Anti-aging Nutrients with Health Beneficial Effects |
Autore | Katakura Yoshinori |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (202 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
Soggetto non controllato |
raw-milk cheese
Caenorhabditis elegans longevity oxidative stress DAF-16 p38 MAPK anthocyanins structure glucose and lipid metabolism human health meta-analysis telomerase reverse transcriptase keratinocyte–hair follicle stem cell interaction exosomes telogen–anagen transition hair cycle regulation caffeine intestinal aging anti-aging vitellogenesis mitochondrial function oxidative stress response GABA exosome gut-brain interaction Caco-2 SH-SY5Y argan press-cake MITF JNK cAMP/PKA Wnt/β-catenin microarray analysis maslinic acid muscle atrophy muscle strength denervation olive peel SGLT1 transporter tangeretin cardamonin intestinal epithelial cell Phgdh liver l-serine deficiency insulin signaling glucose tolerance inflammaging aging related disorders low grade inflammation nutrients natural herbs pro-inflammatory cytokines regulatory T cells retinaldehyde dehydrogenase IgA quercetin luteolin |
ISBN | 3-0365-5070-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910619467703321 |
Katakura Yoshinori | ||
MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Diabetology: Feature Papers 2021 |
Autore | Clifton Peter |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (158 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
carpal tunnel syndrome
ultrasound power doppler signal diabetes FINDRISC prediabetes metabolic syndrome young-adults N-acetyl-β-d-glucosaminidase (NAG) diabetic nephropathy chronic kidney disease (CKD) meta-analysis systematic review focus groups self-management of type 2 diabetes patients' experiences healthcare professionals middle-aged population type 1 diabetes autoimmune diseases pancreatic β-cells tolerance regulatory T cells immunotherapy insulin banting best MacLeod collip limited-resource countries (LRC) insulin pumps blood glucose monitoring continuous blood glucose sensors COVID-19 SARS-CoV-2 ACE2 TMPRSS2 mucormycosis COVID-associated mucormycosis (CAM) mucins Diabetic Keto Acidosis (DKA) Metabolic-Stress-Associated Interactome (MSAI) olfactory neurovascular niche serine proteases ferroptosis redox-iron stress |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Diabetology |
Record Nr. | UNINA-9910576881103321 |
Clifton Peter | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Immunotherapy, Tumor Microenvironment and Survival Signaling |
Autore | Golubovskaya Vita |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (376 p.) |
Soggetto topico |
Medicine
Clinical & internal medicine |
Soggetto non controllato |
Autophagy
colorectal cancer immunotherapy tumor stroma tumor microenvironment immune checkpoint inhibitors chemotherapy tyrosine kinase inhibitors angiogenesis check point inhibitors programmed cell death protein 1 programmed cell death 1 ligand 1 cardiotoxicity lung metastasis CAR-T hypoxia tumor microenvironment CD19 BCMA cancer melanoma immune escape antigen loss chimeric antigen receptor electroporation lentivirus lentiviral transduction macrophages leukemia cells lytic peptides targeted therapy dendritic cells pathogenesis risk factors breast cancer resistance checkpoint targeted treatment personalized medicine pediatric solid tumors chimeric antigen receptors cancer vaccines oncolytic viral therapy immunomodulation DCLK1 tumor stem cells clonogenicity mitochondria mitochondrial transfer tunneling nanotubes triple-negative breast cancer immune checkpoint inhibitor combination therapy cancer nanomedicine tumor antigens cancer metabolism cancer immunotherapy nanoparticles immunotherapeutic agent immunomodulators tuft cells cancer stem cells immunotherapies myeloid-derived suppressor cells regulatory T cells crosstalk tumor immune evasion cell-cell contact β2 integrins CD18 CD11 CAR-T cells CD37 cell therapy tumor antigen lymphoma CAR macrophage CAR T cell solid tumors immunometabolism miRNA immunogenic cell death |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910580205403321 |
Golubovskaya Vita | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
mTOR Signaling in Metabolism and Cancer |
Autore | Huang Shile |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
Descrizione fisica | 1 electronic resource (204 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
mTOR
