinic receptors melanoma metastasis ShcD adaptor protein amoeboid motility Rac1 DOCK4 melanoma PDX target therapy cancer stem cells slow cycling phenotype drug resistance OXPHOS lipid metabolism cancer associated fibroblast melanomagenesis biomarkers checkpoint inhibitor PD-1 melanoma markers cytokines machine learning Support Vector Machine principal component analysis BCL2L10 STAT3 cytotoxicity survival ABT-737 Bcl-2 family ML258 HuR MITF metastases siRNA |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
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Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
| Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing |
| Autore | Kim Jong Heon |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
nanoparticles
fungi drug delivery systems marine biological synthesis myconanotechnology canesten clotrimazole vulvovaginal vaginitis mycosis candidosis yeast infection candida candida albicans vaginal health anticandidal activity indazole pyrazole 3-phenyl-1H-indazole drug design acetylsalicylic acid (ASA, aspirin) capsule CAP64 Cryptococcus membrane potential (ΔΨM) photodynamic treatment photosensitiser ultrastructure drug repurposing antifungals repositioning yeasts emerging fungi multidrug resistance therapeutic alternatives new targets Candida auris Aspergillus spp antifungal beta-glucan polycations Galleria mellonella model retinoids Candida spp onychomycosis Malassezia spp dermatophytes microbiology mycology all-trans retinoic acid Acanthamoeba free-living ameba Acanthamoeba keratitis isavuconazonium sulfate cyst drug drug discovery drug targets invasive aspergillosis treatment invasive fungal infections fission yeast cell wall β(1,3)-D-glucan synthase antifungal drugs echinocandin drugs echinocandin resistance Fks resistance hot spots cytokinesis septation cell separation cell integrity cell lysis sporotrichosis Felis catus quinones hydrazones zoonoses host-directed drug therapy azoles polyenes echinocandins viral infections azole synergy resistance Candida natural products |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Advances in Antifungal Development |
| Record Nr. | UNINA-9910585935503321 |
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Kim Jong Heon
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Biological Understanding of Tumor Radiation Resistance
| Advances in Biological Understanding of Tumor Radiation Resistance |
| Autore | Ida Skvortsova Ira |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (235 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
Cancer stem cells
Radiation Oncology resistance tumor insensitivity radiation tumor response |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557212703321 |
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Ida Skvortsova Ira
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in Parasitic Weeds Research
| Advances in Parasitic Weeds Research |
| Autore | Hanan Eizenberg |
| Pubbl/distr/stampa | Frontiers Media SA, 2018 |
| Descrizione fisica | 1 electronic resource (334 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
parasitic weeds
striga weed management broomrape resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346759003321 |
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Hanan Eizenberg
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| Frontiers Media SA, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Alcatraz [[electronic resource] ] : the gangster years / / David A. Ward ; with Gene Kassebaum
| Alcatraz [[electronic resource] ] : the gangster years / / David A. Ward ; with Gene Kassebaum |
| Autore | Ward David A |
| Pubbl/distr/stampa | Berkeley, : University of California Press, c2009 |
| Descrizione fisica | 1 online resource (578 p.) |
| Disciplina | 365/.979461 |
| Altri autori (Persone) | KassebaumGene G |
| Soggetto topico | Prisons - California - Alcatraz Island - History |
| Soggetto non controllato |
20th century american crime
20th century american history al capone alcatraz alvin karpis american government convicts crime dock barker escape attempts fbi federal bureau of prisons federal government federal parole records gangsters george kelly infamous criminals inmates machine gun kelly outlaws penal policy penitentiary prison administrators prison guards prison public enemy resistance security supermax prison the rock worst of the worst |
| ISBN |
1-282-77248-1
9786612772481 0-520-94298-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Frontmatter -- CONTENTS -- PREFACE -- ACKNOWLEDGMENTS -- Introduction: Reconstructing the Life of a Prison -- 1. The Federal Government's War on "Public Enemies" -- 2. A New Form of Imprisonment -- 3. Selecting the "Worst of the Worst" -- 4. The Program -- 5. Organized Resistance: A Regime Tested -- 6. Finding a Hole in the Rock: The First Escape Attempts -- 7. Alcatraz on Trial -- 8. The War Years -- 9. The Battle of Alcatraz -- 10. Resistance and Adaptation -- 11. Outlaws among Outlaws -- 12. Celebrity Prisoners -- 13. Return to the Free World -- 14. Lessons from Alcatraz for Supermax Prisons -- EPILOGUE -- NOTES -- BIBLIOGRAPHIC COMMENTARY -- ABOUT THE AUTHORS -- INDEX |
| Record Nr. | UNINA-9910785270603321 |
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Ward David A
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| Berkeley, : University of California Press, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anticancer Inhibitors
| Anticancer Inhibitors |
| Autore | Fantacuzzi Marialuigia |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (216 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
breast cancer
tamoxifen LY294002 synergism apoptosis cell cycle tea (Camellia sinensis) flowers BTFS A2780/CP70 ovarian cancer cells S phase cell cycle arrest nicotinamide phosphoribosyltransferase NAD+ biosynthesis inhibitor azacyclohexane anticancer drug drug design enthalpy effect NSCLC Cathepsin K cell proliferation cell migration cell invasion mTOR isatin-hydrazones cytotoxicity CDK2 inhibitor ATP competitive inhibitor ADME analysis receptor tyrosine kinases protein-protein interactions protein engineering directed evolution angiogenesis binding affinity agonistic activity saponins phytochemicals tea (Camellia sinensis) flower ovarian cancer autophagy ZMYND8 tumorigenesis epigenetic regulation pro-oncogenic effects tumor suppression tacrine-coumarin derivatives DNA topoisomerases I, II lung carcinoma cells A549 chemotherapy prodrug drug targeting overexpressed enzymes ADC ADEPT GDEPT LEAPT PROTAC cyclin-dependent kinase cancer resistance small molecule inhibitors PROTACs statins pancreatic cancer DNA microarray pitavastatin cerivastatin simvastatin fluvastatin atorvastatin pravastatin HMG-CoA reductase inhibitors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595069203321 |
