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Advances and Novel Treatment Options in Metastatic Melanoma
| Advances and Novel Treatment Options in Metastatic Melanoma |
| Autore | Facchiano Antonio |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (528 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
ABT-737
acetazolamide acetylcholine adjuvant therapy amoeboid motility angiogenesis apoptosis arthralgia Bcl-2 family BCL2L10 biomarkers BRAF BRAF inhibitor BRAF inhibitors BRAF-mutant melanoma cancer cancer associated fibroblast cancer stem cells carbonic anhydrase cell therapy checkpoint inhibitor cholinergic system combined therapy ctDNA CXCL10 cyclopamine cytokines cytotoxicity diagnosis DOCK4 drug resistance essential oils exosomes extracellular vesicles FAK hedgehog HIPPO HuR immunity immunotherapy interferon invasion ipilimumab lactate dehydrogenase lipid metabolism liquid biopsy liver-directed-therapies machine learning MANS peptide MARCKS mechanism of action melanoma melanoma immune infiltrate melanoma markers melanoma metastasis melanoma PDX melanomagenesis metalloproteinases metastases metastasis metastatic dormancy metastatic therapy metastatic uveal melanoma (mUM) microenvironment microRNAs MITF ML258 motility mucosal melanoma muscarinic receptors n/a nanoparticles nicotinic receptors nivolumab OXPHOS patient stratification PD-1 pembrolizumab phosphorylation plasmacytoid dendritic cells prediction principal component analysis prognosis prognostication protein tyrosine phosphatase PTPs inhibitors Rac1 radiotherapy resistance rheumatoid arthritis sex-hormones sex/gender ShcD adaptor protein siRNA slow cycling phenotype small molecules SOCE STAT3 Support Vector Machine survival target therapy targeted therapy targeted-therapy therapeutic resistance therapy TLR TPC2 tumor microenvironment tumour microenvironment uveal melanoma (UM) WNT5A |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557612103321 |
Facchiano Antonio
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Animal Modeling in Cancer
| Animal Modeling in Cancer |
| Autore | Korinek Vladimir |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (273 p.) |
| Soggetto topico |
Biology, life sciences
Research & information: general |
| Soggetto non controllato |
animal model
animal models antitumor immunity brain and nervous system cancers CALR cancer carcinoma Cdx chemical carcinogens colorectal cancer consensus molecular subtypes devitalization Drosophila drug screen epigenetics ETO-1 FLT3 ITD gene editing gene inactivation genetics hematologic malignancies IDH1/2 intestine iPSCs isoflavones JAK2 mammary tumor prevention melanoma MeLiM metaplasia mice microbiota mouse model mouse models MPL MPN (myeloproliferative neoplasms) mutation neural stem cells neurogenic niches non-mouse models NPM-1 oncogenes pre-clinical cancer model progression radiotherapy rats rodent models signaling cascades solid tumors soy sparing of neurogenic regions spontaneous regression stem cells swine thrombosis transgenic mice tumor suppressors tumorigenesis ubiquitin-proteasome system xenotransplantation zebrafish Zebrafish |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557344403321 |
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Korinek Vladimir
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Applications of Medical Physics
| Applications of Medical Physics |
| Autore | Gallo Salvatore |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (310 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
99mTc-sestamibi
absorbed dose acquisition angle antioxidant apoptosis artificial intelligence ASiR ASiR-V beam monitoring big data breast cancer breast-specific γ imaging cervical cancer chest CT computed tomography contrast-noise ratio conventional radiography Covid-19 deep learning emergency response enchondroma EOS epicardial adipose tissue EPR esophageal cancer ESR figure of merit fingernails gaseous detectors Geant4 GEMPix GEMs hadron therapy high dose rate brachytherapy HU density in vivo dosimetry in vivo relative dosimetry internal dosimetry ionizing energy deposition iterative reconstruction algorithms liver lesions lungs machine and deep learning machine learning median absolute deviation medical imaging medical physicist medical worker Medipix microdosimetry molecular radiotherapy monte carlo dosimetry Monte Carlo-based dosimetry MR-guided radiotherapy n/a nanoparticles neoadjuvant chemoradiation noise level noise spatial uniformity partial volume effect percutaneous radioablation phantom photodynamic therapy point spread function post-reconstruction-correction-method predictive models proton protontherapy quality assurance quality controls quantitative analysis radiation dose radiation therapy radiobiology radioembolization radiological accident radiomics radiotherapy RBE retrospective dosimetry robust optimization scintillation signal-noise ratio single plan approach singlet oxygen squamous cell carcinoma theragnostic Timepix tomosynthesis transmission radiation detectors whole breast irradiation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580212303321 |
