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AMP-Activated Protein Kinase Signalling
| AMP-Activated Protein Kinase Signalling |
| Autore | Neumann Dietbert |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (452 p.) |
| Soggetto non controllato |
HDACs
transcription epigenetics spermatozoa par complex A769662 MDCK skeletal muscle AID phosphorylation energy metabolism monocytes autophagy CML liver hindlimb suspension pregnancy preeclampsia gestational diabetes mellitus CaMKK2 assisted reproduction techniques nutrient-sensing signals sonic hedgehog protein acetylation glycogen storage disease AMPK adenosine monophosphate-activated protein kinase AICAR indirect calorimetry IL-1? MyHC I(?) HDAC4/5 endothelial cells infection hepatocyte p70S6K lipid metabolism host defense exercise kidney disease heat shock protein ?RIM mycobacteria activation loop developmental origins of health and disease (DOHaD) CREB TAK1 metabolic-inflammation phenylephrine AMP-activated protein kinase (AMPK) KATs 2-methoxyestradiol DNA methylation NLRP3 pump ?-linker steatosis AMPK kinase stress endothelial nitric-oxide synthase vasodilation adherent junctions epithelial cells glycogen Akt synaptic activation cellular energy sensing glucose uptake transporter co-expression atrophy nutrigenomics motility vasoconstriction fatty acid oxidation oxidative stress AS160 membrane histone modification sirtuin 1 (SIRT1) chromatin remodeling insulin signalling dietary fatty acids ULK CMML adaptive thermogenesis mTOR MDS mechanical unloading AML endothelial function medulloblastoma PKA adipose tissue NAD+ membranes nutrition ZO-1 TBC1D4 adipocyte soluble Adenylyl cyclase metabolism renin-angiotensin system energy utilization proteasome differentiation signaling peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) hypertrophy AMP-activated protein kinase metabolic disease LKB1 soleus muscle macrophages Immediate early genes CBS benign motor endplate remodeling ionomycin nectin-afadin tight junctions resveratrol protein kinase B regrowth mitochondria protein synthesis energy deficiency catechol-O-methyltransferase fiber-type microarrays carrier acetyl-CoA hypertension 3T3-L1 hypothalamus food intake |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346858503321 |
Neumann Dietbert
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Benefits of Resveratrol Supplementation
| Benefits of Resveratrol Supplementation |
| Autore | Fernandez-Quintela Alfredo |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto non controllato |
polyphenols
?-viniferin leptin resistance p53 kidney energy restriction grape powder extract cytokines phosphorylation obesity energy metabolism metabolic pathways endothelial function polyol pathway antioxidant caloric restriction rat adipose tissue microparticles pathways angiotensin converting enzyme 2 resistance esRAGE interleukins metabolic syndrome dissolution rate thermogenesis streptozotocin bioavailability solubility metabolism renin-angiotensin system microbiota Sirt-1 magnesium dihydroxide hypertrophy metabolic diseases physiological adaption red wine extract lens distribution MTA1 sirtuin inflammation cardiac function rats cisplatin resveratrol mitochondria breast cancer ischemia-reperfusion cardiovascular metabolites gut microbiota prostate cancer performance type 2 diabetes cafeteria diet high-fat high-sucrose diet resistance exercise aging diabetes oxidative stress |
| ISBN | 3-03921-276-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346854603321 |
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Fernandez-Quintela Alfredo
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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JCM-Advances in Cardiology
| JCM-Advances in Cardiology |
| Autore | Henein Michael |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (118 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
ST segment elevation myocardial infarction
COVID-19 primary percutaneous intervention Coptic clergy mortality cardiovascular risk factors prevalence major adverse events obesity ACE2 renin-angiotensin system extraction reimplantation pacing ICD CRT dilated cardiomyopathy (DCM) LMNA lamin A lamin C next generation sequencing (NGS) myocarditis arrhythmias telemonitoring implantable cardioverter defibrillator implantable loop recorder Holter ECG metabolic-dysfunction-associated fatty liver disease (MAFLD) hepatic steatosis SteatoTest adipokines adiponectin visfatin cardiovascular disease |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566459203321 |
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Henein Michael
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neurotransmitter-Related Molecular Modeling Studies
| Neurotransmitter-Related Molecular Modeling Studies |
| Autore | Nowaczyk Alicja |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
white matter hyperintensities
dysautonomia genetic polymorphisms dementia levodopa renin-angiotensin system orthostatic hypotension reserpine-induced fibromyalgia model vortioxetine ropinirole serotonin and dopamine in fibromyalgia mouse dopamine acetylcholine glutamate BDNF serotonin neurotransmitters statins neurodegenerative diseases stroke depression androgenetic alopecia 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors mixed dyslipidemia risk factors halogenated pyrazolines monoamine oxidase inhibitors kinetics reversibility molecular dynamics guanylate cyclase (GC) chronic heart failure (CHF) pulmonary arterial hypertension (PAH) tiagabine cardiac voltage-gated ion channels molecular modeling ECG study SGLT2i sodium-glucose cotransporter 2 inhibitors neuroprotection atheroprotection mTOR type 2 diabetes mellitus cognitive impairment inflammation oxidative stress antibiotics neurotoxicity adverse drug reaction neurotransmission 5-HT receptors gastrointestinal tract |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213903321 |
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Nowaczyk Alicja
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Treatment Strategies for Glioblastoma
| Novel Treatment Strategies for Glioblastoma |
| Autore | Stylli Stanley |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (268 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
glioblastoma
