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Animal Modeling in Cancer
| Animal Modeling in Cancer |
| Autore | Korinek Vladimir |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (273 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
soy
isoflavones mammary tumor prevention rodent models chemical carcinogens transgenic mice Zebrafish Drosophila rats mice NPM-1 FLT3 ITD ETO-1 IDH1/2 neural stem cells brain and nervous system cancers neurogenic niches radiotherapy sparing of neurogenic regions carcinoma consensus molecular subtypes intestine oncogenes signaling cascades tumor suppressors tumorigenesis MPN (myeloproliferative neoplasms) zebrafish iPSCs JAK2 MPL CALR thrombosis ubiquitin–proteasome system cancer mouse model gene inactivation colorectal cancer mouse models microbiota antitumor immunity melanoma mutation genetics animal model swine MeLiM progression spontaneous regression devitalization metaplasia Cdx animal models epigenetics xenotransplantation drug screen pre-clinical cancer model non-mouse models gene editing stem cells solid tumors hematologic malignancies |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557344403321 |
Korinek Vladimir
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Benefits of Resveratrol Supplementation / María P. Portillo, Alfredo Fernandez-Quintela
| Benefits of Resveratrol Supplementation / María P. Portillo, Alfredo Fernandez-Quintela |
| Autore | Portillo María P |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI, , 2019 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto non controllato |
polyphenols
?-viniferin leptin resistance p53 kidney energy restriction grape powder extract cytokines phosphorylation obesity energy metabolism metabolic pathways endothelial function polyol pathway antioxidant caloric restriction rat adipose tissue microparticles pathways angiotensin converting enzyme 2 resistance esRAGE interleukins metabolic syndrome dissolution rate thermogenesis streptozotocin bioavailability solubility metabolism renin-angiotensin system microbiota Sirt-1 magnesium dihydroxide hypertrophy metabolic diseases physiological adaption red wine extract lens distribution MTA1 sirtuin inflammation cardiac function rats cisplatin resveratrol mitochondria breast cancer ischemia-reperfusion cardiovascular metabolites gut microbiota prostate cancer performance type 2 diabetes cafeteria diet high-fat high-sucrose diet resistance exercise aging diabetes oxidative stress |
| ISBN |
9783039212767
3039212761 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346854603321 |
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Portillo María P
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| Basel, Switzerland : , : MDPI, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Beta-Glucan in Foods and Health Benefits
| Beta-Glucan in Foods and Health Benefits |
| Autore | Aoe Seiichiro |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (194 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
humans
oat β-glucan acute glycemic response dietary fiber preload carbohydrates β-1,3-glucan Euglena gracilis Ca2+ signaling intestinal epithelial cell intravital imaging small intestine immune system barley β-glucan microarray short chain fatty acids lipid metabolism low molecular weight fermentation prebiotics Autreobasidium pullulans β-1,3-1,6-glucan physiological function oat beta-glucan colitis Crohn's disease apoptosis autophagy TLRs Dectin-1 rats L cell glucagon-like peptide 1 (GLP-1) glucose tolerance short-chain fatty acids sIgA microbiota randomized clinical trial symptoms gastrointestinal tract musculo-skeletal system oats oatmeal beta-glucan beta glucan health claim regulation food-health relationship gastritis inflammatory process antioxidant properties paramylon abdominal fat DNA microarray gene ontology PPAR signaling |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595070503321 |
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Aoe Seiichiro
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diets, Foods and Food Components Effect on Dyslipidemia
| Diets, Foods and Food Components Effect on Dyslipidemia |
| Autore | Fogacci Federica |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (300 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
beta-glucan
fiber lipid profile cholesterol intestinal function green tea epigallocatechin gallate chitosan microspheres Eudragit metabolic diseases LCD score CHNS dyslipidemia dietary factor plant based animal based Chinese adults nutraceuticals PCSK9 SREBP HNF1α berberine metabolic syndrome plant extracts natural antioxidant polyphenols bergamot blackcurrant liver steatosis ovariectomized phytoestrogen vitamin B12 healthy Saudi Arabia serum cholesterol serum triglycerides serum low density lipoprotein serum high density lipoprotein dietary intake lifestyle black raspberry excessive choline TMAO hypercholesterolemia hepatic inflammation review CVD cardiovascular health dietary fats dietary fiber phytosterols plant-based diet dietary pattern sustainability propolis formononetin gastric ulcer rats Chrysanthemum morifolium Ramat leaves obesity lipidomics liquid chromatography tandem mass spectrometry phospholipid sphingolipid monacolins LDL-cholesterol red yeast rice clinical trial endothelial function alpha-linolenic acid flaxseed lipids omega-3 walnuts type 2 diabetes mellitus glibenclamide omega-3 fatty acids high fat diet transcription factors streptozotocin Armolipid Plus® nutraceutical supplementation blood pressure fasting plasma glucose |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557599803321 |