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Gallo Salvatore
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Biomarker Research and Personalized Medicine
| Cancer Biomarker Research and Personalized Medicine |
| Autore | Meehan James |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 online resource (428 p.) |
| Soggetto topico |
Medicine and Nursing
Oncology |
| Soggetto non controllato |
1H-NMR
Akt/mTOR AmpliSeq anastomotic leak autophagy bioinformatics biomarker biomarkers bladder tumor breast cancer cancer biomarkers cancer vaccine chemoradiotherapy chemoresistance chemotherapy circulating tumor cells clear cell renal cell carcinoma colorectal cancer comparative oncology CREB1 cytokine signalling DNA methylation drug perturbation epigenetics exosomes FOXO3 gastric cancer GBP5 glycopeptide gp130 haptoglobin head and neck cancer head and neck squamous cell carcinoma hepatocellular carcinoma HNSCC hormone-dependent carcinogenesis HPV genotyping IL13Rα2 IL6ST immune response intestinal anastomosis JAK2 LC-MS/MS lincRNA-p21 lipidomics lipoprotein lipase lipoprotein subfractions liquid biopsy liquid-based biomarkers localized prostate cancer long non-coding RNA lymph node metastasis lymphocyte-to-monocyte ratio mass spectrometry meta-analysis microRNA middle-up-down multiphasic multidetector computed tomography n/a One Health ovarian cancer p16 expression p53 peripheral blood parameters personalized medicine precision medicine predictive biomarker predictive tools prognostic factors prognostic tools prostate cancer radiomics radioresistance radiosensitivity biomarkers radiotherapy rectal cancer renal cell carcinoma saliva secretome taxane telmisartan tissue-based biomarkers translational research transurethral resection triple-negative breast cancer tumor recurrence WHO/ISUP nuclear grade |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910674370003321 |
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Meehan James
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Nanomedicine
| Cancer Nanomedicine |
| Autore | Hoskins Clare |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (510 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
actin
active targeting acute toxicity adsorption albumin albumin nanoparticle albumin nanoparticles anacardic acid angiogenesis anti-cancer anti-metastatic enzyme cancer therapy anti-topoisomerase activity anti-tumor immunity antibody drug conjugate (ADC) anticancer and antibacterial activity antitumor strategy apoptosis ascorbic acid BALB-neuT mice biodistribution biomimetic biomimetic core-shell nanoparticles biomimicry bleeding blood brain barrier brain tumours breast cancer cabazitaxel cancer cancer diagnosis cancer nanomedicine cancer therapy cathepsin D cathepsin L cats cell signaling cellular interaction cellular microenvironment chemico-physical functionalization chemotherapeutics chirality separation clinical status clinical translation collagen colloidal stability colorectal carcinoma combinatorial therapy copper CPMV CSCs cyclodextrins cytotoxicity diagnostics differentiated neuroblastoma dioleoylphosphatidylethanolamine DNA origami docetaxel dogs DOX doxorubicin drug combination drug delivery drug delivery system drug-gene delivery drug-in-cyclodextrin-in-liposome dual-targeting epithelial-to-mesenchymal transition EPR effect erlotinib everolimus exosomes extracellular vesicles FA-DABA-SMA flow folate folate receptor folic receptor alpha glioblastoma glioma gold nanoparticles gold nanorods graphene oxide hepatocellular carcinoma hyaluronic acid hyaluronidase hybrid nanoparticles hyperthermia hyperthermia therapy hypoxia imaging immune modulation immunosuppression immunotherapy Immunotherapy in situ vaccine in vitro in vitro anti-cancer activity integrin intra-arterial chemotherapy intracellular disruption intracranial glioma iron affinity lanthanide metal ligand lipid nanoparticles liposome liposomes loading lung cancer lymphadenectomy magnetic actuation magnetic drug targeting magnetic hyperthermia magnetic nanoparticles magnetic nanowires magnetic silica-coated iron oxide nanochains magnetometer mammary carcinoma mangiferin MDA-MB-231 melanoma membrane-wrapped mesenchymal stem cells (MSCs) Mesoporous silica nanoparticle mesoporous silica nanoparticles metabolism microbubble microfluidic mitoxantrone mixed micelle molecular imaging monoclonal antibodies multicellular tumor spheroids nano-bio interactions nano-engineered MSCs nanobiotechnology nanocarrier nanomedicine nanomedicines nanomicelles nanoparticle nanoparticles nanostructured lipid carrier nanosystems nanotechnology: bioengineering