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Fantacuzzi Marialuigia
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antiviral Agents
| Antiviral Agents |
| Autore | Adamson Catherine |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (386 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Zika virus
nucleoside analogues antiviral agents NS5 prodrugs ProTides neural stem cells RNA-dependent RNA polymerase cytomegalovirus latent infection TALEN Surveyor nuclease mutation detection assay ie-1 gene quantitative real-time PCR Epstein-Barr virus herpes viruses lytic gene expression Burkitt lymphoma cells clozapine antipsychotic drug antiviral drug enteroviruses coxsackievirus B4 persistent infection fluoxetine resistance mutations herpes B virus macacine herpesvirus-1 genistein flavonoids acyclovir ganciclovir Plantago asiatica Clerodendrum trichotomum RSV therapeutic effects acteoside human antimicrobial peptides antiviral strategies defensins cathelicidins hepcidins transferrins influenza A virus brevilin A antiviral sesquiterpene lactone replication PRRSV polyethylenimine PEI virion internalization endocytosis HIV pediatrics Ethiopia pre-treatment drug resistance combination antiretroviral therapy (cART) dried plasma spots dried blood spots sphingolipids glycosphingolipids viruses lipid biosynthesis flavivirus Japanese encephalitis virus furin inhibitor precursor membrane protein measles virus central nervous system tropism treatments porcine reproductive and respiratory syndrome virus ginsenoside Rg1 antiviral activity pro-inflammatory factor NF-κB signaling pathway acute/latent infection congenital infection antiviral agent therapeutic strategies nucleic acid-based therapeutic approach HCMV vaccine adoptive cell therapy Rev response element chemical footprinting SHAPE drug discovery branched peptides herpesvirus immediate-early IE1 IE2 ribozyme RNA interference CRISPR/Cas small molecule orthohantavirus phenyl-benzotriazoles C-FRA Porcine circovirus type 2 epigallocatechin gallate heparan sulfate antiviral effect virus attachment microvirin lectin human immunodeficiency virus hepatitis C virus antiviral inhibitor non-immunogenic viral entry protein drugs LUMS1 oleanane-type derivatives influenza A virus (IAV) virus entry inhibitors hemagglutinin (HA) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557448703321 |
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Adamson Catherine
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Apocalypse in Rome : Cola di Rienzo and the politics of the new age / / Ronald G. Musto
| Apocalypse in Rome : Cola di Rienzo and the politics of the new age / / Ronald G. Musto |
| Autore | Musto Ronald G |
| Pubbl/distr/stampa | Berkeley, : University of California Press, 2003 |
| Descrizione fisica | 1 online resource (xx, 436 pages, 20 unnumbered pages of plates) : illustrations, maps |
| Disciplina |
945/.63205/092
B |
| Soggetto topico | Revolutionaries - Italy - Rome |
| Soggetto non controllato |
assassination
barons biography buono stato capitoline catholic church central italy christianity cola di rienzo correspondence coup cultural history diplomacy documentary history emperor fall of rome fugitive government italian history italy medieval nonfiction orator papacy petrarch political exile political history political prisoner politicians politics pope clement vi pope rebellion religion resistance revolution roman empire roman history roman leaders romans rome tiber |
| ISBN |
1-283-27706-9
9786613277060 0-520-92872-5 1-59734-471-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Front matter -- Contents -- List of Illustrations -- List of Tables -- Preface and Acknowledgments -- List of Abbreviations -- Introduction: Cola di Rienzo -- 1. Birth, Youth, and Society -- 2. Education, Profession, and Family -- 3. Reviving Antiquity -- 4. The Popes at Avignon -- 5. Cola and the Barons -- 6. Preparing for the Apocalypse -- 7. Pentecost -- 8. The Buono Stato -- 9. Cola and the World -- 10. War with the Barons -- 11. Abdication and Exile -- 12. Last World Emperor and Angel Pope -- 13. Apocalypse in Rome -- Notes -- Bibliography -- Index |
| Record Nr. | UNINA-9910780446903321 |
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Musto Ronald G
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| Berkeley, : University of California Press, 2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Asthma : Current Perspectives on Phenotypes, Endotypes, and Treatable Traits
| Asthma : Current Perspectives on Phenotypes, Endotypes, and Treatable Traits |
| Autore | Rovina Nikoletta |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (280 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
asthma
lactic acidosis hyperchloremic acidosis hypocapnia hypercapnia wheezing bronchial biopsies symptom persistence clinical remission eosinophil adhesion viability proliferation airway smooth muscle cell pulmonary fibroblast phenotype acute severe asthma exacerbation near fatal asthma severe asthma inflammation interleukin-5 (IL-5) anti-IL-5 interleukin-4 airway remodeling matrix metalloproteinases-9 tissue inhibitor of metalloproteinase-1 alveolar macrophages lung function bronchodilation resistance obstruction reproducible spirometry obstructive sleep apnea bronchial asthma alternative overlap syndrome exacerbation reactive oxygen species PBMC mitochondrial function innate immunity immune regulation NLRP3 IL-1β allergic airway inflammation microbiome pathogenesis immune responses PreDicta preschool FeNO asthma-specific quality of life chronic rhinitis disease-specific quality of life health-related quality of Life (HRQLQ) children longitudinal study |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Asthma |
| Record Nr. | UNINA-9910557749803321 |
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Rovina Nikoletta
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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