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Fogacci Federica
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Metabolism/Transport and Pharmacokinetics
| Drug Metabolism/Transport and Pharmacokinetics |
| Autore | Song Im-Sook |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (232 p.) |
| Soggetto topico |
Medicine
Pharmaceutical industries |
| Soggetto non controllato |
tofacitinib
dose-dependent pharmacokinetics hepatic and intestinal first-pass effect rats catalposide in vitro human metabolism UDP-glucuronosyltransferase sulfotransferase carboxylesterase celecoxib drug–drug interaction fluorescence HPLC metabolism repaglinide HSG4112 anti-obesity agent stereoselectivity pharmacokinetics compound K protopanaxadiol (PPD) biliary excretion intestinal metabolism Carthamus tinctorius extract notoginseng total saponins comparative pharmacokinetic study large volume direct injection compatibility mechanism mertansine human hepatocytes cytochrome P450 UDP-glucuronosyltransferases sodium-glucose cotransporter 2 (SGLT2) inhibitors DWP16001 kidney distribution inhibition mode diabetes transporter-enzyme interplay influx transporter efflux transporter physiologically based pharmacokinetic model cytochrome P450 enzymes tiropramide healthy Korean subjects modeling population pharmacokinetic quercetin breast cancer resistance protein inhibitor prazosin sulfasalazine kinetic analysis food–drug interactions Caco-2 EpiIntestinal first-pass P-gp BCRP drug transporter CYP3A4 oral availability automatization drug absorption drug dosing head-and-neck cancer real-time measurements taxanes tissue engineering UHPLC-MS/MS metformin verapamil drug interaction organic cation transporter 2 renal excretion acute renal failure gentamicin cisplatin hepatic CYP3A1(23) creatinine clearance renal clearance nonrenal clearance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607703321 |
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Song Im-Sook
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Freshwater Algal Toxins : Monitoring and Toxicity Profile
| Freshwater Algal Toxins : Monitoring and Toxicity Profile |
| Autore | Cameán Ana M |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (208 p.) |
| Soggetto topico |
Research & information: general
Environmental economics |
| Soggetto non controllato |
inflammatory bowel disease
dextran sulfate sodium colitis microcystin colon HAB Adda canine intoxication MMPB urinalysis hair ELISA LC-MS/MS Microcystin-LR Non-alcoholic Fatty Liver Disease No Observed Adverse Effect Level Leprdb/J mice hepatotoxicity oxidative stress TiO2 enriched phosphopeptides Cyanotoxins microcystin congeners MC-LA nutrients climate Great Lakes raw water intake multivariate statistics long-term monitoring cyanobacteria microcystin-LR cylindrospermopsin cyanotoxins mixture plant growth toxin bioaccumulation cyanotoxin structure PP2A inhibition liquid chromatography mass spectrometry cyanotoxins metal zinc Microcystis aeruginosa in vivo genotoxicity micronucleus comet assay enzyme-modified comet assay rats drinking water quality Mozambique public health Llayta Nostoc flow cytometry liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) risk assessment management strategies modelling |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Freshwater Algal Toxins |
| Record Nr. | UNINA-9910557112703321 |
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Cameán Ana M
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neuroendocrine Control of Energy Metabolism
| Neuroendocrine Control of Energy Metabolism |
| Autore | Panzica Giancarlo |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (240 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
IGF1
IGF2 IGFBP2 high-fat diet obesity sex differences neuropeptides beige adipocyte white adipocyte brown adipocyte diabetes mellitus differentiation kisspeptin AgRP sheep reproduction LH genistein proopiomelanocortin arcuate nucleus rats endocrine disrupting chemicals bisphenol A diethylstilbestrol tributyltin neuropeptide Y pro-opiomelanocortin phytoestrogens endocrine disruptor dimorphism POMC orexin subfornical organ organum vasculosum of the lamina terminalis area postrema hypothalamus metabolism diabetes estrogens gut permeability/integrity insulin sensitivity Akkermansia gut microbiome lactate glycogen behavior learning astrocytes calcium signaling energy balance gliotransmission systemic metabolism amygdala kisspeptins food intake body weight intrauterine growth restriction macrosomia glucose tolerance abdominal adipocyte gene expression thrifty phenotype hypothesis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566462903321 |