nanotherapeutics NASH near IR hyperspectral imaging NK cell-derived exosomes oncogenes oncogenic proteins organoids organotin orthotopic lung tumor model osteopontin ovarian cancer ovarian carcinomatosis oxidation-sensitive release paclitaxel pancreatic cancer parvifloron D passive targeting PD-L1 PEGylation peptidomimetics pH responsive photodynamic therapy photodynamic therapy article photothermal therapy photothermal treatment plasmonic photothermal therapy plasmonics platelet membrane PLGA poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer polydopamine nanoparticles polymeric nanoconstruct polymeric nanoparticles prostate cancer radiotherapy real-time quantitative polymerase chain reaction (qPCR) remote loading RGD peptide riboflavin secondary structure self-assembly sentinel lymph node dissection shear stress single-walled carbon nanotubes siRNA size SN38 spheroids SPION stimuli-responsive superparamagnetic iron oxide nanoparticles surgery target treatment targeted delivery targeted delivery system targeted drug delivery targeted therapy TAT peptide temoporfin theranostic nanomaterials theranostics therapeutics titanate nanotubes translational medicine triple negative breast cancer tumor microenvironment tumor spheroid disruption tumor targeting tumor vectorization tumour microenvironment tumour targeting ultrasound vectorization VEGF verteporfin viral nanoparticles vitamin B2 VX2 tumor Vδ2 T cells yet reasonably common within the subject discipline zoledronic acid β-cyclodextrin nanosponges |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557114703321 |
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Hoskins Clare
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential
| Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential |
| Autore | Pitsikas Nikolaos |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (171 p.) |
| Soggetto topico | Medicine and Nursing |
| Soggetto non controllato |
affron®
anesthetic ketamine anticancer activity antioxidant anxiety apoptosis autophagy cancer chemoprevention clinical trials colitis colorectal cancer crocetin crocin crocins Crocus sativus Crocus sativus L. Crocus sativus L. (Iridaceae) cytokines depression dietary supplement DNA damage and repair fertility preservation flumazenil fraction glucose gut microbiota HCT116 HR MS HuR inflammatory bowel disease insulin memory metabolomics MLH1 MSH3 n/a neuroprotective activity nutraceutical oxidative stress P2X7 receptor patents pck1 picrocrocin pubertal testis radiotherapy rat reversed-phase UPLC saffron safranal schizophrenia SIRT1 X-rays β-pancreatic cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Crocus sativus L. Extract and Its Constituents |
| Record Nr. | UNINA-9910557644303321 |
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Pitsikas Nikolaos
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Current Insights on Lipid-Based Nanosystems
| Current Insights on Lipid-Based Nanosystems |
| Autore | Silva Ana Catarina |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (368 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
Echinococcus granulosus
scolicidal nanoliposome juglone apoptotic activity hydrogel SLNs nose-to-brain delivery mucoadhesion quality by design antioxidant activity nasal administration nanostructured lipid carriers solid lipid nanoparticles in vitro cell cultures 3D nasal casts lung cancer targeted drug delivery lipid-based nanocarriers pulmonary delivery dry powder inhalers aerosols liposomes nanoemulsions nanotechnology biologically active compounds dermal drug delivery polyphenols phytophenols skin permeation chemotherapy radiotherapy active targeting passive targeting tumor immunoconjugate traditional liposome stealth liposome triggered release limitations of liposomes drug transfer in vitro release colloidal drug carriers lipid nanoparticles hydrogel beads cholesteryl nonanoate bovine serum albumin skin diseases lipid-based nanosystems cream ointment gel pH-sensitive liposome imidazole anticancer drug delivery multicellular spheroids dapagliflozin Box-Behnken design FTIR DSC XRD SEM AFM in vitro Franz diffusion cells lipid-based nanoparticles nanocarrier surface charge delivery systems chronic treatment mice anti-oxidant activity hepatoprotective effect phospholipid phytosomes Silymarin Colorectal Cancer Niosomes Oxaliplatin Paclitaxel d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) therapeutic nucleic acids schizophrenia quetiapine fumarate glycerosomes central composite rotatable design bioavailability pharmacokinetic |
| ISBN | 3-0365-6165-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639995103321 |
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Silva Ana Catarina
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications
| Cytobiology of Human Prostate Cancer Cells and Its Clinical Applications |
