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DNA Replication Stress / Robert M. Brosh
| DNA Replication Stress / Robert M. Brosh |
| Autore | Brosh Robert M |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Biology, life sciences |
| Soggetto non controllato |
Werner Syndrome
A549 cells epigenetic neurodegeneration Genome integrity adaptation cellular senescence genome instability Werner Syndrome Protein lipofuscin cell cycle checkpoints exonuclease 1 template-switching energy metabolism mutation frequency DNA replication fork regression motor neuron disease Microsatellites Alzheimer's disease chromatin remodeler repair of DNA damage AP site analogue mutagens replication timing Thermococcus eurythermalis nucleolar stress gene expression mutations spectra origin firing Fanconi Anemia superfamily 2 ATPase DNA translocation DNA repair SSB signaling homologous recombination common fragile sites 8-chloro-adenosine replication genome stability mutagenicity fork reversal multiple sclerosis non-B DNA protein stability heterogeneity ubiquitin SenTraGorTM (GL13) replication restart EdU ?-arrestin NER aging SSB end resection oxidative stress ATR dormant origins R loops DNA damage response Difficult-to-Replicate Sequences DNA double-strand repair endonuclease IV ALS double strand break repair premature aging replication stress EXO1 POL? translesion synthesis strand displacements G2-arrest DNA replication pattern SSB repair genome integrity G protein-coupled receptor kinase interacting protein 2 (GIT2) MMR replicative stress senolytics spacer interactome ATR-Chk1 DDR pathway C9orf72 replication fork restart translesion DNA synthesis DNA damage mismatch repair DNA replication stress DNA helicase Polymerase kappa DNA fiber assay H1299 cells TLS APE2 ageing cell death chromosome TopBP1 barley clock proteins post-translational modification 8-oxoG S phase ataxia telangiectasia mutated (ATM) G protein-coupled receptor (GPCR) Polymerase eta cancer G protein-coupled receptor kinase (GRK) helicase genomic instability Parkinson's disease nucleotide excision repair SupF |
| ISBN |
9783039213900
3039213903 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367564903321 |
Brosh Robert M
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Killing Cancer : Discovery and Selection of New Target Molecules
| Killing Cancer : Discovery and Selection of New Target Molecules |
| Autore | Kallunki Tuula |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (302 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
3D growth
ABCG2 AF1Q anoikis ATP-binding cassette transporter ATP6V0a3 ATR pathway autophagy BRCA1 BRCA2 breast cancer resistance protein (BCRP) breast cancer stem cells C2 domain cancer cancer metabolism cancer therapy CD domain chondroitin sulfate colorectal cancer dexamethasone disulfiram DNA damage drug efflux pumps dysferlin EMT epithelial-mesenchymal transition ERK1 ERK2 esophageal cancer ferlin glucocorticoids IL-8 immunotherapy inflammation invasion kinase inhibitors lysosome lysosome-mediated invasion mammosphere MAPK kinase matrix degradation metabolism microgravity microsatellite instability migration MLLT11 mTOR in immunotherapy mTOR inhibitors mTOR signaling mTORC1 mTORC2 multidrug resistance in cancer myoferlin MZF1 n/a NF-κB NPL4 nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-κB) nutrient metabolism oncofetal chondroitin sulfate otoferlin PAK4 PDAC pediatric cancer pH-regulation phosphorylation plasma membrane prognosis proliferation pyrazolo-pyrimidine derivative rapalogs replication stress Rolled SCH772984 SCO-201 sevenmaker solid tumors space environment STAT sulconazole SUMOylation target targeted cancer therapy TCIRG1 thyroid cancer transcription factor VAR2 VRT-11E WNT zinc finger |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Killing Cancer |
| Record Nr. | UNINA-9910557648103321 |
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Kallunki Tuula
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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MicroRNA and Cancer
| MicroRNA and Cancer |
| Autore | Tucci Paola |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (298 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
2'-O-methylation
adipokines B-CLL bioinformatics analysis biomarker blood biomarker brain tumour breast cancer Breast cancer cancer stem cell cancer stem cells ccRCC circulating biomarkers circulating microRNA colon cancer Cyclooxygenase-2 (COX-2) deformability diagnosis endometrial cancer estrogens exosome head and neck squamous cell carcinoma hepatocellular carcinoma hyperinsulinemia Hypoxia inducible factor 1-alpha (HIF-1α) immune checkpoint inhibitors immunotherapy insulin insulin resistance insulin signaling insulin-like growth factors malignant melanoma medulloblastoma meta-analysis metastasis metastatic melanoma methylation microRNA MicroRNA (miRNA) microRNAs Migration miR-584-5p miR526b miR655 miRNA miRNA-transcription factor network miRNAs n/a non-small cell lung cancer normal B-cell development ovarian cancer Oxidative stress PARP PI3K/Akt plasma prediction prognosis prognostic factor progression Prostaglandin E2 receptor 4 (EP4) pseudouridylation RCC regulation renal cancer replication stress serum LDH smoking snoRNA stem cells stemness subgroups survival targeted therapy therapy YKT6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213503321 |
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Tucci Paola
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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