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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (528 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
melanoma
invasion WNT5A MARCKS phosphorylation MANS peptide nanoparticles cell therapy tumor microenvironment sex/gender sex-hormones immunity microRNAs immunotherapy BRAF-mutant melanoma BRAF inhibitor mechanism of action targeted therapy tumour microenvironment plasmacytoid dendritic cells lactate dehydrogenase TLR interferon CXCL10 TPC2 HIPPO SOCE metastasis essential oils angiogenesis apoptosis uveal melanoma (UM) metastatic uveal melanoma (mUM) prognostication adjuvant therapy metastatic therapy metastatic dormancy liver-directed-therapies targeted-therapy combined therapy protein tyrosine phosphatase PTPs inhibitors melanoma immune infiltrate BRAF inhibitors microenvironment resistance therapy therapeutic resistance exosomes extracellular vesicles diagnosis prognosis ctDNA liquid biopsy prediction patient stratification BRAF arthralgia rheumatoid arthritis carbonic anhydrase hedgehog cyclopamine small molecules acetazolamide motility metalloproteinases FAK cancer mucosal melanoma nivolumab pembrolizumab ipilimumab radiotherapy cholinergic system acetylcholine muscarinic receptors nicotinic receptors melanoma metastasis ShcD adaptor protein amoeboid motility Rac1 DOCK4 melanoma PDX target therapy cancer stem cells slow cycling phenotype drug resistance OXPHOS lipid metabolism cancer associated fibroblast melanomagenesis biomarkers checkpoint inhibitor PD-1 melanoma markers cytokines machine learning Support Vector Machine principal component analysis BCL2L10 STAT3 cytotoxicity survival ABT-737 Bcl-2 family ML258 HuR MITF metastases siRNA |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Animal Modeling in Cancer
| Animal Modeling in Cancer |
| Autore | Korinek Vladimir |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (273 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
soy
isoflavones mammary tumor prevention rodent models chemical carcinogens transgenic mice Zebrafish Drosophila rats mice NPM-1 FLT3 ITD ETO-1 IDH1/2 neural stem cells brain and nervous system cancers neurogenic niches radiotherapy sparing of neurogenic regions carcinoma consensus molecular subtypes intestine oncogenes signaling cascades tumor suppressors tumorigenesis MPN (myeloproliferative neoplasms) zebrafish iPSCs JAK2 MPL CALR thrombosis ubiquitin–proteasome system cancer mouse model gene inactivation colorectal cancer mouse models microbiota antitumor immunity melanoma mutation genetics animal model swine MeLiM progression spontaneous regression devitalization metaplasia Cdx animal models epigenetics xenotransplantation drug screen pre-clinical cancer model non-mouse models gene editing stem cells solid tumors hematologic malignancies |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557344403321 |
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Korinek Vladimir
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Applications of Medical Physics
| Applications of Medical Physics |
| Autore | Gallo Salvatore |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (310 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
medical imaging
radiomics tomosynthesis acquisition angle percutaneous radioablation monte carlo dosimetry liver lesions molecular radiotherapy quality assurance in vivo dosimetry transmission radiation detectors whole breast irradiation MR-guided radiotherapy predictive models cervical cancer EOS conventional radiography computed tomography radiation dose enchondroma phantom medical worker radiological accident emergency response retrospective dosimetry ESR EPR fingernails antioxidant GEMPix GEMs Timepix Medipix radiation therapy hadron therapy microdosimetry gaseous detectors Covid-19 chest CT lungs HU density artificial intelligence deep learning medical physicist machine learning big data radioembolization internal dosimetry Monte Carlo-based dosimetry absorbed dose signal-noise ratio contrast-noise ratio figure of merit robust optimization high dose rate brachytherapy single plan approach median absolute deviation 99mTc-sestamibi breast-specific γ imaging breast cancer apoptosis theragnostic esophageal cancer neoadjuvant chemoradiation squamous cell carcinoma epicardial adipose tissue machine and deep learning partial volume effect quantitative analysis point spread function post-reconstruction-correction-method iterative reconstruction algorithms ASiR ASiR-V noise level noise spatial uniformity in vivo relative dosimetry proton radiotherapy quality controls beam monitoring nanoparticles scintillation ionizing energy deposition photodynamic therapy singlet oxygen protontherapy RBE radiobiology Geant4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580212303321 |
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Gallo Salvatore
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Biomarker Research and Personalized Medicine
| Cancer Biomarker Research and Personalized Medicine |
| Autore | Meehan James |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (428 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
clear cell renal cell carcinoma