| Autore | Ishii Kenichiro |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 online resource (184 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
abiraterone
AKR1C3 androgen deprivation therapy androgen receptor androgen receptor dependency androgen sensitivity animal model apoptosis autophagy cabazitaxel CAF castration resistant prostate cancer castration-resistant prostate cancer Caveolin-1 CCL2 CCL22 CCL5 chemotherapy CW069 cytokine diet docetaxel docetaxel resistance enzalutamide EPI-002 epigenetics fat fibroblast fibroblast growth factor fibroblast growth factor receptor fibroblast-dependent androgen receptor activation fibroblasts G1 cell cycle arrest high-fat diet hormone-naïve prostate cancer immune cells immunohistochemistry in vitro in vivo inflammation KIFC1 LSD1 migration mouse n/a obesity P-glycoprotein pirfenidone prostate cancer prostate-specific antigen radiotherapy resistance splice variant testosterone TGFβ1 time to PSA nadir tissue microarray TP53-regulated inhibitor of apoptosis 1 tumour microenvironment tumour stroma |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557116703321 |
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Ishii Kenichiro
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Dedicated to the 55th Anniversary of G.B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences
| Dedicated to the 55th Anniversary of G.B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences |
| Autore | Dmitrenok Pavel S |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 online resource (234 p.) |
| Soggetto topico | Research and information: general |
| Soggetto non controllato |
1,4-naphthoquinones
actinoporin alginate utilization system alkaline phosphatase PhoA allylic thioether amino acids composition Anthenoides laevigatus anti-migratory activity antibiotic activity antibiotic stress anticancer activity bilayer lipid membrane cerebrosides Cobetia amphilecti Cobetia crustatorum Cobetia litoralis Cobetia marina Cobetia pacifica colorectal cancer cytotoxic activity cytotoxicity domoic acid dysiherbaine echinochrome A enzyme inhibition ESI-MS flavonoids fusion protein GC-MS genomes glass sponge glycosphingolipids green fluorescent protein Heteractis crispa histochrome HPLC-DAD-MS identification markers inclusion bodies isomalabaricanes kainic acid lanosterol 14-alpha demethylase marine bacteria marine sponge mass spectra molecular docking n/a neodysiherbaine A NMR NMR spectra orthologs oxidative degradation paralogs peroxidation products phenotypic heterogeneity phlorethols phlorotannins polyhydroxylated steroids polysaccharide lyase family 7 pore-forming activity porin porin gene expression quinoid compounds quinone-sugar conjugates radiosensitizer radiotherapy recombinant phospholipase A1 sea anemone soft agar assay spatial structure spectral titration starfish Stelletta sp structure elucidation surface plasmon resonance terpenoid thioglycosides whole genome sequence Yersinia pseudotuberculosis Zobellia |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557717403321 |
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Dmitrenok Pavel S
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Delivery of Molecules Using Nanoscale Systems for Cancer Treatment and/or Diagnosis
| Delivery of Molecules Using Nanoscale Systems for Cancer Treatment and/or Diagnosis |
| Autore | Franco Marina Santiago |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (302 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
nanostructured lipid carriers
doxorubicin mucositis cell internalization albumin BSA CPP gold nanorods gold nanoprisms arginine-rich peptide glutathione nanoparticles oxidative stress breast cancer gastric cancer nanoparticle fucoidan d-alpha-tocopherylpoly (ethylene glycol) succinate combination chemotherapy G-quadruplex nucleolin DNA nanocages intracellular localization cancer targeting molecular dynamics simulations mesoporous silica nanoparticles radiotherapy immunotherapy tumor microenvironment abscopal effect magnetofection in vivo magnetic nanoparticles iron oxide gene delivery gene vectors codelivery nanocarriers photodynamic therapy anticancer therapies combination therapy phthalocyanine uterine cervical neoplasms photochemotherapy in vitro in vivo nanocarrier polyplexes siRNA delivery glioblastoma therapy amphiphilic poly(α)glutamate P-selectin prodrug drug delivery targeted therapy chemotherapy prostate cancer prostate-specific membrane antigen targeted delivery encapsulation cabazitaxel nanocarriers nanosystems radiosensitizer hypoxia synergism cancer photothermal therapy combined antitumor effect oxygenation hydrogel hypoxic tumor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595074103321 |
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Franco Marina Santiago
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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