histone deacetylase prostate cancer integrins adhesion invasion cell metabolism T cells Foxp3 Acute Lymphoblastic leukemia targeted therapy metabolism cell signalling mTOR signalling head and neck cancer mutant genes biomarkers targeted therapies clinical trials cancers inhibitors photodynamic therapy PI3K Akt skin cancers phytochemicals melanoma basal cell carcinoma squamous cell carcinoma Merkel cell carcinoma TNBC eribulin PI3K/AKT/mTOR everolimus combination synergy mTOR signaling tissue regeneration neuron muscle liver intestine hematologic malignancies regulatory T cells tumor |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557107203321 |
Huang Shile | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Oligonucleotide, Therapy, and Applications |
Autore | Aliño Salvador |
Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (123 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
quantum dots (QDs)
DNAzyme ROS Amplex Red light-induced activity DNA methylation histone code microRNA nanoparticles noncoding RNA pulmonary arterial hypertension aptamer aptasensor influenza SERS virus detection α-synuclein antisense oligonucleotide dopamine neurotransmission double mutant A30P*A53T* motor deficits Parkinson’s disease transgenic mouse model G-quadruplexes covalent dimer construct anti-proliferative activity primary cell culture of human glioma antisensense oligonucleotide Foxp3 regulatory T cells vaccine immunogenicity Sporothrix schenckii Marfan syndrome fibrillin-1 antisense oligonucleotides exon skipping splice-switching |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557615903321 |
Aliño Salvador | ||
Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
PPARs as Key Mediators of Metabolic and Inflammatory Regulation |
Autore | Vázquez-Carrera Manuel |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
Descrizione fisica | 1 electronic resource (456 p.) |
Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
Soggetto non controllato |
nuclear receptor
gene transcription inflammation molecular docking PPARβ/δ lung pulmonary artery GW0742 GSK3787 docking lipopolysaccharide (LPS) PPARγ ligand coumarin fluorescent ligand screening crystal structure PPAR atopic dermatitis psoriasis metabolic reprograming glucose fatty acids mycobacteria M. tuberculosis M. leprae PPARs lipid droplets metabolic alterations hepatic damage nuclear factors pharmacological targets AMPK GDF15 insulin resistance type 2 diabetes mellitus peroxisome proliferator-activated receptor gamma (PPARγ) real-time PCR ELISA immunohistochemistry signaling pathway PPAR gamma brain neural stem cells infection neuroinflammation HIV Zika cytomegalovirus neurogenesis microglia liver damage toll-like receptor 4 P2Y2 receptor metabolic syndrome resveratrol quercetin PPARα peroxisome β-oxidation PPRE ligand coregulator micronutrients PPARα knockout adipose tissue browning lipid metabolism depression PPARg neuropathology corticotropin releasing hormone norepinephrine subgenual prefrontal cortex amygdala nucleus accumbens common carotid artery occlusion electroretinography fibroblast growth factor 21 pemafibrate peroxisome proliferator-activated receptor alpha retinal ischemia skeletal muscle substrate metabolism nonalcoholic fatty liver disease (NAFLD) sex dimorphism lipidomics hepatic sex-biased gene expression PPARγ pulmonary arterial hypertension TGFβ vascular injury proliferation kidney fibrosis pattern-recognition receptors phagocytosis nitric oxide synthase fenofibrate oleoylethanolamide palmitoylethanolamide cancer immunity obesity diabetes miRNA DNA methylation histone modification peroxisome-proliferator-activated receptor fatty acid oxidation doping control regulatory T cells exercise nuclear receptors nutrigenomics energy homeostasis dairy animals non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) peroxisome proliferator-activated receptors (PPAR) bezafibrate fenofibric acid peroxisome proliferator-activated receptor dual/pan agonist X-ray crystallography |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910576873703321 |
Vázquez-Carrera Manuel | ||
MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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T Cell Regulation by the Environment |
Autore | Anne L. Astier |
Pubbl/distr/stampa | Frontiers Media SA, 2015 |
Descrizione fisica | 1 electronic resource (115 p.) |
Collana | Frontiers Research Topics |
Soggetto non controllato |
regulatory T cells