radiomics WHO/ISUP nuclear grade multiphasic multidetector computed tomography triple-negative breast cancer taxane chemotherapy GBP5 Akt/mTOR autophagy IL13Rα2 renal cell carcinoma JAK2 FOXO3 telmisartan ovarian cancer bioinformatics CREB1 drug perturbation lincRNA-p21 rectal cancer chemoradiotherapy colorectal cancer long non-coding RNA p53 predictive biomarker intestinal anastomosis anastomotic leak biomarkers precision medicine personalized medicine biomarker AmpliSeq DNA methylation epigenetics head and neck cancer saliva liquid biopsy meta-analysis gastric cancer middle-up-down haptoglobin glycopeptide mass spectrometry circulating tumor cells prostate cancer cancer vaccine immune response breast cancer predictive tools prognostic tools translational research IL6ST gp130 cytokine signalling tissue-based biomarkers liquid-based biomarkers radiotherapy radiosensitivity biomarkers secretome radioresistance bladder tumor lymphocyte-to-monocyte ratio peripheral blood parameters tumor recurrence transurethral resection lipidomics 1H-NMR LC-MS/MS lipoprotein subfractions lipoprotein lipase cancer biomarkers hepatocellular carcinoma p16 expression head and neck squamous cell carcinoma HPV genotyping exosomes chemoresistance comparative oncology One Health microRNA lymph node metastasis hormone-dependent carcinogenesis localized prostate cancer prognostic factors HNSCC |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674370003321 |
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Meehan James
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Nanomedicine
| Cancer Nanomedicine |
| Autore | Hoskins Clare |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (510 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
antibody drug conjugate (ADC)
PD-L1 tumor spheroid disruption immune modulation doxorubicin graphene oxide adsorption cathepsin D cathepsin L anti-metastatic enzyme cancer therapy nanoparticles targeted delivery system siRNA osteopontin mammary carcinoma mesenchymal stem cells (MSCs) TAT peptide PLGA paclitaxel nano-engineered MSCs orthotopic lung tumor model intracranial glioma immunotherapy CPMV viral nanoparticles in situ vaccine albumin nanoparticles microbubble ultrasound theranostics hepatocellular carcinoma VX2 tumor intra-arterial chemotherapy lung cancer nanomedicine clinical status cancer therapy breast cancer cell signaling active targeting passive targeting EPR effect oncogenes nanoparticle drug delivery ligand tumor targeting biodistribution Mesoporous silica nanoparticle drug delivery system target treatment lanthanide metal hyaluronic acid hyaluronidase drug combination everolimus dual-targeting magnetic nanoparticles monoclonal antibodies nanostructured lipid carrier platelet membrane biomimicry plasmonic photothermal therapy gold nanorods surgery bleeding dogs cats stimuli-responsive DOX SN38 CSCs single-walled carbon nanotubes chirality separation NASH drug-gene delivery near IR hyperspectral imaging plasmonics copper VEGF glioblastoma differentiated neuroblastoma peptidomimetics real-time quantitative polymerase chain reaction (qPCR) actin combinatorial therapy anticancer and antibacterial activity temoporfin drug-in-cyclodextrin-in-liposome hybrid nanoparticles multicellular tumor spheroids cyclodextrins photodynamic therapy article yet reasonably common within the subject discipline antitumor strategy biomimetic core–shell nanoparticles NK cell-derived exosomes folate receptor albumin nanoparticle microfluidic cabazitaxel polydopamine nanoparticles size cytotoxicity iron affinity FA-DABA-SMA self-assembly oncogenic proteins intracellular disruption folic receptor alpha pancreatic cancer parvifloron D albumin erlotinib photodynamic therapy lipid nanoparticles tumor vectorization verteporfin ovarian carcinomatosis spheroids integrin RGD peptide cancer diagnosis radiotherapy hyperthermia therapy biomimetic nanocarrier membrane-wrapped cancer targeted delivery photothermal therapy imaging cancer nanomedicine tumor microenvironment nano–bio interactions clinical translation magnetic nanowires magnetic hyperthermia magnetic actuation magnetic drug targeting titanate nanotubes gold nanoparticles vectorization colloidal stability docetaxel prostate cancer mangiferin anti-topoisomerase activity extracellular vesicles exosomes chemico-physical functionalization loading translational medicine nanotechnology: bioengineering anacardic acid mitoxantrone targeted drug delivery liposomes melanoma apoptosis ascorbic acid angiogenesis epithelial-to-mesenchymal transition hypoxia immunosuppression metabolism nanotherapeutics tumour microenvironment DNA origami liposome remote loading acute toxicity organoids magnetic silica-coated iron oxide nanochains photothermal treatment hyperthermia collagen cellular microenvironment lymphadenectomy magnetometer sentinel lymph node dissection SPION superparamagnetic iron oxide nanoparticles Vδ2 T cells zoledronic acid polymeric nanoconstruct anti-tumor immunity colorectal carcinoma β-cyclodextrin nanosponges BALB-neuT mice brain tumours glioma blood brain barrier polymeric nanoparticles PEGylation dioleoylphosphatidylethanolamine poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer folate oxidation-sensitive release cellular interaction in vitro anti-cancer activity triple negative breast cancer organotin mesoporous silica nanoparticles MDA-MB-231 theranostic nanomaterials nanobiotechnology molecular imaging nanosystems nanomicelles ovarian cancer tumour targeting chemotherapeutics riboflavin vitamin B2 nanomedicines secondary structure mixed micelle pH responsive targeted therapy anti-cancer shear stress flow in vitro therapeutics diagnostics Immunotherapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557114703321 |
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Hoskins Clare
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Charged Particles in Oncology
| Charged Particles in Oncology |
| Autore | Marco Durante |
| Pubbl/distr/stampa | Frontiers Media SA, 2018 |