glioma temozolomide radiotherapy immunotherapy novel therapy personalized treatment drug repurposing invasion invadopodia ion channels gene therapy viral vectors brain tumor nanomedicine cancer stem cell targeted therapy brain cancer cell cycle differentiation proliferation RAS SRGAP2 stem cell TP53 glioblastoma multiforme GBM nerve/glial antigen 2 NG2 CK2 CX-4945 migration CRISPR/Cas9 anticancer anti-angiogenesis thyrointegrin αvβ3 PEG triazole tetrac P-bi-TAT P-m-TAT tetrac one-carbon metabolism de novo purine synthesis metabolic reprogramming metabolic treatment vaccine immune checkpoint inhibitors chimeric antigen receptor (CAR) T cells glioblastoma (GB) prolyl-oligopeptidase (POP) vascular endothelial growth factor (VEGF) transforming growth factor-β (TGF-β) angiopoietin (Ang) endothelial nitric oxide synthase (eNOS) newly diagnosed glioblastoma recurrent glioblastoma new trial design drug-inducible gene expression Mardepodect Regorafenib drug targets tumor antigens renin-angiotensin system pluripotent stem cells organoids cancer stem cells cancer stem cell niche tumor microenvironment |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557363703321 |
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Stylli Stanley
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Placental Related Disorders of Pregnancy
| Placental Related Disorders of Pregnancy |
| Autore | Mistry Hiten D |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (378 p.) |
| Soggetto topico |
Medicine
Physiology |
| Soggetto non controllato |
low-dose aspirin
preeclampsia placenta eicosanoids sphingolipids thromboxane prostacyclin isoprostanes neutrophils protease-activated receptor 1 cold shock protein intrauterine growth restriction placentation apoptosis NF-κB hypertension in pregnancy angiogenesis endothelial function oxidative stress antioxidants post-maturity senescence pre-eclampsia renin-angiotensin system megalin proton pump inhibitors telomere shortening prenatal depression sex differences flow culture system explant culture under flow placental insufficiency SPINT2/HAI-2 foetal growth restriction small for gestational age placentome pregnancy nutrient restriction gene expression transcriptome spontaneous preterm birth bioenergetic metabolism interactome fetal sex disparity CD24 cytotrophoblast syncytiotrophoblast immunohistochemistry quantitative polymerase chain reaction (qPCR) immune tolerance inflammation cytokines adipokines antimicrobial peptides metabolic stress IGF-I insulin lactotroph hormones decidual reaction fetal membranes placental hormones primates uterine spiral artery uterine NK cell chorionic somatomammotropin blood flow nutrient uptake uterus ERAP2 trophoblast cells RNA sequencing differentially expressed genes congenital heart disease hand1 vascular development intrahepatic cholestasis of pregnancy human placenta bile acids transporters pregnancy complications metabolism glycolysis mitochondrial respiration placental metabolism trophoblast glycolysis trophoblast mitochondrial respiration sexual dimorphism Interleukin-15 CD122 natural killer cells macrophages trophoblast Irisin TRPV6 calcium transport skeletal dysplasia serine proteases subunit assembly transient receptor potential antioxidant capacity decidua fetal growth restriction KEAP1 NRF2 |
| ISBN | 3-0365-5899-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639995303321 |
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Mistry Hiten D
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2
| Role of Natural Bioactive Compounds in the Rise and Fall of Cancers : Volume 2 |
| Autore | Luparello Claudio |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (318 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
berberine
signaling pathways oncogenic cascades TRAIL microRNAs cancer therapy colon cancer cells ethanol Nrf2 HO-1 ER stress autophagy MMPs formononetin cancer preclinical models cell signaling angiogenesis nobiletin colorectal cancer chemoprevention bioactivities experimental therapeutics HDAC multiple myeloma oleacein breast cancer persistent organic pollutants breast cancer risk breast cancer prognostic systematic review carrageenan invasion metastasis RacGAP1 radiotherapy marine sponge natural product anticancer drug oral cancer inhibition phytochemicals small organic agents Piper eriopodon, alkenylphenols human cancer cells cell death apoptosis caspase-independent cell death XIAP antagonists XIAP-BIR3 domain Calocedrus formosana lung cancer yatein cell-cycle arrest xenograft isorhamnetin G2/M arrest ROS AMPK pancreatic cancer epigallocatechin-3-gallate (EGCG) gemcitabine glycolysis phosphofructokinase natural polyphenols anticancer activities molecular mechanisms Streptomyces mangrove anti-proliferative colon cancer epithelial mesenchymal transition inflammation malignant cancer natural anti-inflammatory compounds pro-resolving lipids anticancer drugs flavonoids natural compounds Xenopus laevis AOM/DSS model melanoma cells nicotine α9-nAChR PD-L1 STAT3 gigantol AKT JAK/STAT cancer stem cell tumor maintenance tumor density proteomics honokiol anticancer mechanism signalling pathway uterine sarcoma fucoidan isobolography colchicine alkaloid mesoporous silica nanoparticles targeted delivery system PD-1 immune checkpoint inhibitor and cancer immunotherapy glucose transport drugs innate immunity β-glucans nutrition immunotherapy estrogen estrogen receptor alpha polyphenols daidzein daidzein metabolites paclitaxel breast cancer cells obesity renin-angiotensin system eicosapentaenoic acid adipocyte inflammation olive leaf extract oleuropein Seahorse analysis cancer metabolism glycolytic markers Malva pseudolavatera Webb & Berthel acute myeloid leukemia reactive oxygen species brain cancer gliomas schwannomas malignant tumors of the peripheral nerve sheath (MPNST) neurofibromas bioavailability nanoparticle-based delivery systems natural bioactive compound gallic acid EGFR signaling p53 EGCG non-coding RNAs anti-cancer drug NSCLC EGFR TKI FASN inhibitors resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Role of Natural Bioactive Compounds in the Rise and Fall of Cancers |
| Record Nr. | UNINA-9910557476303321 |
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Luparello Claudio
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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