Vitamin D helminth T cells Metabolism microbiome |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910136800303321 |
Anne L. Astier | ||
Frontiers Media SA, 2015 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The Immunobiology of HLA-Haploidentical Hematopoietic Cell Transplantation |
Autore | Mancusi Antonella |
Pubbl/distr/stampa | Frontiers Media SA, 2020 |
Descrizione fisica | 1 electronic resource (153 p.) |
Soggetto topico |
Medicine
Immunology |
Soggetto non controllato |
haploidentical transplantation
T-cell depleted grafts T-cell-replete grafts post-transplantation cyclophosphamide immune reconstitution adoptive cell therapy regulatory T cells immune evasion |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557553203321 |
Mancusi Antonella | ||
Frontiers Media SA, 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The Shaping of Cancer by the Tumour Microenvironment and Its Relevance for Cancer Therapy |
Autore | Madureira Patrícia Alexandra Saraiva |
Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
Descrizione fisica | 1 electronic resource (307 p.) |
Soggetto topico | Medicine |
Soggetto non controllato |
hypoxia
macrophages colon cancer tumor microenvironment immune cell infiltration prognosis feline mammary carcinoma PD-1 PD-L1 CTLA-4 TNF-α biomarkers immunotherapy cancer histone modification inhibitor KDM5B molecular docking repurposing cancer acidity hyperosmolarity cross-presentation tumour microenvironment syngeneic model prostate cancer radiotherapy preclinical modelling myeloid-derived suppressor cells biomarker stroma cancer-associated fibroblast (CAF) extracellular matrix (ECM) cytokine/chemokine growth factors pro- and anti-tumor immune cells immunomodulatory roles radiotherapy dose fractionation radioresistance radiosensitivity breast cancer S100A10 (p11) tumor growth tumor progression metastasis carcinoma mammary gland triple negative pre-metastatic niche pro-inflammatory cytokines clinical trials evolutionary therapy darwinian evolution cancer cells subpopulations diclofenac koningic acid spheroid 3D co-culture microenvironment resistance myeloid cells cancer development molecular subtypes of pancreatic cancer chemotherapy response pancreatic stellate cells regulatory T cells tumor-associated macrophages myeloid derived suppressor cells glioblastoma (GB) Hypoxia Inducible Factor (HIF) glioma stem cells (GSC) oxidative stress reactive oxygen species plasmin plasminogen S100A10 uPA uPAR PAI-1 PAI-2 cancer stem cells cancer recurrence therapeutic resistance signaling pathways targeted therapy head and neck cancer lung cancer bladder cancer |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910557354203321 |
Madureira Patrícia Alexandra Saraiva | ||
Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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TRP Channels in Health and Disease |
Autore | Dietrich Alexander |
Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
Descrizione fisica | 1 electronic resource (266 p.) |
Soggetto non controllato |
transient receptor potential channels
photochromic ligands elementary immunology Purkinje cell EPSC substance P chemicals organ toxicity lymphocytes HSP70 physiology bioavailable inflammatory bowel disease platelets pollutants yeast regulatory T cells kinase Saccharomyces cerevisiae manganese cerebellum TRP channel NHERF inflammation nanoHPLC-ESI MS/MS TRPM7 chemical probes TRPM8 dorsal column nuclei TRPV2 TRPV3 calcitonin gene-related peptide TRPV1 ion channels transient receptor potential 2D gel electrophoresis MALDI-TOF MS(/MS) TRPV4 overproduction sulfur mustard oxidative stress graft versus host disease menthol topical chemosensor AP18 calcium signalling mucosal epithelium cuneate nucleus production platform TRPC channels ulcerative colitis channel structure xerostomia neutrophils cardiovascular system TRPC5 TRPC6 TRPC3 TRPC4 calcium signaling protein purification adipose tissue transient receptor potential (TRP) channels sodium TH17 diacylglycerol hypersensitivity TRPY1 GABAB HEK293 thrombosis ion channel TRPC pathophysiology SMAD toxicology endothelium calcium proteomics TRPA1 salivary glands TRP channels lipid mediators sensors radiation TRPM4 channel human medulla oblongata mGluR1 small molecules TRPC3 pharmacology |
ISBN | 3-03921-083-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910674009603321 |
Dietrich Alexander | ||
MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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