| Descrizione fisica | 1 electronic resource (650 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
carbon ions
heavy ions Mars proton therapy radiotherapy particle radiobiology protons space radiation protection Charged particles space travel |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346747903321 |
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Marco Durante
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| Frontiers Media SA, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Combinatorial Approaches to Enhance Anti-Tumor Immunity: Focus on Immune Checkpoint Blockade Therapy
| Combinatorial Approaches to Enhance Anti-Tumor Immunity: Focus on Immune Checkpoint Blockade Therapy |
| Autore | Andersson Patrik |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (316 p.) |
| Soggetto topico |
Medicine
Immunology |
| Soggetto non controllato |
cancer
immunotherapy radiotherapy antiangiogenic therapy immune checkpoint blockade (ICB) cancer vaccine |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Combinatorial Approaches to Enhance Anti-Tumor Immunity |
| Record Nr. | UNINA-9910557573503321 |
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Andersson Patrik
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential
| Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential |
| Autore | Pitsikas Nikolaos |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (171 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
saffron
affron® depression anxiety antioxidant crocins glucose β-pancreatic cells insulin pck1 neuroprotective activity P2X7 receptor fraction flumazenil rat Crocus sativus cancer anticancer activity chemoprevention clinical trials patents anesthetic ketamine memory Crocus sativus L. schizophrenia crocetin pubertal testis X-rays radiotherapy fertility preservation SIRT1 HuR oxidative stress autophagy crocin picrocrocin safranal dietary supplement nutraceutical Crocus sativus L. (Iridaceae) reversed-phase UPLC metabolomics HR MS inflammatory bowel disease gut microbiota colitis cytokines colorectal cancer HCT116 MLH1 MSH3 DNA damage and repair apoptosis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Crocus sativus L. Extract and Its Constituents |
| Record Nr. | UNINA-9910557644303321 |
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Pitsikas Nikolaos
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Current Insights on Lipid-Based Nanosystems
| Current Insights on Lipid-Based Nanosystems |
| Autore | Silva Ana Catarina |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
Echinococcus granulosus
scolicidal nanoliposome juglone apoptotic activity hydrogel SLNs nose-to-brain delivery mucoadhesion quality by design antioxidant activity nasal administration nanostructured lipid carriers solid lipid nanoparticles in vitro cell cultures 3D nasal casts lung cancer targeted drug delivery lipid-based nanocarriers pulmonary delivery dry powder inhalers aerosols liposomes nanoemulsions nanotechnology biologically active compounds dermal drug delivery polyphenols phytophenols skin permeation chemotherapy radiotherapy active targeting passive targeting tumor immunoconjugate traditional liposome stealth liposome triggered release limitations of liposomes drug transfer in vitro release colloidal drug carriers lipid nanoparticles hydrogel beads cholesteryl nonanoate bovine serum albumin skin diseases lipid-based nanosystems cream ointment gel pH-sensitive liposome imidazole anticancer drug delivery multicellular spheroids dapagliflozin Box-Behnken design FTIR DSC XRD SEM AFM in vitro Franz diffusion cells lipid-based nanoparticles nanocarrier surface charge delivery systems chronic treatment mice anti-oxidant activity hepatoprotective effect phospholipid phytosomes Silymarin Colorectal Cancer Niosomes Oxaliplatin Paclitaxel d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) therapeutic nucleic acids schizophrenia quetiapine fumarate glycerosomes central composite rotatable design bioavailability pharmacokinetic |
| ISBN | 3-0365-6165-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639995103321 |
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Silva Ana Catarina
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications
| Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications |
| Autore | Ishii Kenichiro |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (184 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
androgen receptor
docetaxel cabazitaxel castration-resistant prostate cancer chemotherapy P-glycoprotein EPI-002 splice variant prostate-specific antigen androgen deprivation therapy time to PSA nadir fibroblasts prostate cancer androgen sensitivity pirfenidone TGFβ1 G1 cell cycle arrest fibroblast growth factor fibroblast growth factor receptor obesity inflammation immune cells cytokine high-fat diet KIFC1 docetaxel resistance apoptosis CW069 Caveolin-1 TP53-regulated inhibitor of apoptosis 1 tumour stroma tumour microenvironment fibroblast CAF resistance radiotherapy CCL2 CCL22 CCL5 migration LSD1 epigenetics autophagy abiraterone enzalutamide testosterone castration resistant prostate cancer animal model diet fat in vitro in vivo mouse AKR1C3 hormone-naïve prostate cancer immunohistochemistry tissue microarray androgen receptor dependency fibroblast-dependent androgen receptor activation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557116703321 |
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Ishii Kenichiro
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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