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Panzica Giancarlo
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Potential Health Benefits of Fruits and Vegetables
| Potential Health Benefits of Fruits and Vegetables |
| Autore | Mazzoni Luca |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (210 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Technology, engineering, agriculture |
| Soggetto non controllato |
ABTS
bioactive compounds DPPH flavonoids genetic distance genotypic and phenotypic correlation nutraceutical value phenolics UPGMA apricot methyl jasmonate salicylic acid antioxidant property enzyme activity postharvest quality elderberry reishi respiratory tract infections common cold influenza-like illness respiratory infection symptoms randomized controlled trial agrobiodiversity antioxidant activity health benefits medicinal properties Mediterranean diet market food trends sustainability wild edible greens organic farming conventional farming trace elements heavy metals risk assessment anthocyanins Fragaria × ananassa latitude temperature global radiation cultivar × environmental interaction phytochemical compounds antioxidant capacity Brassica spp vegetables cultivation techniques glucosinolates apple royal gala pink lady red delicious smitten fuji phenolic compounds LC-ESI-QTOF-MS/MS HPLC garlic Allium sativum thiosulfinate allicin sepsis immunomodulation interleukins rats hydroxytyrosol olive extract olive polyphenols grape extract oleuropein F2-isoprostanes AGEs Gynura bicolor prediabetes phytochemical blood glucose oxidative stress |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557572403321 |
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Mazzoni Luca
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Studies of Rodent Ultrasonic Vocalizations and Their Use in Experimental Models
| Recent Studies of Rodent Ultrasonic Vocalizations and Their Use in Experimental Models |
| Autore | Brudzynski Stefan M |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (352 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
ultrasonic vocalization
maternal immune activation autism communication rat sex differences social play rats anxiety observational fear learning USV maternal separation pup vasopressin antagonists righting reflex negative geotaxis ACTH corticosterone Brattleboro rat larynx female male 50-khz ultrasonic vocalizations (USVs) individual differences chronic variable stress (CVS) dopamine nucleus accumbens microdialysis evolution of vocalization 22 kHz calls 50 kHz calls infant isolation calls emotional arousal mesolimbic dopaminergic system mesolimbic cholinergic system hedonia ultrasonic vocalizations cognitive development respiration brain oscillations Cav1.2 calcium animal model rough-and-tumble play social approach playback social contact call alarm call social buffering distress emotional contagion fear contagion aversive state automated scoring addiction mental health machine learning drug discovery drug development Parkinson's disease alpha-synuclein 6-OHDA Pink1 DJ1 exercise pharmacology pathology hypervigilance hyperreactivity exaggerated reactivity generalization PTSD depression heart rate Wistar 22-kHz calls 50-kHz calls affect aversion NOR reward working memory Y maze opioids fentanyl self-administration play food dam-pup interaction ethanol pup isolation rat pup 50 kHz vocalizations 22 kHz vocalizations amphetamine chemogenetics clozapine-n-oxide UMAP males females vocalizations fear extinction pain |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557608903321 |
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Brudzynski Stefan M
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Trends in Pharmaceutical Analytical Chemistry
| Recent Trends in Pharmaceutical Analytical Chemistry |
| Autore | Zacharis Constantinos K |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (166 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
growth hormone
long-acting Fc-fusion recombinant human growth hormone method validation cell-based bioassay reporter gene assay pharmacokinetics tissue distribution alnustone rats LC-MS/MS inflammatory bowel disease fixed-dose combination biomimetic chromatography thiopurine immunosuppressants folic acid doxorubicin hernandezine pharmacokinetic study drug-drug interaction gardneramine monoterpenoid indole alkaloid memantine rimantadine amantadine zone fluidics o-phthalaldehyde derivatization stopped-flow quality control anwuligan rat optode polyhexamethylene biguanide hydrochloride lactone-rhodamine B contact-lens detergent dietary supplement adulteration low-field NMR multivariate analysis steroids Partial Least Squares regression in vitro permeability predictive model ketamine norketamine high throughput bar adsorptive microextraction LVI-GC-MS(SIM) urine baricitinib UPLC-MS/MS irbersartan |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557427303321 |
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Zacharis Constantinos K
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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